Research & Literature

Pre-conception Folic Acid and Multivitamin Supplementation for the Primary and Secondary Prevention of Neural Tube Defects and Other Folic Acid-Sensitive Congenital Anomalies.

Wilson RD, , Wilson RD, et al.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC 2015; (37(6)):534-52 doi:10.1016/s1701-2163(15)30230-9.

Magnetic Resonance Imaging Evaluation of Fetal Neural Tube Defects.

Egloff A, Bulas D

Seminars in ultrasound, CT, and MR 2015; (36(6)):487-500.

Chorioamniotic membrane separation and preterm premature rupture of membranes complicating in utero myelomeningocele repair.

Soni S, Moldenhauer JS, Spinner SS, et al.

American journal of obstetrics and gynecology 2016; (214(5)):647.e1-7.

Screening for Open Neural Tube Defects.

Krantz DA, Hallahan TW, Carmichael JB

Clinics in laboratory medicine 2016; (36(2)):401-6.

Screening for Spinal Dysraphisms in Newborns With Sacral Dimples.

Wilson P, Hayes E, Barber A, Lohr J

Clinical pediatrics 2016; (55(11)):1064-70 doi:10.1177/0009922816664061.

Ultrasonography and magnetic resonance imaging evaluation of pediatric spinal anomalies.

Dhingani DD, Boruah DK, Dutta HK, Gogoi RK

Journal of pediatric neurosciences 2016; (11(3)):206-212 doi:10.4103/1817-1745.193374.

Fetoscopic Open Neural Tube Defect Repair: Development and Refinement of a Two-Port, Carbon Dioxide Insufflation Technique.

Belfort MA, Whitehead WE, Shamshirsaz AA, et al.

Obstetrics and gynecology 2017; (129(4)):734-743 doi:10.1097/AOG.0000000000001941.

Spina Bifida: Pathogenesis, Mechanisms, and Genes in Mice and Humans.

Mohd-Zin SW, Marwan AI, Abou Chaar MK, et al.

Scientifica 2017; (2017()):5364827 doi:10.1155/2017/5364827.

[Prenatal diagnosis of neural tube defects: Correlation between prenatal and postnatal data].

Matuszewski L, Perdriolle-Galet E, Clerc-Urmès I, et al.

Journal of gynecology obstetrics and human reproduction 2017; (46(3)):291-296 doi:10.1016/j.jogoh.2016.10.009.

Tethered cord syndrome with spina bifida aperta in cats: two case reports of different types.

Tamura M, Oji T, Une S, et al.

JFMS open reports 2017; (3(1)):2055116917708060 doi:10.1177/2055116917708060.

Prenatal diagnosis of spina bifida: from intracranial translucency to intrauterine surgery.

Sepulveda W, Wong AE, Sepulveda F, et al.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2017; (33(7)):1083-1099 doi:10.1007/s00381-017-3445-7.

Long-Term Complications of the Neurogenic Bladder.

Nseyo U, Santiago-Lastra Y

The Urologic clinics of North America 2017; (44(3)):355-366 doi:10.1016/j.ucl.2017.04.003.

Tocolysis for in utero Surgery: Atosiban Performs Distinctly Better than Magnesium Sulfate.

Ochsenbein-Kölble N, Krähenmann F, Hüsler M, et al.

Fetal diagnosis and therapy 2018; (44(1)):59-64 doi:10.1159/000478261.

Committee Opinion No. 720: Maternal-Fetal Surgery for Myelomeningocele.

Obstetrics and gynecology 2017; (130(3)):e164-e167 doi:10.1097/AOG.0000000000002303.

Fetal Surgery for Myelomeningocele: A Systematic Review and Meta-Analysis of Outcomes in Fetoscopic versus Open Repair.

Kabagambe SK, Jensen GW, Chen YJ, et al.

Fetal diagnosis and therapy 2018; (43(3)):161-174 doi:10.1159/000479505.

Fetal surgery for myelomeningocele: After the Management of Myelomeningocele Study (MOMS).

