Research & Literature

Premature awakening and underuse of neuromuscular monitoring in a registry of patients with butyrylcholinesterase deficiency.

Thomsen JL, Nielsen CV, Palmqvist DF, Gätke MR

British journal of anaesthesia 2015; (115 Suppl 1()):i89-i94 doi:10.1093/bja/aev103.

New Insights into Butyrylcholinesterase Activity Assay: Serum Dilution Factor as a Crucial Parameter.

Jońca J, Żuk M, Wasąg B, et al.

PloS one 2015; (10(10)):e0139480 doi:10.1371/journal.pone.0139480.

Human butyrylcholinesterase polymorphism: Molecular modeling.

Lushchekina S, Delacour H, Lockridge O, Masson P

The International journal of risk & safety in medicine 2015; (27 Suppl 1()):S80-1 doi:10.3233/JRS-150699.

[Prolonged neuromuscular block in a patient with butyrylcholinesterase deficiency].

Mabboux I, Hary B, Courcelle S, et al.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 2016; (23(5)):497-500.

Butyrylcholinesterase deficiency.

Delacour H, Dedome E, Courcelle S, et al.

Annales de biologie clinique 2016; (74(3)):279-85 doi:10.1684/abc.2016.1141.

A Case of Pseudocholinesterase Deficiency Resulting From Malnutrition.

LaRocca CJ, Beilman GJ, Birch M

A & A case reports 2016; (7(5)):112-4 doi:10.1213/XAA.0000000000000362.

Naturally Occurring Genetic Variants of Human Acetylcholinesterase and Butyrylcholinesterase and Their Potential Impact on the Risk of Toxicity from Cholinesterase Inhibitors.

Lockridge O, Norgren RB, Johnson RC, Blake TA

Chemical research in toxicology 2016; (29(9)):1381-92 doi:10.1021/acs.chemrestox.6b00228.

Delayed recovery from paralysis associated with plasma cholinesterase deficiency.

Zhou W, Lv S

SpringerPlus 2016; (5(1)):1887 doi:10.1186/s40064-016-3561-y.

Resequencing array for gene variant detection in malignant hyperthermia and butyrylcholinestherase deficiency.

Levano S, Gonzalez A, Singer M, et al.

Neuromuscular disorders : NMD 2017; (27(5)):492-499 doi:10.1016/j.nmd.2017.02.008.

Comparison between succinylcholine and rocuronium as neuromuscular blocking agents for electroconvulsive therapy in a patient with pseudocholinesterase deficiency.

Takazawa T, Suto T, Aihara M, et al.

JA clinical reports 2015; (1(1)):7 doi:10.1186/s40981-015-0009-2.

Molecular characterization and polymorphisms of butyrylcholinesterase in cynomolgus macaques.

Uno Y, Uehara S, Mahadhi HMD, et al.

Journal of medical primatology 2018; (47(3)):185-191 doi:10.1111/jmp.12342.

Effects of repetitive prolonged breath-hold in elite divers on myocardial fibrosis and cerebral morphology.

Doerner J, Eichhorn L, Luetkens JA, et al.

European journal of radiology 2018; (103()):13-18 doi:10.1016/j.ejrad.2018.03.020.

Prolonged neuromuscular block associated with cholinesterase deficiency.

Zhang C, Cao H, Wan ZG, Wang J

Medicine 2018; (97(52)):e13714 doi:10.1097/MD.0000000000013714.

Butyrylcholinesterase deficiency and its clinical importance in anaesthesia: a systematic review.

Andersson ML, Møller AM, Wildgaard K

Anaesthesia 2019; (74(4)):518-528 doi:10.1111/anae.14545.

Pseudocholinesterase Deficiency Considerations: A Case Study.

Cornelius BW, Jacobs TM

Anesthesia progress 2020; (67(3)):177-184 doi:10.2344/anpr-67-03-16.

Timing of blood sampling for butyrylcholinesterase phenotyping in patients with prolonged neuromuscular block after mivacurium or suxamethonium.

Mintjens N, Brummans R, Soetens F, et al.

Acta anaesthesiologica Scandinavica 2021; (65(2)):182-187 doi:10.1111/aas.13718.

Genetic Testing for BCHE Variants Identifies Patients at Risk of Prolonged Neuromuscular Blockade in Response to Succinylcholine.

Zhu GD, Dawson E, Huskey A, et al.

Pharmacogenomics and personalized medicine 2020; (13()):405-414 doi:10.2147/PGPM.S263741.

Structure and therapeutic uses of butyrylcholinesterase: Application in detoxification, Alzheimer's disease, and fat metabolism.

Xing S, Li Q, Xiong B, et al.

Medicinal research reviews 2021; (41(2)):858-901 doi:10.1002/med.21745.

Pseudocholinesterase Deficiency - Is Succinylcholine Still Needed to Facilitate Endotracheal Intubation?

Kurnutala LN, Rugnath N

Cureus 2020; (12(9)):e10721 doi:10.7759/cureus.10721.

Isolation, structural characterization and quality control strategy of an unknown process-related impurity in sugammadex sodium.

