Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
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Harvard University
Cambridge, United States
Université Paris-Est Créteil
Créteil, France
McMaster University
Hamilton, Canada
University of Pennsylvania
Philadelphia, United States
Cornell University
Ithaca, United States
Imperial College London
London, United Kingdom
Inserm
Paris, France
CHU Dijon Bourgogne
Dijon, France
Columbia University Irving Medical Center
New York, United States
Children's Hospital of Philadelphia
Philadelphia, United States
References
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[TREATMENT OF IMMUNE THROMBOCYTOPENIC PURPURA IN ADULTS: UPDATE].
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Cardiovascular and bleeding outcomes in a population-based cohort of patients with chronic immune thrombocytopenia.
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Impact of risk factors on the occurrence of arterial thrombosis and venous thromboembolism in adults with primary immune thrombocytopenia - Results from two nationwide cohorts.
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Appropriateness of intravenous immunoglobulin use in immune thrombocytopenia (ITP): A Canadian centre deep dive audit.
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An update on pathogenesis and diagnosis of thrombotic thrombocytopenic purpura.
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Updated international consensus report on the investigation and management of primary immune thrombocytopenia.
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Thrombopoietin receptor agonists for the treatment of primary immune thrombocytopenia: a meta-analysis and systematic review.
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Evolution and Utility of Antiplatelet Autoantibody Testing in Patients with Immune Thrombocytopenia.
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Romiplostim in adults with newly diagnosed or persistent immune thrombocytopenia.
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Expert review of hematology 2020; (13(12)):1319-1332 doi:10.1080/17474086.2020.1850253.
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Plexus Slim®-Induced Immune Thrombocytopenic Purpura.
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Cureus 2020; (12(11)):e11413 doi:10.7759/cureus.11413.
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Primary immune thrombocytopenia in adults: Belgian recommendations for diagnosis and treatment anno 2021 made by the Belgian Hematology Society.
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Acta clinica Belgica 2022; (77(2)):470-483 doi:10.1080/17843286.2021.1876310.
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Update on diagnosis and treatment of immune thrombocytopenia.
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Expert review of clinical pharmacology 2021; (14(5)):553-568 doi:10.1080/17512433.2021.1903315.
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How I treat primary ITP in adult patients who are unresponsive to or dependent on corticosteroid treatment.
Ghanima W, Gernsheimer T, Kuter DJ
Blood 2021; (137(20)):2736-2744 doi:10.1182/blood.2021010968.
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Assessment of thrombotic risk during long-term treatment of immune thrombocytopenia with fostamatinib.
Cooper N, Altomare I, Thomas MR, et al.
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Exacerbation of immune thrombocytopenia following COVID-19 vaccination.
Kuter DJ
British journal of haematology 2021; (195(3)):365-370 doi:10.1111/bjh.17645.
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Immune Thrombocytopenia: Recent Advances in Pathogenesis and Treatments.
Audia S, Mahévas M, Nivet M, et al.
HemaSphere 2021; (5(6)):e574 doi:10.1097/HS9.0000000000000574.
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A meta-analysis of neonatal outcomes in pregnant women with immune thrombocytopenic purpura.
Luo H, Li D, Gao F, et al.
The journal of obstetrics and gynaecology research 2021; (47(9)):2941-2953 doi:10.1111/jog.14890.
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Romiplostim in children with newly diagnosed or persistent primary immune thrombocytopenia.
Grainger JD, Kühne T, Hippenmeyer J, Cooper N
Annals of hematology 2021; (100(9)):2143-2154 doi:10.1007/s00277-021-04590-0.
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Definition of a critical bleed in patients with immune thrombocytopenia: Communication from the ISTH SSC Subcommittee on Platelet Immunology.
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Journal of thrombosis and haemostasis : JTH 2021; (19(8)):2082-2088 doi:10.1111/jth.15368.
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Risk factors of hospitalisation for thrombosis in adults with primary immune thrombocytopenia, including disease-specific treatments: a French nationwide cohort study.
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British journal of haematology 2021; (195(3)):456-465 doi:10.1111/bjh.17709.
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Corticosteroid overuse in adults with immune thrombocytopenia: Cause for concern.
Cuker A, Liebman HA
Research and practice in thrombosis and haemostasis 2021; (5(6)):e12592 doi:10.1002/rth2.12592.
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SARS-CoV-2 vaccination and ITP in patients with de novo or preexisting ITP.
Lee EJ, Beltrami-Moreira M, Al-Samkari H, et al.
