Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
Top Authors
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Moorfields Eye Hospital NHS Foundation Trust
London, United Kingdom
Singapore National Eye Center
Singapore, Singapore
National University of Singapore
Singapore, Singapore
Queen's University Belfast
Belfast, United Kingdom
Medical University of Vienna
Vienna, Austria
Université Paris-Est Créteil
Créteil, France
University of Udine
Udine, Italy
The University of Sydney
Sydney, Australia
University of Miami
Coral Gables, United States
University of Bonn
Bonn, Germany
References
References (97)
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Recommended Guidelines for Use of Intravitreal Aflibercept With a Treat-and-Extend Regimen for the Management of Neovascular Age-Related Macular Degeneration in the Asia-Pacific Region: Report From a Consensus Panel.
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Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) 2017; (6(3)):296-302 doi:10.22608/APO.2016125.
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Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration.
Evans JR, Lawrenson JG
The Cochrane database of systematic reviews 2017; (7()):CD000254 doi:10.1002/14651858.CD000254.pub4.
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Relationships of orientation discrimination threshold and visual acuity with macular lesions in age-related macular degeneration.
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Challenges Associated with Estimating Utility in Wet Age-Related Macular Degeneration: A Novel Regression Analysis to Capture the Bilateral Nature of the Disease.
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PREVALENCE OF POLYPOIDAL CHOROIDAL VASCULOPATHY IN WHITE PATIENTS WITH EXUDATIVE AGE-RELATED MACULAR DEGENERATION: Systematic Review and Meta-Analysis.
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EFFICACY AND SAFETY OF INTRAVITREAL AFLIBERCEPT AND RANIBIZUMAB IN ASIAN PATIENTS WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION: Subgroup Analyses From the VIEW Trials.
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Two-Year Risk of Exudation in Eyes with Nonexudative Age-Related Macular Degeneration and Subclinical Neovascularization Detected with Swept Source Optical Coherence Tomography Angiography.
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American journal of ophthalmology 2019; (208()):1-11 doi:10.1016/j.ajo.2019.06.017.
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Optical Coherence Tomography-Angiography of Different Choroidal Neovascularization Subtypes in Wet Age-related Macular Degeneration.
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Oxymetazoline: reduction of subconjunctival hemorrhage incidence after intravitreal injections.
Gonzalez-Saldivar G, Pita-Ortiz IY, Flores-Villalobos EO, et al.
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Anti-Vascular Endothelial Growth Factor Resistance in Exudative Macular Degeneration and Polypoidal Choroidal Vasculopathy.
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TEN-YEAR FOLLOW-UP OF PATIENTS WITH EXUDATIVE AGE-RELATED MACULAR DEGENERATION TREATED WITH INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR INJECTIONS.
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Retina (Philadelphia, Pa.) 2020; (40(9)):1665-1672 doi:10.1097/IAE.0000000000002668.
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Consensus Nomenclature for Reporting Neovascular Age-Related Macular Degeneration Data: Consensus on Neovascular Age-Related Macular Degeneration Nomenclature Study Group.
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Association of Visit Adherence and Visual Acuity in Patients With Neovascular Age-Related Macular Degeneration: Secondary Analysis of the Comparison of Age-Related Macular Degeneration Treatment Trial.
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JAMA ophthalmology 2020; (138(3)):237-242 doi:10.1001/jamaophthalmol.2019.4577.
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Application of Automated Quantification of Fluid Volumes to Anti-VEGF Therapy of Neovascular Age-Related Macular Degeneration.
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Nonexudative Macular Neovascularization - A Systematic Review of Prevalence, Natural History, and Recent Insights from OCT Angiography.
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Ophthalmology. Retina 2020; (4(7)):651-661 doi:10.1016/j.oret.2020.02.016.
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Influence of pigment epithelial detachment on visual acuity in neovascular age-related macular degeneration.
Cheong KX, Teo KYC, Cheung CMG
Survey of ophthalmology 2021; (66(1)):68-97 doi:10.1016/j.survophthal.2020.05.003.
