Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
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Launchpad Central (United States)
San Francisco, United States
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Huntsville, United States
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Paris, France
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Balıkesir, Türkiye
University of Turin
Turin, Italy
The Affiliated Yongchuan Hospital of Chongqing Medical University
Chongqing, China
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Ann Arbor, United States
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References
References (118)
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Adrenal venous sampling for primary aldosteronism: laboratory medicine best practice.
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Aldosterone to Renin Ratio as a Screening Instrument for Primary Aldosteronism in a Middle-Aged Population with Atrial Fibrillation.
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The Potential Role of Primary Care in Case Detection/Screening of Primary Aldosteronism.
Kline GA, Prebtani APH, Leung AA, Schiffrin EL
American journal of hypertension 2017; (30(12)):1147-1150 doi:10.1093/ajh/hpx064.
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Cardiovascular events and target organ damage in primary aldosteronism compared with essential hypertension: a systematic review and meta-analysis.
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The lancet. Diabetes & endocrinology 2018; (6(1)):41-50 doi:10.1016/S2213-8587(17)30319-4.
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Health-Related Quality of Life and Mental Health in Primary Aldosteronism: A Systematic Review.
Velema MS, de Nooijer AH, Burgers VWG, et al.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 2017; (49(12)):943-950 doi:10.1055/s-0043-121706.
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Aldosterone-Producing Cell Clusters in Normal and Pathological States.
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GENETICS IN ENDOCRINOLOGY: The expanding genetic horizon of primary aldosteronism.
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European journal of endocrinology 2018; (178(3)):R101-R111.
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Case detection in primary aldosteronism: high-diagnostic value of the aldosterone-to-renin ratio when performed under standardized conditions.
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Saline suppression test parameters may predict bilateral subtypes of primary aldosteronism.
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Clinical endocrinology 2018; (89(3)):308-313 doi:10.1111/cen.13757.
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Renal Outcomes in Medically and Surgically Treated Primary Aldosteronism.
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Is it time to screen all patients with hypertension for primary aldosteronism?
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The Medical journal of Australia 2018; (209(2)):57-59 doi:10.5694/mja17.00783.
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Factors Associated with Resolution of Hypertension after Adrenalectomy in Patients with Primary Aldosteronism.
Loh WJ, Lim DST, Loh LM, Kek PC
Endocrinology and metabolism (Seoul, Korea) 2018; (33(3)):355-363 doi:10.3803/EnM.2018.33.3.355.
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Cortisol Excess in Patients With Primary Aldosteronism Impacts Left Ventricular Hypertrophy.
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The Journal of clinical endocrinology and metabolism 2018; (103(12)):4543-4552 doi:10.1210/jc.2018-00617.
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Obesity as a Key Factor Underlying Idiopathic Hyperaldosteronism.
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A novel clinical nomogram to predict bilateral hyperaldosteronism in Chinese patients with primary aldosteronism.
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Clinical endocrinology 2019; (90(6)):781-788 doi:10.1111/cen.13962.
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Eplerenone Versus Spironolactone in Resistant Hypertension: an Efficacy and/or Cost or Just a Men's Issue?
Manolis AA, Manolis TA, Melita H, Manolis AS
Current hypertension reports 2019; (21(3)):22 doi:10.1007/s11906-019-0924-0.
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Mineralocorticoid Receptor Antagonists in Primary Aldosteronism.
Stavropoulos K, Papadopoulos C, Koutsampasopoulos K, et al.
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Success rate of adrenal venous sampling and predictors for success: a retrospective study.
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Polish journal of radiology 2019; (84()):e136-e141 doi:10.5114/pjr.2019.84178.
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Clinical outcomes after surgery for primary aldosteronism: Evaluation of the PASO-investigators' consensus criteria within a worldwide cohort of patients.
Vorselaars WMCM, van Beek DJ, Postma EL, et al.
Surgery 2019; (166(1)):61-68 doi:10.1016/j.surg.2019.01.031.
