Research & Literature

Botulinum toxin A in the treatment of trigeminal neuralgia.

Xia JH, He CH, Zhang HF, et al.

The International journal of neuroscience 2016; (126(4)):348-53 doi:10.3109/00207454.2015.1019624.

Evaluation of cytochrome P450 inductions by anti-epileptic drug oxcarbazepine, 10-hydroxyoxcarbazepine, and carbamazepine using human hepatocytes and HepaRG cells.

Sugiyama I, Murayama N, Kuroki A, et al.

Xenobiotica; the fate of foreign compounds in biological systems 2016; (46(9)):765-74 doi:10.3109/00498254.2015.1118774.

Real-time intraoperative monitoring of brainstem auditory evoked potentials during microvascular decompression for hemifacial spasm.

Joo BE, Park SK, Cho KR, et al.

Journal of neurosurgery 2016; (125(5)):1061-1067 doi:10.3171/2015.10.JNS151224.

Trigeminal neuralgia: New classification and diagnostic grading for practice and research.

Cruccu G, Finnerup NB, Jensen TS, et al.

Neurology 2016; (87(2)):220-8 doi:10.1212/WNL.0000000000002840.

A Case Report About Cluster-Tic Syndrome Due to Venous Compression of the Trigeminal Nerve.

de Coo I, van Dijk JM, Metzemaekers JD, Haan J

Headache 2017; (57(4)):654-657 doi:10.1111/head.12990.

Using Diffusion Tensor Imaging to Evaluate Microstructural Changes and Outcomes after Radiofrequency Rhizotomy of Trigeminal Nerves in Patients with Trigeminal Neuralgia.

Chen ST, Yang JT, Yeh MY, et al.

PloS one 2016; (11(12)):e0167584 doi:10.1371/journal.pone.0167584.

After microvascular decompression to treat trigeminal neuralgia, both immediate pain relief and recurrence rates are higher in patients with arterial compression than with venous compression.

Shi L, Gu X, Sun G, et al.

Oncotarget 2017; (8(27)):44819-44823 doi:10.18632/oncotarget.14765.

Tic, Triggering, and Tearing: From CTN to SUNHA.

Benoliel R, Sharav Y, Haviv Y, Almoznino G

Headache 2017; (57(6)):997-1009 doi:10.1111/head.13040.

Trigeminal Neuralgia.

Cruccu G

Continuum (Minneapolis, Minn.) 2017; (23(2, Selected Topics in Outpatient Neurology)):396-420 doi:10.1212/CON.0000000000000451.

Persistent idiopathic facial pain.

Benoliel R, Gaul C

Cephalalgia : an international journal of headache 2017; (37(7)):680-691 doi:10.1177/0333102417706349.

Stevens-Johnson Syndrome following Failure of Genetic Screening prior to Carbamazepine Prescription.

Nasir SA, Tan HL, Tan HJ, et al.

Case reports in dentistry 2017; (2017()):4201357 doi:10.1155/2017/4201357.

Triggering trigeminal neuralgia.

Di Stefano G, Maarbjerg S, Nurmikko T, et al.

Cephalalgia : an international journal of headache 2018; (38(6)):1049-1056 doi:10.1177/0333102417721677.

The emerging role of gamma knife radiosurgery in the management of glossopharyngeal neuralgia.

Spina A, Boari N, Gagliardi F, et al.

Neurosurgical review 2019; (42(1)):31-38 doi:10.1007/s10143-017-0886-0.

Neuromodulation and Devices in Trigeminal Neuralgia.

Weber K

Headache 2017; (57(10)):1648-1653 doi:10.1111/head.13166.

Trigeminal Neuralgia.

Yadav YR, Nishtha Y, Sonjjay P, et al.

Asian journal of neurosurgery 2017; (12(4)):585-597 doi:10.4103/ajns.AJNS_67_14.

Accommodation to Diagnosis of Trigeminal Neuralgia

Bašić Kes V, Zadro Matovina L

Acta clinica Croatica 2017; (56(1)):157-161 doi:10.20471/acc.2017.56.01.21.

Effectiveness of Gamma Knife Radiosurgery in Improving Psychophysical Performance and Patient's Quality of Life in Idiopathic Trigeminal Neuralgia.

Gagliardi F, Spina A, Bailo M, et al.

