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Orthopedics

Why Does MO Cause Bone Deformities & Uneven Leg Length?

At a Glance

Multiple osteochondromas (MO) cause bone deformities because the bone bumps act like anchors near active growth plates, restricting normal growth. This uneven growth leads to forearm bowing, knock-knees, and uneven leg lengths. These changes stop progressing once a child reaches skeletal maturity.

It can be startling to notice changes in the shape of your child’s arms or legs, but forearm bowing and leg length differences are very common, classic features of multiple osteochondromas (MO) [1]. The short answer is that the bone bumps (osteochondromas) develop near the growth plates and act like physical anchors, slowing down bone growth in certain areas [1][2].

Imagine a young tree trying to grow upward, but a heavy wire is tied to one side of the trunk. As the tree grows, the restricted side cannot keep up with the free side, causing the entire trunk to curve. In a similar way, when an osteochondroma forms at the growth plate, it “tethers” the bone, leading to bowing, shortening, or angled growth like knock-knees [1][3][2].

Because these deformities are driven by active growth plates, it is reassuring to know that the bowing and lengthening differences will stop progressing once your child reaches skeletal maturity (when they finish growing and their growth plates close) [4][1].

Why the Forearm Bows (Ulnar Shortening)

The forearm is made up of two parallel bones: the ulna (on the pinky side) and the radius (on the thumb side). In MO, osteochondromas frequently form at the bottom of the ulna near the wrist, slowing its growth [5][6]. Because the two bones are connected by ligaments, problems arise when they grow at different speeds.

While the ulna’s growth is stunted by the osteochondroma, the radius continues to grow at a more normal pace [7][8]. Because the radius has nowhere straight to go, it begins to bend and bow outward to accommodate its extra length [7][8][9]. Over time, this uneven growth can push the top of the radius out of its normal position at the elbow, a condition called radial head dislocation [7][9].

How it feels: This is not just a cosmetic change. This bowing and dislocation can physically block the joint, making it difficult for the child to fully rotate their forearm (turning the palm up or down, known as supination and pronation) [10][7].

Leg Length Discrepancies and Ankle Angling

The bones of the legs grow the fastest, particularly around the knee. When osteochondromas develop near these highly active growth plates, they can interfere with normal, straight bone lengthening [1][11].

If the bumps affect the growth plates in one leg more than the other, that leg will grow more slowly, eventually leading to a noticeable difference in leg length [1][3][11]. This might cause a noticeable limp or back pain.

A similar tethering “race” happens in the lower leg. The lower leg has two bones: the tibia (shinbone) and the fibula. Osteochondromas often stunt the fibula, and as the tibia keeps growing, it causes the ankle to angle outward (ankle valgus) [5][1].

Knock-Knees (Genu Valgum)

Another common result of uneven growth is “knock-knees” (medically known as genu valgum). This happens when an osteochondroma acts as a tether on just one side of the knee’s growth plate [2][12]. If the outer edge of the growth plate is restricted while the inner edge continues to grow normally, the leg will begin to angle inward toward the other knee [1][3][2].

What Can Be Done?

Understanding why these changes happen is the first step, but it is also important to know that orthopedic specialists have a step-by-step approach to managing these deformities, starting with the least invasive options:

  • Monitoring: Regular X-rays (typically every 6 to 12 months) help doctors track the growth plates, measure differences in bone length, and check the alignment of joints [13][14].
  • Shoe Lifts: For mild to moderate leg length discrepancies, a simple insert or lift added to the child’s shoe can level the hips, improve their gait, and prevent back pain without any surgery [5][15].
  • Early Removal: Sometimes, carefully removing an osteochondroma that is acting as a tether can relieve the tension [2][12]. However, simply removing the bump does not always guarantee the growth plate will correct its trajectory on its own, so it is often combined with other procedures [16].
  • Guided Growth: For angled deformities like knock-knees, doctors can perform a minor procedure (such as placing a small plate or staple) on the faster-growing side of the growth plate. This temporarily slows it down, allowing the slower side to catch up and straighten the leg [17][18].
  • Bone Lengthening: In severe cases where the ulna becomes extremely short or a leg length difference is very large, complex surgical techniques can be used to gradually lengthen the bone [19][20]. Because this is a major intervention, it is generally reserved for situations where the deformity causes significant functional problems.