Blood 2022; (139(10)):1564-1574 doi:10.1182/blood.2021013411.
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Consensus guidelines for the management of adult immune thrombocytopenia in Australia and New Zealand.
Choi PY, Merriman E, Bennett A, et al.
The Medical journal of Australia 2022; (216(1)):43-52 doi:10.5694/mja2.51284.
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Splenectomy for primary immune thrombocytopenia revisited in the era of thrombopoietin receptor agonists: New insights for an old treatment.
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American journal of hematology 2022; (97(1)):10-17 doi:10.1002/ajh.26378.
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COVID-19 vaccination in patients with immune thrombocytopenia.
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Blood advances 2022; (6(6)):1637-1644 doi:10.1182/bloodadvances.2021006379.
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Vaccination-associated immune thrombocytopenia possibly due to ChAdOx1 nCoV-19 (Covishield) coronavirus vaccine.
Sivaramakrishnan P, Mishra M
BMJ case reports 2022; (15(3)) doi:10.1136/bcr-2022-249237.
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An updated evaluation of avatrombopag for the treatment of chronic immune thrombocytopenia.
Song AB, Al-Samkari H
Expert review of clinical immunology 2022; (18(8)):783-791 doi:10.1080/1744666X.2022.2098119.
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Primary immune thrombocytopenia: a 'diagnosis of exclusion'?
Visweshwar N, Ayala I, Jaglal M, et al.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2022; (33(6)):289-294 doi:10.1097/MBC.0000000000001144.
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Current approaches for the diagnosis and management of immune thrombocytopenia.
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European journal of internal medicine 2023; (108()):18-24 doi:10.1016/j.ejim.2022.11.022.
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Utilization of an ITP quality improvement pathway improves adherence to management guidelines.
Harris EM, Hillier K, Nolan M, et al.
Pediatric blood & cancer 2023; (70(3)):e30074 doi:10.1002/pbc.30074.
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Advances in management of pediatric chronic immune thrombocytopenia: a narrative review.
Lee JM
Journal of Yeungnam medical science 2023; (40(3)):241-246 doi:10.12701/jyms.2022.00745.
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The role of CD8+ T-cell clones in immune thrombocytopenia.
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Blood 2023; (141(20)):2417-2429 doi:10.1182/blood.2022018380.
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Reticulated Platelet Count as a Diagnostic Tool in Immune Thrombocytopenia (ITP).
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Cureus 2023; (15(7)):e41346 doi:10.7759/cureus.41346.
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Characteristics and outcomes of COVID-19 in Chinese immune thrombocytopenia patients: A prospective cohort study.
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British journal of haematology 2024; (204(4)):1207-1218 doi:10.1111/bjh.19198.
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Concomitant presentation of thrombotic thrombocytopenic purpura, immune thrombocytopenia, and autoimmune hemolytic anemia in a patient with newly diagnosed systemic lupus erythematosus.
Bruns L, Völker L, Klamroth R, et al.
Clinical nephrology. Case studies 2023; (11()):147-153 doi:10.5414/CNCS111193.
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Immune attack on megakaryocytes in immune thrombocytopenia.
Petito E, Gresele P
Research and practice in thrombosis and haemostasis 2024; (8(1)):102345 doi:10.1016/j.rpth.2024.102345.
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The evolution of preexisting primary immune thrombocytopenia after COVID-19 onset: A nationally representative, prospective, multicentre, observational study.
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Annals of hematology 2024; (103(5)):1549-1559 doi:10.1007/s00277-024-05720-0.
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Acquired Amegakaryocytic Thrombocytopenia Misdiagnosed as Immune Thrombocytopenia in a Patient with Seronegative Arthritis: A Case Report.
Arvind MN, Rajanna AH, Kamath N
The Journal of the Association of Physicians of India 2023; (71(11)):100-102 doi:10.59556/japi.71.0386.
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Is it possible to predict morbidities in neonates born to mothers with immune thrombocytopenic purpura?: A retrospective cross-sectional study.
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Medicine 2024; (103(25)):e38587 doi:10.1097/MD.0000000000038587.
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Epidemiology, Treatment Patterns, and Cost Analysis of Immune Thrombocytopenia in Spain between 2014 and 2020: A Population-based Study.
González-López TJ, Alperovich G, Burillo E, et al.
TH open : companion journal to thrombosis and haemostasis 2024; (8(3)):e252-e265 doi:10.1055/a-2336-1062.
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Immune thrombocytopenia and pregnancy: challenges and opportunities in diagnosis and management.
