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PubMed This is a summary of 115 peer-reviewed journal articles Updated

Research & Literature

Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.

Explore the Literature Visualize citation networks across 115 referenced papers

Top Authors

Andreas Hochhaus
University Medical Centre Mannheim
Jörge E. Cortes
The University of Texas MD Anderson Cancer Center
Hagop M. Kantarjian
The University of Texas MD Anderson Cancer Center
Robert Roskoski
Blue Ridge Research and Consulting (United States)
Timothy P. Hughes
South Australia Pathology
Elias Jabbour
The University of Texas MD Anderson Cancer Center
Delphine Réa
Assistance Publique – Hôpitaux de Paris
Michael W. Deininger
Hammersmith Hospital
Susanne Saußele
University of Mannheim
Massimo Breccia
Policlinico Umberto I

Top Institutions

Ranked by publications Top 10 institutions
01

The University of Texas MD Anderson Cancer Center

Houston, United States

294 papers
06

University Medical Centre Mannheim

Mannheim, Germany

107 papers

References

References (115)
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    E14a2 BCR-ABL1 transcript is associated with a higher rate of treatment-free remission in individuals with chronic myeloid leukemia after stopping tyrosine kinase inhibitor therapy.

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    Deregulated expression of Cdc6 as BCR/ABL-dependent survival factor in chronic myeloid leukemia cells.

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    Tyrosine Kinase Inhibitor Treatment for Newly Diagnosed Chronic Myeloid Leukemia.

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    Immunohistochemistry in Acute Myeloid Leukemia.

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    Second tyrosine kinase inhibitor discontinuation attempt in patients with chronic myeloid leukemia.

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    Cancer 2017; (123(22)):4403-4410 doi:10.1002/cncr.30885.

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    Rapid reduction in BCR-ABL1 transcript predicts deep molecular response in dasatinib-treated chronic-phase chronic myeloid leukaemia patients.

    Murai K, Yamaguchi K, Ito S, et al.

    European journal of haematology 2018; (100(1)):27-35 doi:10.1111/ejh.12969.

    PMID: 28895203
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    How to detect the rare BCR-ABL (e14a3) transcript: A case report and literature review.

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    Oncology letters 2017; (14(5)):5619-5623 doi:10.3892/ol.2017.6847.

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    Further augmentation of molecular responses with dasatinib therapy in chronic myeloid leukemia patients who gained major molecular response under imatinib.

    Eskazan AE

    International journal of clinical oncology 2018; (23(2)):400-401 doi:10.1007/s10147-017-1214-y.

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    The impact of early molecular response in children and adolescents with chronic myeloid leukemia treated with imatinib: a single-center study from China.

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    Leukemia & lymphoma 2018; (59(9)):2152-2158 doi:10.1080/10428194.2017.1422860.

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    Outcomes of switching to dasatinib after imatinib-related low-grade adverse events in patients with chronic myeloid leukemia in chronic phase: the DASPERSE study.

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    Annals of hematology 2018; (97(8)):1357-1367 doi:10.1007/s00277-018-3295-8.

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    The issue of financial toxicity in the management of chronic myeloid leukemia with blast crisis.

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    Journal of medical economics 2018; (21(7)):709-711 doi:10.1080/13696998.2018.1467919.

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    NKG2D-based chimeric antigen receptor therapy induced remission in a relapsed/refractory acute myeloid leukemia patient.

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    Haematologica 2018; (103(9)):e424-e426 doi:10.3324/haematol.2017.186742.

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    Discontinuation of tyrosine kinase inhibitors in chronic myeloid leukemia: Recommendations for clinical practice from the French Chronic Myeloid Leukemia Study Group.

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    Cancer 2018; (124(14)):2956-2963 doi:10.1002/cncr.31411.

    PMID: 29723417
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    Discontinuation of tyrosine kinase inhibitor therapy in chronic myeloid leukaemia (EURO-SKI): a prespecified interim analysis of a prospective, multicentre, non-randomised, trial.

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    The Lancet. Oncology 2018; (19(6)):747-757 doi:10.1016/S1470-2045(18)30192-X.

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    Early BCR-ABL1 decline in imatinib-treated patients with chronic myeloid leukemia: results from a multicenter study of the Chinese CML alliance.

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    Blood cancer journal 2018; (8(7)):61 doi:10.1038/s41408-018-0093-4.

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    Past, present, and future of Bcr-Abl inhibitors: from chemical development to clinical efficacy.

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    A double Philadelphia chromosome-positive chronic myeloid leukemia patient, co-expressing P210BCR-ABL1 and P195BCR-ABL1 isoforms.

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    Development, Function, and Clinical Significance of Plasmacytoid Dendritic Cells in Chronic Myeloid Leukemia.

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    Cancer research 2018; (78(21)):6223-6234 doi:10.1158/0008-5472.CAN-18-1477.

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    Chronic Myeloid Leukemia, Version 1.2019, NCCN Clinical Practice Guidelines in Oncology.

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    Journal of the National Comprehensive Cancer Network : JNCCN 2018; (16(9)):1108-1135 doi:10.6004/jnccn.2018.0071.

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    Bone marrow core biopsy in 508 consecutive patients with chronic myeloid leukemia: Assessment of potential value.

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    Chronic myeloid leukemia with complex karyotypes: Prognosis and therapeutic approaches.

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    Differentiating factors in treatment-free remission trials: impact of study design on results and clinical applications.

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    Allogeneic stem cell transplantation for chronic myeloid leukemia in the TKI era: population-based data from the Swedish CML registry.

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    Analytical Validation of a Highly Sensitive, Multiplexed Chronic Myeloid Leukemia Monitoring System Targeting BCR-ABL1 RNA.

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    Beyond the comfort zone of deep molecular response: discontinuation in major molecular response chronic myeloid leukemia.