Zhuang T, Chen Y, Xu J, et al.

Journal of pharmaceutical and biomedical analysis 2021; (200()):114072 doi:10.1016/j.jpba.2021.114072.

Unanticipated Profound Paralysis and Sugammadex Dosing Implications After Videoscopic Thoracic Surgery.

McKittrick ML, Lombard FW

Seminars in cardiothoracic and vascular anesthesia 2022; (26(1)):86-89 doi:10.1177/10892532211059885.

A Comparison of Midazolam and Propofol for Deep Sedation in Patients with Acute Respiratory Distress Syndrome Requiring Neuromuscular Blocking Agents.

Addison JD, Daley MJ, Curran M, Hodge EK

Journal of pharmacy practice 2024; (37(2)):271-278 doi:10.1177/08971900221131420.

Pseudocholinesterase deficiency in ophthalmology: a systematic review.

Cheng T, Curley M, Barmettler A

Orbit (Amsterdam, Netherlands) 2024; (43(3)):429-437 doi:10.1080/01676830.2023.2166083.

Neuromuscular Blockade Monitoring: Having It but Knowing When Not to Trust It.

Salvador S, Frada R, Campos M, Esteves S

Cureus 2023; (15(9)):e45438 doi:10.7759/cureus.45438.

The First-Known Case of Hereditary Heterozygous Butyrylcholinesterase Deficiency in a Patient on Dialysis.

Tokunaga N, Shima H, Okamoto T, et al.

Cureus 2024; (16(1)):e53153 doi:10.7759/cureus.53153.

Suspected Pseudocholinesterase Deficiency During Left Thyroid Lobectomy and Isthmusectomy: A Case Report.

Boleyn J, McLaury M, Wieman S

South Dakota medicine : the journal of the South Dakota State Medical Association 2024; (77(6)):266-269.

Early Neurophysiological Monitoring of Train of Four Assists in the Detection of Pseudocholinesterase Deficiency.

Celis V, Gandhi S, Overzet K

The Neurodiagnostic journal 2025; (65(1)):57-63 doi:10.1080/21646821.2024.2401641.

A novel BCHE frameshift mutation in a Chinese woman with butyrylcholinesterase deficiency: A case report and literature review.

Zeng J, Yang D, Dai T, et al.

Medicine 2024; (103(40)):e39976 doi:10.1097/MD.0000000000039976.

Prolonged Neuromuscular Blockade Following Succinylcholine Administration and the Clinical Importance of Family History: A Case Report.

Hubbell G, Slomowitz S, Thornton I

Cureus 2025; (17(2)):e78814 doi:10.7759/cureus.78814.

Hereditary pseudocholinesterase deficiency in a 4-year-old girl: a case report.

Schulze-Berge J, Pillong L, Busse B, et al.

Journal of medical case reports 2025; (19(1)):145 doi:10.1186/s13256-025-05183-5.

Treatment of acute organophosphate poisoning by using a cocaine hydrolase engineered from human butyrylcholinesterase.

LeSaint JE, Hou S, Chandar NB, et al.

Chemico-biological interactions 2025; (416()):111552 doi:10.1016/j.cbi.2025.111552.

Hereditary Pseudocholinesterase Deficiency and Succinylcholine: Historical Perspective, Therapeutic Implications, and Future Considerations.

Nguyen JQ, Paetznick C, Donnelly RS

Pharmacotherapy 2025; (45(9)):600-620 doi:10.1002/phar.70048.

Prolonged paralysis following mivacurium administration in a pediatric patient with previously undiagnosed pseudocholinesterase deficiency: a case report.

Uzun DD, Wildenberg K, Ruping F, et al.

BMC pediatrics 2025; (25(1)):619 doi:10.1186/s12887-025-05996-9.

Pseudocholinesterase Deficiency Uncovered During Electroconvulsive Therapy: Implications for Psychiatric Services.

Naik MJ, Nirale A, Bhat I, et al.

The journal of ECT 2025; doi:10.1097/YCT.0000000000001177.

Genetic Pseudocholinesterase Deficiency Unmasked After Succinylcholine-Rivastigmine Interaction: A Case Report.

Ho E, Simpson B, Smith NA, Harper S

A&A practice 2025; (19(9)):e02062 doi:10.1213/XAA.0000000000002062.

Pseudocholinesterase Deficiency in a Patient Undergoing Electroconvulsive Therapy: A Case Report.

Ladeira AC, Laranjeira J, Guariento L, et al.

Cureus 2025; (17(12)):e98333 doi:10.7759/cureus.98333.

Genotype-phenotype relationships in butyrylcholinesterase deficiency: a systematic review.

Snak de Souza CD, Ibarra Moreno CA, Riazi S, Hopkins PM

British journal of anaesthesia 2026; (137(2)):450-459 doi:10.1016/j.bja.2026.03.056.

Anesthetic Management of Eosinophilic Granulomatosis with Polyangiitis: A Narrative Review with an Illustrative Case in Cardiac Surgery.

Torre DE, Pirri C

Journal of personalized medicine 2026; (16(5)) doi:10.3390/jpm16050241.