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Rhegmatogenous Retinal Detachment after Intravitreal Injection.
Brown KR, Yannuzzi NA, Smiddy WE, et al.
Ophthalmology. Retina 2021; (5(2)):178-183 doi:10.1016/j.oret.2020.07.007.
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Emerging Therapies in Nonexudative Age-Related Macular Degeneration in 2020.
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Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) 2021; (10(4)):408-416 doi:10.1097/APO.0000000000000355.
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Anti-VEGF crunch syndrome in proliferative diabetic retinopathy: A review.
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Survey of ophthalmology 2021; (66(6)):926-932 doi:10.1016/j.survophthal.2021.03.001.
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Clinical Update on Metamorphopsia: Epidemiology, Diagnosis and Imaging.
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IMPACT OF RESIDUAL SUBRETINAL FLUID VOLUMES ON TREATMENT OUTCOMES IN A SUBRETINAL FLUID-TOLERANT TREAT-AND-EXTEND REGIMEN.
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Retina (Philadelphia, Pa.) 2021; (41(11)):2221-2228 doi:10.1097/IAE.0000000000003180.
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Real-World Safety Outcomes of Intravitreal Ranibizumab Biosimilar (Razumab) Therapy for Chorioretinal Diseases.
Chakraborty D, Stewart MW, Sheth JU, et al.
Ophthalmology and therapy 2021; (10(2)):337-348 doi:10.1007/s40123-021-00345-2.
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RETINAL FLUID AND THICKNESS AS MEASURES OF DISEASE ACTIVITY IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION.
Kaiser PK, Wykoff CC, Singh RP, et al.
Retina (Philadelphia, Pa.) 2021; (41(8)):1579-1586 doi:10.1097/IAE.0000000000003194.
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Mechanisms of sterile inflammation after intravitreal injection of antiangiogenic drugs: a narrative review.
Anderson WJ, da Cruz NFS, Lima LH, et al.
International journal of retina and vitreous 2021; (7(1)):37 doi:10.1186/s40942-021-00307-7.
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Management of neovascular age-related macular degeneration: Taiwan expert consensus.
Yeung L, Hsieh YT, Yang CH, et al.
Journal of the Formosan Medical Association = Taiwan yi zhi 2021; (120(12)):2061-2071 doi:10.1016/j.jfma.2021.06.012.
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Impact of living with a bilateral central vision loss due to geographic atrophy-qualitative study.
Madheswaran G, Ramesh SV, Pardhan S, et al.
BMJ open 2021; (11(7)):e047861 doi:10.1136/bmjopen-2020-047861.
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Diagnostic Accuracy of Monitoring Tests of Fellow Eyes in Patients with Unilateral Neovascular Age-Related Macular Degeneration: Early Detection of Neovascular Age-Related Macular Degeneration Study.
Sivaprasad S, Banister K, Azuro-Blanco A, et al.
Ophthalmology 2021; (128(12)):1736-1747 doi:10.1016/j.ophtha.2021.07.025.
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IMPACT OF FLUID COMPARTMENTS ON FUNCTIONAL OUTCOMES FOR PATIENTS WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION: A Systematic Literature Review.
Chaudhary V, Matonti F, Zarranz-Ventura J, Stewart MW
Retina (Philadelphia, Pa.) 2022; (42(4)):589-606 doi:10.1097/IAE.0000000000003283.
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Fungal Necrotizing Scleritis After Intravitreal Injection Therapy.
Hernández-Pons A, Ortiz-Seller A, López-Cruz I, et al.
Cornea 2021; (40(12)):1617-1619 doi:10.1097/ICO.0000000000002670.
PMID: 34749383 - 55
Efficacy and Safety of Anti-Vascular Endothelial Growth Factor Monotherapies for Neovascular Age-Related Macular Degeneration: A Mixed Treatment Comparison.
Zhang Y, Gao S, Li X, et al.
Frontiers in pharmacology 2021; (12()):797108 doi:10.3389/fphar.2021.797108.
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Age-related macular degeneration: Epidemiology, genetics, pathophysiology, diagnosis, and targeted therapy.