Beltrami-Moreira M, Sharma A, Bussel JB
Expert review of hematology 2024; (17(9)):595-607 doi:10.1080/17474086.2024.2385481.
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The immune thrombocytopenia paradox: Should we be concerned about thrombosis in ITP?
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Thrombosis research 2024; (241()):109109 doi:10.1016/j.thromres.2024.109109.
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[Rinsho ketsueki] The Japanese journal of clinical hematology 2024; (65(9)):1209-1215 doi:10.11406/rinketsu.65.1209.
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Immune Thrombocytopenic Purpura and Maternal and Neonatal Outcomes During Pregnancy: A Systematic Review and Meta-Analysis.
Zhang H, Shi L, Shang H, Yang H
American journal of reproductive immunology (New York, N.Y. : 1989) 2024; (92(5)):e70008 doi:10.1111/aji.70008.
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The Effect of COVID-19 on Platelet Counts in Persistent and Chronic Adult ITP Patients: A Real-World Study in China.
Zhang Y, Yang L, Xu Z, Zhou X
EJHaem 2025; (6(2)):e70025 doi:10.1002/jha2.70025.
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Critical bleeding in adults and children with immune thrombocytopenia: a multicenter cohort study.
Sirotich E, Chowdhury SR, Modi D, et al.
Blood advances 2025; (9(13)):3238-3248 doi:10.1182/bloodadvances.2024015494.
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Refractory Immune Thrombocytopenic Purpura With Low Immature Platelet Fraction.
Ali K, Scotto T, Williams JM, Reddy P
Cureus 2025; (17(4)):e82533 doi:10.7759/cureus.82533.
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Natural killer cell granule protein 7 contributes to CD8+ T cell-mediated platelet apoptosis in immune thrombocytopenia.
Wang X, Liu Q, Li X, et al.
Research and practice in thrombosis and haemostasis 2025; (9(5)):102977 doi:10.1016/j.rpth.2025.102977.
PMID: 40837024 - 88
Treatment options for immune thrombocytopenia (ITP) in pregnancy and postpartum.
Merz LE, Fogerty AE
Expert opinion on pharmacotherapy 2025; (26(13)):1441-1449 doi:10.1080/14656566.2025.2557448.
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A Case of Cerebral Venous Sinus Thrombosis Following Eltrombopag in Immune Thrombocytopenia.
Raja T, Jesiah N, Mayurathan P, Kugathasan A
Cureus 2025; (17(11)):e96811 doi:10.7759/cureus.96811.
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Influence of Anxiety Level and Degree of Alexithymia on Quality of Life in Adult Patients With Primary Immune Thrombocytopenia.
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Actas espanolas de psiquiatria 2025; (53(6)):1274-1285 doi:10.62641/aep.v53i6.2026.
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Incidence, Characteristics, and Management of Venous Thrombosis in Adult Patients With Immune Thrombocytopenia: Results From the Multicenter, Prospective Registry CARMEN-France.
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American journal of hematology 2026; (101(3)):456-466 doi:10.1002/ajh.70192.
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Multicenter initiative to standardize management of pediatric immune thrombocytopenia improves adherence to guidelines.
Gunn E, Angulo PA, Badawy SM, et al.
Blood advances 2026; (10(9)):3304-3312 doi:10.1182/bloodadvances.2025018690.
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A Clinician Perspective for a Personalized Approach to Management of Chronic Immune Thrombocytopenia with Targeted Therapies Alone or in Combination.
Mingot-Castellano ME, Lambert MP, Bowhay-Carnes E
Journal of clinical medicine 2026; (15(4)) doi:10.3390/jcm15041625.
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Risk of thrombosis in adults with primary immune thrombocytopenia treated with eltrombopag vs romiplostim: a target trial emulation in the French Adult Immune Thrombocytopenia (FAITH) cohort.
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Journal of thrombosis and haemostasis : JTH 2026; (24(7)):2567-2578 doi:10.1016/j.jtha.2026.04.002.
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Primary Versus Secondary Immune Thrombocytopenia in Adults: A Comparative Analysis of Clinical and Laboratory Parameters in Newly Diagnosed ITP Patients from North India.
Sandal R, Jandial A, Mishra K, et al.
Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion 2026; (42(4)):1302-1311 doi:10.1007/s12288-025-02119-3.
PMID: 42333197 - 96
Diagnosing Immune Thrombocytopenia: An Update.
Cooper N, Sachs UJ
Hamostaseologie 2026; doi:10.1055/a-2926-8391.
PMID: 42660536