World neurosurgery 2018; (110()):e776-e785 doi:10.1016/j.wneu.2017.11.096.

Postherpetic Neuralgia and Trigeminal Neuralgia.

Feller L, Khammissa RAG, Fourie J, et al.

Pain research and treatment 2017; (2017()):1681765 doi:10.1155/2017/1681765.

Early Stereotactic Radiosurgery for Medically Refractory Trigeminal Neuralgia.

Lee CC, Chen CJ, Chong ST, et al.

World neurosurgery 2018; (112()):e569-e575 doi:10.1016/j.wneu.2018.01.088.

Favourable prognosis of trigeminal neuralgia when enrolled in a multidisciplinary management program - a two-year prospective real-life study.

Heinskou TB, Maarbjerg S, Wolfram F, et al.

The journal of headache and pain 2019; (20(1)):23 doi:10.1186/s10194-019-0973-4.

European Academy of Neurology guideline on trigeminal neuralgia.

Bendtsen L, Zakrzewska JM, Abbott J, et al.

European journal of neurology 2019; (26(6)):831-849 doi:10.1111/ene.13950.

GABAB receptor activation attenuates inflammatory orofacial pain by modulating interleukin-1β in satellite glial cells: Role of NF-κB and MAPK signaling pathways.

Liu F, Zhang YY, Song N, et al.

Brain research bulletin 2019; (149()):240-250 doi:10.1016/j.brainresbull.2019.04.018.

Role of Fused Three-Dimensional Time-of-Flight Magnetic Resonance Angiography and 3-Dimensional T2-Weighted Imaging Sequences in Neurovascular Compression.

Gamaleldin OA, Donia MM, Elsebaie NA, et al.

World neurosurgery 2020; (133()):e180-e186 doi:10.1016/j.wneu.2019.08.190.

Trigeminal neuralgia: An overview from pathophysiology to pharmacological treatments.

Gambeta E, Chichorro JG, Zamponi GW

Molecular pain 2020; (16()):1744806920901890 doi:10.1177/1744806920901890.

Effectiveness and safety of CyberKnife radiosurgery in treatment of trigeminalgia - experiences of Polish neurological and oncological centres.

Bal W, Łabuz-Roszak B, Tarnawski R, Lasek-Bal A

Neurologia i neurochirurgia polska 2020; (54(1)):28-32 doi:10.5603/PJNNS.a2020.0009.

Pharmacogenomics in Asian Subpopulations and Impacts on Commonly Prescribed Medications.

Lo C, Nguyen S, Yang C, et al.

Clinical and translational science 2020; (13(5)):861-870 doi:10.1111/cts.12771.

Oxcarbazepine for trigeminal neuralgia may induce lower extremity weakness: A case report.

Song HG, Nahm FS

World journal of clinical cases 2020; (8(5)):922-927 doi:10.12998/wjcc.v8.i5.922.

Usage Pattern of Carbamazepine and Associated Severe Cutaneous Adverse Reactions in Singapore Following Implementation of HLA-B*15:02 Genotyping as Standard-of-Care.

Sung C, Tan L, Limenta M, et al.

Frontiers in pharmacology 2020; (11()):527 doi:10.3389/fphar.2020.00527.

Concomitant continuous pain in patients with trigeminal neuralgia is associated with trigeminal nerve root atrophy.

Di Stefano G, De Stefano G, Leone C, et al.

Cephalalgia : an international journal of headache 2020; (40(13)):1502-1510 doi:10.1177/0333102420949206.

Advances in diagnosis, classification, pathophysiology, and management of trigeminal neuralgia.

Bendtsen L, Zakrzewska JM, Heinskou TB, et al.

The Lancet. Neurology 2020; (19(9)):784-796 doi:10.1016/S1474-4422(20)30233-7.

Chronic Facial Pain: Trigeminal Neuralgia, Persistent Idiopathic Facial Pain, and Myofascial Pain Syndrome-An Evidence-Based Narrative Review and Etiological Hypothesis.

Gerwin R

International journal of environmental research and public health 2020; (17(19)) doi:10.3390/ijerph17197012.

Please spare my teeth! Dental procedures and trigeminal neuralgia.

Tripathi M, Sadashiva N, Gupta A, et al.