Deng Y, Qiao L, Du M, et al.
Genes & diseases 2022; (9(1)):62-79 doi:10.1016/j.gendis.2021.02.009.
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Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-related macular degeneration (TENAYA and LUCERNE): two randomised, double-masked, phase 3, non-inferiority trials.
Heier JS, Khanani AM, Quezada Ruiz C, et al.
Lancet (London, England) 2022; (399(10326)):729-740 doi:10.1016/S0140-6736(22)00010-1.
PMID: 35085502 - 58
Difference Between the Incidence of Retinal Fluid Subtypes and Their Association with Visual Outcomes According to the Types of Macular Neovascularization in a Korean Population.
Kim JH, Kim JW, Kim CG
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2022; (38(3)):261-268 doi:10.1089/jop.2021.0103.
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Non-invasive testing for early detection of neovascular macular degeneration in unaffected second eyes of older adults: EDNA diagnostic accuracy study.
Banister K, Cook JA, Scotland G, et al.
Health technology assessment (Winchester, England) 2022; (26(8)):1-142 doi:10.3310/VLFL1739.
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Complications of intravitreal injections: 2022.
Patel D, Patel SN, Chaudhary V, Garg SJ
Current opinion in ophthalmology 2022; (33(3)):137-146 doi:10.1097/ICU.0000000000000850.
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Preventive factors, diagnosis, and management of injection-related endophthalmitis: a literature review.
Singh R, Davoudi S, Ness S
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2022; (260(8)):2399-2416 doi:10.1007/s00417-022-05607-8.
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Novel approach to antiangiogenic factors in age-related macular degeneration therapy.
Samelska K, Kupis M, Izdebska J, et al.
Central-European journal of immunology 2022; (47(1)):117-123 doi:10.5114/ceji.2022.113103.
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Long-Term Visual Outcomes in Exudative Age-Related Macular Degeneration Patients With Unanticipated Gaps in Therapy.
Bui YT, Starr MR, Kung FF, et al.
Ophthalmic surgery, lasers & imaging retina 2022; (53(9)):481-489 doi:10.3928/23258160-20220819-02.
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Practical guidance for imaging biomarkers in exudative age-related macular degeneration.
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Survey of ophthalmology 2023; (68(4)):615-627 doi:10.1016/j.survophthal.2023.02.004.
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Chinese Guideline on the Management of Polypoidal Choroidal Vasculopathy (2022).
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Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 2023; (38(2)):77-93 doi:10.24920/004213.
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Influence of lesion location on lesion reactivation after initial treatment in neovascular age-related macular degeneration.
Kim JH, Kim JW, Kim CG
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2023; (261(11)):3139-3148 doi:10.1007/s00417-023-06144-8.
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Clinical Features Associated with Acute Elevated Intraocular Pressure After Intravitreal Anti-VEGF Injections.
LoBue SA, Gindina S, Saba NJ, et al.
Clinical ophthalmology (Auckland, N.Z.) 2023; (17()):1683-1690 doi:10.2147/OPTH.S414212.
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Barriers to care in neovascular age-related macular degeneration: Current understanding, developments, and future directions.
Choi A, Nawash BS, Du K, et al.
Survey of ophthalmology 2024; (69(1)):160-164 doi:10.1016/j.survophthal.2023.09.001.
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Macular neovascularization and polypoidal choroidal vasculopathy: phenotypic variations, pathogenic mechanisms and implications in management.
Cheung CMG
Eye (London, England) 2024; (38(4)):659-667 doi:10.1038/s41433-023-02764-w.
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Mechanistic Insight into Age-Related Macular Degeneration (AMD): Anatomy, Epidemiology, Genetics, Pathogenesis, Prevention, Implications, and Treatment Strategies to Pace AMD Management.
Amini MA, Karbasi A, Vahabirad M, et al.
Chonnam medical journal 2023; (59(3)):143-159 doi:10.4068/cmj.2023.59.3.143.
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Pain control and subconjunctival haemorrhage after intravitreal injection using cooled anaesthetic eyedrops and antiseptics: A prospective, double-blind, randomized controlled trial.
