Research & Literature

Incidence and mortality of relapsing polychondritis in the UK: a population-based cohort study.

Hazra N, Dregan A, Charlton J, et al.

Rheumatology (Oxford, England) 2015; (54(12)):2181-7 doi:10.1093/rheumatology/kev240.

Relapsing Polychondritis: an Update on Pathogenesis, Clinical Features, Diagnostic Tools, and Therapeutic Perspectives.

Vitale A, Sota J, Rigante D, et al.

Current rheumatology reports 2016; (18(1)):3 doi:10.1007/s11926-015-0549-5.

Relapsing polychondritis: A clinical update.

Longo L, Greco A, Rea A, et al.

Autoimmunity reviews 2016; (15(6)):539-43.

Scleritis associated with relapsing polychondritis.

Sainz-de-la-Maza M, Molina N, Gonzalez-Gonzalez LA, et al.

The British journal of ophthalmology 2016; (100(9)):1290-4 doi:10.1136/bjophthalmol-2015-306902.

Relapsing Polychondritis Can Be Characterized by Three Different Clinical Phenotypes: Analysis of a Recent Series of 142 Patients.

Dion J, Costedoat-Chalumeau N, Sène D, et al.

Arthritis & rheumatology (Hoboken, N.J.) 2016; (68(12)):2992-3001 doi:10.1002/art.39790.

Relapsing polychondritis: A 2016 update on clinical features, diagnostic tools, treatment and biological drug use.

Mathian A, Miyara M, Cohen-Aubart F, et al.

Best practice & research. Clinical rheumatology 2016; (30(2)):316-333 doi:10.1016/j.berh.2016.08.001.

Aortic involvement in relapsing polychondritis.

Le Besnerais M, Arnaud L, Boutémy J, et al.

Joint bone spine 2018; (85(3)):345-351 doi:10.1016/j.jbspin.2017.05.009.

Efficacy of tocilizumab highlighted by FDG-PET/CT in a patient with relapsing polychondritis-associated aortitis.

Elourimi G, Soussan M, Warzocha U, et al.

Rheumatology international 2017; (37(11)):1931-1935 doi:10.1007/s00296-017-3832-0.

Patient Perception of Disease-Related Symptoms and Complications in Relapsing Polychondritis.

Ferrada MA, Grayson PC, Banerjee S, et al.

Arthritis care & research 2018; (70(8)):1124-1131 doi:10.1002/acr.23492.

Surgical interventions for late ocular complications of relapsing polychondritis.

He Y, Liu H, Ji Z, Zhu B

American journal of ophthalmology case reports 2017; (5()):63-66 doi:10.1016/j.ajoc.2016.12.007.

Efficacy and safety of biologics in relapsing polychondritis: a French national multicentre study.

Moulis G, Pugnet G, Costedoat-Chalumeau N, et al.

Annals of the rheumatic diseases 2018; (77(8)):1172-1178 doi:10.1136/annrheumdis-2017-212705.

Indications and Long-term Outcomes of Open Augmentation Rhinoplasty with Autogenous L-shaped Costal Cartilage Strut Grafts - A Single Plastic Surgeon's Experience.

Leach L, Shamil E, Malata CM

Otolaryngologia polska = The Polish otolaryngology 2018; (72(3)):26-32 doi:10.5604/01.3001.0011.7258.

Relapsing Polychondritis: An Updated Review.

Borgia F, Giuffrida R, Guarneri F, Cannavò SP

Biomedicines 2018; (6(3)) doi:10.3390/biomedicines6030084.

Observational study and brief analysis of diagnostic criteria in relapsing polychondritis.

Rose T, Schneider U, Bertolo M, et al.

Rheumatology international 2018; (38(11)):2095-2101 doi:10.1007/s00296-018-4121-2.

Clinical Characteristics of Relapsing Polychondritis: A Report of 8 Cases in Japan.

Tajiri M, Tominaga M, Kinoshita T, et al.

The Kurume medical journal 2019; (65(2)):47-53 doi:10.2739/kurumemedj.MS652006.

Long-Term Outcome of Metallic Stenting for Central Airway Involvement in Relapsing Polychondritis.

Wu X, Zhang X, Zhang W, et al.

The Annals of thoracic surgery 2019; (108(3)):897-904 doi:10.1016/j.athoracsur.2019.02.039.

