Research & Literature

Lifestyle Intervention in Gastroesophageal Reflux Disease.

Ness-Jensen E, Hveem K, El-Serag H, Lagergren J

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2016; (14(2)):175-82.e1-3.

Esomeprazole for the Treatment of Erosive Esophagitis in Children: An International, Multicenter, Randomized, Parallel-Group, Double-Blind (for Dose) Study.

Tolia V, Youssef NN, Gilger MA, et al.

Journal of pediatric gastroenterology and nutrition 2015; (60 Suppl 1()):S24-30 doi:10.1097/01.mpg.0000469419.29000.94.

Healing of Erosive Esophagitis and Improvement of Symptoms of Gastroesophageal Reflux Disease After Esomeprazole Treatment in Children 12 to 36 Months Old.

Tolia V, Gilger MA, Barker PN, Illueca M

Journal of pediatric gastroenterology and nutrition 2015; (60 Suppl 1()):S31-6 doi:10.1097/MPG.0b013e3181ddcf11.

Association of Visceral Fat Area, Smoking, and Alcohol Consumption with Reflux Esophagitis and Barrett's Esophagus in Japan.

Matsuzaki J, Suzuki H, Kobayakawa M, et al.

PloS one 2015; (10(7)):e0133865 doi:10.1371/journal.pone.0133865.

The binding selectivity of vonoprazan (TAK-438) to the gastric H+, K+ -ATPase.

Scott DR, Munson KB, Marcus EA, et al.

Alimentary pharmacology & therapeutics 2015; (42(11-12)):1315-26 doi:10.1111/apt.13414.

[Minimal Change Esophagitis].

Ryu HS, Choi SC

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 2016; (67(1)):4-7 doi:10.4166/kjg.2016.67.1.4.

The management of gastro-oesophageal reflux disease.

Keung C, Hebbard G

Australian prescriber 2016; (39(1)):6-10 doi:10.18773/austprescr.2016.003.

Impact of night-shift work on the prevalence of erosive esophagitis in shipyard male workers.

Chung TH, Lee J, Kim MC

International archives of occupational and environmental health 2016; (89(6)):961-6 doi:10.1007/s00420-016-1130-x.

Association of Acute Gastroesophageal Reflux Disease With Esophageal Histologic Changes.

Dunbar KB, Agoston AT, Odze RD, et al.

JAMA 2016; (315(19)):2104-12 doi:10.1001/jama.2016.5657.

Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2015.

Iwakiri K, Kinoshita Y, Habu Y, et al.

Journal of gastroenterology 2016; (51(8)):751-67 doi:10.1007/s00535-016-1227-8.

Long peptic strictures of the esophagus due to reflux esophagitis: a case report.

Yamasaki Y, Ozawa S, Oguma J, et al.

Surgical case reports 2016; (2(1)):64 doi:10.1186/s40792-016-0190-1.

Barrett's oesophagus: epidemiology, diagnosis and clinical management.

Whiteman DC, Kendall BJ

The Medical journal of Australia 2016; (205(7)):317-24 doi:10.5694/mja16.00796.

Diagnosis and Management of Low-Grade Dysplasia in Barrett's Esophagus: Expert Review From the Clinical Practice Updates Committee of the American Gastroenterological Association.

Wani S, Rubenstein JH, Vieth M, Bergman J

Gastroenterology 2016; (151(5)):822-835 doi:10.1053/j.gastro.2016.09.040.

Clinical symptom tool that raises the index of suspicion for eosinophilic oesophagitis in adults and drives earlier biopsy for definitive diagnosis.

von Arnim U, Röhl FW, Miehlke S, et al.

Alimentary pharmacology & therapeutics 2017; (45(3)):417-426 doi:10.1111/apt.13869.

Diagnosis of gastro-oesophageal reflux disease is enhanced by adding oesophageal histology and excluding epigastric pain.

Vakil N, Vieth M, Wernersson B, et al.

Alimentary pharmacology & therapeutics 2017; (45(10)):1350-1357 doi:10.1111/apt.14028.

A new paradigm for GERD pathogenesis. Not acid injury, but cytokine-mediated inflammation driven by HIF-2α: a potential role for targeting HIF-2α to prevent and treat reflux esophagitis.

Souza RF, Bayeh L, Spechler SJ, et al.

Current opinion in pharmacology 2017; (37()):93-99 doi:10.1016/j.coph.2017.10.004.

Vonoprazan treatment improves gastrointestinal symptoms in patients with gastroesophageal reflux disease.

