Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
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The University of Texas MD Anderson Cancer Center
Houston, United States
Novartis (Switzerland)
Basel, Switzerland
Inserm
Paris, France
Heidelberg University
Heidelberg, Germany
South Australia Pathology
Adelaide, Australia
University Medical Centre Mannheim
Mannheim, Germany
Memorial Sloan Kettering Cancer Center
New York, United States
Praxis für Hämatologie und Onkologie
Saarbrücken, Germany
Novartis (United States)
New York, United States
Hammersmith Hospital
London, United Kingdom
References
References (115)
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Further augmentation of molecular responses with dasatinib therapy in chronic myeloid leukemia patients who gained major molecular response under imatinib.
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The impact of early molecular response in children and adolescents with chronic myeloid leukemia treated with imatinib: a single-center study from China.
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A double Philadelphia chromosome-positive chronic myeloid leukemia patient, co-expressing P210BCR-ABL1 and P195BCR-ABL1 isoforms.
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Analytical Validation of a Highly Sensitive, Multiplexed Chronic Myeloid Leukemia Monitoring System Targeting BCR-ABL1 RNA.
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Beyond the comfort zone of deep molecular response: discontinuation in major molecular response chronic myeloid leukemia.
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Yet do much less...so much less!
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Blood 2019; (134(1)):6-7 doi:10.1182/blood.2019001014.
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The role of ponatinib in chronic myeloid leukemia in the era of treatment free remission.
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Towards a Personalized Treatment of Patients with Chronic Myeloid Leukemia.
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Are we ready to use precision medicine in chronic myeloid leukemia practice?
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Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure.
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Pharmacology of tyrosine kinase inhibitors in chronic myeloid leukemia; a clinician's perspective.
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Mechanisms of Cardiovascular Toxicity of BCR-ABL1 Tyrosine Kinase Inhibitors in Chronic Myelogenous Leukemia.
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Validation of the EUTOS Long-Term Survival Score in Chinese Chronic Myeloid Leukemia Patients Treated with Imatinib: A Multicenter Real-World Study.
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European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia.
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Halving Time of BCR-ABL1 in Chronic Myeloid Leukemia: Is It Better Than Day-90 Value-A Multicenter Study From South India.
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Clinical lymphoma, myeloma & leukemia 2020; (20(5)):e205-e211 doi:10.1016/j.clml.2019.09.606.
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Dasatinib vs. imatinib in patients with chronic myeloid leukemia in chronic phase (CML-CP) who have not achieved an optimal response to 3 months of imatinib therapy: the DASCERN randomized study.
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Phase 2 study of bosutinib in Japanese patients with newly diagnosed chronic phase chronic myeloid leukemia.
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Chronic Myeloid Leukemia: Atypical Presentation and Diagnostic Pitfall in the Workup of Isolated Thrombocytosis.
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Cureus 2020; (12(6)):e8498 doi:10.7759/cureus.8498.
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Current Strategies and Future Directions to Achieve Deep Molecular Response and Treatment-Free Remission in Chronic Myeloid Leukemia.
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Frontiers in oncology 2020; (10()):883 doi:10.3389/fonc.2020.00883.
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The EUTOS long-term survival (ELTS) score is superior to the Sokal score for predicting survival in chronic myeloid leukemia.
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Leukemia 2020; (34(8)):2138-2149 doi:10.1038/s41375-020-0931-9.
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Finding new lanes: Chimeric antigen receptor (CAR) T-cells for myeloid leukemia.
Pratap S, Zhao ZJ
Cancer reports (Hoboken, N.J.) 2020; (3(2)):e1222 doi:10.1002/cnr2.1222.
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Moving on from 2013 to 2020 European LeukemiaNet recommendations for treating chronic myeloid leukemia: what has changed over the 7 years?
Yilmaz U, Eskazan AE
Expert review of hematology 2020; (13(10)):1035-1038 doi:10.1080/17474086.2020.1813564.
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Chronic Myeloid Leukemia, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.
Deininger MW, Shah NP, Altman JK, et al.
Journal of the National Comprehensive Cancer Network : JNCCN 2020; (18(10)):1385-1415.
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The EUTOS long-term survival score predicts disease-specific mortality and molecular responses among patients with chronic myeloid leukemia in a practice-based cohort.
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Cancer medicine 2020; (9(23)):8931-8939 doi:10.1002/cam4.3516.
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[Analysis of Clinical Characteristics in De novo Chronic Myelogenous Leukemia Patients with Extramedullary T-Lymphoblastic Blast Crisis].
Guan Y, Liu Q, Huang DP, He HS
Zhongguo shi yan xue ye xue za zhi 2020; (28(5)):1528-1533 doi:10.19746/j.cnki.issn.1009-2137.2020.05.017.
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A Retrospective Analysis about Frequency of Monitoring in Italian Chronic Myeloid Leukemia Patients after Discontinuation.