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Effect of unilateral adrenalectomy on the quality of life of patients with lateralized primary aldosteronism.
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BMC surgery 2019; (18(Suppl 1)):105 doi:10.1186/s12893-018-0432-1.
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Renal damage in primary aldosteronism: a systematic review and meta-analysis.
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Journal of hypertension 2020; (38(1)):3-12 doi:10.1097/HJH.0000000000002216.
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A combination of captopril challenge test after saline infusion test improves diagnostic accuracy for primary aldosteronism.
Lin C, Yang J, Fuller PJ, et al.
Clinical endocrinology 2020; (92(2)):131-137 doi:10.1111/cen.14134.
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Atrial fibrillation as presenting sign of primary aldosteronism: results of the Prospective Appraisal on the Prevalence of Primary Aldosteronism in Hypertensive (PAPPHY) Study.
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Journal of hypertension 2020; (38(2)):332-339 doi:10.1097/HJH.0000000000002250.
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Persistent severe hyperkalemia following surgical treatment of aldosterone-producing adenoma.
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Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 2020; (25()):17 doi:10.4103/jrms.JRMS_603_19.
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New advances in the diagnosis of primary aldosteronism.
Shen H, Xu ZX, Li QF
Chronic diseases and translational medicine 2020; (6(1)):1-5 doi:10.1016/j.cdtm.2019.12.009.
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Primary Aldosteronism in Patients in China With Recently Detected Hypertension.
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The Unrecognized Prevalence of Primary Aldosteronism: A Cross-sectional Study.
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Annals of internal medicine 2020; (173(1)):10-20 doi:10.7326/M20-0065.
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Evolution of the Primary Aldosteronism Syndrome: Updating the Approach.
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The Journal of clinical endocrinology and metabolism 2020; (105(12)) doi:10.1210/clinem/dgaa606.
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Long-term outcome success after operative treatment for primary aldosteronism.
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Surgery 2021; (169(3)):528-532 doi:10.1016/j.surg.2020.07.046.
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Update: Selective adrenal venous sampling (AVS) - Indication, technique, and significance.
Loberg C, Antoch G, Stegbauer J, et al.
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 2021; (193(6)):658-666 doi:10.1055/a-1299-1878.
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Development of a Prediction Score to Avoid Confirmatory Testing in Patients With Suspected Primary Aldosteronism.
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The Journal of clinical endocrinology and metabolism 2021; (106(4)):e1708-e1716 doi:10.1210/clinem/dgaa974.
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The effect of medication on the aldosterone-to-renin ratio. A critical review of the literature.
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Journal of clinical hypertension (Greenwich, Conn.) 2021; (23(2)):208-214 doi:10.1111/jch.14173.
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Mineralocorticoid Receptor Antagonists Decrease the Rates of Positive Screening for Primary Aldosteronism.
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Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 2020; (26(12)):1416-1424 doi:10.4158/EP-2020-0277.
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ASO Author Reflections: Predicting Postoperative Resolution of Hypertension in Primary Hyperaldosteronism.
Chatani PD, Dominguez DA, Nilubol N
Annals of surgical oncology 2021; (28(12)):7496 doi:10.1245/s10434-021-09762-w.
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Differential effects of reduced mineralocorticoid receptor activation by unilateral adrenalectomy vs mineralocorticoid antagonist treatment in patients with primary aldosteronism - Implications for depression and anxiety.
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Journal of psychiatric research 2021; (137()):376-382 doi:10.1016/j.jpsychires.2021.02.064.
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Functional Characteristic and Significance of Aldosterone-Producing Cell Clusters in Primary Aldosteronism and Age-Related Hypertension.
Pauzi FA, Azizan EA
Frontiers in endocrinology 2021; (12()):631848 doi:10.3389/fendo.2021.631848.
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Prospective Screening for Primary Aldosteronism in Patients With Suspected Obstructive Sleep Apnea.
Chee MR, Hoo J, Libianto R, et al.