Moldenhauer JS, Adzick NS

Seminars in fetal & neonatal medicine 2017; (22(6)):360-366 doi:10.1016/j.siny.2017.08.004.

Mood-Stabilizing Anticonvulsants, Spina Bifida, and Folate Supplementation: Commentary.

Patel N, Viguera AC, Baldessarini RJ

Journal of clinical psychopharmacology 2018; (38(1)):7-10 doi:10.1097/JCP.0000000000000813.

The Management of Myelomeningocele Study: full cohort 30-month pediatric outcomes.

Farmer DL, Thom EA, Brock JW, et al.

American journal of obstetrics and gynecology 2018; (218(2)):256.e1-256.e13 doi:10.1016/j.ajog.2017.12.001.

Ultrasound and magnetic resonance imaging in the prenatal diagnosis of open spina bifida.

Micu R, Chicea AL, Bratu DG, et al.

Medical ultrasonography 2018; (20(2)):221-227 doi:10.11152/mu-1325.

Co-morbidities Associated With Early Mortality in Adults With Spina Bifida.

Dicianno BE, Sherman A, Roehmer C, Zigler CK

American journal of physical medicine & rehabilitation 2018; (97(12)):861-865 doi:10.1097/PHM.0000000000000964.

Homologous cryopreserved amniotic membrane in the repair of myelomeningocele: preliminary experience.

Marton E, Giordan E, Gioffrè G, et al.

Acta neurochirurgica 2018; (160(8)):1625-1631 doi:10.1007/s00701-018-3577-x.

Improved Bowel Function in Patients with Spina Bifida After Bone Marrow-Derived Mononuclear Cell Transplantation: A Report of 2 Cases.

Liem NT, Chinh VD, Thinh NT, et al.

The American journal of case reports 2018; (19()):1010-1018 doi:10.12659/AJCR.909801.

Spontaneous Pneumocephalus Secondary to Leaking Myelomeningocele.

Kutty RK, Sreemathyamma SB, Sivanandapanicker JL, Peethambaran A

Journal of pediatric neurosciences 2018; (13(3)):329-330 doi:10.4103/JPN.JPN_17_18.

Myelomeningocele Versus Myelocele on Fetal MR Images: Are There Differences in Brain Findings?

Nagaraj UD, Bierbrauer KS, Stevenson CB, et al.

AJR. American journal of roentgenology 2018; (211(6)):1376-1380 doi:10.2214/AJR.18.20088.

Plastic and Orthopaedic Interventions and Long-Term Sequelae in Children with Meningococcal Septicemia-40 Years of Experience at the University Children's Hospital Zurich.

Elrod J, Mannhard D, Mohr C, et al.

European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie 2019; (29(5)):462-469 doi:10.1055/s-0038-1673705.

Fetoscopic spina bifida repair.

Miller JL, Groves ML, Baschat AA

Minerva ginecologica 2019; (71(2)):163-170 doi:10.23736/S0026-4784.18.04355-1.

Team Approach: Guideline-Based Management of Skin Injury in Individuals with Myelomeningocele.

Bradko V, Hill J, Castillo H, Castillo J

JBJS reviews 2019; (7(3)):e1 doi:10.2106/JBJS.RVW.18.00062.

Subsequent pregnancy outcomes after open maternal-fetal surgery for myelomeningocele.

Goodnight WH, Bahtiyar O, Bennett KA, et al.

American journal of obstetrics and gynecology 2019; (220(5)):494.e1-494.e7 doi:10.1016/j.ajog.2019.03.008.

Association of maternal risk factors with the recent rise of neural tube defects in Canada.

Liu S, Evans J, MacFarlane AJ, et al.

Paediatric and perinatal epidemiology 2019; (33(2)):145-153 doi:10.1111/ppe.12543.

Comparison of brain microstructure after prenatal spina bifida repair by either laparotomy-assisted fetoscopic or open approach.

Sanz Cortes M, Torres P, Yepez M, et al.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2020; (55(1)):87-95 doi:10.1002/uog.20373.

Fetal surgery for spina bifida.

Dewan MC, Wellons JC

Journal of neurosurgery. Pediatrics 2019; (24(2)):105-114.