Surgical neurology international 2020; (11()):455 doi:10.25259/SNI_729_2020.

Real-world effectiveness and tolerability of carbamazepine and oxcarbazepine in 354 patients with trigeminal neuralgia.

Di Stefano G, De Stefano G, Leone C, et al.

European journal of pain (London, England) 2021; (25(5)):1064-1071 doi:10.1002/ejp.1727.

The Impact of Neuronavigation on the Surgical Outcome of Microvascular Decompression for Trigeminal Neuralgia.

Legninda Sop FY, D'Ercole M, Izzo A, et al.

World neurosurgery 2021; (149()):80-85 doi:10.1016/j.wneu.2021.02.063.

Association Between Trigeminal Neuralgia And Unnecessary Tooth Extraction.

Rehman A, Abbas I, , et al.

Journal of Ayub Medical College, Abbottabad : JAMC 2021; (33(1)):116-119.

Trigeminal neuralgia: a practical guide.

Lambru G, Zakrzewska J, Matharu M

Practical neurology 2021; (21(5)):392-402 doi:10.1136/practneurol-2020-002782.

Epidemiology of trigeminal neuralgia: an electronic population health data study in Korea.

Lee CH, Jang HY, Won HS, et al.

The Korean journal of pain 2021; (34(3)):332-338 doi:10.3344/kjp.2021.34.3.332.

The changing face of trigeminal neuralgia-A narrative review.

Maarbjerg S, Benoliel R

Headache 2021; (61(6)):817-837 doi:10.1111/head.14144.

Rehabilitation therapy outside of the hospital via the Internet combined with suggestive psychological intervention in patients with trigeminal neuralgia.

Tang X, Sun J, Xia H, Dong M

American journal of translational research 2021; (13(6)):6837-6845.

Percutaneous Radiofrequency Thermocoagulation in Trigeminal Neuralgia : Analysis of Early and Late Outcomes of 156 Cases and 209 Interventions.

Gunduz HB, Cevik OM, Asilturk M, et al.

Journal of Korean Neurosurgical Society 2021; (64(5)):827-836 doi:10.3340/jkns.2020.0333.

Altered somatosensory processing in secondary trigeminal neuralgia: A case report.

Noma N, Ozasa K, Young A

Journal of Indian Prosthodontic Society 2021; (21(3)):308-310 doi:10.4103/jips.jips_75_21.

Cortical thickness, gyrification and sulcal depth in trigeminal neuralgia.

Li M, Yan J, Wen H, et al.

Scientific reports 2021; (11(1)):16322 doi:10.1038/s41598-021-95811-z.

Comparison of Microvascular Decompression and Two Isocenters Gamma Knife for the Treatment of Trigeminal Neuralgia Caused by Vertebrobasilar Dolichoectasia.

Zhao Z, Chai S, Wang J, et al.

Frontiers in neurology 2021; (12()):707985 doi:10.3389/fneur.2021.707985.

Effects of Botulinum Toxin Type A on Pain among Trigeminal Neuralgia, Myofascial Temporomandibular Disorders, and Oromandibular Dystonia.

Yoshida K

Toxins 2021; (13(9)) doi:10.3390/toxins13090605.

Microvascular decompression in trigeminal neuralgia: predictors of pain relief, complication avoidance, and lessons learned.

Herta J, Schmied T, Loidl TB, et al.

Acta neurochirurgica 2021; (163(12)):3321-3336 doi:10.1007/s00701-021-05028-2.

Trigeminal Neuralgia: Current Approaches and Emerging Interventions.

Xu R, Xie ME, Jackson CM

Journal of pain research 2021; (14()):3437-3463 doi:10.2147/JPR.S331036.

Radiofrequency thermocoagulation for the treatment of trigeminal neuralgia.

Wang Z, Wang Z, Li K, et al.

Experimental and therapeutic medicine 2022; (23(1)):17 doi:10.3892/etm.2021.10939.

A Systematic Review of Repeat Microvascular Decompression for Recurrent or Persistent Trigeminal Neuralgia.

Jiao L, Ye H, Lv J, et al.

World neurosurgery 2022; (158()):226-233 doi:10.1016/j.wneu.2021.11.129.

Intravenous fosphenytoin as treatment for acute exacerbation of trigeminal neuralgia: A prospective systematic study of 15 patients.

