Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
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Haukeland University Hospital
Bergen, Norway
Mayo Clinic
Rochester, United States
Karolinska University Hospital
Stockholm, Sweden
University of Sheffield
Sheffield, United Kingdom
Sahlgrenska University Hospital
Gothenburg, Sweden
Sapienza University of Rome
Rome, Italy
University Hospitals Birmingham NHS Foundation Trust
Birmingham, United Kingdom
Karolinska Institutet
Stockholm, Sweden
Universitätsklinikum Würzburg
Würzburg, Germany
Newcastle University
Newcastle upon Tyne, United Kingdom
References
References (54)
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UK guidelines for the management of pituitary apoplexy.
Rajasekaran S, Vanderpump M, Baldeweg S, et al.
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Pituitary apoplexy: pathophysiology, diagnosis and management.
Glezer A, Bronstein MD
Archives of endocrinology and metabolism 2015; (59(3)):259-64.
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Postpartum pituitary apoplexy with isolated oculomotor nerve palsy: A rare medical emergency.
Raina S, Jearth V, Sharma A, et al.
Journal of neurosciences in rural practice 2015; (6(4)):598-600 doi:10.4103/0976-3147.165348.
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A case of pituitary apoplexy masquerading as subarachnoid hemorrhage.
Choudhury M, Eligar V, DeLloyd A, Davies JS
Clinical case reports 2016; (4(3)):255-7 doi:10.1002/ccr3.488.
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Pituitary apoplexy - bespoke patient management allows good clinical outcome.
Giritharan S, Gnanalingham K, Kearney T
Clinical endocrinology 2016; (85(3)):415-22 doi:10.1111/cen.13075.
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Surgical versus non-surgical treatment for pituitary apoplexy: A systematic review and meta-analysis.
Tu M, Lu Q, Zhu P, Zheng W
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DIAGNOSIS OF ENDOCRINE DISEASE: Expanding the cause of hypopituitarism.
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European journal of endocrinology 2017; (176(6)):R269-R282.
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Pituitary apoplexy: a rare complication of leuprolide therapy in prostate cancer treatment.
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BMJ case reports 2017; (2017()) doi:10.1136/bcr-2016-218514.
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Postoperative Neurologic Outcome in Patients with Pituitary Apoplexy After Transsphenoidal Surgery.
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Pituitary Ring Sign Plus Sphenoid Sinus Mucosal Thickening: Neuroimaging Signs of Pituitary Apoplexy.
Vaphiades MS
Neuro-ophthalmology (Aeolus Press) 2017; (41(6)):306-309 doi:10.1080/01658107.2017.1349807.
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Apoplexy in nonfunctioning pituitary adenomas.
Wildemberg LE, Glezer A, Bronstein MD, Gadelha MR
Pituitary 2018; (21(2)):138-144 doi:10.1007/s11102-018-0870-x.
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Acute pituitary disease in pregnancy: how to handle hypophysitis and Sheehan's syndrome.
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Clinical and biochemical characteristics of patients presenting with pituitary apoplexy.
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Endocrine connections 2018; (7(10)):1058-1066 doi:10.1530/EC-18-0255.
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Gestational pituitary apoplexy: Case series and review of the literature.
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Journal of gynecology obstetrics and human reproduction 2019; (48(10)):873-881 doi:10.1016/j.jogoh.2019.05.005.
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Pituitary apoplexy following endoscopic nasal surgery: A case report.
Harju T, Alanko J, Numminen J
SAGE open medical case reports 2019; (7()):2050313X19855867 doi:10.1177/2050313X19855867.
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Pituitary Apoplexy: Results of Surgical and Conservative Management Clinical Series and Review of the Literature.
Almeida JP, Sanchez MM, Karekezi C, et al.
World neurosurgery 2019; (130()):e988-e999 doi:10.1016/j.wneu.2019.07.055.
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Pituitary Apoplexy Following Systemic Anticoagulation.