Shinozaki S, Osawa H, Hayashi Y, et al.

The Kaohsiung journal of medical sciences 2017; (33(12)):616-622 doi:10.1016/j.kjms.2017.07.004.

The role of lifestyle changes in gastroesophageal reflux diseases treatment.

Dağlı Ü, Kalkan İH

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2017; (28(Suppl 1)):S33-S37 doi:10.5152/tjg.2017.10.

Medical treatment of gastroesophageal reflux disease.

Bor S, Kalkan İH

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 2017; (28(Suppl 1)):S48-S52 doi:10.5152/tjg.2017.13.

Lack of correlation between gastroesophageal reflux disease symptoms and esophageal lesions after sleeve gastrectomy.

Soricelli E, Casella G, Baglio G, et al.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2018; (14(6)):751-756 doi:10.1016/j.soard.2018.02.008.

Long-term outcomes of patients with symptomatic gastroesophageal reflux disease treated with vonoprazan.

Shinozaki S, Osawa H, Kobayashi Y, et al.

Scandinavian journal of gastroenterology 2018; (53(8)):897-904 doi:10.1080/00365521.2018.1486883.

Some of the effective factors in the pathogenesis of gastro-oesophageal reflux disease.

Nejat Pish-Kenari F, Qujeq D, Maghsoudi H

Journal of cellular and molecular medicine 2018; (22(12)):6401-6404 doi:10.1111/jcmm.13939.

Revisiting Montreal: New Insights into Symptoms and Their Causes, and Implications for the Future of GERD.

Hungin APS, Molloy-Bland M, Scarpignato C

The American journal of gastroenterology 2019; (114(3)):414-421 doi:10.1038/s41395-018-0287-1.

Endoscopy - esophagography.

Horikoshi T

Nihon rinsho. Japanese journal of clinical medicine 2016; (74(8)):1280-1284.

Esophagitis in Pediatric Esophageal Atresia: Acid May Not Always Be the Issue.

Yasuda JL, Clark SJ, Staffa SJ, et al.

Journal of pediatric gastroenterology and nutrition 2019; (69(2)):163-170 doi:10.1097/MPG.0000000000002336.

The potential role of potassium-competitive acid blockers in the treatment of gastroesophageal reflux disease.

Scarpignato C, Hunt RH

Current opinion in gastroenterology 2019; (35(4)):344-355 doi:10.1097/MOG.0000000000000543.

Optimizing Management of Patients With Barrett's Esophagus and Low-Grade or No Dysplasia Based on Comparative Modeling.

Omidvari AH, Ali A, Hazelton WD, et al.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2020; (18(9)):1961-1969 doi:10.1016/j.cgh.2019.11.058.

Erosive Esophagitis Portends a Benign Clinical Course in the Majority of Patients.

Bi D, Katzka DA, Lavey CJ, et al.

Digestive diseases and sciences 2020; (65(11)):3244-3252 doi:10.1007/s10620-019-06027-1.

The Impact of the Gastric Twist on Esophagitis Progression After Sleeve Gastrectomy: Mid-Term Endoscopic Findings.

Ferraz ÁAB, da Silva JD, Santa-Cruz F, et al.

Obesity surgery 2020; (30(11)):4452-4458 doi:10.1007/s11695-020-04838-0.

Intralesional steroid injections in addition to endoscopic dilation in benign refractory esophageal strictures : a systematic review.

Henskens N, Wauters L, Vanuytsel T

Acta gastro-enterologica Belgica 2020; (83(3)):432-440.

A narrative review of Barrett's esophagus in 2020, molecular and clinical update.

Dam AN, Klapman J

Annals of translational medicine 2020; (8(17)):1107 doi:10.21037/atm-20-4406.

Epidemiology of Barrett's Esophagus and Esophageal Adenocarcinoma: Implications for Screening and Surveillance.

Cook MB, Thrift AP

Gastrointestinal endoscopy clinics of North America 2021; (31(1)):1-26 doi:10.1016/j.giec.2020.08.001.

Gastroesophageal Reflux Disease: A Review.

Maret-Ouda J, Markar SR, Lagergren J

JAMA 2020; (324(24)):2536-2547 doi:10.1001/jama.2020.21360.

The Incidence of Erosive Esophagitis as a Complication of Pediatric Diabetic Ketoacidosis.

Agrawal S, Uysal S, Fredette M, et al.

Case reports in endocrinology 2021; (2021()):6636383 doi:10.1155/2021/6636383.

Therapeutic effect of laparoscopic fundoplication for patients with GERD from the viewpoint of Lyon Consensus.

