Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
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The Royal Free Hospital
London, United Kingdom
Mayo Clinic
Rochester, United States
Inserm
Paris, France
Pfizer (United States)
New York, United States
Amyloidosis Foundation
Clarkston, United States
Columbia University Irving Medical Center
New York, United States
Boston University
Boston, United States
British Heart Foundation
London, United Kingdom
Alnylam Pharmaceuticals (United States)
Cambridge, United States
Brigham and Women's Hospital
Boston, United States
References
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Utility of Neuropathy Screening for Wild-Type Transthyretin Amyloidosis Patients.
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Same same, but different? The neurological presentation of wildtype transthyretin (ATTRwt) amyloidosis.
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A Case of Wild-type Cardiac Transthyretin Amyloidosis Diagnosed by Non-invasive Methods.
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Identification of wild-type transthyretin cardiac amyloidosis in patients with carpal tunnel syndrome surgery (CACTuS).
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Skeletal muscle 99mTechnetium-pyrophosphate scan: More questions than answers.
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Muscle & nerve 2023; (67(2)):98-100 doi:10.1002/mus.27754.
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Wild type cardiac amyloidosis: is it time to order a nuclear technetium pyrophosphate SPECT imaging study?
Shen CP, Vanichsarn CT, Pandey AC, et al.
The international journal of cardiovascular imaging 2023; (39(1)):201-208 doi:10.1007/s10554-022-02692-y.
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Case Report and Literature Review of Cardiac Amyloidosis: A Not-So-Rare Cause of Heart Failure.
Baptista P, Moura de Azevedo S, Alexandre A, Dias-Frias A
Cureus 2023; (15(1)):e33364 doi:10.7759/cureus.33364.
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ESC heart failure 2023; (10(3)):1871-1882 doi:10.1002/ehf2.14350.
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Amyloidosis of the Heart: A Comprehensive Review.
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Cureus 2023; (15(2)):e35264 doi:10.7759/cureus.35264.
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Clinical characteristics and prognostic implications of orthopedic ligament disorders in patients with wild-type transthyretin amyloidosis cardiomyopathy.
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Emerging Role of Scintigraphy Using Bone-Seeking Tracers for Diagnosis of Cardiac Amyloidosis: AJR Expert Panel Narrative Review.
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The Emerging Significance of Amyloid Deposits in the Ligamentum Flavum of Spinal Stenosis Patients: A Review.
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A simple ATTR-CM score to identify transthyretin amyloid cardiomyopathy burden in HFpEF patients.
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European journal of clinical investigation 2023; (53(11)):e14045 doi:10.1111/eci.14045.
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Characteristics of Carpal Tunnel Syndrome in Wild-Type Transthyretin Amyloidosis.
Russell A, Khayambashi S, Fine NM, et al.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2024; (51(4)):482-486 doi:10.1017/cjn.2023.268.
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Insights Regarding the Article "Exploring Transthyretin Amyloid Cardiomyopathy: A Comprehensive Review of the Disease and Upcoming Treatments".
Sandeep B, Ma C, Chen J, Xiao Z
Current problems in cardiology 2024; (49(1 Pt B)):102100 doi:10.1016/j.cpcardiol.2023.102100.
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Tafamidis in patients with severe heart failure due to transthyretin amyloidosis cardiomyopathy: Improved long-term survival.
Tubben A, Nienhuis HLA, van der Meer P
European journal of heart failure 2023; (25(11)):2065-2066 doi:10.1002/ejhf.3053.
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Tafamidis Efficacy Among Octogenarian Patients in the Phase 3 ATTR-ACT and Ongoing Long-Term Extension Study.
Garcia-Pavia P, Sultan MB, Gundapaneni B, et al.
JACC. Heart failure 2024; (12(1)):150-160 doi:10.1016/j.jchf.2023.08.032.
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Prevalence of transthyretin amyloidosis in patients undergoing carpal tunnel surgery: a prospective cohort study and risk factor analysis.
Brunet J, Rabarin F, Maugendre E, et al.
The Journal of hand surgery, European volume 2024; (49(8)):1002-1007 doi:10.1177/17531934231218997.
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Efficacy and Safety of Acoramidis in Transthyretin Amyloid Cardiomyopathy.
Gillmore JD, Judge DP, Cappelli F, et al.
The New England journal of medicine 2024; (390(2)):132-142 doi:10.1056/NEJMoa2305434.
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Current barriers and recommendations on the diagnosis of transthyretin amyloid cardiomyopathy: a Delphi study.
Çavuşoğlu Y, Başarıcı İ, Tüfekçioğlu O, et al.
Frontiers in cardiovascular medicine 2024; (11()):1299261 doi:10.3389/fcvm.2024.1299261.
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Neuromuscular manifestations of wild type transthyretin amyloidosis: a review and single center's experience.