Concomitant aortic valve replacement, mitral valve replacement, and coronary artery bypass grafting for aortic stenosis and mitral regurgitation in a patient with relapsing polychondritis.

Kisamori E, Otani S, Yamamoto T, et al.

General thoracic and cardiovascular surgery 2020; (68(2)):185-189 doi:10.1007/s11748-019-01130-6.

Patient-perceived Burden of Disease in Pediatric Relapsing Polychondritis.

Rimland CA, Ferrada MA, Sinaii N, et al.

The Journal of rheumatology 2019; (46(12)):1627-1633 doi:10.3899/jrheum.181456.

Fluorodeoxyglucose positron emission tomography/computed tomography in the diagnosis, assessment of disease activity and therapeutic response in relapsing polychondritis.

Sharma A, Kumar R, Mb A, et al.

Rheumatology (Oxford, England) 2020; (59(1)):99-106 doi:10.1093/rheumatology/kez243.

Tracheobronchial involvement of relapsing polychondritis.

de Montmollin N, Dusser D, Lorut C, et al.

Autoimmunity reviews 2019; (18(9)):102353 doi:10.1016/j.autrev.2019.102353.

Reconstructive rhinoplasty with costal cartilage grafting: A case report of relapsing polychondritis.

Lee Y, Choi H

Archives of craniofacial surgery 2019; (20(5)):341-344 doi:10.7181/acfs.2019.00437.

Aortic involvement in relapsing polychondritis: case-based review.

Erdogan M, Esatoglu SN, Hatemi G, Hamuryudan V

Rheumatology international 2021; (41(4)):827-837 doi:10.1007/s00296-019-04468-5.

Is 18F-FDG PET/CT useful for diagnosing relapsing polychondritis with airway involvement and monitoring response to steroid-based therapy?

Zeng Y, Li M, Chen S, et al.

Arthritis research & therapy 2019; (21(1)):282 doi:10.1186/s13075-019-2083-8.

Large-vessel Vasculitis Affecting the Aorta and its Branches in Relapsing Polychondritis: Case Series and Systematic Review of the Literature.

Tomelleri A, Campochiaro C, Sartorelli S, et al.

The Journal of rheumatology 2020; (47(12)):1780-1784 doi:10.3899/jrheum.190862.

A case of localized tracheobronchial relapsing polychondritis with positive matrilin-1 staining.

Makiguchi T, Koarai A, Inoue C, et al.

BMC rheumatology 2020; (4()):1 doi:10.1186/s41927-019-0103-6.

Diagnosing relapsing polychondritis remains a common challenge: experience from a Chinese retrospective cohort.

Zhang L, Wu TG, He YJ, et al.

Clinical rheumatology 2020; (39(7)):2179-2184 doi:10.1007/s10067-019-04852-3.

Relapsing polychondritis, a rare cause of valvulopathy: a review of the medical literature.

Bahena-López E, Loya-Centurión J

Archivos de cardiologia de Mexico 2020; (90(2)):189-192 doi:10.24875/ACM.19000245.

Sustained Remission with Tocilizumab in Refractory Relapsing Polychondritis with Ocular Involvement: A Case Series.

Farhat R, Clavel G, Villeneuve D, et al.

Ocular immunology and inflammation 2021; (29(1)):9-13 doi:10.1080/09273948.2020.1763405.

[Auricular chondritis as first symptom of ANCA-associated vasculitis].

Pfannkuch L, Schneider U, Rudolph B, et al.

Zeitschrift fur Rheumatologie 2020; (79(9)):902-905 doi:10.1007/s00393-020-00841-z.

[Diagnosis and treatment of laryngotracheal stenosis induced by relapsing polychondritis].

Guo Z, Zhao D, Xing Y, et al.

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery 2020; (34(6)):524-527 doi:10.13201/j.issn.2096-7993.2020.06.011.

Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease.

Beck DB, Ferrada MA, Sikora KA, et al.

The New England journal of medicine 2020; (383(27)):2628-2638 doi:10.1056/NEJMoa2026834.

Development and Validation of a Simplified Probability Assessment Score Integrated With Age-Adjusted d-Dimer for Diagnosis of Acute Aortic Syndromes.

Morello F, Bima P, Pivetta E, et al.

