Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
Top Authors
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University of Cape Town
Rondebosch, South Africa
South African Medical Research Council
Cape Town, South Africa
Uganda Management Institute
Kampala, Uganda
Eduardo Mondlane University
Maputo, Mozambique
Invictus Medical (United States)
San Antonio, United States
Jimma University
Jimma, Ethiopia
Translational Health Science and Technology Institute
Gurugram, India
University Teaching Hospital
Lusaka, Zambia
University of Indonesia
Depok, Indonesia
Alzaiem Alazhari University
Khartoum, Sudan
References
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The Role of Stress Echocardiography in Valvular Heart Disease: A Current Appraisal.
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Management of tricuspid valve regurgitation: Position statement of the European Society of Cardiology Working Groups of Cardiovascular Surgery and Valvular Heart Disease.
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European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2017; (52(6)):1022-1030 doi:10.1093/ejcts/ezx279.
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Features of rheumatic mitral valves and a grading system to identify suitable repair cases in China.
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Transcatheter aortic valve replacement in patients with degenerative calcified rheumatic aortic stenosis: A 10-patient case series.
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International journal of cardiology 2019; (280()):38-42 doi:10.1016/j.ijcard.2018.11.090.
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How Many Doses Make a Difference? An Analysis of Secondary Prevention of Rheumatic Fever and Rheumatic Heart Disease.
de Dassel JL, de Klerk N, Carapetis JR, Ralph AP
Journal of the American Heart Association 2018; (7(24)):e010223 doi:10.1161/JAHA.118.010223.
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Prevalence, risk determinants and consequences of atrial fibrillation in rheumatic heart disease: 6 years hospital based-Himachal Pradesh- Rheumatic Fever/Rheumatic Heart Disease (HP-RF/RHD) Registry.
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Long-Term Outcomes After Mitral Valve Replacement and Tricuspid Annuloplasty in Rheumatic Patients.
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Treatment of Hypertensive Cardiogenic Edema with Intravenous High-Dose Nitroglycerin in a Patient Presenting with Signs of Respiratory Failure: A Case Report and Review of the Literature.
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Mitral Stenosis in Pregnancy: A Comprehensive Review of a Challenging Cardio-Obstetric Clinical Entity.
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Molecular Mimicry, Autoimmunity, and Infection: The Cross-Reactive Antigens of Group A Streptococci and their Sequelae.
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Can Direct Oral Anticoagulants Be Used for Stroke Prevention Among Patients with Valvular Atrial Fibrillation?
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Prevalence and Factors Associated with Atrial Fibrillation Among Patients with Rheumatic Heart Disease.
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The INVICTUS rheumatic heart disease research program: Rationale, design and baseline characteristics of a randomized trial of rivaroxaban compared to vitamin K antagonists in rheumatic valvular disease and atrial fibrillation.
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Prediction of adverse cardiac events in pregnant women with valvular rheumatic heart disease.
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Heart (British Cardiac Society) 2020; (106(18)):1400-1406 doi:10.1136/heartjnl-2020-316648.
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Mitral valve repair versus replacement in patients with rheumatic heart disease.
Chen SW, Chen CY, Chien-Chia Wu V, et al.
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CT for Pre- and Postprocedural Evaluation of Transcatheter Mitral Valve Replacement.
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Contemporary Diagnosis and Management of Rheumatic Heart Disease: Implications for Closing the Gap: A Scientific Statement From the American Heart Association.
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Clinical, Echocardiographic Characteristics and Management Practices in Patients with Rheumatic Valvular Heart Disease.
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Advances in Rheumatic Mitral Stenosis: Echocardiographic, Pathophysiologic, and Hemodynamic Considerations.
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Universal Definition and Classification of Heart Failure.
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Impact of concomitant tricuspid annuloplasty on right ventricular remodeling in patients with rheumatic mitral valve disease.
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Bioprosthetic versus mechanical mitral valve replacements in patients with rheumatic heart disease.
Chen CY, Chan YH, Wu VC, et al.
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A longitudinal study of antibody responses to selected host antigens in rheumatic fever and rheumatic heart disease.
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Transcatheter Aortic Valve Replacement in Rheumatic Aortic Stenosis: A Comprehensive Review.
