Research & Literature

CT characteristics in 24 patients with POEMS syndrome.

Shi X, Hu S, Luo X, et al.

Acta radiologica (Stockholm, Sweden : 1987) 2016; (57(1)):51-7 doi:10.1177/0284185114564614.

Polyneuropathy improvement following autologous stem cell transplantation for POEMS syndrome.

Karam C, Klein CJ, Dispenzieri A, et al.

Neurology 2015; (84(19)):1981-7 doi:10.1212/WNL.0000000000001565.

Renal impairment in patients with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes syndrome: incidence, treatment and outcome.

Ye W, Wang C, Cai QQ, et al.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2016; (31(2)):275-83 doi:10.1093/ndt/gfv261.

Thrombocytosis distinguishes POEMS syndrome from chronic inflammatory demyelinating polyneuropathy.

Naddaf E, Dispenzieri A, Mandrekar J, Mauermann ML

Muscle & nerve 2015; (52(4)):658-9 doi:10.1002/mus.24768.

POEMS syndrome: update on diagnosis, risk-stratification, and management.

Dispenzieri A

American journal of hematology 2015; (90(10)):951-62 doi:10.1002/ajh.24171.

Vascular endothelial growth factor as a predictive marker for POEMS syndrome treatment response: retrospective cohort study.

Misawa S, Sato Y, Katayama K, et al.

BMJ open 2015; (5(11)):e009157 doi:10.1136/bmjopen-2015-009157.

Bone lesions in Chinese POEMS syndrome patients: imaging characteristics and clinical implications.

Wang F, Huang X, Zhang Y, et al.

PeerJ 2016; (4()):e2294 doi:10.7717/peerj.2294.

Clinical spectrum of Castleman disease-associated neuropathy.

Naddaf E, Dispenzieri A, Mandrekar J, Mauermann ML

Neurology 2016; (87(23)):2457-2462 doi:10.1212/WNL.0000000000003405.

POEMS Syndrome: an Enigma.

Warsame R, Yanamandra U, Kapoor P

Current hematologic malignancy reports 2017; (12(2)):85-95 doi:10.1007/s11899-017-0367-0.

Osteolytic-variant POEMS syndrome: an uncommon presentation of "osteosclerotic" myeloma.

Clark MS, Howe BM, Glazebrook KN, et al.

Skeletal radiology 2017; (46(6)):817-823 doi:10.1007/s00256-017-2607-8.

POEMS syndrome: 2017 Update on diagnosis, risk stratification, and management.

Dispenzieri A

American journal of hematology 2017; (92(8)):814-829 doi:10.1002/ajh.24802.

Plexogenic pulmonary hypertension associated with POEMS syndrome.

Czeczok T, Lin P, Yi E

Respiratory medicine case reports 2017; (22()):168-170 doi:10.1016/j.rmcr.2017.08.011.

POEMS Syndrome: Therapeutic Options.

Jaccard A

Hematology/oncology clinics of North America 2018; (32(1)):141-151 doi:10.1016/j.hoc.2017.09.011.

[Analysis of clinical features of 23 patients with POEMS syndrome].

Hu P, Luo YY, Wu J, Gao LL

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 2017; (49(6)):985-989.

Efficacy and Long-Term Outcomes of Autologous Stem Cell Transplantation in POEMS Syndrome: A Nationwide Survey in Japan.

Kawajiri-Manako C, Sakaida E, Ohwada C, et al.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2018; (24(6)):1180-1186 doi:10.1016/j.bbmt.2018.01.026.

A prospective phase II study of low dose lenalidomide plus dexamethasone in patients with newly diagnosed polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome.

Li J, Huang XF, Cai QQ, et al.

American journal of hematology 2018; (93(6)):803-809 doi:10.1002/ajh.25100.

Clonal immunoglobulin λ light-chain gene rearrangements detected by next generation sequencing in POEMS syndrome.

Kawajiri-Manako C, Mimura N, Fukuyo M, et al.

American journal of hematology 2018; (93(9)):1161-1168 doi:10.1002/ajh.25213.

POEMS syndrome.

Keddie S, Lunn MP

Current opinion in neurology 2018; (31(5)):551-558 doi:10.1097/WCO.0000000000000610.