Journal of the American Heart Association 2021; (10(3)):e018425 doi:10.1161/JAHA.120.018425.

Respiratory subtype of relapsing polychondritis frequently presents as difficult asthma: a descriptive study of respiratory involvement in relapsing polychondritis with 13 patients from a single UK centre.

Dubey S, Gelder C, Pink G, et al.

ERJ open research 2021; (7(1)) doi:10.1183/23120541.00170-2020.

Somatic Mutations in UBA1 Define a Distinct Subset of Relapsing Polychondritis Patients With VEXAS.

Ferrada MA, Sikora KA, Luo Y, et al.

Arthritis & rheumatology (Hoboken, N.J.) 2021; (73(10)):1886-1895 doi:10.1002/art.41743.

Sudden Sensorineural Hearing and Vestibular Loss in a Case of Relapsing Polychondritis.

Akdoğan Ö, Exilus S, Ward BK, et al.

The Annals of otology, rhinology, and laryngology 2021; (130(12)):1412-1416 doi:10.1177/00034894211005979.

Three new inflammatory markers C reactive protein to albumin ratio, neutrophil to lymphocyte ratio, and platelet to lymphocyte ratio correlated with relapsing polychondritis disease activity index.

Cao X, Zhao M, Li H, et al.

Clinical rheumatology 2021; (40(11)):4685-4691 doi:10.1007/s10067-021-05827-z.

Characteristics and Clinical Outcomes of 295 Patients With Relapsing Polychondritis.

Chen N, Zheng Y

The Journal of rheumatology 2021; (48(12)):1876-1882 doi:10.3899/jrheum.210062.

[Rapid Growing Thoracic Aortic Aneurysm in a Patient with Relapsing Polychondritis].

Yamamoto T, Adachi K, Hori D, et al.

Kyobu geka. The Japanese journal of thoracic surgery 2021; (74(8)):583-586.

Case of paediatric relapsing polychondritis with severe airway involvement: the challenges of long-term airway and respiratory management.

Kothari T, Valsamakis T, Sridhar AV, Ahmed MI

BMJ case reports 2021; (14(8)) doi:10.1136/bcr-2020-239774.

Discordance in patient and physician global assessment in relapsing polychondritis.

Rose E, Ferrada MA, Quinn KA, et al.

Rheumatology (Oxford, England) 2022; (61(5)):2025-2033 doi:10.1093/rheumatology/keab587.

Unusual Presentation of Relapsing Polychondritis in a Patient with Human Immunodeficiency Virus and Reactive Arthritis.

Alfraji N, Alpert DR

The American journal of case reports 2021; (22()):e933327 doi:10.12659/AJCR.933327.

Bronchoscopy-Guided Intervention Therapy With Extracorporeal Membrane Oxygenation Support for Relapsing Polychondritis With Severe Tracheobronchomalacia: A Case Report and Literature Review.

Zhou P, Fu B, Zhang C, et al.

Frontiers in medicine 2021; (8()):695505 doi:10.3389/fmed.2021.695505.

Biologic therapy in relapsing polychondritis: navigating between options.

Padoan R, Campaniello D, Iorio L, et al.

Expert opinion on biological therapy 2022; (22(5)):661-671 doi:10.1080/14712598.2022.2048647.

Treatment of relapsing polychondritis: a systematic review.

Petitdemange A, Sztejkowski C, Damian L, et al.

Clinical and experimental rheumatology 2022; (40 Suppl 134(5)):81-85 doi:10.55563/clinexprheumatol/h9gq1o.

Relapsing Polychondritis and Aseptic Meningoencephalitis.

Yokota K, Tachibana H, Miyake A, et al.

Internal medicine (Tokyo, Japan) 2023; (62(3)):481-486 doi:10.2169/internalmedicine.9411-22.

Comparison between idiopathic and VEXAS-relapsing polychondritis: analysis of a French case series of 95 patients.

Khitri MY, Guedon AF, Georgin-Lavialle S, et al.

RMD open 2022; (8(2)) doi:10.1136/rmdopen-2022-002255.

Differentiating tracheobronchial involvement in granulomatosis with polyangiitis and relapsing polychondritis on chest CT: a cohort study.

Jalaber C, Puéchal X, Saab I, et al.