Andersen ASS, Heinskou TB, Asghar MS, et al.

Cephalalgia : an international journal of headache 2022; (42(11-12)):1138-1147 doi:10.1177/03331024221094536.

Associations of HLA genetic variants with carbamazepine-induced cutaneous adverse drug reactions: An updated meta-analysis.

Biswas M, Ershadian M, Shobana J, et al.

Clinical and translational science 2022; (15(8)):1887-1905 doi:10.1111/cts.13291.

Treatment of acute exacerbations of trigeminal neuralgia in the emergency department: A retrospective case series.

Pinto MJ, Gomes A, Pinto M, et al.

Headache 2022; (62(8)):1002-1006 doi:10.1111/head.14373.

[Trigeminal Neuralgia - What Do We Know about the Causes, Diagnosis and Treatment?]

Zoller S, Oertel MF, Stieglitz LH

Praxis 2022; (111(13)):731-737 doi:10.1024/1661-8157/a003918.

Narrow ovale foramina may be involved in the development of primary trigeminal neuralgia.

Li S, Liao C, Qian M, et al.

Frontiers in neurology 2022; (13()):1013216 doi:10.3389/fneur.2022.1013216.

Microvascular decompression in trigeminal neuralgia - a prospective study of 115 patients.

Andersen ASS, Heinskou TB, Rochat P, et al.

The journal of headache and pain 2022; (23(1)):145 doi:10.1186/s10194-022-01520-x.

Treatment of multiple sclerosis-related trigeminal neuralgia with onabotulinumtoxinA.

Asan F, Gündüz A, Tütüncü M, et al.

Headache 2022; (62(10)):1322-1328 doi:10.1111/head.14414.

Different MRI-based methods for the diagnosis of neurovascular compression in trigeminal neuralgia or hemifacial spasm: A network meta-analysis.

Liang C, Yang L, Reichardt W, et al.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2023; (108()):19-24 doi:10.1016/j.jocn.2022.12.016.

Incidence of trigeminal neuralgia: A population-based study in Central Sweden.

Svedung Wettervik T, Snel D, Kristiansson P, et al.

European journal of pain (London, England) 2023; (27(5)):580-587 doi:10.1002/ejp.2081.

Correlation of Preoperative High-Resolution Neurovascular Imaging and Surgical Success in Neurovascular Compression Syndromes.

Busse S, Taylor J, Field M

World neurosurgery 2023; (172()):e593-e598 doi:10.1016/j.wneu.2023.01.094.

TREATMENT OPTIONS FOR TRIGEMINAL NEURALGIA.

Radoš I

Acta clinica Croatica 2022; (61(Suppl 2)):96-102 doi:10.20471/acc.2022.61.s2.12.

Knowledge and experience of dentists with patients with trigeminal neuralgia: A prospective, cross-sectional survey study.

Tuncer Z, Akbulut N, Ozturk V, Beyaz SG

Cranio : the journal of craniomandibular practice 2024; (42(1)):84-89 doi:10.1080/08869634.2023.2197828.

Percutaneous balloon compression for trigeminal neuralgia: experience and surgical techniques from a single institution.

Deng S, Luo J, Lai M, et al.

Acta neurologica Belgica 2023; (123(6)):2295-2302 doi:10.1007/s13760-023-02310-1.

Impact on carbamazepine usage and cutaneous adverse reactions before and after the reimbursement of HLA-B*1502 genotyping in Taiwan, 2000-2017: A nationwide longitudinal study.

Chang BL, Liu JR, Chang SH, See LC

Epilepsia 2023; (64(10)):2679-2689 doi:10.1111/epi.17726.

Low-dose Fosphenytoin for Aborting Acute Trigeminal Neuralgia Pain: A Case Report.

Baydoun J, Lin A, Miya J

Clinical practice and cases in emergency medicine 2023; (7(3)):182-184 doi:10.5811/cpcem.1603.

Considerations When Using Gabapentinoids to Treat Trigeminal Neuralgia: A Review.

De Stefano G, Di Pietro G, Truini A, et al.

Neuropsychiatric disease and treatment 2023; (19()):2007-2012 doi:10.2147/NDT.S407543.