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The assessment of mitral valve disease: a guideline from the British Society of Echocardiography.
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Admission systolic blood pressure as a prognostic predictor of acute decompensated heart failure: A report from the KCHF registry.
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Non-infectious thrombotic endocarditis associated with chronic rheumatic heart disease and disseminated tuberculosis.
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Autopsy & case reports 2021; (11()):e2021269 doi:10.4322/acr.2021.269.
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Patterns of Rheumatic Heart Disease and Treatment Practices at Tertiary Care Center in Nepal: A Descriptive Cross-sectional Study.
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Right Atrial Thrombus in a Patient of Rheumatic Heart Disease with Severe Mitral Regurgitation: A Rare Association.
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Trans-esophageal Echocardiographic Assessment of Left Atrial and Left Atrial Appendage Function in Atrial Fibrillation and Rheumatic Heart Disease.
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Increased Breadth of Group A Streptococcus Antibody Responses in Children With Acute Rheumatic Fever Compared to Precursor Pharyngitis and Skin Infections.
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The Journal of infectious diseases 2022; (226(1)):167-176 doi:10.1093/infdis/jiac043.
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[Percutaneous dilation of mitral stenosis in patients with severe pulmonary hypertension during pregnancy].
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Data-independent acquisition mass spectrometry in severe rheumatic heart disease (RHD) identifies a proteomic signature showing ongoing inflammation and effectively classifying RHD cases.
Salie MT, Yang J, Ramírez Medina CR, et al.
Clinical proteomics 2022; (19(1)):7 doi:10.1186/s12014-022-09345-1.
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Acute Rheumatic Fever and Rheumatic Heart Disease: Highlighting the Role of Group A Streptococcus in the Global Burden of Cardiovascular Disease.
Auala T, Zavale BG, Mbakwem AÇ, Mocumbi AO
Pathogens (Basel, Switzerland) 2022; (11(5)) doi:10.3390/pathogens11050496.
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Chronic rheumatic heart disease with recrudescence of acute rheumatic fever on histology: a case report.
Mutithu DW, Roberts R, Manganyi R, Ntusi NAB
European heart journal. Case reports 2022; (6(7)):ytac278 doi:10.1093/ehjcr/ytac278.
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Identification of Distinct Subgroups in Moderately Severe Rheumatic Mitral Stenosis Using Data-Driven Phenotyping of Longitudinal Hemodynamic Progression.
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Journal of the American Heart Association 2022; (11(15)):e026375 doi:10.1161/JAHA.121.026375.
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Recommendations for the Use of Echocardiography in the Evaluation of Rheumatic Heart Disease: A Report from the American Society of Echocardiography.
Pandian NG, Kim JK, Arias-Godinez JA, et al.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2023; (36(1)):3-28 doi:10.1016/j.echo.2022.10.009.
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A study of Clinical Profile and in Hospital Outcomes of patients undergoing Percutaneous Transvenous Mitral Commissurotomy at a Tertiary Care Center of Nepal.
Yadav S, Shah S, Gajurel RM, et al.
Annals of medicine and surgery (2012) 2022; (84()):104867 doi:10.1016/j.amsu.2022.104867.
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Valvular Heart Disease Presenting as Sympathetic Crashing Acute Pulmonary Edema (SCAPE) Phenomenon: A Diagnostic and Management Paradigm.
Ashok H, Shtembari J, Achhami E, et al.
Cureus 2022; (14(12)):e32352 doi:10.7759/cureus.32352.
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Anticoagulation for rheumatic mitral stenosis, INVICTUS in perspective.
Verma R, Latter DA
Current opinion in cardiology 2023; (38(2)):55-60 doi:10.1097/HCO.0000000000001013.
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IgG2 rules: N-acetyl-β-D-glucosamine-specific IgG2 and Th17/Th1 cooperation may promote the pathogenesis of acute rheumatic heart disease and be a biomarker of the autoimmune sequelae of Streptococcus pyogenes.
Kirvan CA, Canini H, Swedo SE, et al.
Frontiers in cardiovascular medicine 2022; (9()):919700 doi:10.3389/fcvm.2022.919700.
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A Rare Case of Congestive Heart Failure due to Isolated Aortic Valve Disease in a Middle-Aged Man Secondary to Rheumatic Fever.
