Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
Top Authors
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The Kids Research Institute Australia
West Perth, Australia
Cincinnati Children's Hospital Medical Center
Cincinnati, United States
Charles Darwin University
Darwin, Australia
Uganda Management Institute
Kampala, Uganda
Children's National
Washington, United States
South African Medical Research Council
Cape Town, South Africa
University of Cape Town
Rondebosch, South Africa
Royal Children's Hospital
Melbourne, Australia
All India Institute of Medical Sciences
New Delhi, India
Inserm
Paris, France
References
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The personal and clinical impact of screen-detected maternal rheumatic heart disease in Uganda: a prospective follow up study.
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The Medical journal of Australia 2021; (214(5)):220-227 doi:10.5694/mja2.50851.
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Mid-term outcome of children with latent rheumatic heart disease in eastern Nepal.
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Open heart 2021; (8(1)) doi:10.1136/openhrt-2021-001605.
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Bioprosthetic versus mechanical mitral valve replacements in patients with rheumatic heart disease.
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The Journal of thoracic and cardiovascular surgery 2023; (165(3)):1050-1060.e8 doi:10.1016/j.jtcvs.2021.03.033.
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Mitral Valve Surgery in Patients With Rheumatic Heart Disease: Repair vs. Replacement.
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The Canadian journal of cardiology 2021; (37(12)):2045-2055 doi:10.1016/j.cjca.2021.09.015.
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Right Atrial Thrombus in a Patient of Rheumatic Heart Disease with Severe Mitral Regurgitation: A Rare Association.
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Secondary Antibiotic Prophylaxis for Latent Rheumatic Heart Disease.
Beaton A, Okello E, Rwebembera J, et al.
The New England journal of medicine 2022; (386(3)):230-240 doi:10.1056/NEJMoa2102074.
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Prevalence of rheumatic heart disease in adults from the Brazilian Amazon Basin.
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International journal of cardiology 2022; (352()):115-122 doi:10.1016/j.ijcard.2022.01.026.
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Meta-Analysis of Mitral Valve Repair Versus Replacement for Rheumatic Mitral Valve Disease.
Liao YB, Wang TKM, Wang MTM, et al.
Heart, lung & circulation 2022; (31(5)):705-710 doi:10.1016/j.hlc.2021.11.011.
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Medium-term outcomes from mitral valve surgery for rheumatic heart disease in young adults in Aotearoa New Zealand: a cohort study.
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ANZ journal of surgery 2022; (92(5)):1060-1065 doi:10.1111/ans.17685.
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Balloon Mitral Valvotomy With the Accura Double-Lumen Balloon Catheter: Immediate and One-Year Clinical Outcomes.
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Cureus 2022; (14(4)):e24610 doi:10.7759/cureus.24610.
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Bioprosthetic vs. Mechanical Mitral Valve Replacement for Rheumatic Heart Disease in Patients Aged 50-70 Years.
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Frontiers in cardiovascular medicine 2022; (9()):904958 doi:10.3389/fcvm.2022.904958.
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Chronic rheumatic heart disease with recrudescence of acute rheumatic fever on histology: a case report.
Mutithu DW, Roberts R, Manganyi R, Ntusi NAB
European heart journal. Case reports 2022; (6(7)):ytac278 doi:10.1093/ehjcr/ytac278.
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Therapeutics for rheumatic fever and rheumatic heart disease.
Ralph AP, Currie BJ
Australian prescriber 2022; (45(4)):104-112 doi:10.18773/austprescr.2022.034.
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Recommendations for the Use of Echocardiography in the Evaluation of Rheumatic Heart Disease: A Report from the American Society of Echocardiography.
Pandian NG, Kim JK, Arias-Godinez JA, et al.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2023; (36(1)):3-28 doi:10.1016/j.echo.2022.10.009.
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Anticoagulation for rheumatic mitral stenosis, INVICTUS in perspective.
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Current opinion in cardiology 2023; (38(2)):55-60 doi:10.1097/HCO.0000000000001013.
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Demographics and Characteristics of Acutely Decompensated Heart Failure (ADHF) Patients in a Tertiary Care Center in Saudi Arabia.
Alalawi H, Fida HL, Bokhary OA, et al.