Santos AR, Bello CT, Sousa A, et al.
European journal of case reports in internal medicine 2019; (6(12)):001254 doi:10.12890/2019_001254.
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Chronic Sheehan's Syndrome - A Differential to be Considered in Clinical Practice in Women with a History of Postpartum Hemorrhage.
Jose M, Amir S, Desai R
Cureus 2019; (11(12)):e6290 doi:10.7759/cureus.6290.
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Pituitary Apoplexy Case Series: Outcomes After Endoscopic Endonasal Transsphenoidal Surgery at a Single Tertiary Center.
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World neurosurgery 2020; (137()):e366-e372 doi:10.1016/j.wneu.2020.01.204.
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Pituitary Apoplexy Accompanying Temporal Lobe Seizure as a Complication.
Shijo K, Yoshimura S, Mori F, et al.
World neurosurgery 2020; (138()):153-157 doi:10.1016/j.wneu.2020.02.148.
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Guidance for the prevention and emergency management of adult patients with adrenal insufficiency.
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Risk factors for the incidence of apoplexy in pituitary adenoma: a single-center study from southwestern China.
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A key role for conservative treatment in the management of pituitary apoplexy.
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Endocrine 2021; (71(1)):168-177 doi:10.1007/s12020-020-02499-8.
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Adrenal crisis precipitated by influenza A led to the diagnosis of Sheehan's syndrome 18 years after postpartum hemorrhage.
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Clinical case reports 2020; (8(12)):3082-3087 doi:10.1002/ccr3.3355.
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Endocrine connections 2021; (10(2)):171-179.
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Perioperative management of Fontan operation for the child with panhypopituitarism: a case report.
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Key Factors Related to Internal Carotid Artery Stenosis Associated with Pituitary Apoplexy.
Teramoto S, Tahara S, Kondo A, Morita A
World neurosurgery 2021; (149()):e447-e454 doi:10.1016/j.wneu.2021.02.005.
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Apoplexy of microprolactinomas during pregnancy: report of five cases and review of the literature.
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European journal of endocrinology 2021; (185(1)):99-108.
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A Case of Sheehan Syndrome 7 Years Postpartum with Transaminitis and Hyperlipidemia.
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The American journal of case reports 2021; (22()):e930908 doi:10.12659/AJCR.930908.
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A 45-year-old female patient with Sheehan's syndrome presenting with imminent adrenal crisis: a case report.
Genetu A, Anemen Y, Abay S, et al.
Journal of medical case reports 2021; (15(1)):229 doi:10.1186/s13256-021-02827-0.
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Acute Sterile Meningitis as a Primary Manifestation of Pituitary Apoplexy.
Tumyan G, Mantha Y, Gill R, Feldman M
AACE clinical case reports 2021; (7(2)):117-120 doi:10.1016/j.aace.2020.11.024.
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A Rare Case of Myxedema Coma Presenting as Bradycardia and Hypotension Secondary to Pituitary Apoplexy.
Bhogal S, Patel N, Mawa K, et al.
Cureus 2021; (13(5)):e15196 doi:10.7759/cureus.15196.
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Case Report: Polyneuropathy Pituitary Apoplexy with Normal Perimetry and Initially Normal Neuroimaging.
Sowka JW, Wu TH
Optometry and vision science : official publication of the American Academy of Optometry 2021; (98(10)):1139-1142 doi:10.1097/OPX.0000000000001786.
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Towards a pituitary apoplexy classification based on clinical presentation and patient journey.
Guijt MC, Zamanipoor Najafabadi AH, Notting IC, et al.
Endocrine 2022; (76(1)):132-141 doi:10.1007/s12020-022-02983-3.
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Visual and Hormone Outcomes in Pituitary Apoplexy: Results of a Single Surgeon, Single Institution 15-Year Retrospective Review and Pooled Data Analysis.
Seaman SC, Dougherty MC, Zanaty M, et al.
