Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
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The Alfred Hospital
Melbourne, Australia
Monash University
Melbourne, Australia
University of California, San Francisco
San Francisco, United States
The University of Sydney
Sydney, Australia
Inserm
Paris, France
Centers for Disease Control and Prevention
Atlanta, United States
Tel Aviv University
Tel Aviv, Israel
California Department of Public Health
Sacramento, United States
University of California, Los Angeles
Los Angeles, United States
Colorado School of Public Health
Aurora, United States
References
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The 6-Minute Walk Test as a Tool for Determining Exercise Capacity and Prognosis in Patients with Silicosis.
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The Burden of Silicosis in Michigan: 1988-2016.
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Silicosis and lung cancer: current perspectives.
Sato T, Shimosato T, Klinman DM
Lung Cancer (Auckland, N.Z.) 2018; (9()):91-101 doi:10.2147/LCTT.S156376.
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Occupational and environmental medicine 2019; (76(3)):178-180 doi:10.1136/oemed-2018-105462.
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Silicosis With Secondary Spontaneous Pneumothorax in the Western Rajasthan.
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Cureus 2020; (12(11)):e11811 doi:10.7759/cureus.11811.
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Astragaloside IV alleviates silica‑induced pulmonary fibrosis via inactivation of the TGF‑β1/Smad2/3 signaling pathway.
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International journal of molecular medicine 2021; (47(3)).
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Occupational exposure to respirable crystalline silica and risk of autoimmune rheumatic diseases: a nationwide cohort study.
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Mini-review: Silico-tuberculosis.
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Journal of clinical tuberculosis and other mycobacterial diseases 2021; (23()):100218 doi:10.1016/j.jctube.2021.100218.
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Association between Financial Conflicts of Interest and International Labor Office Classifications for Black Lung Disease.
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Annals of the American Thoracic Society 2021; (18(10)):1634-1641 doi:10.1513/AnnalsATS.202010-1350OC.
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Lung transplantation: candidate selection and timing of transplant.
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Current opinion in organ transplantation 2021; (26(3)):302-308 doi:10.1097/MOT.0000000000000879.
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Respirology case reports 2021; (9(6)):e00765 doi:10.1002/rcr2.765.
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The association between silica exposure, silicosis and tuberculosis: a systematic review and meta-analysis.
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Revue des maladies respiratoires 2021; (38(7)):768-772 doi:10.1016/j.rmr.2021.05.001.
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Silicosis, progressive massive fibrosis and silico-tuberculosis among workers with occupational exposure to silica dusts in sandstone mines of Rajasthan state: An urgent need for initiating national silicosis control programme in India.
Nandi SS, Dhatrak SV, Sarkar K
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Pirfenidone ameliorates silica-induced lung inflammation and fibrosis in mice by inhibiting the secretion of interleukin-17A.
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Inter-observer agreement and accuracy in classifying radiographs for pneumoconiosis among Asian physicians taking AIR Pneumo certification examination.
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Dusty trades and associated rheumatoid arthritis in a population-based study in the coal mining counties of Appalachia.
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Occupational and environmental medicine 2022; (79(5)):308-314 doi:10.1136/oemed-2021-107899.
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Respirable Dust and Silica: Respiratory Diseases Among Swedish Iron Foundry Workers.
Lenander-Ramirez A, Bryngelsson IL, Vihlborg P, et al.
Journal of occupational and environmental medicine 2022; (64(7)):593-598 doi:10.1097/JOM.0000000000002533.
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Characterisation of dust emissions from machined engineered stones to understand the hazard for accelerated silicosis.
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Comparison of Silicosis and Tuberculosis Involving Mediastinal Lymph Nodes Based on Contrast-Enhanced Multidetector-Row Computed Tomography.
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Lung 2022; (200(2)):261-268 doi:10.1007/s00408-022-00522-5.
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Volume-based tomography for the diagnosis of incipient silicosis in former gold miners.
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Occupational and environmental medicine 2022; (79(6)):427-432 doi:10.1136/oemed-2021-107922.
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Predictors of psychological stress in silica-exposed workers in the artificial stone benchtop industry.