Panduranga VT, Gorantla A, Ahmed A, et al.
Journal of medical cases 2023; (14(5)):149-154 doi:10.14740/jmc4090.
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Acute heart failure and valvular heart disease: A scientific statement of the Heart Failure Association, the Association for Acute CardioVascular Care and the European Association of Percutaneous Cardiovascular Interventions of the European Society of Cardiology.
Chioncel O, Adamo M, Nikolaou M, et al.
European journal of heart failure 2023; (25(7)):1025-1048 doi:10.1002/ejhf.2918.
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Echocardiography Assessment of Rheumatic Heart Disease: Implications for Percutaneous Balloon Mitral Valvuloplasty.
Mohamed Ali A, Packer EJS, Omdal TR, et al.
Current problems in cardiology 2023; (48(12)):102021 doi:10.1016/j.cpcardiol.2023.102021.
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Transcatheter heart valve interventions for patients with rheumatic heart disease.
Weich H, Herbst P, Smit F, Doubell A
Frontiers in cardiovascular medicine 2023; (10()):1234165 doi:10.3389/fcvm.2023.1234165.
PMID: 37771665 - 64
Myocardial infarction due to septic thromboembolism in chronic rheumatic heart disease.
Rachagiri S, Sekar A, Mehrotra S, Saikia UN
Autopsy & case reports 2023; (13()):e2023444 doi:10.4322/acr.2023.444.
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Giant Right Atrium: An Extreme Structural Damage Case Due to Rheumatic Heart Disease.
Voltarelli CL, Olandoski Erbano B, Magalhães T, et al.
Cureus 2023; (15(9)):e44898 doi:10.7759/cureus.44898.
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Effects of mitral valve disease etiology on the outcomes of mechanical and biological valve replacement: retrospective cohort study.
Chen CY, Chang FC, Lin CP, et al.
International journal of surgery (London, England) 2024; (110(6)):3495-3503 doi:10.1097/JS9.0000000000001283.
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Adherence to penicillin treatment is essential for effective secondary prevention of rheumatic heart disease: a systematic review and meta-analysis.
Ambari AM, Radi B, Dwiputra B, et al.
Annals of medicine and surgery (2012) 2024; (86(4)):2116-2123 doi:10.1097/MS9.0000000000001833.
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Echocardiographic Parameters and Complication Profiles Among Adult Patients with Rheumatic Heart Disease at Jimma Medical Center.
Berhanu H, Mossie A, Morankar SN, et al.
Vascular health and risk management 2024; (20()):157-166 doi:10.2147/VHRM.S451957.
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Rheumatic heart disease of the mitral valve alongside the papillary fibroelastoma of the aortic valve: A case report.
Khezerlouy Aghdam N, Delkhah M, Danayi S, Sobhi N
Clinical case reports 2024; (12(5)):e8845 doi:10.1002/ccr3.8845.
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Mortality and Morbidity in Adults With Rheumatic Heart Disease.
Karthikeyan G, Ntsekhe M, Islam S, et al.
JAMA 2024; (332(2)):133-140 doi:10.1001/jama.2024.8258.
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Validation of Yeo's index in assessing severity of rheumatic mitral stenosis in mixed valve lesions.
Leow R, Li TY, Kong WKF, et al.
International journal of cardiology. Heart & vasculature 2024; (53()):101447 doi:10.1016/j.ijcha.2024.101447.
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Long-term antibiotic prophylaxis for prevention of rheumatic fever recurrence and progression to rheumatic heart disease.
Bray JJ, Thompson S, Seitler S, et al.
The Cochrane database of systematic reviews 2024; (9()):CD015779 doi:10.1002/14651858.CD015779.
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Progression of Rheumatic Heart Disease: A Case of Failed Secondary Prevention.
Gan A, Pham V, Fong M, Davar K
JACC. Case reports 2024; (29(20)):102620 doi:10.1016/j.jaccas.2024.102620.
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From the INVICTUS Trial to Current Considerations: It's Not Time to Retire Vitamin K Inhibitors Yet!
Pradhan A, Mahalawat S, Perrone MA
Pharmaceuticals (Basel, Switzerland) 2024; (17(11)) doi:10.3390/ph17111459.