Raised VEGF: High sensitivity and specificity in the diagnosis of POEMS syndrome.

Pihan M, Keddie S, D'Sa S, et al.

Neurology(R) neuroimmunology & neuroinflammation 2018; (5(5)):e486 doi:10.1212/NXI.0000000000000486.

Prevalence and Course of Endocrinopathy in POEMS Syndrome.

Caimari F, Keddie S, Lunn MP, et al.

The Journal of clinical endocrinology and metabolism 2019; (104(6)):2140-2146 doi:10.1210/jc.2018-01516.

Proposal of new clinical diagnostic criteria for POEMS syndrome.

Suichi T, Misawa S, Sato Y, et al.

Journal of neurology, neurosurgery, and psychiatry 2019; (90(2)):133-137 doi:10.1136/jnnp-2018-318514.

Improvement of thyroid function in POEMS syndrome after combination therapy of lenalidomide and dexamethasone.

Yang H, Zhao H, Huang X, et al.

Leukemia & lymphoma 2019; (60(2)):483-487 doi:10.1080/10428194.2018.1485909.

POEMS syndrome: clinical update.

Brown R, Ginsberg L

Journal of neurology 2019; (266(1)):268-277 doi:10.1007/s00415-018-9110-6.

Effectiveness of pulmonary vasodilators on pulmonary hypertension associated with POEMS syndrome.

Ohashi K, Nishimura R, Sugimoto S, et al.

Respirology case reports 2019; (7(4)):e00411 doi:10.1002/rcr2.411.

Endocrine Manifestations in POEMS Syndrome: a case report and literature review.

Li H, Huang Y, Li Y, et al.

BMC endocrine disorders 2019; (19(1)):33 doi:10.1186/s12902-019-0355-6.

POEMS Syndrome: 2019 Update on diagnosis, risk-stratification, and management.

Dispenzieri A

American journal of hematology 2019; (94(7)):812-827 doi:10.1002/ajh.25495.

POEMS Syndrome: Bone Marrow, Laboratory, and Clinical Findings in 24 Korean Patients.

Shim H, Seol CA, Park CJ, et al.

Annals of laboratory medicine 2019; (39(6)):561-565 doi:10.3343/alm.2019.39.6.561.

Clinical and electrophysiological profiles in early recognition of polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes syndrome.

Wang Q, Liu P, Ji LL, et al.

Chinese medical journal 2019; (132(14)):1666-1672 doi:10.1097/CM9.0000000000000318.

Prevalence, clinical profiles, and prognosis of POEMS syndrome in Japanese nationwide survey.

Suichi T, Misawa S, Beppu M, et al.

Neurology 2019; (93(10)):e975-e983 doi:10.1212/WNL.0000000000008062.

POEMS syndrome: a rare cause of adrenal insufficiency in a young male.

Prokop J, Estorninho J, Marote S, et al.

Endocrinology, diabetes & metabolism case reports 2019; (2019()).

High rates of venous and arterial thrombotic events in patients with POEMS syndrome: results from the UCLH (UK) POEMS Registry.

Sayar Z, Weatherill A, Keddie S, et al.

Blood advances 2020; (4(10)):2139-2142 doi:10.1182/bloodadvances.2020001492.

Clinical characteristics, risk factors, and outcomes of POEMS syndrome: A longitudinal cohort study.

Keddie S, Foldes D, Caimari F, et al.

Neurology 2020; (95(3)):e268-e279 doi:10.1212/WNL.0000000000009940.

Atypical polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes syndrome without polyneuropathy: A case report.

Li Q, Xu F, Duan JF, Tang YF

Medicine 2020; (99(27)):e20812 doi:10.1097/MD.0000000000020812.

Ischemic stroke in patients with POEMS syndrome.

Feng J, Gao XM, Zhao H, et al.

Blood advances 2020; (4(14)):3427-3434 doi:10.1182/bloodadvances.2020001865.

Ischemic Stroke in a Patient With Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Protein, and Skin Changes Syndrome Treated With Lenalidomide.

Sodavarapu S, Mahajan A

Cureus 2020; (12(7)):e9346 doi:10.7759/cureus.9346.

POEMS syndrome: A multisystem clonal disorder.

Ali T, Qazilbash MH

European journal of haematology 2021; (106(1)):14-18 doi:10.1111/ejh.13514.