Comparison of microvascular decompression, percutaneous radiofrequency rhizotomy, and stereotactic radiosurgery in the treatment of trigeminal neuralgia: A long term quasi-experimental study.

Altamirano JM, Jimenez-Olvera M, Moreno-Jimenez S, et al.

Pain practice : the official journal of World Institute of Pain 2024; (24(3)):514-524 doi:10.1111/papr.13327.

Bibliometric Analysis of the Top 100 Cited Articles and Author H-Indexes on the Surgical Treatment of Trigeminal Neuralgia.

Ong V, Schupper AJ, Bederson JB, et al.

World neurosurgery 2024; (184()):44-62 doi:10.1016/j.wneu.2024.01.029.

[Stereotactic Radiosurgery for Trigeminal Neuralgia].

Kobayashi M

No shinkei geka. Neurological surgery 2024; (52(1)):70-76 doi:10.11477/mf.1436204881.

A prospective cohort study on perioperative percutaneous balloon compression for trigeminal neuralgia: safety and efficacy analysis.

Tang Q, Gao S, Wang C, et al.

Neurosurgical review 2024; (47(1)):86 doi:10.1007/s10143-024-02323-1.

Pharmacogenetics and Oxcarbazepine in Children and Adolescents: Beyond HLA-B*15:02.

Stancil SL, Sandritter T, Strawn JR

Journal of child and adolescent psychopharmacology 2024; (34(1)):61-66 doi:10.1089/cap.2023.0064.

Repeat Surgery for Recurrent or Refractory Trigeminal Neuralgia: A Systematic Review and Meta-Analysis.

Rheaume AR, Pietrosanu M, Ostertag C, Sankar T

World neurosurgery 2024; (185()):370-380.e2 doi:10.1016/j.wneu.2024.02.097.

Hyponatremia-induced worsening of trigeminal neuralgia- When the sodium plays the game.

Ansari MZ, Singh R, Mohanty B, et al.

Journal of family medicine and primary care 2024; (13(1)):378-380 doi:10.4103/jfmpc.jfmpc_1187_23.

Safety and efficacy of carbamazepine in the treatment of trigeminal neuralgia: A metanalysis in biomedicine.

Guo M, Shen W, Zhou M, et al.

Mathematical biosciences and engineering : MBE 2024; (21(4)):5335-5359 doi:10.3934/mbe.2024235.

The Challenges in Clinical Diagnosis of Trigeminal Neuralgia: A Review.

Pergolizzi JV, LeQuang JAK, El-Tallawy SN, et al.

Cureus 2024; (16(6)):e61898 doi:10.7759/cureus.61898.

Treatment of recurrent trigeminal neuralgia after microvascular decompression: How to select.

Lv W, Qin Y, Liu X, Zhang L

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2024; (126()):313-318 doi:10.1016/j.jocn.2024.07.005.

Interdisciplinary strategies for diagnosis and treatment of trigeminal neuralgia.

Kolakowski L, Pohl H, Stieglitz L, et al.

Swiss medical weekly 2024; (154()):3460 doi:10.57187/s.3460.

Comparison of treatment results between microvascular decompression and gamma knife radiosurgery in primary trigeminal neuralgia.

Yang MS, Choi CH, Lee JM

Medicine 2024; (103(36)):e39626 doi:10.1097/MD.0000000000039626.

Efficacy and Safety Profile of Gamma Knife Radiosurgery in Classic and Idiopathic Trigeminal Neuralgia.

Goyal-Honavar A, A CK, Dwarakanath S, et al.

World neurosurgery 2024; (192()):e172-e178 doi:10.1016/j.wneu.2024.09.062.

A Retrospective Analysis of Medical Management Strategies for Trigeminal Neuralgia: An Institutional Review.

Murugesan I, T N U, Ramalingam K

Cureus 2024; (16(9)):e69258 doi:10.7759/cureus.69258.

Gamma Knife radiosurgery for relapsing trigeminal neuralgia following microvascular decompression.

Horn AC, Kolahi Sohrabi A, Chan MD, et al.

Journal of neurosurgery 2025; (142(5)):1247-1255 doi:10.3171/2024.7.JNS232274.

Intravenous fosphenytoin therapy for the rescue of acute trigeminal neuralgia crisis in pre- and post-neurosurgical patients: a retrospective observational study.