Hoshino M, Omura N, Yano F, et al.

Esophagus : official journal of the Japan Esophageal Society 2021; (18(4)):915-921 doi:10.1007/s10388-021-00843-z.

Inter-observer variability of experts and trainees for the diagnosis of reflux esophagitis: Comparison of linked color imaging, blue laser imaging, and white light imaging.

Lee SP, Kae SH, Jang HJ, et al.

Journal of digestive diseases 2021; (22(7)):425-432 doi:10.1111/1751-2980.13023.

Novel impedance-pH parameters are associated with proton pump inhibitor response in patients with inconclusive diagnosis of gastro-oesophageal reflux disease according to Lyon Consensus.

Ribolsi M, Frazzoni M, Marabotto E, et al.

Alimentary pharmacology & therapeutics 2021; (54(4)):412-418 doi:10.1111/apt.16481.

Risk factors of erosive esophagitis and barrett's esophagus in patients with reflux symptoms.

Asreah RH, Abdullhameed A

Medical journal of the Islamic Republic of Iran 2021; (35()):75 doi:10.47176/mjiri.35.75.

2020 Seoul Consensus on the Diagnosis and Management of Gastroesophageal Reflux Disease.

Jung HK, Tae CH, Song KH, et al.

Journal of neurogastroenterology and motility 2021; (27(4)):453-481 doi:10.5056/jnm21077.

The evolution of endoscopic therapy for Barrett's esophagus.

Condon A, Muthusamy VR

Therapeutic advances in gastrointestinal endoscopy 2021; (14()):26317745211051834 doi:10.1177/26317745211051834.

ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease.

Katz PO, Dunbar KB, Schnoll-Sussman FH, et al.

The American journal of gastroenterology 2022; (117(1)):27-56 doi:10.14309/ajg.0000000000001538.

Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2021.

Iwakiri K, Fujiwara Y, Manabe N, et al.

Journal of gastroenterology 2022; (57(4)):267-285 doi:10.1007/s00535-022-01861-z.

Applying Lyon Consensus criteria in the work-up of patients with proton pump inhibitory-refractory heartburn.

Frazzoni M, Frazzoni L, Ribolsi M, et al.

Alimentary pharmacology & therapeutics 2022; (55(11)):1423-1430 doi:10.1111/apt.16838.

Pathophysiology of Dysphagia in Eosinophilic Esophagitis: Causes, Consequences, and Management.

Young E, Philpott H

Digestive diseases and sciences 2022; (67(4)):1101-1115 doi:10.1007/s10620-022-07419-6.

Pharmacodynamics and Pharmacokinetics of the Potassium-Competitive Acid Blocker Vonoprazan and the Proton Pump Inhibitor Lansoprazole in US Subjects.

Laine L, Sharma P, Mulford DJ, et al.

The American journal of gastroenterology 2022; (117(7)):1158-1161 doi:10.14309/ajg.0000000000001735.

The role of endoscopy in the management of gastroesophageal reflux disease.

Kuribayashi S, Hosaka H, Nakamura F, et al.

DEN open 2022; (2(1)):e86 doi:10.1002/deo2.86.

Diagnosis and Management of Barrett's Esophagus: An Updated ACG Guideline.

Shaheen NJ, Falk GW, Iyer PG, et al.

The American journal of gastroenterology 2022; (117(4)):559-587 doi:10.14309/ajg.0000000000001680.

Use of vonoprazan, a novel potassium-competitive acid blocker, for the treatment of proton pump inhibitor-refractory reflux esophagitis in patients with systemic sclerosis.

Shirai Y, Kawami N, Iwakiri K, Kuwana M

Journal of scleroderma and related disorders 2022; (7(1)):57-61 doi:10.1177/23971983211021747.

Comparison in Adherence to Treatment between Patients with Mild-Moderate and Severe Reflux Esophagitis: A Prospective Study.

Mari A, Na'amnih W, Gahshan A, et al.

Journal of clinical medicine 2022; (11(11)) doi:10.3390/jcm11113196.

Clinical significance of gastroesophageal reflux disease with minimal change: a multicenter prospective observational study.

Manabe N, Joh T, Higuchi K, et al.

Scientific reports 2022; (12(1)):15036 doi:10.1038/s41598-022-19408-w.

Laparoscopic antireflux surgery or PPIs in the management of reflux-related esophageal stricture.

Li ZT, Kong XL, Zhang R, et al.

Surgical endoscopy 2023; (37(2)):1077-1085 doi:10.1007/s00464-022-09564-5.