Arthritis research & therapy 2022; (24(1)):241 doi:10.1186/s13075-022-02935-2.

Reconstructive rhinoplasty using cadaver cartilage in relapsing polychondritis.

Shah R, Alford EL

Proceedings (Baylor University. Medical Center) 2023; (36(1)):130-131 doi:10.1080/08998280.2022.2114067.

Respiratory Failure during BIS-Guided Sedation in a Patient with Relapsing Polychondritis: A Case Report.

Lee J, Moon H, Hong S, et al.

Medicina (Kaunas, Lithuania) 2022; (59(1)) doi:10.3390/medicina59010065.

VEXAS: where do we stand 2 years later?

Sujobert P, Heiblig M, Jamilloux Y

Current opinion in hematology 2023; (30(2)):64-69 doi:10.1097/MOH.0000000000000750.

The ocular manifestations of relapsing polychondritis.

Gallagher K, Al-Janabi A, Wang A

International ophthalmology 2023; (43(8)):2633-2641 doi:10.1007/s10792-023-02662-w.

Evaluation of airway involvement and treatment in patients with relapsing polychondritis.

Handa H, Ooka S, Shimizu J, et al.

Scientific reports 2023; (13(1)):8307 doi:10.1038/s41598-023-35616-4.

French practical guidelines for the diagnosis and management of relapsing polychondritis.

Arnaud L, Costedoat-Chalumeau N, Mathian A, et al.

La Revue de medecine interne 2023; (44(6)):282-294 doi:10.1016/j.revmed.2023.05.005.

Relapsing polychondritis in systemic sclerosis: A rare vasculitic mimic.

Teles C, Liyanage CK, Chow G, et al.

Journal of scleroderma and related disorders 2023; (8(2)):NP4-NP8 doi:10.1177/23971983221141599.

Relapsing polychondritis: focus on cardiac involvement.

Yin R, Zhao M, Xu D, et al.

Frontiers in immunology 2023; (14()):1218475 doi:10.3389/fimmu.2023.1218475.

Imaging features and clinical value of 18F-FDG PET/CT for predicting airway involvement in patients with relapsing polychondritis.

Yi JW, Huang JF, Hou P, et al.

Arthritis research & therapy 2023; (25(1)):198 doi:10.1186/s13075-023-03156-x.

Development and validation of diagnostic and activity-assessing models for relapsing polychondritis based on laboratory parameters.

Liu Y, Cheng L, Zhao M, et al.

Frontiers in immunology 2023; (14()):1274677 doi:10.3389/fimmu.2023.1274677.

Venous and arterial thrombosis in patients with VEXAS syndrome.

Kusne Y, Ghorbanzadeh A, Dulau-Florea A, et al.

Blood 2024; (143(21)):2190-2200 doi:10.1182/blood.2023022329.

VEXAS syndrome: An update.

Khitri MY, Hadjadj J, Mekinian A, Jachiet V

Joint bone spine 2024; (91(4)):105700 doi:10.1016/j.jbspin.2024.105700.

Risk factors associated with severe adverse events in patients with relapsing polychondritis undergoing flexible bronchoscopy.

Wang ST, Wang J, Gao X, et al.

Orphanet journal of rare diseases 2024; (19(1)):54 doi:10.1186/s13023-024-03061-9.

Autoimmunity and Autoinflammation: Relapsing Polychondritis and VEXAS Syndrome Challenge.

Cardoneanu A, Rezus II, Burlui AM, et al.

International journal of molecular sciences 2024; (25(4)) doi:10.3390/ijms25042261.

Beyond the Earlobe: Navigating the Complexities of Relapsing Polychondritis.

Jun S, Chang S, Kooner A, et al.

Cureus 2024; (16(2)):e54293 doi:10.7759/cureus.54293.

[Tracheobronchial involvement in relapsing polychondritis and differential diagnoses].

Grandière L, Gille T, Brillet PY, et al.

Revue des maladies respiratoires 2024; (41(6)):421-438 doi:10.1016/j.rmr.2024.03.009.

A Case of Relapsing Polychondritis: Unmasking the Otitis Externa Mimic.

Bandari V, Aguilar BH

Cureus 2024; (16(7)):e64070 doi:10.7759/cureus.64070.

A multicenter study of long-term outcomes of relapsing polychondritis in Iran.