Hypertension (Dallas, Tex. : 1979) 2021; (77(6)):2094-2103 doi:10.1161/HYPERTENSIONAHA.120.16902.
PMID: 33896193 - 53
Pathology of Aldosterone Biosynthesis and its Action.
Gao X, Yamazaki Y, Tezuka Y, et al.
The Tohoku journal of experimental medicine 2021; (254(1)):1-15 doi:10.1620/tjem.254.1.
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Re-evaluating absent clinical success after adrenalectomy in unilateral primary aldosteronism.
Chan YHB, Loh LM, Foo RS, et al.
Surgery 2021; (170(5)):1389-1396 doi:10.1016/j.surg.2021.05.038.
PMID: 34183182 - 55
Primary Aldosteronism: a Continuum from Normotension to Hypertension.
Wannachalee T, Turcu AF
Current cardiology reports 2021; (23(8)):105 doi:10.1007/s11886-021-01538-8.
PMID: 34196827 - 56
Improvement in quality of life and psychological symptoms after treatment for primary aldosteronism: Asian Cohort Study.
Tan YK, Kwan YH, Teo DCL, et al.
Endocrine connections 2021; (10(8)):834-844.
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Screening for Primary Aldosteronism is Underutilized in Patients with Obstructive Sleep Apnea.
Conroy PC, Hernandez S, Graves CE, et al.
The American journal of medicine 2022; (135(1)):60-66 doi:10.1016/j.amjmed.2021.07.041.
PMID: 34508708 - 58
The Effects of Verapamil, Hydralazine, and Doxazosin on Renin, Aldosterone, and the Ratio Thereof.
Veldhuizen GP, Alnazer RM, de Leeuw PW, Kroon AA
Cardiovascular drugs and therapy 2023; (37(2)):283-289 doi:10.1007/s10557-021-07262-3.
PMID: 34515895 - 59
Diagnosis and treatment of primary aldosteronism.
Reincke M, Bancos I, Mulatero P, et al.
The lancet. Diabetes & endocrinology 2021; (9(12)):876-892 doi:10.1016/S2213-8587(21)00210-2.
PMID: 34798068 - 60
Screening for primary aldosteronism in the diabetic population: a cohort study.
Tan SJ, Libianto R, Yang J, Wong J
Internal medicine journal 2023; (53(5)):709-716 doi:10.1111/imj.15690.
PMID: 35000250 - 61
Cerebro-Cardiovascular Risk, Target Organ Damage, and Treatment Outcomes in Primary Aldosteronism.
Lin X, Ullah MHE, Wu X, et al.
Frontiers in cardiovascular medicine 2021; (8()):798364 doi:10.3389/fcvm.2021.798364.
PMID: 35187110 - 62
Screening for primary aldosteronism is underutilised in patients with chronic kidney disease.
Chauhan K, Schachna E, Libianto R, et al.
Journal of nephrology 2022; (35(6)):1667-1677 doi:10.1007/s40620-022-01267-3.
PMID: 35195879 - 63
Re-Assessment of the Oral Salt Loading Test Using a New Chemiluminescent Enzyme Immunoassay Based on a Two-Step Sandwich Method to Measure 24-Hour Urine Aldosterone Excretion.
Ozeki Y, Kinoshita M, Miyamoto S, et al.
Frontiers in endocrinology 2022; (13()):859347 doi:10.3389/fendo.2022.859347.
PMID: 35388294 - 64
Japan Endocrine Society clinical practice guideline for the diagnosis and management of primary aldosteronism 2021.
Naruse M, Katabami T, Shibata H, et al.
Endocrine journal 2022; (69(4)):327-359 doi:10.1507/endocrj.EJ21-0508.
PMID: 35418526 - 65
Cardiac Structure and Function Across the Spectrum of Aldosteronism: the Atherosclerosis Risk in Communities Study.
Brown JM, Wijkman MO, Claggett BL, et al.
Hypertension (Dallas, Tex. : 1979) 2022; (79(9)):1984-1993 doi:10.1161/HYPERTENSIONAHA.122.19134.