Vonoprazan Versus Lansoprazole for Healing and Maintenance of Healing of Erosive Esophagitis: A Randomized Trial.

Laine L, DeVault K, Katz P, et al.

Gastroenterology 2023; (164(1)):61-71 doi:10.1053/j.gastro.2022.09.041.

Ambulatory pH-Impedance Findings Confirm That Grade B Esophagitis Provides Objective Diagnosis of Gastroesophageal Reflux Disease.

Visaggi P, Del Corso G, Gyawali CP, et al.

The American journal of gastroenterology 2023; (118(5)):794-801 doi:10.14309/ajg.0000000000002173.

Endoscopic Grading as a Predictor to Develop Strictures in Corrosive Esophagitis in Children.

Badiu Tisa I, Pepelea L, Pirvan A, et al.

Journal of clinical medicine 2023; (12(4)) doi:10.3390/jcm12041699.

Diagnosis and Management of Barrett's Esophagus.

Mejza M, Małecka-Wojciesko E

Journal of clinical medicine 2023; (12(6)) doi:10.3390/jcm12062141.

The Relationship between Gastroesophageal Reflux Disease and Chronic Kidney Disease.

Wang X, Wright Z, Patton-Tackett ED, Song G

Journal of personalized medicine 2023; (13(5)) doi:10.3390/jpm13050827.

Quality of life and severity of symptoms among patients with various degrees of reflux esophagitis: a prospective study.

Mari A, Na'amnih W, Ghantous L, et al.

Scientific reports 2023; (13(1)):13970 doi:10.1038/s41598-023-41332-w.

Esophagogastrectomy for Long-Segment Recurrent Esophageal Stricture Following Hyperemesis Gravidarum.

Chong Tai LI, Anand G, Singh SP

Cureus 2023; (15(7)):e42489 doi:10.7759/cureus.42489.

Updates to the modern diagnosis of GERD: Lyon consensus 2.0.

Gyawali CP, Yadlapati R, Fass R, et al.

Gut 2024; (73(2)):361-371 doi:10.1136/gutjnl-2023-330616.

Role of endoscopy in gastroesophageal reflux disease.

Simadibrata DM, Lesmana E, Fass R

Clinical endoscopy 2023; (56(6)):681-692 doi:10.5946/ce.2023.182.

Comparative Efficacy of P-CAB vs Proton Pump Inhibitors for Grade C/D Esophagitis: A Systematic Review and Network Meta-analysis.

Zhuang Q, Chen S, Zhou X, et al.

The American journal of gastroenterology 2024; (119(5)):803-813 doi:10.14309/ajg.0000000000002714.

AGA Clinical Practice Guideline on Endoscopic Eradication Therapy of Barrett's Esophagus and Related Neoplasia.

Rubenstein JH, Sawas T, Wani S, et al.

Gastroenterology 2024; (166(6)):1020-1055 doi:10.1053/j.gastro.2024.03.019.

Comparison of Los Angeles Grades of Erosive Esophagitis Scored by Local Investigators vs Central Adjudicators in a Clinical Trial.

Spechler SJ, Laine L, DeVault KR, et al.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2024; (22(12)):2526-2528.e1 doi:10.1016/j.cgh.2024.05.007.

Potassium-competitive acid blockers and proton-pump inhibitors for healing of erosive esophagitis: a systematic review and network meta-analysis.

Liu Y, Gao Z, Hou X

Therapeutic advances in gastroenterology 2024; (17()):17562848241251567 doi:10.1177/17562848241251567.

Efficacy and Safety of Potassium-competitive Acid Blockers Versus Proton Pump Inhibitors in Treating Erosive Esophagitis: A Meta-analysis Based on Randomized Controlled Trials.

Fang Y, Lou D, Zhou J, et al.

Journal of clinical gastroenterology 2024; (58(9)):841-850 doi:10.1097/MCG.0000000000002052.

Association Between Different Metabolic Obesity Phenotypes and Erosive Esophagitis: A Retrospective Study.

He T, Sun XY, Tong MH, et al.

Diabetes, metabolic syndrome and obesity : targets and therapy 2024; (17()):3029-3041 doi:10.2147/DMSO.S471499.

Comparison of Potassium-Competitive Acid Blockers and Proton Pump Inhibitors in Patients With Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Agago DE, Hanif N, Ajay Kumar AS, et al.

Cureus 2024; (16(7)):e65141 doi:10.7759/cureus.65141.