Endocrine Evaluation in POEMS Syndrome: A Cohort Study.

Yang H, Zhao H, Gao X, et al.

Frontiers in endocrinology 2020; (11()):536241 doi:10.3389/fendo.2020.536241.

Peripheral retinal leakage in POEMS syndrome.

Carey AR, Jeyaseelan P

International journal of retina and vitreous 2021; (7(1)):6 doi:10.1186/s40942-020-00278-1.

[POEMS syndrome: Diagnosis, stratification, treatments].

Talbot A, Jaccard A, Arnulf B

La Revue de medecine interne 2021; (42(5)):320-329 doi:10.1016/j.revmed.2021.02.007.

Update on the Diagnosis and Treatment of POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes) Syndrome: A Review.

Khouri J, Nakashima M, Wong S

JAMA oncology 2021; (7(9)):1383-1391 doi:10.1001/jamaoncol.2021.0586.

Cerebral large artery stenosis and occlusion in POEMS syndrome.

Sugiyama A, Yokota H, Misawa S, et al.

BMC neurology 2021; (21(1)):239 doi:10.1186/s12883-021-02260-2.

Pericardial Tamponade and Other Cardiac Complications in POEMS Syndrome.

Levene J, Murray N, Desai S, et al.

JACC. Case reports 2021; (3(2)):286-290 doi:10.1016/j.jaccas.2020.12.027.

Bortezomib plus dexamethasone as first-line therapy for patients with POEMS syndrome.

Gao XM, Yu YY, Zhao H, et al.

Annals of hematology 2021; (100(11)):2755-2761 doi:10.1007/s00277-021-04609-6.

A retrospective analysis of endocrinopathy manifestations in 136 Chinese patients with POEMS syndrome.

Shao Y, Zhang C, Wang X, et al.

Neuro endocrinology letters 2021; (42(5)):292-296.

POEMS syndrome causing left ventricular hypertrophy, myocardial dysfunction, and pericardial effusion: a case report.

Wang S, Wu X, Li H

European heart journal. Case reports 2022; (6(1)):ytab504 doi:10.1093/ehjcr/ytab504.

Unraveling unique features of plasma cell clones in POEMS syndrome with single-cell analysis.

Isshiki Y, Oshima M, Mimura N, et al.

JCI insight 2022; (7(20)).

Comprehensive Diagnosis and Management of POEMS Syndrome.

D'Sa S, Khwaja J, Keddie S, et al.

HemaSphere 2022; (6(11)):e796 doi:10.1097/HS9.0000000000000796.

Polyneuropathy organomegaly endocrinopathy M-protein and skin changes syndrome with ascites as an early-stage manifestation: A case report.

Zhou XL, Chang YH, Li L, et al.

World journal of clinical cases 2023; (11(1)):135-142 doi:10.12998/wjcc.v11.i1.135.

Regular assessment of serum vascular endothelial growth factor levels to monitor POEMS syndrome.

Gentile F, Terenghi F, Doneddu PE, et al.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2024; (45(2)):727-733 doi:10.1007/s10072-023-07064-5.

Long-Term Outcomes of Autologous Stem Cell Transplantation in Patients with Newly Diagnosed POEMS Syndrome.

Li AA, Gao XM, Zhao H, et al.

Transplantation and cellular therapy 2024; (30(2)):207.e1-207.e7 doi:10.1016/j.jtct.2023.11.001.

Pulmonary manifestations of POEM syndrome: a retrospective analysis of 282 cases.

Huang Y, Luo Y, Hou H, Gao J

BMC pulmonary medicine 2023; (23(1)):465 doi:10.1186/s12890-023-02741-9.

A Multicenter Analysis of Clinical Features and Long-Term Outcomes of POEMS Syndrome in Korea.

Kook HW, Jang JE, Min CK, et al.

Journal of Korean medical science 2024; (39(2)):e5 doi:10.3346/jkms.2024.39.e5.

Efficacy of bortezomib, cyclophosphamide, and dexamethasone for newly diagnosed POEMS syndrome patients.

Fang F, Lan XX, Hu RH, et al.

Therapeutic advances in neurological disorders 2024; (17()):17562864231219151 doi:10.1177/17562864231219151.

