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Orthopedic Oncology

Why See an Oncologist for Multiple Osteochondromas?

At a Glance

An orthopedic oncologist specializes in all bone and cartilage tumors, including benign multiple osteochondromas. They are the most qualified doctors to monitor your bone bumps, perform complex surgeries to relieve pain or nerve pressure, and detect rare but serious changes early.

Hearing that you are being referred to an “oncologist” is terrifying, especially when you have been told that your multiple osteochondromas are benign (non-cancerous) bone bumps. It is completely normal to feel panicked by this referral. However, an orthopedic oncologist is simply a surgeon who specializes in tumors of the bone and cartilage—both benign and malignant. Because multiple osteochondromas is a complex condition characterized by multiple bone growths, an orthopedic oncologist is the most qualified specialist to manage your care. They are uniquely trained to monitor the structural details of your bumps, perform complex removals if they start pressing on nerves or blood vessels, and keep a watchful eye out for the rare instances when a bump turns into something dangerous. During your first visit, your oncologist will likely establish a “baseline” by taking X-rays or MRIs of your current bumps, giving them a map to compare against in the future.

The Ultimate Experts in Bone and Cartilage

Every osteochondroma has a layer of cartilage on top of it, known as the cartilage cap. The health and thickness of this cap is one of the most important factors in monitoring your condition.

Because cartilage does not show up well on standard X-rays, evaluating it requires advanced imaging like an MRI [1][2]. Orthopedic oncologists are experts at reading these scans and precisely measuring the cartilage cap. In adults, if the cartilage cap grows thicker than 2 centimeters, it acts as an important warning sign that the bump requires closer investigation [3][4][5]. Note that in growing children, the cartilage cap is naturally thicker, so pediatric thresholds for concern are different [1][6].

Surveillance for Malignant Transformation

While the vast majority of osteochondromas remain completely benign for your entire life, people with multiple osteochondromas have a 1% to 10% lifetime risk of a benign bump transforming into a type of bone cancer called secondary chondrosarcoma [7][8][9]. This risk is higher than it is for someone who only has a single isolated osteochondroma [8][10]. You may wonder why this percentage range is so broad; this largely reflects differences across various medical studies and the rarity of the condition, though researchers continue to study whether specific genetic mutations influence individual risk [7][11].

Because of this risk, your care requires a doctor with a high index of suspicion who knows exactly what “red flags” to look for [4][12]. Rather than relying on frequent full-body scans—which are not standard practice—your oncologist will base your monitoring schedule on your specific symptoms and use targeted imaging on high-risk areas [13][14]. They actively monitor you for clinical signs of a changing bump, such as:

  • New or worsening pain in a bump that used to be painless [15][3][16]
  • Any new growth of a bump after you have reached adulthood and stopped growing, or rapid growth during childhood [15][3][16]
  • Pain that wakes you up at night or occurs when you are resting

They do not just wait for a problem to occur; their specialized training ensures that if a bump does start to change, it is caught and investigated as early as possible.

Safely Navigating Complex Surgeries

Even when they are entirely benign, osteochondromas sometimes need to be surgically removed. This is usually because a bump has grown large enough to press against nearby nerves or blood vessels, or because it is physically blocking a joint from moving properly [17][18][19].

When bumps are located in flat bones or tricky anatomical locations—like the pelvis, spine, or deep inside the hip or shoulder joints—surgery becomes highly complex [20][21][22]. Orthopedic oncologists are the surgeons best equipped to handle these high-stakes removals.

They use advanced surgical techniques, sometimes completely removing the bump and its base in one single piece (a technique called en bloc resection) [20][21][22]. This thorough approach cleanly separates the bump from the normal bone surface—without removing large segments of your healthy, native bone—which helps prevent the bump from growing back while safely protecting your critical nerves and blood vessels. Additionally, because multiple osteochondromas can cause bones to bend or grow at different lengths, orthopedic oncologists are skilled at complex reconstructive surgeries, like limb lengthening and bone-straightening procedures, to help you maintain your mobility [23][24][25].

Ultimately, an orthopedic oncologist is a highly specialized, lifelong partner dedicated to preserving your mobility, treating complications, and providing the peace of mind that comes from expert surveillance [26][8][27].

Common questions in this guide

Why do I need to see an oncologist for benign bone bumps?
Orthopedic oncologists specialize in all tumors of the bone and cartilage, not just cancer. They are uniquely trained to monitor complex bone growths, perform safe surgical removals, and detect any rare, dangerous changes early.
What is a cartilage cap and why is it important?
Every osteochondroma has a layer of cartilage on top called the cartilage cap. If this cap grows thicker than 2 centimeters in an adult, it acts as an early warning sign that the bump requires closer medical investigation.
Can multiple osteochondromas turn into cancer?
While the vast majority of bumps remain benign, people with multiple osteochondromas have a 1% to 10% lifetime risk of a bump transforming into secondary chondrosarcoma, a type of bone cancer. Routine monitoring helps catch these rare changes early.
When should I contact my doctor about a changing bump?
You should contact your doctor immediately if you notice new or worsening pain, pain that wakes you up at night, or any new growth or sudden changes in a bump's size or shape after you have reached adulthood.
How is an osteochondroma surgically removed?
Orthopedic oncologists often use a technique called en bloc resection to remove the bump and its base in one piece. This protects nearby nerves, blood vessels, and healthy bone while helping to prevent the bump from growing back.