The Clinical Spectrum of Gastroesophageal Reflux Disease: Facts and Fictions.

Marabotto E, Pasta A, Calabrese F, et al.

Visceral medicine 2024; (40(5)):242-249 doi:10.1159/000536583.

Efficacy of Step-Down Therapy Using Vonoprazan for Symptomatic Mild Reflux Esophagitis.

Ochiai Y, Kikuchi D, Hoteya S

Gastroenterology research and practice 2024; (2024()):5620034 doi:10.1155/grp/5620034.

Asymptomatic Erosive Esophagitis.

Du Y, Spencer A, Roy P, et al.

Digestive diseases and sciences 2025; (70(2)):462-468 doi:10.1007/s10620-024-08793-z.

Mean Nocturnal Baseline Impedance May Be Greater Than 2500 Ohms in Chinese Patients With GERD.

Wang D, Duan C, Zhang X, et al.

Neurogastroenterology and motility 2025; (37(2)):e14986 doi:10.1111/nmo.14986.

The Use of Antidepressants in Patients With Depression Is Associated With Gastroesophageal Reflux Disease and Disease Severity.

Saleh S, Fass R

Neurogastroenterology and motility 2025; (37(6)):e70010 doi:10.1111/nmo.70010.

The Los Angeles-B esophagitis is a conclusive diagnostic evidence for gastroesophageal reflux disease: the validation of Lyon Consensus 2.0.

Chen J, Dong P, Chen S, et al.

Gastroenterology report 2025; (13()):goaf004 doi:10.1093/gastro/goaf004.

Vonoprazan in Management of Refractory Gastroesophageal Reflux Disease: An Indian Expert Group Consensus Statements.

Abraham P, Choudhuri G, Deshmukh S, et al.

The Journal of the Association of Physicians of India 2025; (73(3)):e29-e36 doi:10.59556/japi.73.0878.

Prolonged wireless pH monitoring increases diagnostic yield in patients with reflux symptoms and borderline 24-hour impedance pH.

Hashimoto H, Piskorz MM, Olmos JI, et al.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 2025; (38(2)) doi:10.1093/dote/doaf030.

Investigation of the mechanism by which miR-223-3p inhibits reflux esophagitis through targeting the NLRP3 inflammasome.

Lin S, Zheng B, Wu R, et al.

BMC gastroenterology 2025; (25(1)):365 doi:10.1186/s12876-025-03836-9.

[Role of Potassium-competitive Acid Blockers in the Treatment of Gastric Acid-related Disorders].

Cho MY, Cho YK

The Korean journal of helicobacter and upper gastrointestinal research 2023; (23(3)):167-173 doi:10.7704/kjhugr.2023.0043.

Patients Presenting With Reflux Symptoms - Whom to Test and Whom to Treat?

Alon NL, Rodriguez TN, Fass R

The Korean journal of helicobacter and upper gastrointestinal research.. 2025; (25(1)):7-12 doi:10.7704/kjhugr.2025.0005.

Functional Esophageal Disorders in Children.

Puri NB

Gastroenterology clinics of North America 2025; (54(3)):503-510 doi:10.1016/j.gtc.2025.06.001.

Can the Mean Nocturnal Baseline Impedance/Acid Exposure Time Ratio Serve as a Novel Parameter for the Definitive Diagnosis of Pathological Reflux?

Eroğlu Haktanır A, Çelebi A

Journal of clinical medicine 2025; (14(18)) doi:10.3390/jcm14186586.

Erosive Esophagitis Unveiled: A Retrospective Study of Epidemiology and Endoscopic Findings in Qassim, Saudi Arabia.

Albarrak A, Alsamani R, Alwattban RR, et al.

Cureus 2025; (17(10)):e93688 doi:10.7759/cureus.93688.

Dose and duration shape the efficacy of vonoprazan versus lansoprazole for erosive esophagitis: insights from meta-regression.

Huang PF, Chen HW, Liang YJ

Therapeutic advances in gastroenterology 2025; (18()):17562848251406098 doi:10.1177/17562848251406098.

[Modern Diagnostic Strategies for Gastroesophageal Reflux Disease: Focus on Lyon Consensus 2.0].

Lee TH

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 2026; (86(3)):193-198 doi:10.4166/kjg.2026.038.

Gastroesophageal Reflux Disease and Reflux-like Phenotypes: Using Lyon Consensus 2.0 to Guide Clinical Approach.

Schroeder MK, Gyawali CP

Journal of neurogastroenterology and motility 2026; (32(3)):326-336 doi:10.5056/jnm26021.