Hore-Lacy F, Hansen J, Dimitriadis C, et al.
Respirology (Carlton, Vic.) 2022; (27(6)):455-461 doi:10.1111/resp.14257.
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Mechanical Ventilation for COVID-19 Patients.
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Seminars in respiratory and critical care medicine 2022; (43(3)):405-416 doi:10.1055/s-0042-1744305.
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Early Identification, Accurate Diagnosis, and Treatment of Silicosis.
Li T, Yang X, Xu H, Liu H
Canadian respiratory journal 2022; (2022()):3769134 doi:10.1155/2022/3769134.
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The Effectiveness of Whole Lung Lavage in Pneumoconiosis: A Systematic Review and Meta-Analysis.
Zeng Y, Jiang Y, Banks DE
Journal of occupational and environmental medicine 2022; (64(8)):e492-e499 doi:10.1097/JOM.0000000000002599.
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Impaired interferon-γ signaling promotes the development of silicosis.
Peng Z, Duan M, Tang Y, et al.
iScience 2022; (25(7)):104647 doi:10.1016/j.isci.2022.104647.
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Measurement of diffusion lung capacity (DLCO) in silicosis patients: Correlation with radiographic abnormalities on high-resolution CT scan chest.
Dixit R, Jalutharia J, Gupta A, et al.
Lung India : official organ of Indian Chest Society 2022; (39(4)):352-356 doi:10.4103/lungindia.lungindia_280_21.
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Pulmonary Toxicity of Silica Linked to Its Micro- or Nanometric Particle Size and Crystal Structure: A Review.
Marques Da Silva V, Benjdir M, Montagne P, et al.
Nanomaterials (Basel, Switzerland) 2022; (12(14)) doi:10.3390/nano12142392.
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RAB20 deficiency promotes the development of silicosis via NLRP3 inflammasome.
Peng Z, Duan M, Zhao K, et al.
Frontiers in immunology 2022; (13()):967299 doi:10.3389/fimmu.2022.967299.
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An Interesting Case of Mixed Dust Pneumoconiosis With Progressive Massive Fibrosis and Cor Pulmonale in a South American Farmer.
Alnabwani D, Prasad A, Ganta N, et al.
Cureus 2022; (14(8)):e28436 doi:10.7759/cureus.28436.
PMID: 36176824 - 59
Role of metabolic reprogramming in pro-inflammatory cytokine secretion from LPS or silica-activated macrophages.
Marrocco A, Ortiz LA
Frontiers in immunology 2022; (13()):936167 doi:10.3389/fimmu.2022.936167.
PMID: 36341426 - 60
Pulmonary function and respiratory symptoms in workers exposed to respirable silica dust: A historical cohort study.
Sohrabi Y, Sabet S, Yousefinejad S, et al.
Heliyon 2022; (8(11)):e11642 doi:10.1016/j.heliyon.2022.e11642.
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Mycobacterium tuberculosis Infection among 1,659 Silicosis Patients in Zhejiang Province, China.
Yang Q, Lin M, He Z, et al.
Microbiology spectrum 2022; (10(6)):e0145122 doi:10.1128/spectrum.01451-22.
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Colinet-Caplan Syndrome: History of an Outbreak of Autoimmune Disease in Scouring Powder Workers.
Ronsmans S, Blanc PD
Annals of internal medicine 2023; (176(2)):260-265 doi:10.7326/M22-2630.
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Pathology and Mineralogy of the Pneumoconioses.
Hua JT, Cool CD, Green FHY
Seminars in respiratory and critical care medicine 2023; (44(3)):327-339 doi:10.1055/s-0043-1764406.
PMID: 36972614 - 64
Silicosis: Emerging Trends and How to Screen for Early Detection.
Elderbrook M, Harrison R, Grajewski B, et al.
WMJ : official publication of the State Medical Society of Wisconsin 2023; (122(2)):114-117.
PMID: 37141475 - 65
Silicosis: New Challenges from an Old Inflammatory and Fibrotic Disease.
Handra CM, Gurzu IL, Chirila M, Ghita I
Frontiers in bioscience (Landmark edition) 2023; (28(5)):96 doi:10.31083/j.fbl2805096.