Živković SA, Lacomis D, Soman P
Frontiers in cardiovascular medicine 2024; (11()):1345608 doi:10.3389/fcvm.2024.1345608.
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Real-World Effectiveness of High-Dose Tafamidis on Neurologic Disease Progression in Mixed-Phenotype Variant Transthyretin Amyloid Cardiomyopathy.
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Cardiology and therapy 2024; (13(2)):359-368 doi:10.1007/s40119-024-00362-9.
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Cardiac Biomarker Change at 1 Year After Tafamidis Treatment and Clinical Outcomes in Patients With Transthyretin Amyloid Cardiomyopathy.
Kuyama N, Takashio S, Oguni T, et al.
Journal of the American Heart Association 2024; (13(10)):e034518 doi:10.1161/JAHA.124.034518.
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Single German centre experience with patient journey and care-relevant needs in amyloidosis: The German AMY-NEEDS research and care program.
Ihne-Schubert SM, Leberzammer M, Weidgans M, et al.
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Cardiovascular autonomic failure in hereditary transthyretin amyloidosis and TTR carriers is an early and progressive disease marker.
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The Role of Scintigraphy with Bone Radiotracers in Cardiac Amyloidosis.
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Heart failure clinics 2024; (20(3)):307-316 doi:10.1016/j.hfc.2024.03.003.
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Tafamidis in the Treatment of ATTR-related Cardiomyopathy: Indications and Grey Zones.
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Expansion of the National Amyloidosis Centre staging system to detect early mortality in transthyretin cardiac amyloidosis.
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European journal of heart failure 2024; (26(9)):2008-2012 doi:10.1002/ejhf.3354.
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Response to therapy with tafamidis 61 mg in patients with cardiac transthyretin amyloidosis: real-world experience since approval.
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Age- and Sex-Related Differences in Patients With Wild-Type Transthyretin Amyloidosis: Insights From THAOS.
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JACC. Advances 2024; (3(8)):101086 doi:10.1016/j.jacadv.2024.101086.
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Health-related quality of life is an independent predictor of mortality and hospitalisations in transthyretin amyloid cardiomyopathy: a prospective cohort study.
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Transthyretin amyloid cardiomyopathy: Literature review and red-flag symptom clusters for each cardiology specialty.
Izumiya Y, Kubo T, Endo J, et al.
ESC heart failure 2025; (12(2)):955-967 doi:10.1002/ehf2.15016.
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Vutrisiran in Patients with Transthyretin Amyloidosis with Cardiomyopathy.
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The New England journal of medicine 2025; (392(1)):33-44 doi:10.1056/NEJMoa2409134.
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Contextualizing the results of HELIOS-B in the broader landscape of clinical trials for the treatment of transthyretin cardiac amyloidosis.
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Role of biomarkers in early diagnosis and prognosis of cardiac amyloidosis: A systematic review and meta-analysis.
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The journey to diagnosis of wild-type transthyretin-mediated (ATTRwt) amyloidosis: a path with multisystem involvement.
Karam C, Moffit C, Summers C, et al.
Orphanet journal of rare diseases 2024; (19(1)):419 doi:10.1186/s13023-024-03407-3.
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From Molecular to Radionuclide and Pharmacological Aspects in Transthyretin Cardiac Amyloidosis.
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International journal of molecular sciences 2024; (26(1)) doi:10.3390/ijms26010146.
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Guideline-Directed Medical Therapy for Heart Failure in Transthyretin Amyloid Cardiomyopathy.
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Cardiac amyloidosis after lumbar spinal stenosis surgery - a comprehensive prospective cohort study.
Eldhagen P, Tzortzakakis A, Lund LH, et al.
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Early cardiovascular autonomic failure in ATTRv predicts poor prognosis and may respond to disease-modifying therapy.
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High-Sensitivity Cardiac Troponin I for Risk Stratification in Wild-Type Transthyretin Amyloid Cardiomyopathy.
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Differential Binding Affinities and Kinetics of Transthyretin Stabilizers.
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Journal of cardiovascular pharmacology 2025; doi:10.1097/FJC.0000000000001726.
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Transthyretin Amyloid Cardiomyopathy-2025 Update: Current Diagnostic Approaches and Emerging Therapeutic Options.
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Journal of clinical medicine 2025; (14(13)) doi:10.3390/jcm14134785.
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Tafamidis: A game changer in transthyretin cardiomyopathy? A systematic review and meta-analysis of safety and efficacy.
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Transthyretin Kinetic Stabilizers for ATTR Amyloidosis: A Narrative Review of Mechanisms and Therapeutic Benefits.
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Longitudinal Changes in Multiple Cardiac Biomarkers in Transthyretin Amyloidosis Cardiomyopathy Patients Treated Vs Untreated with Tafamidis.
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Non-amyloid specific treatment for transthyretin cardiac amyloidosis: a clinical consensus statement of the ESC Heart Failure Association.
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