Common questions in this guide

Why do multiple osteochondromas cause bone deformities?
Osteochondromas often develop near active growth plates and act like physical anchors. This "tethers" the bone, slowing down growth on one side and causing the bone to bow, shorten, or angle as the rest of the bone continues trying to grow.
Will the bone bowing and leg length differences keep getting worse?
These deformities are driven by active growth plates. Reassuringly, once your child reaches skeletal maturity and their growth plates close, the bowing and leg length differences will stop progressing.
What causes forearm bowing in multiple osteochondromas?
Bumps often form on the ulna bone near the wrist, stunting its growth. The parallel radius bone continues to grow normally but has nowhere straight to go, causing it to bend outward and sometimes dislocate at the elbow.
How are leg length discrepancies treated without surgery?
For mild to moderate differences in leg length, doctors often recommend adding a simple shoe lift. This insert helps level the hips, improves the child's walking gait, and can prevent back pain without the need for surgery.
Can removing the osteochondroma fix the bone angle?
Carefully removing a bump that is tethering a growth plate can relieve tension. However, simply removing it does not guarantee the bone will straighten on its own, so it is often combined with procedures like guided growth.

Questions to Ask Your Doctor

Curated prompts to bring to your next appointment.

  1. 1.Based on their current bone age, how much remaining growth potential does my child have?
  2. 2.How much of a leg length difference is acceptable before we need to intervene?
  3. 3.Could my child benefit from a simple shoe lift to help with their gait or back alignment?
  4. 4.Are there specific activities or sports my child should avoid if they have forearm bowing or a leg length difference?
  5. 5.If we surgically remove a bump that is tethering a growth plate, will my child also need guided growth to correct the angle?

Questions For You

Tap a prompt to share your answer — we'll use it plus this page's context to start a tailored conversation.

References

References (20)
  1. 1

    Identification of a novel EXT2 frameshift mutation in a family with hereditary multiple exostoses by whole-exome sequencing.

    Yang M, Xie H, Xu B, et al.

    Journal of clinical laboratory analysis 2021; (35(9)):e23968 doi:10.1002/jcla.23968.

    PMID: 34403521
  2. 2

    Rare phenotype of juxtaepiphyseal osteochondroma of the proximal phalanx and its management: A case report.

    Vanapalli R, Mlv SK, Ansari MT

    World journal of clinical cases 2025; (13(24)):106459 doi:10.12998/wjcc.v13.i24.106459.

    PMID: 40862191
  3. 3

    Total knee arthroplasty in patients with multiple hereditary exostoses.

    Fernandez-Perez SA, Rodriguez JA, Beaton-Comulada D, et al.

    Arthroplasty today 2018; (4(3)):325-329 doi:10.1016/j.artd.2017.11.008.

    PMID: 30186915
  4. 4

    The natural history of multiple osteochondromas in a large Italian cohort of pediatric patients.

    Mordenti M, Shih F, Boarini M, et al.

    Bone 2020; (139()):115499 doi:10.1016/j.bone.2020.115499.

    PMID: 32592948
  5. 5

    Hereditary multiple exostoses: are there new plausible treatment strategies?

    Pacifici M

    Expert opinion on orphan drugs 2018; (6(6)):385-391 doi:10.1080/21678707.2018.1483232.

    PMID: 31448184
  6. 6

    Endoscopic endonasal extreme far-medial approach for a lower clivus osteochondroma in a patient with hereditary multiple exostoses: illustrative case.

    Morinaga Y, Akutsu H, Kino H, et al.

    Journal of neurosurgery. Case lessons 2021; (1(20)):CASE2153 doi:10.3171/CASE2153.

    PMID: 35855014
  7. 7

    An Evaluation of Forearm Deformities in Hereditary Multiple Exostoses: Factors Associated With Radial Head Dislocation and Comprehensive Classification.

    Jo AR, Jung ST, Kim MS, et al.

    The Journal of hand surgery 2017; (42(4)):292.e1-292.e8 doi:10.1016/j.jhsa.2017.01.010.

    PMID: 28249791
  8. 8

    Forearm Deformity and Radial Head Dislocation in Pediatric Patients with Hereditary Multiple Exostoses: A Prospective Study Using Proportional Ulnar Length as a Scale to Lengthen the Shortened Ulna.