PMID: 35582954 - 66
Performance of Confirmatory Tests for Diagnosing Primary Aldosteronism: a Systematic Review and Meta-Analysis.
Leung AA, Symonds CJ, Hundemer GL, et al.
Hypertension (Dallas, Tex. : 1979) 2022; (79(8)):1835-1844 doi:10.1161/HYPERTENSIONAHA.122.19377.
PMID: 35652330 - 67
Prevalence and clinical characteristics of primary aldosteronism in a tertiary-care center in Korea.
Yoon M, Hong N, Ha J, et al.
Hypertension research : official journal of the Japanese Society of Hypertension 2022; (45(9)):1418-1429 doi:10.1038/s41440-022-00948-7.
PMID: 35681044 - 68
Aldosterone as a Mediator of Cardiovascular Damage.
Buffolo F, Tetti M, Mulatero P, Monticone S
Hypertension (Dallas, Tex. : 1979) 2022; (79(9)):1899-1911 doi:10.1161/HYPERTENSIONAHA.122.17964.
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Primary Aldosteronism: State-of-the-Art Review.
Vaidya A, Hundemer GL, Nanba K, et al.
American journal of hypertension 2022; (35(12)):967-988 doi:10.1093/ajh/hpac079.
PMID: 35767459 - 70
Development and validation of model for sparing adrenal venous sampling in diagnosing unilateral primary aldosteronism.
Song Y, Yang J, Shen H, et al.
Journal of hypertension 2022; (40(9)):1692-1701 doi:10.1097/HJH.0000000000003197.
PMID: 35881462 - 71
Primary aldosteronism - a multidimensional syndrome.
Turcu AF, Yang J, Vaidya A
Nature reviews. Endocrinology 2022; (18(11)):665-682 doi:10.1038/s41574-022-00730-2.
PMID: 36045149 - 72
Stroke Risks in Primary Aldosteronism with Different Treatments: A Systematic Review and Meta-Analysis.
Qian N, Xu J, Wang Y
Journal of cardiovascular development and disease 2022; (9(9)) doi:10.3390/jcdd9090300.
PMID: 36135445 - 73
Differential central regulatory mineralocorticoidreceptor systems for anxiety and depression - Could KCNJ5 be an interesting target for further investigations in major depression?
Adolf C, Murck H, Sarkis AL, et al.
Journal of psychiatric research 2022; (156()):69-77 doi:10.1016/j.jpsychires.2022.09.008.
PMID: 36242946 - 74
Results from a phase 1, randomized, double-blind, multiple ascending dose study characterizing the pharmacokinetics and demonstrating the safety and selectivity of the aldosterone synthase inhibitor baxdrostat in healthy volunteers.
Freeman MW, Bond M, Murphy B, et al.
Hypertension research : official journal of the Japanese Society of Hypertension 2023; (46(1)):108-118 doi:10.1038/s41440-022-01070-4.
PMID: 36266539 - 75
Cardiovascular outcomes and all-cause mortality in primary aldosteronism after adrenalectomy or mineralocorticoid receptor antagonist treatment: a meta-analysis.
Chen SY, Chen JY, Huang WC, et al.
European journal of endocrinology 2022; (187(6)):S47-S58 doi:10.1530/EJE-22-0375.
PMID: 36315466 - 76
Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension.
Freeman MW, Halvorsen YD, Marshall W, et al.
The New England journal of medicine 2023; (388(5)):395-405 doi:10.1056/NEJMoa2213169.
PMID: 36342143 - 77
Markers of Kidney Tubular Function Deteriorate While Those of Kidney Tubule Health Improve in Primary Aldosteronism After Targeted Treatments.
Wu VC, Chan CK, Chueh JS, et al.
Journal of the American Heart Association 2023; (12(4)):e028146 doi:10.1161/JAHA.122.028146.
PMID: 36789834 - 78
The Adrenal Vein Sampling Outcomes Study (AVOS): success rates following adrenalectomy for unilateral primary aldosteronism.