Cureus 2023; (15(3)):e35724 doi:10.7759/cureus.35724.
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DOACs and rheumatic valvulopathy: always a red light?
Rochira C, Capodanno D
European heart journal supplements : journal of the European Society of Cardiology 2023; (25(Suppl B)):B41-B45 doi:10.1093/eurheartjsupp/suad065.
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A Retrospective Study on Drug and Dietary Patterns in Patients With Severe Rheumatic Valvular Heart Disease in Eastern India.
Das D, Mohanty S, Guru S, et al.
Cureus 2023; (15(4)):e37358 doi:10.7759/cureus.37358.
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A Rare Case of Congestive Heart Failure due to Isolated Aortic Valve Disease in a Middle-Aged Man Secondary to Rheumatic Fever.
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Journal of medical cases 2023; (14(5)):149-154 doi:10.14740/jmc4090.
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Health Related Quality of Life of Ugandan Children Following Valve Replacement Surgery for Rheumatic Heart Disease.
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Global heart 2023; (18(1)):37 doi:10.5334/gh.1205.
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Pregnancy outcomes in women with heart disease: the Madras Medical College Pregnancy And Cardiac (M-PAC) Registry from India.
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European heart journal 2023; (44(17)):1530-1540 doi:10.1093/eurheartj/ehad003.
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Echocardiography Assessment of Rheumatic Heart Disease: Implications for Percutaneous Balloon Mitral Valvuloplasty.
Mohamed Ali A, Packer EJS, Omdal TR, et al.
Current problems in cardiology 2023; (48(12)):102021 doi:10.1016/j.cpcardiol.2023.102021.
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Pregnancy risk and contraception among reproductive-age women with rheumatic heart disease attending care at a tertiary cardiac center in Tanzania: a hospital-based cross-sectional study.
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BMC women's health 2023; (23(1)):404 doi:10.1186/s12905-023-02332-0.
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Left ventricular remodelling in rheumatic heart disease - trends over time and implications for follow-up in childhood.
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BMC cardiovascular disorders 2023; (23(1)):462 doi:10.1186/s12872-023-03497-0.
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Transcatheter heart valve interventions for patients with rheumatic heart disease.
Weich H, Herbst P, Smit F, Doubell A
Frontiers in cardiovascular medicine 2023; (10()):1234165 doi:10.3389/fcvm.2023.1234165.
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Myocardial infarction due to septic thromboembolism in chronic rheumatic heart disease.
Rachagiri S, Sekar A, Mehrotra S, Saikia UN
Autopsy & case reports 2023; (13()):e2023444 doi:10.4322/acr.2023.444.
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The Aswan Rheumatic heart disease reGIstry: rationale and preliminary results of the ARGI database.
Kotit S, Yacoub MH
Frontiers in cardiovascular medicine 2023; (10()):1230965 doi:10.3389/fcvm.2023.1230965.
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2023 World Heart Federation guidelines for the echocardiographic diagnosis of rheumatic heart disease.
Rwebembera J, Marangou J, Mwita JC, et al.
Nature reviews. Cardiology 2024; (21(4)):250-263 doi:10.1038/s41569-023-00940-9.
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Subcutaneous infusion of high-dose benzathine penicillin G is safe, tolerable, and suitable for less-frequent dosing for rheumatic heart disease secondary prophylaxis: a phase 1 open-label population pharmacokinetic study.
Kado J, Salman S, Hla TK, et al.
Antimicrobial agents and chemotherapy 2023; (67(12)):e0096223 doi:10.1128/aac.00962-23.
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Coronary artery disease in patients with rheumatic valvular heart disease- An analysis from eastern India.
Karak A, Deb N, Khanra D, et al.
Indian heart journal 2024; (76(1)):48-50 doi:10.1016/j.ihj.2023.11.268.
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Imaging for the assessment of the arrhythmogenic potential of mitral valve prolapse.
Esposito A, Gatti M, Trivieri MG, et al.
European radiology 2024; (34(7)):4243-4260 doi:10.1007/s00330-023-10413-9.
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The Echocardiographic Diagnosis of Rheumatic Heart Disease: A Review of the Performance of the World Heart Federation Criteria 2012-2023.
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Global heart 2024; (19(1)):47 doi:10.5334/gh.1327.
