Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
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Emory University
Atlanta, United States
Johns Hopkins University
Baltimore, United States
University of Alabama at Birmingham
Birmingham, United States
Inserm
Paris, France
Boston University
Boston, United States
Cincinnati Children's Hospital Medical Center
Cincinnati, United States
Medical University of South Carolina
Charleston, United States
Children's Hospital of Philadelphia
Philadelphia, United States
Washington University in St. Louis
St Louis, United States
King's College London
London, United Kingdom
References
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A 5-year cost analysis of automated red cell exchange transfusion for the management of recurrent painful crises in adult patients with sickle cell disease.
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Clinical and Ophthalmic Factors Associated With the Severity of Sickle Cell Retinopathy.
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International Differences in Outpatient Pain Management: A Survey of Sickle Cell Disease.
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Journal of clinical medicine 2019; (8(12)) doi:10.3390/jcm8122136.
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Use of an automated pyrosequencing technique for confirmation of sickle cell disease.
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Hydroxyurea Dose Escalation for Sickle Cell Anemia in Sub-Saharan Africa.
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The New England journal of medicine 2020; (382(26)):2524-2533 doi:10.1056/NEJMoa2000146.
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Sickle cell disease in the era of precision medicine: looking to the future.
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Sickle Cell Disease in Jordan: The Experience of a Major Referral Center.
Oudat RI, Abualruz HS, Al-Shiek NKA, et al.
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The Alberta Newborn Screening Approach for Sickle Cell Disease: The Advantages of Molecular Testing.
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International journal of neonatal screening 2021; (7(4)) doi:10.3390/ijns7040078.
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Acute chest syndrome of sickle cell disease: genetics, risk factors, prognosis, and management.
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Expert review of hematology 2022; (15(2)):117-125 doi:10.1080/17474086.2022.2041410.
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Difficulties in the diagnosis of HbS/beta thalassemia: Really a mild disease?
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Journal of medical biochemistry 2022; (41(1)):32-39 doi:10.5937/jomb0-30420.
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Fertility after Curative Therapy for Sickle Cell Disease: A Comprehensive Review to Guide Care.
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Journal of clinical medicine 2022; (11(9)) doi:10.3390/jcm11092318.
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High risk and low prevalence diseases: Acute chest syndrome in sickle cell disease.
Koehl JL, Koyfman A, Hayes BD, Long B
The American journal of emergency medicine 2022; (58()):235-244 doi:10.1016/j.ajem.2022.06.018.
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Value of DNA testing in the diagnosis of sickle-cell anemia in childhood in an environment with a high prevalence of other causes of anemia.
Mbayabo G, Lumbala Kabuyi P, Ngole M, et al.
Journal of clinical laboratory analysis 2022; (36(8)):e24593 doi:10.1002/jcla.24593.
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Parvovirus b19 infection in children with sickle cell disease, watch out for splenomegaly! A case report.
de la Hoz JA, Otones LL, Sáenz MH, Martín MJR
African health sciences 2022; (22(1)):598-601 doi:10.4314/ahs.v22i1.69.
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The prevalence of sickling abnormality in Oman: A review of relevant publications
Al-Mashaikhi N, Al-Rawas A, Wali Y, et al.
Acta bio-medica : Atenei Parmensis 2022; (93(4)):e2022289 doi:10.23750/abm.v93i4.13336.
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Sickle Cell Disease in Children and Adolescents: A Review of the Historical, Clinical, and Public Health Perspective of Sub-Saharan Africa and Beyond.
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International journal of pediatrics 2022; (2022()):3885979 doi:10.1155/2022/3885979.
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The Cardiopulmonary Complications of Sickle Cell Disease.
Desai AA, Machado RF, Cohen RT
Hematology/oncology clinics of North America 2022; (36(6)):1217-1237 doi:10.1016/j.hoc.2022.07.014.
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Expecting more: the case for incorporating fertility services into comprehensive sickle cell disease care.
Pecker LH, Oteng-Ntim E, Nero A, et al.
The Lancet. Haematology 2023; (10(3)):e225-e234 doi:10.1016/S2352-3026(22)00353-2.