Journal of neurological surgery. Part B, Skull base 2021; (82(4)):392-400 doi:10.1055/s-0040-1713104.
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Spot the adenoma after pituitary apoplexy following a SARS-CoV-2 vaccination.
Finsterer J, Scorza FA, Almeida AG
Brain hemorrhages 2022; doi:10.1016/j.hest.2022.10.001.
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Acute Sheehan's Syndrome Presenting with Hyponatremia Followed by a Spontaneous Pregnancy.
Pineyro MM, Diaz L, Guzzetti M, et al.
Case reports in endocrinology 2022; (2022()):9181365 doi:10.1155/2022/9181365.
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Pituitary apoplexy score, toward standardized decision-making: a descriptive study.
Salle H, Cane M, Rocher M, et al.
Pituitary 2024; (27(1)):77-87 doi:10.1007/s11102-023-01372-x.
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Pituitary apoplexy as a mimicker of infectious meningitis in an adolescent female patient.
Enns JP, Al-Khindi T, Wu C, et al.
Annals of internal medicine. Clinical cases 2023; (2(9)) doi:10.7326/aimcc.2022.1328.
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Delayed Sheehan's syndrome diagnosed during the evaluation of secondary infertility: A case report.
Saxena S, Verma V, Samadarshi S, et al.
Clinical case reports 2024; (12(2)):e8521 doi:10.1002/ccr3.8521.
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Pituitary Apoplexy: An Updated Review.
Iglesias P
Journal of clinical medicine 2024; (13(9)) doi:10.3390/jcm13092508.
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Pituitary Apoplexy and the Current Understanding of Its Management: A Meta-Analysis of 908 Patients.
Marin-Castañeda LA, Gorbachev J, Lopez-Zepeda PT, et al.
World neurosurgery 2024; (190()):371-385.e1 doi:10.1016/j.wneu.2024.07.103.
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The role of intervention timing and treatment modality in visual recovery following pituitary apoplexy: a systematic review and meta-analysis.
Brown NJ, Patel S, Gendreau J, Abraham ME
Journal of neuro-oncology 2024; (170(3)):469-482 doi:10.1007/s11060-024-04717-z.
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Quality of life in non-functioning pituitary adenoma: A systematic review.
Castle-Kirszbaum M, McCormack A, Kam J, et al.
Neurosurgical review 2024; (47(1)):867 doi:10.1007/s10143-024-03126-0.
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Contemporaneous Presentation of Ocular Myasthenia Gravis With Pituitary Apoplexy: A Diagnostic Dilemma.
Perera I, Fernando H, Janaka K, et al.
Cureus 2025; (17(3)):e80666 doi:10.7759/cureus.80666.
PMID: 40236367 - 50
Pituitary apoplexy in the setting of severe headache and unconsciousness.
Qureshi M, Thozhuthumparambil KP
BMJ case reports 2025; (18(5)) doi:10.1136/bcr-2024-263585.
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Adrenal Insufficiency in Adults: A Review.
Vaidya A, Findling J, Bancos I
JAMA 2025; (334(8)):714-725 doi:10.1001/jama.2025.5485.
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Pituitary apoplexy within a prolactin-secreting macroadenoma in a child: A rare clinical entity with radiological correlation.
Mouhcine Y, Lahjouji O, Ouazzani H, et al.
Radiology case reports 2025; (20(11)):5583-5589 doi:10.1016/j.radcr.2025.07.066.
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Characteristics of the Early Manifestations and the Sequential Changes of Magnetic Resonance Imaging in Acute Sheehan's Syndrome: A Case Report and Literature Review.
Miura A, Kurihara Y, Kitada K, et al.
Cureus 2025; (17(9)):e92275 doi:10.7759/cureus.92275.
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Management of endocrine disease: update on the management of pituitary apoplexy.
Biagetti B, Marques P, Ntali G, et al.
European journal of endocrinology 2026; (194(2)):R49-R66 doi:10.1093/ejendo/lvag034.
PMID: 41699778