Noro S, Endo H, Asayama B, et al.

Frontiers in neurology 2024; (15()):1493274 doi:10.3389/fneur.2024.1493274.

Pathogenesis, Diagnosis, and Management of Trigeminal Neuralgia: A Narrative Review.

Liu Y, Tanaka E

Journal of clinical medicine 2025; (14(2)) doi:10.3390/jcm14020528.

From Tics to Stabs: Renaming Cluster Tics in Cluster Headache-A Cross-Sectional Study.

Carney M, Søborg MK, Maarbjerg S, et al.

European journal of neurology 2025; (32(2)):e70053 doi:10.1111/ene.70053.

Hippocampal Subfield Abnormalities in Patients With Primary Trigeminal Neuralgia.

Filimonova E, Pashkov A, Moysak G, et al.

Journal of neuroimaging : official journal of the American Society of Neuroimaging 2025; (35(1)):e70026 doi:10.1111/jon.70026.

In-Hospital Management of Acute Trigeminal Neuralgia Pain Crises.

Chow A, Haider I, Athanaselos A, Patel M

Clinical medicine & research 2024; (22(4)):215-221 doi:10.3121/cmr.2024.1945.

Endoscopic microvascular decompression for primary trigeminal neuralgia: surgical experience and early outcomes.

Feng B, Chai X, Yu Y, et al.

Scientific reports 2025; (15(1)):10289 doi:10.1038/s41598-025-94797-2.

Suicidal Ideation and Self-Injury in Trigeminal Neuralgia.

Fishbein NS, Bakhshaie J, Greenberg J

Journal of pain research 2025; (18()):2003-2010 doi:10.2147/JPR.S493649.

Psychological assessment in patients affected by trigeminal neuralgia. A systematic review.

Martinelli R, Vannuccini S, Burattini B, et al.

Neurosurgical review 2025; (48(1)):414.

The transcription factor Y-box binding protein 3 contributes to mechanical allodynia and anxiety-like behavior in trigeminal neuralgia by transcriptionally triggering period circadian regulator 1 in primary sensory neurons.

Liu D, Wang W, Li H, et al.

International journal of biological macromolecules 2025; (320(Pt 4)):146097 doi:10.1016/j.ijbiomac.2025.146097.

Efficacy of microvascular decompression in the treatment of trigeminal neuralgia: a retrospective Single-Center study of 28 cases.

Krzemińska A, Koźba-Gosztyła M, Bladowska J, Czapiga B

Neurosurgical review 2025; (48(1)):614.

Lidocaine infusion for the treatment of intractable trigeminal neuralgia: retrospective case series and systematic review.

Mohamed MW, Irem-Oko F, Sheikh A, et al.

Acta neurochirurgica 2025; (167(1)):259 doi:10.1007/s00701-025-06672-8.

Reduced volume in the amygdala of trigeminal neuralgia patients: a neuroimaging study with clinical correlates.

Ramos LR, Gama TM, de Mendonça Maia AC, et al.

Experimental brain research 2025; (244(1)):1 doi:10.1007/s00221-025-07191-9.

Short- and Long-Term Pain Relief With Radiofrequency Rhizotomy in Multiple Sclerosis Patients With Trigeminal Neuralgia: A Systematic Review.

Ahmed N, Musa Rabih MR, Fadul Ageeb RM, et al.

Cureus 2025; (17(11)):e97337 doi:10.7759/cureus.97337.

Global Incidence and Prevalence of Trigeminal Neuralgia, 1945-2024: A Systematic Review and Meta-Regression Analysis.

Jeong YD, Jo Y, Son Y, et al.

Journal of clinical neurology (Seoul, Korea) 2026; (22(1)):102-112 doi:10.3988/jcn.2025.0433.

Electrophysiological monitoring of trigeminal nerve sensory root using sensory-masseter response for microvascular decompression in trigeminal neuralgia.

Jiang W, Kang Y, Wan H, et al.

Acta neurochirurgica 2026; (168(1)):13.

Pivotal Factors for Minimizing the Risks of Therapeutic Failure in Trigeminal Neuralgia and Hemifacial Spasm.

Pătrășcan AM, Brehar FM, Gorgan RM

Current pain and headache reports 2026; (30(1)):27 doi:10.1007/s11916-025-01449-1.