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Maternal-Fetal Medicine · Spina Bifida

Does Open Fetal Surgery Affect Future Pregnancies?

At a Glance

Open fetal surgery for spina bifida requires an incision that leaves a permanent uterine scar. Due to the risk of uterine rupture, patients must wait 18 to 24 months before conceiving again and all future pregnancies must be delivered via scheduled C-section before natural labor begins.

Yes, open fetal surgery for spina bifida does impact your ability to manage future pregnancies. Balancing the health of your current baby with your hopes for future children is an incredibly heavy decision to make. Because the procedure involves making an incision through the wall of your uterus (a hysterotomy) to reach the baby, it leaves a permanent scar. While many women go on to have healthy pregnancies after fetal surgery, this scar means that all future pregnancies—and the delivery of your current baby—will require specialized monitoring and a different delivery plan.

The Uterine Scar and Healing

During open fetal surgery, the surgeon typically makes a “classical” or vertical incision in the active, contracting part of the uterus. This is different from the lower, horizontal incision used in most routine C-sections.

As a result, the scar left behind carries a significant risk of uterine dehiscence (where the scar begins to separate or thin out) or uterine rupture (where the scar opens) during a future pregnancy [1][2]. Research indicates that the risk of the scar separating in pregnancies following open fetal surgery is similar to the risk seen in women who have had a classical C-section [1].

Because classical scars can be unpredictable as they stretch, your future pregnancies will need to be closely followed by a maternal-fetal medicine specialist. Your doctor will use advanced ultrasound to monitor your uterus and ensure you and your baby remain safe.

Waiting Period Before Conceiving Again

If you undergo open fetal surgery, you must wait a specific healing period before trying to conceive your next child [3]. Getting pregnant before the uterine tissue has fully healed can increase the risk of complications.

While there is no single universal timeline for exactly how many months you must wait [4], your surgical team will give you a personalized recommendation. They will usually advise waiting an extended period (often 18 to 24 months, or longer) to ensure your uterus has had maximal time to recover. It is highly recommended to consult your maternal-fetal medicine specialist for a preconception assessment before you start trying to conceive again.

Delivery of Future Pregnancies

To keep you and your future babies safe, your medical team will change how you deliver. Because the strong contractions of natural labor put physical stress on the uterus, laboring with a classical hysterotomy scar is not considered safe [2].

Therefore, all future pregnancies must be delivered by a scheduled C-section before the onset of natural labor [1][2]. By scheduling the delivery early—typically around 36 to 37 weeks, before natural labor might begin—your care team ensures that you do not experience the strong contractions that could put stress on your scar. (Note: This also applies to your current pregnancy; your baby will be delivered via a scheduled C-section after the fetal surgery.)

(Note: Newer, minimally invasive approaches like fetoscopic repair are being studied and may offer a lower risk of uterine dehiscence compared to open surgery, though they carry their own unique risks [5]. Your eligibility for these alternatives depends on your specific medical situation.)

Common questions in this guide

Will I have to deliver by C-section after open fetal surgery?
Yes. Because the surgery leaves a classical vertical scar on your uterus, the strong contractions of natural labor are not safe. To prevent the scar from opening, all future pregnancies must be delivered by a scheduled C-section before labor starts, usually around 36 to 37 weeks.
How long do I need to wait to get pregnant again after fetal surgery?
Your medical team will give you a personalized recommendation, but you will typically need to wait 18 to 24 months before trying to conceive. This extended waiting period ensures your uterine tissue has maximal time to heal, reducing the risk of complications in your next pregnancy.
What are the risks to my uterus in future pregnancies?
The primary risk is that the classical uterine scar could thin out (uterine dehiscence) or completely separate (uterine rupture) as your uterus stretches. Because of this risk, your future pregnancies will require close monitoring by a maternal-fetal medicine specialist.
Can minimally invasive fetal surgery reduce my future pregnancy risks?
Minimally invasive fetoscopic repair may offer a lower risk of uterine scar separation compared to open surgery. However, it carries its own unique risks and is not suitable for everyone, so your doctor will determine if you are a candidate based on your specific medical situation.

Questions to Ask Your Doctor

Curated prompts to bring to your next appointment.

  1. 1.What is the specific waiting period you recommend for me before trying to conceive another child?
  2. 2.Am I a candidate for minimally invasive fetoscopic repair rather than open surgery, and how does that change my future pregnancy risks?
  3. 3.What signs or symptoms should I watch for in future pregnancies that might indicate an issue with my uterine scar?
  4. 4.At how many weeks will my scheduled C-sections typically take place for my current and future pregnancies?
  5. 5.Who will manage my prenatal care for future pregnancies, and what specific monitoring will I need?

Questions For You

Tap a prompt to share your answer — we'll use it plus this page's context to start a tailored conversation.

References

References (5)
  1. 1

    Subsequent pregnancy outcomes after open maternal-fetal surgery for myelomeningocele.

    Goodnight WH, Bahtiyar O, Bennett KA, et al.

    American journal of obstetrics and gynecology 2019; (220(5)):494.e1-494.e7 doi:10.1016/j.ajog.2019.03.008.

    PMID: 30885769
  2. 2

    Subsequent Pregnancy Outcomes after Open in utero Spina Bifida Repair.

    Zepf J, Vonzun L, Krähenmann F, et al.

    Fetal diagnosis and therapy 2022; (49(9-10)):442-450 doi:10.1159/000527813.

    PMID: 36455544
  3. 3

    Anesthesia for Maternal-Fetal Interventions: A Consensus Statement From the American Society of Anesthesiologists Committees on Obstetric and Pediatric Anesthesiology and the North American Fetal Therapy Network.

    Chatterjee D, Arendt KW, Moldenhauer JS, et al.

    Anesthesia and analgesia 2021; (132(4)):1164-1173 doi:10.1213/ANE.0000000000005177.

    PMID: 33048913
  4. 4

    Benefits and complications of fetal and postnatal surgery for open spina bifida: systematic review and proportional meta-analysis.

    Kunpalin Y, Karadjole VS, Medeiros ESB, et al.

    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2025; (66(2)):135-146 doi:10.1002/uog.29240.

    PMID: 40492626
  5. 5

    Fetal Surgery for Myelomeningocele: A Systematic Review and Meta-Analysis of Outcomes in Fetoscopic versus Open Repair.

    Kabagambe SK, Jensen GW, Chen YJ, et al.

    Fetal diagnosis and therapy 2018; (43(3)):161-174 doi:10.1159/000479505.

    PMID: 28910784

This page provides general information about how fetal surgery may impact future pregnancies. It does not replace professional medical advice; always consult your maternal-fetal medicine specialist to discuss your individual family planning and health risks.

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