Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
Top Authors
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The University of Texas MD Anderson Cancer Center
Houston, United States
Centre Léon Bérard
Lyon, France
Fondazione IRCCS Istituto Nazionale dei Tumori
Milan, Italy
St. Jude Children's Research Hospital
Memphis, United States
Institut Gustave Roussy
Villejuif, France
Istituto Ortopedico Rizzoli
Bologna, Italy
Broad Institute
Cambridge, United States
Institut Curie
Paris, France
Oslo University Hospital
Oslo, Norway
National Institutes of Health
Bethesda, United States
References
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JAAPA : official journal of the American Academy of Physician Assistants 2018; (31(8)):15-19 doi:10.1097/01.JAA.0000541477.24116.8d.
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Descriptive epidemiology and outcomes of bone sarcomas in adolescent and young adult patients in Japan.
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BMC musculoskeletal disorders 2018; (19(1)):297 doi:10.1186/s12891-018-2217-1.
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Bone sarcomas: ESMO-PaedCan-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up.
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Surgical and Psychosocial Predictors of Mental Health in Parents of Children With Cardiac Admissions.
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Percutaneous Imaging-Guided versus Open Musculoskeletal Biopsy: Concepts and Controversies.
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Prediction of soft tissue coverage following distal femur bone sarcoma resection: A preliminary report.
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Factors Affecting Prognosis and Survival in Extremity Osteosarcoma.
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Correlation between Prognostic Factors and the Histopathological Response to Neoadjuvant Chemotherapy in Osteosarcoma: A Retrospective Study.
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Needle tract seeding following percutaneous biopsy of pediatric head and neck sarcoma: A case report.
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Clinical Statistical Analysis with Comparison between Pelvic and Non-pelvic Chondrosarcoma.
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Local Lung Mass Masquerading a Very Aggressive Extraskeletal Ewing Sarcoma Presenting as Bilateral Paraparesis in a Young Adult.
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Journal of children's orthopaedics 2021; (15(4)):312-321 doi:10.1302/1863-2548.15.210107.
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The Thioredoxin Reductase Inhibitor Auranofin Suppresses Pulmonary Metastasis of Osteosarcoma, But Not Local Progression.
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One oncogene, several vulnerabilities: EWS/FLI targeted therapies for Ewing sarcoma.
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Development and Verification of a Hypoxic Gene Signature for Predicting Prognosis, Immune Microenvironment, and Chemosensitivity for Osteosarcoma.
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Amputation Predisposes to Higher Cancer-Specific Mortality Than Limb Salvage Surgery in Pediatric Patients With Osteosarcoma of the Limbs: A Propensity Matching Analysis.
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Osteosarcoma: A Surveillance, Epidemiology, and End Results program-based analysis from 1975 to 2017.
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Cancer 2022; (128(11)):2107-2118 doi:10.1002/cncr.34163.
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Role of Individual, Family, and Community Resilience in Moderating Effects of Adverse Childhood Experiences on Mental Health Among Children.
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Single-Cell Profiling of Tumor Microenvironment Heterogeneity in Osteosarcoma Identifies a Highly Invasive Subcluster for Predicting Prognosis.
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Efficacy of Neoadjuvant Chemotherapy plus Limb-Sparing Surgery for Osteosarcoma and Its Impact on Long-Term Quality of Life.
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Systemic treatment for primary malignant sarcomas arising in craniofacial bones.
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Imaging of pediatric bone tumors: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper.
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Comparison of two chemotherapy regimens in patients with newly diagnosed Ewing sarcoma (EE2012): an open-label, randomised, phase 3 trial.
Brennan B, Kirton L, Marec-Bérard P, et al.
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Bone sarcoma follow-up; a nationwide analysis of oncological events after initial treatment.
Goedhart LM, Ho VKY, Ploegmakers JJW, et al.
Journal of bone oncology 2023; (38()):100466 doi:10.1016/j.jbo.2022.100466.
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Case report and literature review: Primary leiomyosarcoma of the bone in the trochanteric region of the femur.
Wu Z, Cheng L, Cao Q, et al.
Frontiers in surgery 2022; (9()):1045307 doi:10.3389/fsurg.2022.1045307.
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Molecular and Translational Research on Bone Tumors.
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International journal of molecular sciences 2023; (24(3)) doi:10.3390/ijms24031946.
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Prognostic analysis of telangiectatic osteosarcoma of the extremities.