Survey of U.S. adults with spina bifida.

Morley CP, Struwe S, Pratte MA, et al.

Disability and health journal 2020; (13(2)):100833 doi:10.1016/j.dhjo.2019.100833.

Detailed Analysis of Hydrocephalus and Hindbrain Herniation After Prenatal and Postnatal Myelomeningocele Closure: Report From a Single Institution.

Flanders TM, Heuer GG, Madsen PJ, et al.

Neurosurgery 2020; (86(5)):637-645 doi:10.1093/neuros/nyz302.

Laboratory screening and diagnosis of open neural tube defects, 2019 revision: a technical standard of the American College of Medical Genetics and Genomics (ACMG).

Palomaki GE, Bupp C, Gregg AR, et al.

Genetics in medicine : official journal of the American College of Medical Genetics 2020; (22(3)):462-474 doi:10.1038/s41436-019-0681-0.

Spina bifida transition to adult healthcare guidelines.

Fremion EJ, Dosa NP

Journal of pediatric rehabilitation medicine 2019; (12(4)):423-429 doi:10.3233/PRM-190633.

The use of mirabegron in neurogenic bladder: a systematic review.

El Helou E, Labaki C, Chebel R, et al.

World journal of urology 2020; (38(10)):2435-2442 doi:10.1007/s00345-019-03040-x.

Spinal Dysraphism in the Last Two Decades : What I Have Seen during the Era of Dynamic Advancement.

Wang KC

Journal of Korean Neurosurgical Society 2020; (63(3)):272-278 doi:10.3340/jkns.2020.0068.

Does India need 'mandatory flour fortification with folic acid' policy to prevent neural tube defects?

Yadav V, Dabar D, Prasad P, et al.

Journal of family medicine and primary care 2020; (9(7)):3787-3788 doi:10.4103/jfmpc.jfmpc_396_20.

Brain malformations and cognitive performance in spina bifida.

Schneider J, Mohr N, Aliatakis N, et al.

Developmental medicine and child neurology 2021; (63(3)):295-302 doi:10.1111/dmcn.14717.

Virtual navigation for the improvement of parents counseling and the planning of fetal endoscopic myelomeningocele repair.

Werner H, Ribeiro G, Lopes J, et al.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2021; (37(3)):969-972 doi:10.1007/s00381-020-04961-4.

Brain malformations and spina bifida.

Fletcher JM, Kulesz PA

Developmental medicine and child neurology 2021; (63(3)):244 doi:10.1111/dmcn.14745.

Intracranial Translucency, Its Use as a Potential First Trimester Ultrasound Marker for Screening of Neural Tube Defects.

Sepúlveda-González G, Arroyo-Lemarroy T, Basurto D, et al.

Diagnostics (Basel, Switzerland) 2020; (10(11)) doi:10.3390/diagnostics10110986.

Mobility guidelines for the care of people with spina bifida.

Wilson PE, Mukherjee S

Journal of pediatric rehabilitation medicine 2020; (13(4)):621-627 doi:10.3233/PRM-200744.

Impact of Early Conventional Treatment on Adult Bone and Joints in a Murine Model of X-Linked Hypophosphatemia.

Cauliez A, Zhukouskaya VV, Hilliquin S, et al.

Frontiers in cell and developmental biology 2020; (8()):591417 doi:10.3389/fcell.2020.591417.

Experience of 300 cases of prenatal fetoscopic open spina bifida repair: report of the International Fetoscopic Neural Tube Defect Repair Consortium.

Sanz Cortes M, Chmait RH, Lapa DA, et al.

American journal of obstetrics and gynecology 2021; (225(6)):678.e1-678.e11 doi:10.1016/j.ajog.2021.05.044.

Impact of the cystic neural tube defects on fetal motor function in prenatal myelomeningocele repairs: A retrospective cohort study.

Corroenne R, Sanz Cortes M, Johnson RM, et al.

Prenatal diagnosis 2021; (41(8)):965-971 doi:10.1002/pd.5992.

Cutaneous Stigmata of the Spine: A Review of Indications for Imaging and Referral.