Detection of clonal plasma cells in POEMS syndrome using multiparameter flow cytometry.

Ishii A, Tsukamoto S, Mimura N, et al.

Scientific reports 2024; (14(1)):10362 doi:10.1038/s41598-024-61034-1.

Requirement of Repeated Serum VEGF Measurements in POEMS Syndrome.

Nomura T, Iwata I, Eguchi K, et al.

Internal medicine (Tokyo, Japan) 2025; (64(5)):769-773 doi:10.2169/internalmedicine.4086-24.

Case report: DKRd regimen in the treatment of newly diagnosed POEMS syndrome and literature review.

Wang J, Liao W, Liu Z, Kong D

Frontiers in oncology 2024; (14()):1417380 doi:10.3389/fonc.2024.1417380.

Dramatically elevated plasma vascular endothelial growth factor levels from influenza A infection in polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes syndrome: A case report.

Kannan A, Zhuo Y, Banerjee R

EJHaem 2024; (5(4)):842-844 doi:10.1002/jha2.965.

POEMS Syndrome.

Jaccard A, Pascal V, Magy L, Roussel M

Presse medicale (Paris, France : 1983) 2025; (54(1)):104270 doi:10.1016/j.lpm.2025.104270.

Growth Differentiation Factor-15 as a Potential Biomarker for Renal Involvement in POEMS Syndrome.

Huang Y, Chen J, Yao Y, et al.

International journal of nephrology and renovascular disease 2025; (18()):133-142 doi:10.2147/IJNRD.S507148.

POEMS syndrome presenting with Vibrio vulnificus-like cutaneous lesions: a CARE guidelines-compliant case report.

Li X, Lin B, Lin L, Song C

Frontiers in medicine 2025; (12()):1625877 doi:10.3389/fmed.2025.1625877.

Monoclonal-related neuropathies: diagnosis, prognosis, and outcomes.

Jaccard A, Magy L, Arnulf B, et al.

Hematology. American Society of Hematology. Education Program 2025; (2025(1)):385-392 doi:10.1182/hematology.2025000728.

Refractory ascites: unveiling POEMS syndrome as the underlying cause: a case report and literature review.

Liu S, He Y, Qin J, et al.

Frontiers in medicine 2025; (12()):1704902 doi:10.3389/fmed.2025.1704902.

Neurological Peculiarities of POEMS Syndrome: Experience From a Brazilian University Center.

Rosenstein RF, Soares Baima JP, Meneguin Pereira TD, et al.

Muscle & nerve 2026; (73(3)):421-426 doi:10.1002/mus.70114.

POEMS syndrome: a neuromuscular perspective.

Gonçalves TAP, Donadel CD, Frezatti RSS, et al.

Journal of neurology, neurosurgery, and psychiatry 2026; (97(4)):293-301 doi:10.1136/jnnp-2025-336633.

Atypical Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Protein, and Skin Changes (POEMS) Syndrome.

Bishara M, Homeniuk A, Patel A, et al.

Cureus 2026; (18(2)):e103791 doi:10.7759/cureus.103791.

When Foot Drop Tells a Bigger Story: POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Plasma Cell Disorder, and Skin Changes) Syndrome Revealed by Femoral Plasmacytoma.

Al-Anbagi U, Ahmed S, Telfah H, et al.

Cureus 2026; (18(2)):e103751 doi:10.7759/cureus.103751.

Thrombosis in Neuromuscular Medicine: Current Evidence, Unmet Needs, and Future Directions.

Quak ZX, Wang F, Tay SKH, et al.

Journal of clinical medicine 2026; (15(8)) doi:10.3390/jcm15082810.

[Recent advances in pathogenesis, diagnosis, and therapeutic strategies for POEMS syndrome].

Tsukamoto S

[Rinsho ketsueki] The Japanese journal of clinical hematology 2026; (67(5)):453-461 doi:10.11406/rinketsu.67.453.

Polyneuropathy, Organomegaly, Endocrinopathy, M-Protein, and Skin Changes (POEMS) Syndrome With Characteristic Muscle Biopsy Findings and Without M-Protein.

Yalovitser J, Seyam M, DeWitt J, et al.

The neurologist 2026; doi:10.1097/NRL.0000000000000688.