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Compound Heterogeneous Sickle Cell-B+ Thalassemia Incidentally Discovered Through Cytological Examination of a Fine-Needle Aspiration Specimen from an Aneurysmal Bone Cyst in a Young Child: A Case Report.
Meliti A, Muftah S, Saleh D, Habibullah N
Cureus 2023; (15(1)):e33594 doi:10.7759/cureus.33594.
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Description of a Colocated Comprehensive Care Model for People With Sickle Cell and Comorbid Pulmonary Disease.
Pugh C, Zeno RN, Stanek J, et al.
Journal of pediatric hematology/oncology 2023; (45(6)):e723-e727 doi:10.1097/MPH.0000000000002655.
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Female Reproductive Health Outcomes after Hematopoietic Cell Transplantation for Sickle Cell Disease: Is Reduced Intensity Better Than Myeloablative Conditioning?
Meacham LR, George S, Veludhandi A, et al.
Transplantation and cellular therapy 2023; (29(8)):531.e1-531.e4 doi:10.1016/j.jtct.2023.05.004.
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Psychosocial challenges of persons with sickle cell anemia: A narrative review.
Essien EA, Winter-Eteng BF, Onukogu CU, et al.
Medicine 2023; (102(47)):e36147 doi:10.1097/MD.0000000000036147.
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Clinical, laboratory, and molecular characteristics of a cohort of children with hemoglobinopathy S/beta-thalassemia.
Oliveira ÉL, Belisário AR, Silva NP, et al.
Hematology, transfusion and cell therapy 2024; (46(2)):167-175 doi:10.1016/j.htct.2023.11.002.
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MALDI-MS in first-line screening of newborns for sickle cell disease: results from a prospective study in comparison to HPLC.
El Osta M, Benoist JF, Naubourg P, et al.
Clinical chemistry and laboratory medicine 2024; (62(6)):1149-1157 doi:10.1515/cclm-2023-1250.
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DISPLACE study shows poor quality of transcranial doppler ultrasound for stroke risk screening in sickle cell anemia.
Davidow KA, Miller RE, Phillips SM, et al.
Blood advances 2024; (8(13)):3444-3452 doi:10.1182/bloodadvances.2024012631.
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Sputum interleukin-6 level as a marker of severity during acute chest syndrome in children with sickle cell disease.
Mayrand L, Elie J, Pinhas Y, et al.
British journal of haematology 2024; (205(1)):329-334 doi:10.1111/bjh.19561.
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Effects of hydroxyurea on fertility in male and female sickle cell disease patients. A systemic review and meta-analysis.
Sewaralthahab S, Alsubki LA, Alhrabi MS, Alsultan A
PloS one 2024; (19(6)):e0304241 doi:10.1371/journal.pone.0304241.
PMID: 38848387 - 75
The German sickle cell disease registry reveals a surprising risk of acute splenic sequestration and an increased transfusion requirement in patients with compound heterozygous sickle cell disease HbS/β-thalassaemia and no or low HbA expression.
Allard P, Tagliaferri L, Weru V, et al.
European journal of haematology 2024; (113(4)):501-509 doi:10.1111/ejh.14259.
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Advances in sickle cell retinopathy screening techniques, tests, and practices: A systematic review.
Cummings OW, Rahman S, Fletcher L, Scott AW
American journal of hematology 2024; (99(11)):2152-2163 doi:10.1002/ajh.27439.
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Diagnostic accuracy of mean corpuscular volume in detecting coexisting iron deficiency in patients of sickle cell disorders: A hospital-based study.
Joshi M, Joshi A
Journal of family medicine and primary care 2024; (13(7)):2647-2652 doi:10.4103/jfmpc.jfmpc_1552_23.
PMID: 39071021 - 78
Distinguishing Iron Deficiency Anemia From Beta-Thalassemia Trait: Comparative Analysis of CRUISE Index and Other Traditional Diagnostic Indices.
Hans A, Atreja CB, Batra N
Cureus 2024; (16(7)):e64048 doi:10.7759/cureus.64048.