Zhong W, Luo W, Lin Z, et al.
Frontiers in oncology 2022; (12()):1105054 doi:10.3389/fonc.2022.1105054.
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The impact of surgical resection margins on outcomes for adults with head and neck osteosarcomas: A Canadian sarcoma research and Clinical Collaboration (CanSaRCC) study.
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Oral oncology 2023; (145()):106495 doi:10.1016/j.oraloncology.2023.106495.
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Dedifferentiated Chondrosarcoma from Molecular Pathology to Current Treatment and Clinical Trials.
Zając W, Dróżdż J, Kisielewska W, et al.
Cancers 2023; (15(15)) doi:10.3390/cancers15153924.
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Recognizing and treating patients with Ewing sarcoma.
Windheuser A, Gardner N
JAAPA : official journal of the American Academy of Physician Assistants 2023; (36(9)):1-4 doi:10.1097/01.JAA.0000937324.58262.55.
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A meta-analysis of the efficacy and safety of first-line chemotherapeutic agents for osteosarcoma.
Li Z, Ma X, Wang Z, et al.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024; (33(5)):445-454 doi:10.17219/acem/170098.
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Disruption of the TP53 locus in osteosarcoma leads to TP53 promoter gene fusions and restoration of parts of the TP53 signalling pathway.
Saba KH, Difilippo V, Kovac M, et al.
The Journal of pathology 2024; (262(2)):147-160 doi:10.1002/path.6219.
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Does an excision of needle bone biopsy tract affect the prognosis in patients with primary bone tumor?
Gami A, Shah A, Shankaralingappa S, et al.
Journal of orthopaedics 2024; (48()):13-19 doi:10.1016/j.jor.2023.11.039.
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The significance of surveillance imaging in children with Ewing sarcoma and osteosarcoma.
Brekke SG, Lucke A, Hasle H, Baad-Hansen T
Pediatric hematology and oncology 2024; (41(4)):273-282 doi:10.1080/08880018.2024.2311407.
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Care Models and Barriers to Long-Term Follow-Up Care Among Childhood Cancer Survivors and Health Care Providers in Asia: A Literature Review.
Cai J, Cheung YT, Hudson MM
JCO global oncology 2024; (10()):e2300331 doi:10.1200/GO.23.00331.
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Bone Sarcoma Survival in the US Military Health System: Comparison With the SEER Program.
Anderson AB, Kim E, Park AB, et al.
The Journal of the American Academy of Orthopaedic Surgeons 2024; (32(13)):e651-e660 doi:10.5435/JAAOS-D-23-00897.
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Bone Radiation-Induced Sarcomas: Outcomes Based on Histology and Surgical Treatment: A Systematic Review of the Literature.
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JBJS reviews 2024; (12(8)) doi:10.2106/JBJS.RVW.24.00066.
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Doxorubicin-related cardiotoxicity: review of fundamental pathways of cardiovascular system injury.
Avagimyan A, Pogosova N, Kakturskiy L, et al.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2024; (73()):107683 doi:10.1016/j.carpath.2024.107683.
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Histopathological Response to Neoadjuvant Chemotherapy in Patients With Enneking Stage II Conventional Osteosarcoma of Extremities: A Retrospective-Single Institution Study in Vietnam.
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Cancer control : journal of the Moffitt Cancer Center 2024; (31()):10732748241274188 doi:10.1177/10732748241274188.
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Patient-specific guides for consistently achieving R0 bone margins after resection of primary malignant bone tumors of the pelvis.
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World journal of surgical oncology 2024; (22(1)):233 doi:10.1186/s12957-024-03478-3.
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UK guidelines for the management of bone sarcomas.
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British journal of cancer 2025; (132(1)):32-48 doi:10.1038/s41416-024-02868-4.
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Limb Salvage Surgery in Pediatric Patients with Osteosarcoma.
Niculescu ȘA, Grecu AF, Gheonea C, Grecu DC
Current health sciences journal 2024; (50(3)):360-367 doi:10.12865/CHSJ.50.03.03.
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Examining Interventions for Pediatric Adverse Childhood Experiences in an Integrated Primary Care Setting.
Rosado JI, Gabany S, Fortino M, Fernandez-Garcia A
Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners 2025; (39(2)):155-163 doi:10.1016/j.pedhc.2024.10.015.
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Determinants of tumor necrosis and its impact on outcome in patients with Localized osteosarcoma uniformly treated with a response adapted regimen without high dose Methotrexate- A retrospective institutional analysis.