Sawyer N, Glendenning P, Vasikaran SD, et al.
Pathology 2023; (55(4)):531-537 doi:10.1016/j.pathol.2023.02.002.
PMID: 37062662 - 79
Aldosterone: Essential for Life but Damaging to the Vascular Endothelium.
Crompton M, Skinner LJ, Satchell SC, Butler MJ
Biomolecules 2023; (13(6)) doi:10.3390/biom13061004.
PMID: 37371584 - 80
Using plasma aldosterone concentrations at 1 h of saline infusion test for the diagnosis of primary aldosteronism.
Phonanuwong R, Jannoo S, Chanthanuwat S, Soonthornpun S
Journal of hypertension 2023; (41(9)):1493-1497 doi:10.1097/HJH.0000000000003504.
PMID: 37432888 - 81
Association of Reversal of Renin Suppression With Long-Term Renal Outcome in Medically Treated Primary Aldosteronism.
Katsuragawa S, Goto A, Shinoda S, et al.
Hypertension (Dallas, Tex. : 1979) 2023; (80(9)):1909-1920 doi:10.1161/HYPERTENSIONAHA.123.21096.
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The Value of Targeting CXCR4 With 68Ga-Pentixafor PET/CT for Subtyping Primary Aldosteronism.
Zheng Y, Long T, Peng N, et al.
The Journal of clinical endocrinology and metabolism 2023; (109(1)):171-182 doi:10.1210/clinem/dgad421.
PMID: 37477496 - 83
Renoprotective Effects of Mineralocorticoid Receptor Antagonists Against Diabetic Kidney Disease.
Bayne S, LeFevre J, Olstinske K, et al.
Advanced biology 2024; (8(3)):e2300496 doi:10.1002/adbi.202300496.
PMID: 38065929 - 84
Reversal of arterial stiffness in medically and surgically treated unilateral primary aldosteronism.
Chen ZW, Liao CW, Pan CT, et al.
Journal of hypertension 2024; (42(3)):538-545 doi:10.1097/HJH.0000000000003631.
PMID: 38088428 - 85
Clinical and biochemical outcomes after adrenalectomy for primary aldosteronism in tertiary and quaternary referral centers: data from SOPRANO study.
Marzano L, Ronco C
Hypertension research : official journal of the Japanese Society of Hypertension 2024; (47(3)):721-734 doi:10.1038/s41440-023-01554-x.
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Update on Primary Aldosteronism: Time to Screen All Hypertensives.
Memon SS, Bandgar T
The Journal of the Association of Physicians of India 2024; (72(1)):11-12 doi:10.59556/japi.71.0430.
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Sparing confirmatory testing in primary aldosteronism (SCIPA): a multicenter retrospective diagnostic accuracy study.
Ong Lopez AMC, Tiu LE, Dimayuga DC, et al.
BMC endocrine disorders 2024; (24(1)):105 doi:10.1186/s12902-024-01638-w.
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Comparing ARR Versus Suppressed PRA as Screening Tests for Primary Aldosteronism.
Marcelli M, Bi C, Funder JW, McPhaul MJ
Hypertension (Dallas, Tex. : 1979) 2024; (81(10)):2072-2081 doi:10.1161/HYPERTENSIONAHA.124.22884.
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Impact of primary aldosteronism on kidney function: results from the SPAIN-ALDO registry.
Araujo-Castro M, Paja Fano M, González-Boillos M, et al.
Journal of hypertension 2024; (42(10)):1805-1812 doi:10.1097/HJH.0000000000003813.
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Primary aldosteronism prevalence enhanced by strict adherence to 2016 Endocrine Society guidelines: insights from an endocrine hypertension unit.
Ruiz-Sanchez JG, Fernandez Sanchez Á, Cardenas-Salas J, et al.
Journal of hypertension 2024; (42(10)):1813-1822 doi:10.1097/HJH.0000000000003822.
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