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Journal of clinical medicine 2020; (9(11)) doi:10.3390/jcm9113692.
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Chronic Myeloid Leukemia: A Model Disease of the Past, Present and Future.
Minciacchi VR, Kumar R, Krause DS
Cells 2021; (10(1)) doi:10.3390/cells10010117.
PMID: 33435150 - 58
Extramedullary Blast Crisis of Chronic Myelogenous Leukemia With a Skin Lesion: A Case Report and Literature Review.
Qi J, Zhang F, Liu Y, et al.
The American Journal of dermatopathology 2021; (43(6)):450-453 doi:10.1097/DAD.0000000000001897.
PMID: 33481378 - 59
Assessment of individual molecular response in chronic myeloid leukemia patients with atypical BCR-ABL1 fusion transcripts: recommendations by the EUTOS cooperative network.
Schäfer V, White HE, Gerrard G, et al.
Journal of cancer research and clinical oncology 2021; (147(10)):3081-3089 doi:10.1007/s00432-021-03569-8.
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Measuring prognosis in chronic myeloid leukemia: what's new?
Breccia M, Efficace F, Scalzulli E, et al.
Expert review of hematology 2021; (14(6)):577-585 doi:10.1080/17474086.2021.1938534.
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BCR-ABL1 p210 screening for chronic myeloid leukemia in patients with peripheral blood cytoses.
Fenu E, O'Neill SS, Insuasti-Beltran G
International journal of laboratory hematology 2021; (43(6)):1458-1464 doi:10.1111/ijlh.13635.
PMID: 34185393 - 62
Early prediction of stable MR4.5 by depth of molecular response at 6 months in patients with chronic myeloid leukemia treated with frontline imatinib.
Nee A, Lipton JH, Kim DDH
Leukemia & lymphoma 2022; (63(1)):162-169 doi:10.1080/10428194.2021.1961234.
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Genomic Copy Number Variants in CML Patients With the Philadelphia Chromosome (Ph+): An Update.
Zhang H, Liu M, Wang X, et al.
Frontiers in genetics 2021; (12()):697009 doi:10.3389/fgene.2021.697009.
PMID: 34447409 - 64
Prognostic Factors for Overall Survival In Chronic Myeloid Leukemia Patients: A Multicentric Cohort Study by the Italian CML GIMEMA Network.
Specchia G, Pregno P, Breccia M, et al.
Frontiers in oncology 2021; (11()):739171 doi:10.3389/fonc.2021.739171.
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Making Treatment-Free Remission (TFR) Easier in Chronic Myeloid Leukemia: Fact-Checking and Practical Management Tools.
Castagnetti F, Binotto G, Capodanno I, et al.
Targeted oncology 2021; (16(6)):823-838 doi:10.1007/s11523-021-00831-4.
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Blast and accelerated phase CML: room for improvement.
How J, Venkataraman V, Hobbs GS
Hematology. American Society of Hematology. Education Program 2021; (2021(1)):122-128 doi:10.1182/hematology.2021000240.
PMID: 34889372 - 67
TKI discontinuation in CML: how do we make more patients eligible? How do we increase the chances of a successful treatment-free remission?
Hochhaus A, Ernst T
Hematology. American Society of Hematology. Education Program 2021; (2021(1)):106-112 doi:10.1182/hematology.2021000238.
PMID: 34889388 - 68
Dasatinib-Induced Colitis with Rectal Sparing in a Patient with Chronic Myeloid Leukemia (Chronic Phase) on Dasatinib as an Upfront Therapy: Case Report.
Maat Z, Mushtaq K, Yassin MA
Case reports in oncology 2021; (14(3)):1441-1446 doi:10.1159/000516794.
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Targeting BCR-Abl in the treatment of Philadelphia-chromosome positive chronic myelogenous leukemia.
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Pharmacological research 2022; (178()):106156 doi:10.1016/j.phrs.2022.106156.
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How I Manage Patients with Chronic Myeloid Leukemia (CML): Perspectives from Clinical Practice.
Guru Murthy GS
Blood and lymphatic cancer : targets and therapy 2022; (12()):1-6 doi:10.2147/BLCTT.S219160.
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Ponatinib for the treatment of adult patients with resistant or intolerant Chronic-Phase Chronic Myeloid Leukemia.
Haddad FG, Issa GC, Jabbour E, Yilmaz M
Expert opinion on pharmacotherapy 2022; (23(7)):751-758 doi:10.1080/14656566.2022.2064742.
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Patient- and physician-reported pain after tyrosine kinase inhibitor discontinuation among patients with chronic myeloid leukemia.
Flynn KE, Atallah E, Lin L, et al.
Haematologica 2022; (107(11)):2641-2649 doi:10.3324/haematol.2021.280377.
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Kinetics of early and late molecular recurrences after first-line imatinib cessation in chronic myeloid leukemia: updated results from the STIM2 trial.
Dulucq S, Nicolini FE, Rea D, et al.