Questions to Ask Your Doctor

Curated prompts to bring to your next appointment.

  1. 1.Given my specific bumps, which ones do you want to monitor most closely and how often?
  2. 2.Should I be getting baseline MRIs of certain areas like my hips or pelvis to map my current bumps?
  3. 3.What specific 'red flag' symptoms should prompt me to call your office immediately?
  4. 4.If I eventually need a bump removed, how do you plan the surgery to protect my nearby nerves, blood vessels, and healthy bone?

Questions For You

Tap a prompt to share your answer — we'll use it plus this page's context to start a tailored conversation.

References

References (27)
  1. 1

    Thin Cartilage Cap May Be Related to the Spontaneous Regression in Pediatric Patients with Osteochondroma.

    Adachi R, Nakamura T, Asanuma K, et al.

    Current oncology (Toronto, Ont.) 2022; (29(12)):9884-9890 doi:10.3390/curroncol29120777.

    PMID: 36547191
  2. 2

    Rib osteochondroma presenting as acute paraparesis.

    Kumar P, Badhe P, Dey AK

    Journal of cancer research and therapeutics 2022; (18(6)):1807-1808 doi:10.4103/jcrt.JCRT_400_20.

    PMID: 36412449
  3. 3

    Osteochondromas: An Updated Review of Epidemiology, Pathogenesis, Clinical Presentation, Radiological Features and Treatment Options.

    Tepelenis K, Papathanakos G, Kitsouli A, et al.

    In vivo (Athens, Greece) 2021; (35(2)):681-691 doi:10.21873/invivo.12308.

    PMID: 33622860
  4. 4

    Hereditary multiple exostoses of the ribs as an uncommon cause of pneumothorax: A case report.

    Dumazet A, Launois C, Dury S, et al.

    Medicine 2018; (97(35)):e11894 doi:10.1097/MD.0000000000011894.

    PMID: 30170381
  5. 5

    Malignant transformation of osteochondroma to chondrosarcoma: a challenging case.

    Sharifi Dalooei SMA, Aminzadeh B, Ataei N, et al.

    Skeletal radiology 2025; (54(8)):1767-1772 doi:10.1007/s00256-025-04898-2.

    PMID: 40011261
  6. 6

    Endoscopic endonasal extreme far-medial approach for a lower clivus osteochondroma in a patient with hereditary multiple exostoses: illustrative case.

    Morinaga Y, Akutsu H, Kino H, et al.

    Journal of neurosurgery. Case lessons 2021; (1(20)):CASE2153 doi:10.3171/CASE2153.

    PMID: 35855014
  7. 7

    Hereditary Multiple Exostoses-A Review of the Molecular Background, Diagnostics, and Potential Therapeutic Strategies.

    Bukowska-Olech E, Trzebiatowska W, Czech W, et al.

    Frontiers in genetics 2021; (12()):759129 doi:10.3389/fgene.2021.759129.

    PMID: 34956317
  8. 8

    Hereditary multiple exostoses: an educational review.

    Rueda-de-Eusebio A, Gomez-Pena S, Moreno-Casado MJ, et al.

    Insights into imaging 2025; (16(1)):46 doi:10.1186/s13244-025-01899-6.

    PMID: 39982564
  9. 9

    Whole-body MRI in assessing malignant transformation in multiple hereditary exostoses and enchondromatosis: audit results and literature review.

    Jurik AG, Jørgensen PH, Mortensen MM

    Skeletal radiology 2020; (49(1)):115-124 doi:10.1007/s00256-019-03268-z.

    PMID: 31273432
  10. 10

    What is the Proportion of Patients With Multiple Hereditary Exostoses Who Undergo Malignant Degeneration?

    Czajka CM, DiCaprio MR

    Clinical orthopaedics and related research 2015; (473(7)):2355-61 doi:10.1007/s11999-015-4134-z.

    PMID: 25582066
  11. 11

    Chondrosarcoma transformation in hereditary multiple exostoses: A systematic review and clinical and cost-effectiveness of a proposed screening model.

    Fei L, Ngoh C, Porter DE

    Journal of bone oncology 2018; (13()):114-122 doi:10.1016/j.jbo.2018.09.011.

    PMID: 30591865
  12. 12

    Late presentation of spinal cord compression in hereditary multiple exostosis: case reports and review of the literature.

    Gigi R, Kurian BT, Cole A, Fernandes JA

    Journal of children's orthopaedics 2019; (13(5)):463-470 doi:10.1302/1863-2548.13.180130.

    PMID: 31695813
  13. 13

    An Unusual Presentation of Costal Intraspinal Osteochondroma Causing Compressive Myelopathy in a Patient With Hereditary Multiple Exostoses: A Case Report and Literature Review.