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Patient preferences for prophylactic regimens requiring regular injections in children and adolescents: a systematic review and thematic analysis.
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BMJ paediatrics open 2024; (8(1)) doi:10.1136/bmjpo-2023-002450.
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Intramuscular versus enteral penicillin prophylaxis to prevent progression of rheumatic heart disease: Study protocol for a noninferiority randomized trial (the GOALIE trial).
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American heart journal 2024; (275()):74-85 doi:10.1016/j.ahj.2024.05.012.
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Sydenham's chorea in a 16-year-old female from Bhutan: A case report.
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Clinical case reports 2024; (12(7)):e9047 doi:10.1002/ccr3.9047.
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Clinical outcome of patients with rheumatic tricuspid valve disease: matched cohort study.
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The international journal of cardiovascular imaging 2024; (40(9)):1911-1918 doi:10.1007/s10554-024-03180-1.
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Impact of Tricuspid Repair on Surgical Death in Patients Undergoing Mitral Valve Surgery Due to Rheumatic Disease.
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Structural heart : the journal of the Heart Team 2024; (8(4)):100298 doi:10.1016/j.shj.2024.100298.
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Prevalence and associated factors of atrial fibrillation among patients with rheumatic heart disease attending public referral hospitals in Bahir Dar city, Northwest Ethiopia, 2023.
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BMC cardiovascular disorders 2024; (24(1)):434 doi:10.1186/s12872-024-04092-7.
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Local anaesthetic to reduce injection pain in patients who are prescribed intramuscular benzathine penicillin G: a systematic review and meta-analysis.
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EClinicalMedicine 2024; (76()):102817 doi:10.1016/j.eclinm.2024.102817.
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Long-term antibiotic prophylaxis for prevention of rheumatic fever recurrence and progression to rheumatic heart disease.
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The Cochrane database of systematic reviews 2024; (9()):CD015779 doi:10.1002/14651858.CD015779.
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Rheumatic heart disease manifesting as mitral stenosis and tricuspid regurgitation in a young Asian male: a case report.
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Association Between the Expression of T Helper Type 17 Cell-Related Cytokines and Valve Damage in Rheumatic Heart Disease.
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Global, Regional, and National Burden of Valvular Heart Disease, 1990 to 2021.
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Journal of the American Heart Association 2024; (13(24)):e037991 doi:10.1161/JAHA.124.037991.
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Inhibition of Endothelial-Mesenchymal Transition Mediated by Activin Receptor Type IIA Attenuates Valvular Injury Induced by Group A Streptococcus in Lewis Rats.
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Enhanced support for adherence to rheumatic heart disease prophylaxis for children in the public health system in Uganda (CAMPS): a pragmatic randomised trial.
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Rheumatic Valvulopathy in Sub-Saharan Africa: A Cross-Sectional Study of Cameroonian Urban Schools.
Nganou-Gnindjio CN, Ladibe AG, Nyaga JMO, et al.
Global heart 2025; (20(1)):36 doi:10.5334/gh.1414.
PMID: 40161864 - 95
Upstream and Downstream Cardiovascular Changes in Rheumatic Mitral Stenosis: An Update.
Rudiktyo E, Teske AJ, Yonas E, et al.
Journal of clinical medicine 2025; (14(8)) doi:10.3390/jcm14082639.
PMID: 40283468 - 96
Using Shockwave Lithotripsy to Treat Severe Calcified Mitral Stenosis in a Pregnant Woman.
Habib MB, Aboulmaaly CA, Mohammed N, Al-Hijji M
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 2025; (106(2)):1062-1066 doi:10.1002/ccd.31641.
PMID: 40457582 - 97
A 17-Year Experience of Valvular Heart Surgery in Rwanda.
Musoni M, Wang S, Schulick N, et al.
The Annals of thoracic surgery 2026; (121(2)):393-400 doi:10.1016/j.athoracsur.2025.06.008.
PMID: 40550320 - 98
Inflammatory Responses Potentiate GAS M Protein Induced Cardiac Damage in an Experimental Model of Rheumatic Heart Disease.
Rafeek RAM, Reynolds SL, Pandey M, et al.
Immunity, inflammation and disease 2025; (13(7)):e70221 doi:10.1002/iid3.70221.