Roy PG, Ganguly S, Sasi A, et al.
Journal of bone oncology 2024; (49()):100651 doi:10.1016/j.jbo.2024.100651.
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Evaluation of the Diagnostic Accuracy of Percutaneous Core Needle Biopsy in Bone and Soft Tissue Tumors.
Cengiz T, Yurtbay A, Muslu O, et al.
Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca 2024; (91(6)):376-384 doi:10.55095/ACHOT2024/042.
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Predictive Factors for Lung Metastasis in High-Grade Osteosarcoma: A 5 Years Experience from Tertiary Referral Hospital.
Prabowo Putro YA, Magetsari R, Oksikimbawan Tampubolon Y, et al.
Acta orthopaedica Belgica 2024; (90(4)):739-743 doi:10.52628/90.4.12808.
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Amputation Versus Limb-Salvage Surgery as Treatments for Pediatric Bone Sarcoma: A Comparative Study of Survival, Function, and Quality of Life.
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Cureus 2025; (17(2)):e78543 doi:10.7759/cureus.78543.
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Genomic Characterization of Chondrosarcoma Reveals Potential Therapeutic Targets.
Wagner MJ, Pimenta EM, Sweeney NW, et al.
JCO precision oncology 2025; (9()):e2400592 doi:10.1200/PO-24-00592.
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Bone Cancer, Version 2.2025, NCCN Clinical Practice Guidelines In Oncology.
Biermann JS, Hirbe A, Ahlawat S, et al.
Journal of the National Comprehensive Cancer Network : JNCCN 2025; (23(4)).
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Post-treatment late and long-term effects in bone sarcoma: A scoping review.
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Journal of bone oncology 2025; (52()):100671 doi:10.1016/j.jbo.2025.100671.
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Survivorship therapy needs after radiotherapy for head and neck cancer: surveying opportunities for growth (STRONG).
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Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2025; (33(5)):403 doi:10.1007/s00520-025-09429-2.
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Imaging features at the time of diagnosis of osteosarcoma and Ewing sarcoma in children.
Moreno-Reina C, Bueno-Gómez M, Guitiérrez-Carrasco JI, Caro-Domínguez P
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Epidemiology and Chemosensitivity of Primary Malignant Bone Tumors at a Teaching Hospital in South Africa: A 5-Year Retrospective Analysis.
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Medical science monitor : international medical journal of experimental and clinical research 2025; (31()):e948274 doi:10.12659/MSM.948274.
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Survivorship care and mortality in a contemporary and diverse cohort of childhood cancer survivors.
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Journal of the National Cancer Institute 2025; doi:10.1093/jnci/djaf276.
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New cell lines expanding the diversity of Ewing sarcoma models.
Kerkhoff M, Schaefer C, Dirks WG, et al.
International journal of cancer 2026; (158(3)):642-655 doi:10.1002/ijc.70172.
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EWS::FLI1 expression in human embryonic mesenchymal stem cells leads to transcriptional reprograming, defective DNA damage repair and Ewing sarcoma.
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Nature communications 2025; (16(1)):9427 doi:10.1038/s41467-025-64475-y.
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Magnetic resonance imaging features of primary appendicular bone sarcomas in 20 dogs.
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The Journal of small animal practice 2026; (67(4)):343-352 doi:10.1111/jsap.70070.
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The hegemonic EWSR1::ETS oncoprotein overrules core regulatory circuitry principles in Ewing sarcoma.
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DISTAL (Distal tibia tumors treated with amputation versus limb Salvage): A systematic review and meta-analysis of oncologic, functional, and complication outcomes in malignant bone tumors.
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Self-disclosure dynamics in psychological crisis among Chinese pediatric patients with severe nocturnal enuresis: A qualitative inquiry.
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Journal of family medicine and primary care 2025; (14(12)):5066-5071 doi:10.4103/jfmpc.jfmpc_376_25.
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Long-term Outcomes of 3-dimensional-printed Cutting Guides for Long Bone Sarcoma Resection and Intercalary Allograft Reconstruction: An Updated Case Series.
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PATIENTS WITH SOFT TISSUE SARCOMA AFTER TREATMENT BY NON ORTHOPEDIC ONCOLOGIC SURGEONS: EPIDEMIOLOGICAL PROFILE, STAGING, AND THERAPEUTIC CHALLENGES.
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