PMID: 37258484 - 66
Mitochondrial folate pathway regulates myofibroblast differentiation and silica-induced pulmonary fibrosis.
Qu Y, Zhai R, Wang D, et al.
Journal of translational medicine 2023; (21(1)):365 doi:10.1186/s12967-023-04241-0.
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Prevalence and risk factors for silicosis among a large cohort of stone benchtop industry workers.
Hoy RF, Dimitriadis C, Abramson M, et al.
Occupational and environmental medicine 2023; (80(8)):439-446 doi:10.1136/oemed-2023-108892.
PMID: 37328266 - 68
Workers with Suspected Diagnosis of Silicosis: A Case Study of Sarcoidosis Versus Siderosis.
Delgado-García D, Miranda-Astorga P, Delgado-Cano A, et al.
Healthcare (Basel, Switzerland) 2023; (11(12)) doi:10.3390/healthcare11121782.
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Silicosis Among Immigrant Engineered Stone (Quartz) Countertop Fabrication Workers in California.
Fazio JC, Gandhi SA, Flattery J, et al.
JAMA internal medicine 2023; (183(9)):991-998 doi:10.1001/jamainternmed.2023.3295.
PMID: 37486642 - 70
Association of spirometric restriction with mortality in the silicotics: a cohort study.
Yang S, Chan CK, Wang MH, et al.
BMC pulmonary medicine 2023; (23(1)):327 doi:10.1186/s12890-023-02622-1.
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Toward targeted treatments for silicosis.
Barnes H, Lam M, Tate MD, Hoy R
Current opinion in pulmonary medicine 2024; (30(2)):185-194 doi:10.1097/MCP.0000000000001020.
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Linking NLRP3 inflammasome and pulmonary fibrosis: mechanistic insights and promising therapeutic avenues.
Gairola S, Sinha A, Kaundal RK
Inflammopharmacology 2024; (32(1)):287-305 doi:10.1007/s10787-023-01389-5.
PMID: 37991660 - 73
Lung cancer risk and occupational pulmonary fibrosis: systematic review and meta-analysis.
Krabbe J, Steffens KM, Drießen S, Kraus T
European respiratory review : an official journal of the European Respiratory Society 2024; (33(171)) doi:10.1183/16000617.0224-2023.
PMID: 38355151 - 74
Dose-response relationship between lung function and chest imaging response to silica exposures in artificial stone manufacturing workers.
Chen CH, Tsai PJ, Chang WW, et al.
Environmental health : a global access science source 2024; (23(1)):25 doi:10.1186/s12940-024-01067-1.
PMID: 38429786 - 75
[Clinical characteristics and follow-up analysis of 63 cases of silicosis complicated with cavity-pulmonary tuberculosis].
Dong ZP, Cui QY, Pan SP, Zhao YX
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 2024; (42(4)):268-270 doi:10.3760/cma.j.cn121094-20230329-000103.
PMID: 38677989 - 76
Accuracy of chest x-ray screening of silica-exposed miners for tuberculosis.
Maboso B, Ehrlich RI
Occupational medicine (Oxford, England) 2024; (74(5)):386-391 doi:10.1093/occmed/kqae043.
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Association of smoking cessation with airflow obstruction in workers with silicosis: A cohort study.
Yang S, Chan CK, Wang MH, et al.
PloS one 2024; (19(5)):e0303743 doi:10.1371/journal.pone.0303743.
PMID: 38753732 - 78
Chest x-ray has low sensitivity to detect silicosis in artificial stone benchtop industry workers.
Hoy RF, Jones C, Newbigin K, et al.
Respirology (Carlton, Vic.) 2024; (29(9)):785-794 doi:10.1111/resp.14755.
PMID: 38802282 - 79
Autoimmune diseases, autoantibody status and silicosis in a cohort of 1238 workers from the artificial stone benchtop industry.
Tomic D, Hoy RF, Sin J, et al.
Occupational and environmental medicine 2024; (81(8)):388-394 doi:10.1136/oemed-2024-109526.