    Huang P, Zhu L, Ning B

    The Journal of bone and joint surgery. American volume 2020; (102(12)):1066-1074 doi:10.2106/JBJS.19.01444.

    PMID: 32221177
  9. 9

    Gradual ulnar lengthening in children with multiple exostoses and radial head dislocation: results at skeletal maturity.

    D'Ambrosi R, Barbato A, Caldarini C, et al.

    Journal of children's orthopaedics 2016; (10(2)):127-33 doi:10.1007/s11832-016-0718-8.

    PMID: 26910403
  10. 10

    Forearm lengthening: management of elbow and wrist.

    Launay F, Pesenti S

    Journal of children's orthopaedics 2016; (10(6)):593-595 doi:10.1007/s11832-016-0786-9.

    PMID: 27826904
  11. 11

    Total Knee Arthroplasty With Patient-Specific Instrumentation to Correct Severe Valgus Deformity in a Patient With Hereditary Multiple Exostoses.

    Sasaki U, Tamaki M, Tomita T, Okada S

    Arthroplasty today 2022; (16()):175-181 doi:10.1016/j.artd.2022.04.017.

    PMID: 35789783
  12. 12

    Development of genu valgum after removal of osteochondromas from the proximal tibia.

    Denduluri SK, Lu M, Bielski RJ

    Journal of pediatric orthopedics. Part B 2016; (25(6)):582-6 doi:10.1097/BPB.0000000000000221.

    PMID: 26317827
  13. 13

    Radiographic Analysis of the Pediatric Hip Patients With Hereditary Multiple Exostoses (HME).

    Duque Orozco MDP, Abousamra O, Rogers KJ, Thacker MM

    Journal of pediatric orthopedics 2018; (38(6)):305-311 doi:10.1097/BPO.0000000000000815.

    PMID: 27328120
  14. 14

    Guided Growth Improves Coxa Valga and Hip Subluxation in Children With Hereditary Multiple Exostoses.

    Hung TY, Wu KW, Lee CC, et al.

    Journal of pediatric orthopedics 2023; (43(1)):e67-e73 doi:10.1097/BPO.0000000000002296.

    PMID: 36509457
  15. 15

    Pediatric Synovial Osteochondromatosis of the Knee with Leg Length Discrepancy: A Case Report.

    Shimizu J, Fujita H, Suzuki T, et al.

    Journal of orthopaedic case reports 2024; (14(3)):39-43 doi:10.13107/jocr.2024.v14.i03.4280.

    PMID: 38560319
  16. 16

    Treatment strategies for osteochondromas in the distal ulna - a multicentre comparative cohort study.

    Libberecht K, Neergård Sletten I, Shafie L, et al.

    The Journal of hand surgery, European volume 2026; (51(3)):270-281 doi:10.1177/17531934251382725.

    PMID: 41137401
  17. 17

    Outcomes of Temporary Hemiepiphyseal Stapling for Correcting Genu Valgum in Children with Multiple Osteochondromas: A Single Institution Study.

    Trisolino G, Boarini M, Mordenti M, et al.

    Children (Basel, Switzerland) 2021; (8(4)) doi:10.3390/children8040287.

    PMID: 33917765
  18. 18

    Planned Realignment Osteotomies Ahead of Knee Arthroplasty for Pronounced Joint Malalignment: A Case Report in Hereditary Multiple Exostoses Disease.

    Schmid T, Schmid M, Schai PA

    Arthroplasty today 2024; (30()):101519 doi:10.1016/j.artd.2024.101519.

    PMID: 39559546
  19. 19

    Ulnar lengthening for children with forearm deformity from hereditary multiple exostoses: a retrospective study from a tertiary medical center.

    Wang S, Herman B, Wu Y, et al.

    BMC pediatrics 2024; (24(1)):585 doi:10.1186/s12887-024-05063-9.

    PMID: 39285333
  20. 20

    Modified ulnar lengthening for correction of the Masada type 2 forearm deformity in hereditary multiple exostosis.

    Cao S, Zeng JF, Xiao S, et al.

    Scientific reports 2023; (13(1)):10554 doi:10.1038/s41598-023-37532-z.

    PMID: 37386285

This page provides educational information about bone growth in multiple osteochondromas. Always consult a pediatric orthopedic specialist for an accurate assessment of your child's specific deformities and treatment options.

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