PMID: 39598370 - 75
From Strep Infection to a Strepitous Heart Pattern in Rheumatic Fever: A Case Report.
Machuca JN
Cureus 2024; (16(11)):e72997 doi:10.7759/cureus.72997.
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Prevalence of pulmonary hypertension and associated factors among rheumatic heart disease patients in Ethiopia.
Gedefaw A, Ayele YY, Wudie G, et al.
BMC cardiovascular disorders 2025; (25(1)):20 doi:10.1186/s12872-025-04476-3.
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Upstream and Downstream Cardiovascular Changes in Rheumatic Mitral Stenosis: An Update.
Rudiktyo E, Teske AJ, Yonas E, et al.
Journal of clinical medicine 2025; (14(8)) doi:10.3390/jcm14082639.
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Characteristics and Problems of Rheumatic Heart Disease in Indonesia: The Ina-RHD Multicenter Study.
Soesanto AM, Almazini P, Ariani R, et al.
JACC. Asia 2025; (5(9)):1171-1183 doi:10.1016/j.jacasi.2025.03.010.
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Prevalence and associated factors of atrial fibrillation among acute stroke patients at public referral hospitals in Bahir Dar, Ethiopia, 2024: a cross-sectional study.
Molla E, Ayele YY, Ayenew T, et al.
BMC cardiovascular disorders 2025; (25(1)):424 doi:10.1186/s12872-025-04839-w.
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Rheumatic Valve Disease Presenting As Mitral Stenosis and Regurgitation.
Javed N, Pineda R, Itare V, et al.
Cureus 2025; (17(6)):e86671 doi:10.7759/cureus.86671.
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Society of cardiothoracic surgery in great Britain and Ireland guidance for adult mitral valve disease and interventions.
Vohra HA, Burton S, Yadav R, et al.
BMJ surgery, interventions, & health technologies 2025; (7(1)):e000328 doi:10.1136/bmjsit-2024-000328.
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Chronic Mitral Valve Fibrosis in Rheumatic Heart Disease: From Immune Trigger to Inflammatory and Mechanical Progression.
Liu Z, Liu R, Liang J, et al.
Journal of the American Heart Association 2025; (14(22)):e045169 doi:10.1161/JAHA.125.045169.
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Systemic Soluble and Cellular Immune Response in Acute Rheumatic Fever and Rheumatic Heart Disease: A Systematic Review of Human Studies.
Resende ALDS, Neves EGA, Cavalcante BM, Dutra WO
Pathogens (Basel, Switzerland) 2025; (14(11)) doi:10.3390/pathogens14111185.
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Surgical implications of rheumatic heart disease in Indian females.
Chandra A, Gutti R, Sisodia A, et al.
Indian journal of thoracic and cardiovascular surgery 2026; (42(1)):59-77 doi:10.1007/s12055-025-02068-6.
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Clinical worsening in adult congenital heart disease and heart failure: A single-centre, observational study.
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International journal of cardiology. Congenital heart disease 2026; (23()):100656 doi:10.1016/j.ijcchd.2026.100656.
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Rheumatic heart disease is not over: Cardiac cirrhosis and multivalvular sequelae in an endemic setting - A case series and review.
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Current problems in cardiology 2026; (51(7)):103329 doi:10.1016/j.cpcardiol.2026.103329.
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Survival and mortality predictors among adults with rheumatic heart disease in ethiopia: a 10-year retrospective cohort study.
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BMC cardiovascular disorders 2026; (26(1)).
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Myocarditis Following Invasive Group A Streptococcus Infection: Important Differential Diagnostic Distinctions.
Oxman JM, Bourne M, Perlman DC, Sells N
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Clinical and echocardiographic predictors of reintervention after percutaneous or surgical treatment of rheumatic mitral stenosis: A systematic review.
Gómez-Gualdrón SA, Macias-Martinez JS, Pulido-Parra AM, et al.
Current problems in cardiology 2026; (51(9)):103358 doi:10.1016/j.cpcardiol.2026.103358.
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Mitral Stenosis in the Multimodality Imaging Era: Pitfalls, Stress Echocardiography, and Integrated Therapeutic Assessment.
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