Behbahani M, Lam SK, Bowman R

Pediatric clinics of North America 2021; (68(4)):895-913 doi:10.1016/j.pcl.2021.04.017.

Arnold-Chiari Malformation: Core Concepts.

Fons K, Jnah AJ

Neonatal network : NN 2021; (40(5)):313-320 doi:10.1891/11-T-704.

The Efficacy and Safety of Mirabegron for the Treatment of Neurogenic Lower Urinary Tract Dysfunction: A Systematic Review and Meta-analysis.

Zhang D, Sun F, Yao H, et al.

Frontiers in pharmacology 2021; (12()):756582 doi:10.3389/fphar.2021.756582.

Factors Associated With Neural Tube Defects Among Newborns Delivered at Debre Berhan Specialized Hospital, North Eastern Ethiopia, 2021. Case-Control Study.

Mulu GB, Atinafu BT, Tarekegn FN, et al.

Frontiers in pediatrics 2021; (9()):795637 doi:10.3389/fped.2021.795637.

Ultrasound evaluation of uterine scar thickness after open fetal surgery for myelomeningocele.

Sasaoka AKS, Moron AF, Araujo Júnior E, et al.

Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2023; (39(3)):655-661 doi:10.1007/s00381-022-05642-0.

Fetal magnetic resonance imaging in the diagnosis of spinal cord neural tube defects: A prospective study.

Gao G, Tao B, Chen Y, et al.

Frontiers in neurology 2022; (13()):944666 doi:10.3389/fneur.2022.944666.

Late diagnosis of dorsolumbar lipomyelomeningocele with tethered cord in a middle aged adult: A case report from Nepal.

Aryal S, Poudel S, Sharma S, Deo S

Radiology case reports 2022; (17(12)):4532-4536 doi:10.1016/j.radcr.2022.08.064.

Fetal Repair of Neural Tube Defects.

Lee SY, Papanna R, Farmer D, Tsao K

Clinics in perinatology 2022; (49(4)):835-848 doi:10.1016/j.clp.2022.06.004.

Folic acid fortification of flour to prevent neural tube defects in Europe - A position statement by the European Board and college of obstetrics and gynaecology (EBCOG).

Petch S, McAuliffe F, O'Reilly S, et al.

European journal of obstetrics, gynecology, and reproductive biology 2022; (279()):109-111 doi:10.1016/j.ejogrb.2022.10.010.

A rare case of thoracic lipomyelomeningocele in a young female: A case report.

Sharma S, Khadka H, Aryal S

Radiology case reports 2023; (18(3)):1372-1375 doi:10.1016/j.radcr.2022.10.042.

Multidisciplinary management of people with spina bifida across the lifespan.

Koch VH, Lopes M, Furusawa E, et al.

Pediatric nephrology (Berlin, Germany) 2024; (39(3)):681-697 doi:10.1007/s00467-023-06067-w.

Midline cutaneous anomalies of the craniospinal axis.

Ren F, Bressler L, Pruitt L, et al.

Journal of the American Academy of Dermatology 2023; (89(6)):1238-1244 doi:10.1016/j.jaad.2023.06.062.

Thalamic connectivity topography in newborns with spina bifida: association with neurological functional level but not developmental outcome at 2 years.

Ji H, Payette K, Speckert A, et al.

Cerebral cortex (New York, N.Y. : 1991) 2024; (34(1)) doi:10.1093/cercor/bhad438.

Barriers to Transitional Care in Spina Bifida.

Hwang CK, Harris KT, Wood D

The Urologic clinics of North America 2024; (51(2)):187-196 doi:10.1016/j.ucl.2024.01.006.

Indications and added value of videourodynamics in men with spinal cord injury.

Françot M, Lefevre C, Reiss B, et al.

BJUI compass 2024; (5(8)):761-769 doi:10.1002/bco2.370.

Single-cell transcriptomics reveals the cellular identity of a novel progenitor population crucial for murine neural tube closure.

Deng Z, Carpinelli MR, Butt T, et al.