    Jeevo J, N V A, Shekoba M

    Cureus 2024; (16(10)):e71036 doi:10.7759/cureus.71036.

    PMID: 39512974
  14. 14

    Radiographic Analysis of the Pediatric Hip Patients With Hereditary Multiple Exostoses (HME).

    Duque Orozco MDP, Abousamra O, Rogers KJ, Thacker MM

    Journal of pediatric orthopedics 2018; (38(6)):305-311 doi:10.1097/BPO.0000000000000815.

    PMID: 27328120
  15. 15

    Sarcomatous Transformation of Recurrent Scapular Osteochondroma in a Patient with the Hereditary Multiple Osteochondromas: A Case Report and Literature Review.

    Sajid S, Yousaf A, Nabi U, et al.

    Cureus 2019; (11(12)):e6308 doi:10.7759/cureus.6308.

    PMID: 31938600
  16. 16

    Update on Cancer Screening in Children with Syndromes of Bone Lesions, Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome, and Other Rare Syndromes.

    Michaeli O, Kim SY, Mitchell SG, et al.

    Clinical cancer research : an official journal of the American Association for Cancer Research 2025; (31(3)):457-465 doi:10.1158/1078-0432.CCR-24-2171.

    PMID: 39601780
  17. 17

    Management of nerve compression in multiple hereditary exostoses: a report of two cases and review of the literature.

    Payne R, Sieg E, Fox E, et al.

    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2016; (32(12)):2453-2458 doi:10.1007/s00381-016-3166-3.

    PMID: 27444292
  18. 18

    Spontaneous Regression of Multiple Osteochondromas in a Patient With Hereditary Multiple Exostoses: A Case Report.

    Ikeda K, Teruya S, Tsuge H, Onishi S

    Cureus 2025; (17(7)):e88111 doi:10.7759/cureus.88111.

    PMID: 40821248
  19. 19

    Osteochondroma Arising from Dorsal Pedicle Causing Compressive Myelopathy.

    Jain M, Unnava N, Sahu RN, et al.

    Journal of orthopaedic case reports 2026; (16(1)):128-132 doi:10.13107/jocr.2026.v16.i01.6624.

    PMID: 41541476
  20. 20

    Is Navigation-guided En Bloc Resection Advantageous Compared With Intralesional Curettage for Locally Aggressive Bone Tumors?

    Farfalli GL, Albergo JI, Piuzzi NS, et al.

    Clinical orthopaedics and related research 2018; (476(3)):511-517 doi:10.1007/s11999.0000000000000054.

    PMID: 29529633
  21. 21

    A solitary osteochondroma of the sixth cervical spine: A case report.

    Joshi G, Bhatta OP, Chand H, et al.

    International journal of surgery case reports 2023; (110()):108729 doi:10.1016/j.ijscr.2023.108729.

    PMID: 37657384
  22. 22

    Total resection of sacral giant cell tumor with en bloc resection, sacral nerve reconstruction, and custom 3D-printed implant: a case report with long-term follow-up.

    Hu D, Song F, Xiao S

    International journal of surgery case reports 2025; (130()):111293 doi:10.1016/j.ijscr.2025.111293.

    PMID: 40228346
  23. 23

    Modified ulnar lengthening for correction of the Masada type 2 forearm deformity in hereditary multiple exostosis.

    Cao S, Zeng JF, Xiao S, et al.

    Scientific reports 2023; (13(1)):10554 doi:10.1038/s41598-023-37532-z.

    PMID: 37386285
  24. 24

    Planned Realignment Osteotomies Ahead of Knee Arthroplasty for Pronounced Joint Malalignment: A Case Report in Hereditary Multiple Exostoses Disease.

    Schmid T, Schmid M, Schai PA

    Arthroplasty today 2024; (30()):101519 doi:10.1016/j.artd.2024.101519.

    PMID: 39559546
  25. 25

    Ulnar lengthening in the treatment of forearm deformity caused by hereditary multiple exostoses in children.

    Wang S, Liu HR, Zou KT, et al.

    World journal of orthopedics 2025; (16(7)):108319 doi:10.5312/wjo.v16.i7.108319.

    PMID: 40709297
  26. 26

    Hereditary Multiple Exostoses: a review of clinical appearance and metabolic pattern.

    Beltrami G, Ristori G, Scoccianti G, et al.

    Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases 2016; (13(2)):110-118 doi:10.11138/ccmbm/2016.13.2.110.

    PMID: 27920806
  27. 27

    Health-related quality of life and associated risk factors in patients with Multiple Osteochondromas: a cross-sectional study.

    Boarini M, Tremosini M, Di Cecco A, et al.

    Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 2024; (33(5)):1323-1334 doi:10.1007/s11136-024-03604-4.

    PMID: 38457053

This information about orthopedic oncology care is for educational purposes only and does not replace professional medical advice. Always consult your orthopedic oncologist regarding your specific monitoring schedule and any changes in your osteochondromas.

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