PMID: 40642941 - 99
The Impact of Acute Rheumatic Fever Diagnosis on Rheumatic Heart Disease Severity.
Williamson JM, Whalley G, Thornley S, et al.
Global heart 2025; (20(1)):72 doi:10.5334/gh.1454.
PMID: 40894083 - 100
The economic burden of rheumatic heart disease in the Eastern Mediterranean Region.
Elmusharaf K, Poix S, Scaria EB, et al.
BMJ global health 2025; (10(10)) doi:10.1136/bmjgh-2024-018277.
PMID: 41062128 - 101
Predominant Rheumatic Tricuspid Stenosis.
Alizadeh L, Vainrib AF, Ro R, et al.
JACC. Case reports 2025; (30(33)):104808 doi:10.1016/j.jaccas.2025.104808.
PMID: 41136055 - 102
Sepsis in the Structurally-Vulnerable Heart: A Case of Infective Endocarditis Masquerading as a Urinary Tract Infection in Pediatric Rheumatic Heart Disease.
Mikami A, Sherwood M, Nassar A, et al.
Cureus 2025; (17(10)):e94673 doi:10.7759/cureus.94673.
PMID: 41257102 - 103
Rapid screening for acute rheumatic fever using machine learning analysis of host tissue reactive antibodies.
Vo B, Rafeek RAM, Surve NZ, et al.
Scientific reports 2025; (15(1)):41316 doi:10.1038/s41598-025-25171-5.
PMID: 41271880 - 104
Stroke as First Presentation of Rheumatic Heart Disease in Pediatric Age Group - a Case Report from Developing Country, Rwanda.
Desta TT, Peace MK, Kayihura J
Pediatric health, medicine and therapeutics 2025; (16()):307-311 doi:10.2147/PHMT.S553619.
PMID: 41287844 - 105
Atrial fibrillation-induced severe left ventricular dysfunction postmitral valve replacement in an adolescent with rheumatic mitral regurgitation.
Chawla R, Shrivastava Y, Gupta A, Duggal B
BMJ case reports 2026; (19(2)) doi:10.1136/bcr-2025-267313.
PMID: 41734963 - 106
Valve biology and rheumatic heart disease pathogenesis.
Yeow S, Frost H, Porrello ER, et al.
Nature cardiovascular research 2026; (5(3)):204-217 doi:10.1038/s44161-026-00792-9.
PMID: 41807679 - 107
Early rheumatic heart disease is a recognized intermediate on the pathway to advanced rheumatic heart disease.
Marangou J, Wirth SH, Zühlke L, et al.
International journal of cardiology 2026; (453()):134432 doi:10.1016/j.ijcard.2026.134432.
PMID: 41833866 - 108
Rheumatic heart disease is not over: Cardiac cirrhosis and multivalvular sequelae in an endemic setting - A case series and review.
Sethi Y, Yadav ND, Singhal S, et al.
Current problems in cardiology 2026; (51(7)):103329 doi:10.1016/j.cpcardiol.2026.103329.
PMID: 41864251 - 109
Percutaneous mitral balloon commissurotomy in juvenile rheumatic mitral stenosis patients: a ten-year experience from Ethiopia.
Sebah MB, Mengistu AD, Alene TD, et al.
BMC cardiovascular disorders 2026; (26(1)).
PMID: 41877032 - 110
Myocarditis Following Invasive Group A Streptococcus Infection: Important Differential Diagnostic Distinctions.
Oxman JM, Bourne M, Perlman DC, Sells N
Case reports in infectious diseases 2026; (2026()):5349221 doi:10.1155/crdi/5349221.
PMID: 41953693 - 111
Rheumatic mitral valve disease: Comparative outcomes of repair versus replacement.
Araujo S, Silva H, Filho R, et al.
Global cardiology science & practice 2025; (2025(6)):e202560 doi:10.21542/gcsp.2025.60.
PMID: 41978891 - 112
Digoxin in Patients With Symptomatic Rheumatic Heart Disease: A Randomized Clinical Trial.
Karthikeyan G, Devasenapathy N, Ghosh A, et al.
JAMA 2026; (335(23)):2020-2028 doi:10.1001/jama.2026.7335.
PMID: 42106990