Haematologica 2022; (107(12)):2859-2869 doi:10.3324/haematol.2022.280811.
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Predictive Factors for Molecular Response in Chronic Myeloid Leukemia: Reduction Ratio and Halving Time of BCR::ABL1 IS Transcript Levels
Ceran F, Akıncı S, Uçar MA, et al.
Turkish journal of haematology : official journal of Turkish Society of Haematology 2022; (39(3)):196-203 doi:10.4274/tjh.galenos.2022.2022-0024.
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Highly sensitive droplet digital polymerase chain reaction for BCR::ABL1 messenger RNA identifies patients with chronic myeloid leukaemia with a low probability of achieving treatment-free remission.
Lu L, Kok CH, Dang P, et al.
British journal of haematology 2022; (198(3)):600-603 doi:10.1111/bjh.18277.
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The effect of comorbidities on the choice of tyrosine kinase inhibitors in patients with chronic myeloid leukemia.
Saydam G, Ali R, Demir AM, et al.
International journal of hematologic oncology 2022; (11(1)):IJH38 doi:10.2217/ijh-2021-0010.
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Turkey real-life data: demographic features, treatment results and effects of comorbidities in chronic myeloid leukemia.
Saydam G, Unal A, Haznedaroglu IC, et al.
International journal of hematologic oncology 2022; (11(3)):IJH40 doi:10.2217/ijh-2021-0008.
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Deep molecular response in patients with chronic phase chronic myeloid leukemia treated with the plasminogen activator inhibitor-1 inhibitor TM5614 combined with a tyrosine kinase inhibitor.
Takahashi N, Kameoka Y, Onizuka M, et al.
Cancer medicine 2023; (12(4)):4250-4258 doi:10.1002/cam4.5292.
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[Withdrawal syndrome after tyrosine kinase inhibitors discontinuation in patients with chronic myeloid leukemia].
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Terapevticheskii arkhiv 2022; (94(7)):836-843 doi:10.26442/00403660.2022.07.201747.
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Pathogenesis and management of accelerated and blast phases of chronic myeloid leukemia.
Senapati J, Jabbour E, Kantarjian H, Short NJ
Leukemia 2023; (37(1)):5-17 doi:10.1038/s41375-022-01736-5.
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[Acute lymphoblastic leukemia with "masked" Philadelphia chromosome].
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[Rinsho ketsueki] The Japanese journal of clinical hematology 2022; (63(11)):1525-1529 doi:10.11406/rinketsu.63.1525.
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Long-term outcomes of third-line therapy with tyrosine kinase inhibitors in chronic phase chronic myeloid leukemia: A real-life experience.
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Frontiers in oncology 2023; (13()):1138683 doi:10.3389/fonc.2023.1138683.
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An interesting case of chronic myeloid leukemia (CML) with T315I mutation raising suspicion of de novo AML, a diagnostic conundrum.
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Clinical case reports 2023; (11(5)):e5908 doi:10.1002/ccr3.5908.
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Occurrence of L1M Elements in Chromosomal Rearrangements Associated to Chronic Myeloid Leukemia (CML): Insights from Patient-Specific Breakpoints Characterization.
L'Abbate A, Moretti V, Pungolino E, et al.
Genes 2023; (14(7)) doi:10.3390/genes14071351.
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Identification of rare atypical BCR-ABL1 transcript: A case report.
Saha J, Gopinath V, Nair CK, Roshan D
Indian journal of pathology & microbiology 2023; (66(3)):624-626 doi:10.4103/ijpm.ijpm_715_21.
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An Update on the Management of Advanced Phase Chronic Myeloid Leukemia.
Short NJ, Senapati J, Jabbour E
Current hematologic malignancy reports 2023; (18(6)):234-242 doi:10.1007/s11899-023-00709-4.
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Harmonizing the craft of crafting clinically endorsed small-molecule BCR-ABL tyrosine kinase inhibitors for the treatment of hematological malignancies.
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European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024; (193()):106678 doi:10.1016/j.ejps.2023.106678.
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Exploration of treatment-free remission in CML, based on molecular monitoring.
Zhang Z, Zhou X, Zhou X, et al.
Cancer medicine 2024; (13(1)):e6849 doi:10.1002/cam4.6849.
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Effect of Tyrosine Kinase Inhibitor Therapy on Estimated Glomerular Filtration Rate in Patients with Chronic Myeloid Leukemia.
Sönmez Ö, Özgür Yurttaş N, İhtiyaroğlu İ, et al.
Clinical lymphoma, myeloma & leukemia 2024; (24(4)):232-239 doi:10.1016/j.clml.2023.12.004.
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Chronic Myeloid Leukemia, Version 2.2024, NCCN Clinical Practice Guidelines in Oncology.
Shah NP, Bhatia R, Altman JK, et al.
Journal of the National Comprehensive Cancer Network : JNCCN 2024; (22(1)):43-69 doi:10.6004/jnccn.2024.0007.
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