Jafarpour M, Saberivand M, Saemi M, et al.

Scientific reports 2024; (14(1)):16486 doi:10.1038/s41598-024-67530-8.

Comprehensive Interventional treatment for severe central airway collapse caused by Relapsing Polychondritis: A case report.

Wu Y, Wang M, Wang H, et al.

Heliyon 2024; (10(18)):e37680 doi:10.1016/j.heliyon.2024.e37680.

Diagnostic Challenges and Management of Relapsing Polychondritis with Large-Airway Involvement: A Case Series and Literature Review.

Kuo IC, Hsieh CI, Lee YC, et al.

Life (Basel, Switzerland) 2024; (14(9)) doi:10.3390/life14091194.

Relapsing polychondritis in childhood: A case report.

Li P, Chen Z, Lv H, Lin L

Medicine 2024; (103(41)):e40106 doi:10.1097/MD.0000000000040106.

Relapsing polychondritis: tracheobronchial involvement and differential diagnoses.

Grandière L, Vicaire H, Pop G, et al.

Journal of thoracic disease 2025; (17(1)):461-475 doi:10.21037/jtd-24-1603.

Laryngeal involvement in relapsing polychondritis: clinical and CT findings in 173 patients.

Bai X, Yu R, Wang Z

RMD open 2025; (11(2)) doi:10.1136/rmdopen-2024-005397.

Delayed Diagnosis and Outcomes in Acute Aortic Dissection: A 10-Year Single-Center Retrospective Study.

Kanoksirirat S, Nithimathachoke A

Open access emergency medicine : OAEM 2025; (17()):173-183 doi:10.2147/OAEM.S496279.

Clinical diagnosis and treatment of pediatric-onset relapsing polychondritis with airway involvement.

Wang Y, Xie Z, Chen J, Li X

Frontiers in pediatrics 2025; (13()):1548142 doi:10.3389/fped.2025.1548142.

[Treatment of a patient with relapsing polychondritis: Case report].

Reznik EV, Golubev YY, Yurtayeva NV, et al.

Terapevticheskii arkhiv 2025; (97(5)):471-474 doi:10.26442/00403660.2025.05.203212.

Hansen's Disease Presenting as Perichondritis: A Rare ENT Diagnostic Challenge - Case Series.

Bohra V, Banger S, Ravunnikutty M, Goyal S

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India 2025; (77(8)):3312-3317 doi:10.1007/s12070-025-05740-w.

Evaluation of Semicircular Canal Function Using the Video Head Impulse Test in a Case of Relapsing Polychondritis and Otitis Media With Effusion.

Fujiwara K, Morita S, Takeda H, Homma A

Cureus 2025; (17(9)):e92184 doi:10.7759/cureus.92184.

A Case of Relapsing Polychondritis With Severe Obstructive Ventilatory Defect Caused by a Single Flare-Up.

Nakagawa R, Kishimoto A, Namiki T, et al.

Respirology case reports 2025; (13(11)):e70415 doi:10.1002/rcr2.70415.

What are risk factors for relapse in relapsing polychondritis? A retrospective study.

Zhang N, Liu S, Liu Y, et al.

Clinical rheumatology 2026; (45(2)):1155-1164 doi:10.1007/s10067-025-07831-z.

Morphologic Deciphering of Hematopoietic Cell Vacuolization: Lessons From VEXAS Syndrome and Other Etiologies.

Abro B, Deeb G, Asakrah S

International journal of laboratory hematology 2026; (48(3)):561-572 doi:10.1111/ijlh.70056.

Identifying quality of life domains and facets affected in relapsing polychondritis: a qualitative analysis for the development of a disease-specific health-related quality of life instrument.

Mertz P, Sander O, Faria R, et al.

Orphanet journal of rare diseases 2026; (21(1)).

Bimekizumab rescue therapy in a patient with relapsing polychondritis-associated aortitis.

Kremer P, Melderis S, Ruffer N, et al.

EULAR rheumatology open 2025; (1(2)):60-62 doi:10.1016/j.ero.2025.05.005.

Unveiling the clinical and proteomic spectrum of relapsing polychondritis with respiratory involvement.

Fang X, Liao X, Gao W, et al.

Frontiers in immunology 2026; (17()):1866652 doi:10.3389/fimmu.2026.1866652.