Heliyon 2024; (10(17)):e37259 doi:10.1016/j.heliyon.2024.e37259.

Health status, functioning and risk profiles for secondary health conditions in adolescents and young adults with spina bifida: a cross-sectional study at time of transition.

Eriks-Hoogland I, Schwethelm M, Müller L, et al.

Swiss medical weekly 2024; (154()):3836 doi:10.57187/s.3836.

Laparotomy-assisted, two-port fetoscopic myelomeningocele repair: infant to preschool outcomes.

Sanz-Cortes M, Whitehead WE, Johnson RM, et al.

Journal of neurosurgery. Pediatrics 2025; (35(1)):10-21 doi:10.3171/2024.7.PEDS24200.

Spinal neural tube formation and tail development in human embryos.

Santos C, Marshall AR, Murray A, et al.

eLife 2024; (12()).

Neurogenic bladder pathophysiology, assessment and management after lumbar diseases.

Hao J, Jiang J, Han Q, et al.

EFORT open reviews 2025; (10(3)):156-165 doi:10.1530/EOR-24-0087.

Sleep-related breathing disorders in children with spina bifida.

Nandalike K, Hobart-Porter LJ

Journal of pediatric rehabilitation medicine 2024; (17(4)):414-419 doi:10.1177/18758894241300260.

The contribution of de novo coding mutations to meningomyelocele.

Ha YJ, Nisal A, Tang I, et al.

Nature 2025; (641(8062)):419-426 doi:10.1038/s41586-025-08676-x.

Walking Function and Capacity in Middle-Aged and Older (59-66y) Adults With Spina Bifida Myelomeningocele: A 4-Year Follow-up Study.

Klund-Hansen SL, Larsen KL, Lidal IB, et al.

Archives of rehabilitation research and clinical translation 2025; (7(1)):100420 doi:10.1016/j.arrct.2024.100420.

Comparing Folic Acid Interventions and Arsenic Reduction Strategies for Neural Tube Defect Prevention in Bangladesh: A Systematic Review and Decision Analysis.

Wei CF, Choma EF, Wang X, et al.

Birth defects research 2025; (117(6)):e2494 doi:10.1002/bdr2.2494.

Spina bifida as a multifactorial birth defect: Risk factors and genetic underpinnings.

Wong ES, Hu DA, Zhang L, et al.

Pediatric discovery 2025; (3(2)):e2517 doi:10.1002/pdi3.2517.

Understanding Orthopaedic and Health-related Quality of Life Outcomes in Patients With Myelomeningocele Functional Classification 1 Spina Bifida in Relationship to Supportive Standing.

Shen P, Swaroop VT, Rojas AM, et al.

Journal of the Pediatric Orthopaedic Society of North America 2025; (12()):100205 doi:10.1016/j.jposna.2025.100205.

Intermittent catheterization: A patient-centric approach is key to optimal management of neurogenic lower urinary tract dysfunction.

Krassioukov A, Welk B, Vrijens D, et al.

Frontiers in urology 2023; (3()):1158260 doi:10.3389/fruro.2023.1158260.

Closed spinal dysraphism: Think about it in the case of enuresis in children.

Kessi EMCJ, Maslouhi K, Diallo ID, et al.

Radiology case reports 2025; (20(10)):5255-5257 doi:10.1016/j.radcr.2025.06.114.

Comparative diagnostic accuracy of ultrasound and magnetic resonance imaging for spinal dysraphism in infants: insights from a single-center study.

Daqqaq TS

Radiologie (Heidelberg, Germany) 2025; (65(Suppl 1)):93-99 doi:10.1007/s00117-025-01494-2.

Fetal Myelomeningocele Closure in the Setting of Maternal Body Mass Index 35 to 40.

Hersh DS, Anuar A, Bennett KA, et al.

Neurosurgery 2026; (98(6)):1278-1287 doi:10.1227/neu.0000000000003802.

Sacral dimple: clinical perspectives of lesions hidden beneath the skin.

Eun J, Lee KS, Yang SH

Clinical and experimental pediatrics 2026; (69(2)):103-113 doi:10.3345/cep.2025.01802.