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Characterizing medical decision-making in sickle cell disease during childhood: Qualitative perspectives of caregivers.
Blakey AO, Amaro CM, Eilenberg JS, et al.
Pediatric blood & cancer 2024; (71(12)):e31307 doi:10.1002/pbc.31307.
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Prevalence and Predictive Factors of Sickle Cell Emergencies Readmission in the Clinical Hematology Department of Dakar, Senegal.
Diallo AB, Seck M, Touré SA, et al.
Anemia 2024; (2024()):7143716 doi:10.1155/anem/7143716.
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Prevention of Invasive Pneumococcal Disease Among Black or African American Children With and Without Sickle Cell Disease in the United States After Introduction of 13-Valent Pneumococcal Conjugate Vaccine, 2005 Through 2019.
Payne AB, Gierke R, Xing W, et al.
Pediatric blood & cancer 2025; (72(3)):e31467 doi:10.1002/pbc.31467.
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Neurological management of ischemic stroke in sickle cell disease- a case report with an updated review of the literature.
Ciprietti C, Russo M, Santilli M, et al.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2025; (46(2)):993-998 doi:10.1007/s10072-024-07948-0.
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Reproductive functions and fertility preservation in men with sickle cell disease.
Leblanc C, Sermondade N, Rivet-Danon D, et al.
Andrology 2025; (13(8)):2142-2149 doi:10.1111/andr.70021.
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Investigation of Sickle Cell Retinopathy in Pediatric and Adolescent Patients Enrolled in a Large Cohort Study.
Smith BD, Hankins JS, Kang G, et al.
Ophthalmology 2025; (132(8)):911-920 doi:10.1016/j.ophtha.2025.03.031.
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Reproductive Choices in Haemoglobinopathies: The Role of Preimplantation Genetic Testing.
Kakourou G, Vrettou C, Mamas T, Traeger-Synodinos J
Genes 2025; (16(4)) doi:10.3390/genes16040360.
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Position Paper on the Management of Sickle Cell Disease in Saudi Arabia: Understanding Disease Landscape, Identifying Challenges, and Exploring Opportunities in Transfusion Therapies.
AlHumaidan H, Al Zayed A, Al Bahrani A, et al.
Journal of clinical medicine 2025; (14(10)) doi:10.3390/jcm14103494.
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Reproductive function and sperm parameters in men with sickle cell disease: a systematic review.
Leblanc C, Sermondade N, Ogouma-Aworet L, et al.
Asian journal of andrology 2026; (28(2)):117-127 doi:10.4103/aja202510.
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National Alliance of Sickle Cell Centers consensus standards for transition to adult care in sickle cell disease.
Guarino SH, Jain A, Madisetti M, et al.
Blood advances 2025; (9(18)):4585-4591 doi:10.1182/bloodadvances.2025015909.
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Ischemic Stroke as the Initial Presentation of Sickle Beta Thalassemia in an Adolescent: A Case Report.
Sinha S, Sharma J, Arun S, et al.
Cureus 2025; (17(5)):e84254 doi:10.7759/cureus.84254.
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Emergency care for children with sickle cell disease: a focus on pain and fever.
Korman R, Hatabah D, Morris CR
Expert review of hematology 2025; (18(11)):899-921 doi:10.1080/17474086.2025.2538537.
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A Case of Sickle Cell Beta Thalassemia and Recurrent Septicemia.
LeRoy DI, Ognjanovski E, Desai A, et al.
Cureus 2025; (17(7)):e87521 doi:10.7759/cureus.87521.
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Challenges Associated with the Identification of Abnormal Hemoglobin Variants Utilizing the High-performance Liquid Chromatograph Technique: A Prospective Study in a Hospital Setting in Gujarat.
Anandani G, Motiani A, Goswami P, Sonagra A
International journal of applied & basic medical research 2025; (15(3)):197-205 doi:10.4103/ijabmr.ijabmr_70_25.
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Hydroxyurea for Children with Sickle Cell Disease: A Practical Guide for Pediatric Clinicians.
Coyne F, Strouse JJ
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