PMID: 39134395 - 80
Silicosis: No longer exclusively a chronic disease.
Cena AC, Cena LG
JAAPA : official journal of the American Academy of Physician Assistants 2024; (37(9)):14-20 doi:10.1097/01.JAA.0000000000000103.
PMID: 39162647 - 81
Silico-tuberculosis: An updated review.
Sharma S, Nayak S, R B, Singh K
The Indian journal of tuberculosis 2024; (71(4)):471-475 doi:10.1016/j.ijtb.2024.01.005.
PMID: 39278682 - 82
Correlation of spirometry findings and post-six-minute walk test oxygen desaturation in chronic simple silicosis patients with age, duration of silica exposure, smoking pack years, occupation and mean pulmonary artery pressure.
Kumari J, Advani M, Purohit G
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 2025; (95(3)) doi:10.4081/monaldi.2024.3094.
PMID: 39283145 - 83
Respiratory Oscillometry in Patients With Acute Hypoxemic Respiratory Failure.
Ponomarev D, Wu JKY, Hantos Z, et al.
Respiratory care 2025; (70(3)):227-232 doi:10.4187/respcare.12285.
PMID: 39472068 - 84
Investigation of occupational exposure to respirable crystalline silica (RCS) among engineered stone fabricators in Chicago-A pilot study.
DeVaughn A, Go LHT, Cohen RA, Shao Y
Journal of occupational and environmental hygiene 2025; (22(2)):101-109 doi:10.1080/15459624.2024.2421488.
PMID: 39585784 - 85
Efficacy and safety of a whole lung lavage program for artificial stone silicosis.
Barnes H, Pilcher D, Coull J, et al.
Journal of thoracic disease 2024; (16(11)):7630-7639 doi:10.21037/jtd-24-1050.
PMID: 39678831 - 86
Silicosis: from pathogenesis to therapeutics.
Yang B, Liu X, Peng C, et al.
Frontiers in pharmacology 2025; (16()):1516200 doi:10.3389/fphar.2025.1516200.
PMID: 39944632 - 87
Long-term exposure to low-level crystalline silica and risk assessment of silicosis: a cohort study.
Wang D, Li W, Zhou M, et al.
Thorax 2025; (80(7)):451-456 doi:10.1136/thorax-2024-222660.
PMID: 40090675 - 88
A review of silicosis and other silica-related diseases in the engineered stone countertop processing industry.
Fazio JC, Viragh K, Houlroyd J, Gandhi SA
Journal of occupational medicine and toxicology (London, England) 2025; (20(1)):9 doi:10.1186/s12995-025-00455-8.
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Erasmus Syndrome, An Autoimmunity Paradox: A Case Report and Literature Review.
Arango A, Villa-Pérez S, Garcia Rueda JE, et al.
Cureus 2025; (17(2)):e79036 doi:10.7759/cureus.79036.
PMID: 40099047 - 90
NLRP3 deficiency abrogates silica-induced neutrophil infiltration, pulmonary damage and fibrosis.
Lam M, Barry KT, Hodges CJ, et al.
Respiratory research 2025; (26(1)):109 doi:10.1186/s12931-025-03192-y.
PMID: 40119408 - 91
ROS-Dependent Endoplasmic Reticulum Stress Is Involved in Silica-Induced Pulmonary Fibrosis through the GRP78/CHOP/TXNIP/NLRP3 Signaling Pathway in Rats.
Han GZ, Li S, Cui YY, et al.
Chemical research in toxicology 2025; (38(7)):1257-1265 doi:10.1021/acs.chemrestox.5c00135.
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Silicosis research priorities for health care, research, and health and safety professionals, and for people exposed to silica in Australia: a research priority setting exercise.
Barnes H, Mathieu S, Glass DC, et al.
The Medical journal of Australia 2025; (223(5)):257-264 doi:10.5694/mja2.70013.
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Developing a Model of Health and Supportive Care for People with Silicosis in Australia.
Tikellis G, Corte T, Hoy R, et al.
Annals of the American Thoracic Society 2026; (23(1)):63-69 doi:10.1513/AnnalsATS.202503-363OC.
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