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Acta ophthalmologica 2024; (102(4)):e587-e594 doi:10.1111/aos.15798.
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Improved Structure and Function in Early-Detected Second-Eye Neovascular Age-Related Macular Degeneration: FASBAT/Early Detection of Neovascular Age-Related Macular Degeneration Report 1.
Gale RP, Airody A, Sivaprasad S, et al.
Ophthalmology. Retina 2024; (8(6)):545-552 doi:10.1016/j.oret.2023.12.012.
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Age-Related Macular Degeneration: A Review.
Fleckenstein M, Schmitz-Valckenberg S, Chakravarthy U
JAMA 2024; (331(2)):147-157 doi:10.1001/jama.2023.26074.
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[Quality of life survey of 3,738 patients treated with intravitreal injections for age-related macular degeneration].
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Journal francais d'ophtalmologie 2024; (47(3)):104075 doi:10.1016/j.jfo.2024.104075.
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TENAYA and LUCERNE: Two-Year Results from the Phase 3 Neovascular Age-Related Macular Degeneration Trials of Faricimab with Treat-and-Extend Dosing in Year 2.
Khanani AM, Kotecha A, Chang A, et al.
Ophthalmology 2024; (131(8)):914-926 doi:10.1016/j.ophtha.2024.02.014.
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RAHNELLA AQUATILIS ENDOPHTHALMITIS AFTER INTRAVITREAL INJECTION IN AN IMMUNOCOMPETENT PATIENT.
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Retinal cases & brief reports 2025; (19(3)):311-314 doi:10.1097/ICB.0000000000001567.
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Intravitreal aflibercept 8 mg in neovascular age-related macular degeneration (PULSAR): 48-week results from a randomised, double-masked, non-inferiority, phase 3 trial.
Lanzetta P, Korobelnik JF, Heier JS, et al.
Lancet (London, England) 2024; (403(10432)):1141-1152 doi:10.1016/S0140-6736(24)00063-1.
PMID: 38461841 - 78
Home-monitoring for neovascular age-related macular degeneration in older adults within the UK: the MONARCH diagnostic accuracy study.
Hogg RE, Wickens R, O'Connor S, et al.
Health technology assessment (Winchester, England) 2024; (28(32)):1-136 doi:10.3310/CYRA9912.
PMID: 39023220 - 79
Recent Updates on the Diagnosis and Management of Age-Related Macular Degeneration.
Boopathiraj N, Wagner IV, Dorairaj SK, et al.
Mayo Clinic proceedings. Innovations, quality & outcomes 2024; (8(4)):364-374 doi:10.1016/j.mayocpiqo.2024.05.003.
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Survey of ophthalmology 2025; (70(4)):653-675 doi:10.1016/j.survophthal.2024.08.003.
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Reactivation of stable neovascular age-related macular degeneration following treat-and-extend regimen discontinuation.
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Clinical & experimental ophthalmology 2025; (53(1)):76-83 doi:10.1111/ceo.14444.
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Global Insights from Patients, Providers, and Staff on Challenges and Solutions in Managing Neovascular Age-Related Macular Degeneration.
Loewenstein A, Sylvanowicz M, Amoaku WM, et al.
Ophthalmology and therapy 2025; (14(1)):211-228 doi:10.1007/s40123-024-01061-3.
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The Past, Present, and Future Perspective of Photodynamic Therapy for Age-Related Macular Degeneration.
Honda S
Journal of clinical medicine 2025; (14(4)) doi:10.3390/jcm14041240.
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Comparative efficacy of intravitreal anti-VEGF therapy for neovascular age-related macular degeneration: A systematic review with network meta-analysis.
Butler ETS, Arnold-Vangsted A, Schou MG, et al.
Acta ophthalmologica 2025; (103(7)):741-763 doi:10.1111/aos.17506.
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Intravitreal anti-vascular endothelial growth factor injections and risks of stroke in patients with neovascular age-related macular degeneration-A registry-based cohort study.
Falemban AH, Söderberg-Löfdal K, Jonsson F, et al.
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