    Dragani M, Rege-Cambrin G, Ferrero D, et al.

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    Yet do much less...so much less!

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    The role of ponatinib in chronic myeloid leukemia in the era of treatment free remission.

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    Leukemia & lymphoma 2019; (60(13)):3099-3101 doi:10.1080/10428194.2019.1665667.

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    Towards a Personalized Treatment of Patients with Chronic Myeloid Leukemia.

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    Are we ready to use precision medicine in chronic myeloid leukemia practice?

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    Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure.

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    Pharmacology of tyrosine kinase inhibitors in chronic myeloid leukemia; a clinician's perspective.

    Pushpam D, Bakhshi S

    Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 2020; (28(1)):371-385 doi:10.1007/s40199-019-00321-z.

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    Mechanisms of Cardiovascular Toxicity of BCR-ABL1 Tyrosine Kinase Inhibitors in Chronic Myelogenous Leukemia.

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    Current hematologic malignancy reports 2020; (15(1)):20-30 doi:10.1007/s11899-020-00560-x.

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    Validation of the EUTOS Long-Term Survival Score in Chinese Chronic Myeloid Leukemia Patients Treated with Imatinib: A Multicenter Real-World Study.

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    European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia.

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    Halving Time of BCR-ABL1 in Chronic Myeloid Leukemia: Is It Better Than Day-90 Value-A Multicenter Study From South India.

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    Dasatinib vs. imatinib in patients with chronic myeloid leukemia in chronic phase (CML-CP) who have not achieved an optimal response to 3 months of imatinib therapy: the DASCERN randomized study.

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    Leukemia 2020; (34(8)):2064-2073 doi:10.1038/s41375-020-0805-1.

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    Phase 2 study of bosutinib in Japanese patients with newly diagnosed chronic phase chronic myeloid leukemia.

    Hino M, Matsumura I, Fujisawa S, et al.

    International journal of hematology 2020; (112(1)):24-32 doi:10.1007/s12185-020-02878-x.

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    Chronic Myeloid Leukemia: Atypical Presentation and Diagnostic Pitfall in the Workup of Isolated Thrombocytosis.

    Findakly D, Arslan W

    Cureus 2020; (12(6)):e8498 doi:10.7759/cureus.8498.

    PMID: 32528789
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    Current Strategies and Future Directions to Achieve Deep Molecular Response and Treatment-Free Remission in Chronic Myeloid Leukemia.

    Annunziata M, Bonifacio M, Breccia M, et al.

    Frontiers in oncology 2020; (10()):883 doi:10.3389/fonc.2020.00883.

    PMID: 32582549
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    The EUTOS long-term survival (ELTS) score is superior to the Sokal score for predicting survival in chronic myeloid leukemia.

    Pfirrmann M, Clark RE, Prejzner W, et al.

    Leukemia 2020; (34(8)):2138-2149 doi:10.1038/s41375-020-0931-9.

    PMID: 32601376
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    Finding new lanes: Chimeric antigen receptor (CAR) T-cells for myeloid leukemia.

    Pratap S, Zhao ZJ

    Cancer reports (Hoboken, N.J.) 2020; (3(2)):e1222 doi:10.1002/cnr2.1222.

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    Moving on from 2013 to 2020 European LeukemiaNet recommendations for treating chronic myeloid leukemia: what has changed over the 7 years?

    Yilmaz U, Eskazan AE

    Expert review of hematology 2020; (13(10)):1035-1038 doi:10.1080/17474086.2020.1813564.

    PMID: 32814447
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    Chronic Myeloid Leukemia, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.

    Deininger MW, Shah NP, Altman JK, et al.

    Journal of the National Comprehensive Cancer Network : JNCCN 2020; (18(10)):1385-1415.

    PMID: 33022644
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    The EUTOS long-term survival score predicts disease-specific mortality and molecular responses among patients with chronic myeloid leukemia in a practice-based cohort.

    Sato E, Iriyama N, Tokuhira M, et al.

    Cancer medicine 2020; (9(23)):8931-8939 doi:10.1002/cam4.3516.

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    [Analysis of Clinical Characteristics in De novo Chronic Myelogenous Leukemia Patients with Extramedullary T-Lymphoblastic Blast Crisis].

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    Zhongguo shi yan xue ye xue za zhi 2020; (28(5)):1528-1533 doi:10.19746/j.cnki.issn.1009-2137.2020.05.017.

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    A Retrospective Analysis about Frequency of Monitoring in Italian Chronic Myeloid Leukemia Patients after Discontinuation.

    Dragani M, Rege Cambrin G, Berchialla P, et al.

    Journal of clinical medicine 2020; (9(11)) doi:10.3390/jcm9113692.

    PMID: 33213044
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    Chronic Myeloid Leukemia: A Model Disease of the Past, Present and Future.

    Minciacchi VR, Kumar R, Krause DS

    Cells 2021; (10(1)) doi:10.3390/cells10010117.

    PMID: 33435150
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    Extramedullary Blast Crisis of Chronic Myelogenous Leukemia With a Skin Lesion: A Case Report and Literature Review.

    Qi J, Zhang F, Liu Y, et al.

    The American Journal of dermatopathology 2021; (43(6)):450-453 doi:10.1097/DAD.0000000000001897.

    PMID: 33481378
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    Assessment of individual molecular response in chronic myeloid leukemia patients with atypical BCR-ABL1 fusion transcripts: recommendations by the EUTOS cooperative network.

    Schäfer V, White HE, Gerrard G, et al.

    Journal of cancer research and clinical oncology 2021; (147(10)):3081-3089 doi:10.1007/s00432-021-03569-8.

    PMID: 33677711
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    Measuring prognosis in chronic myeloid leukemia: what's new?

    Breccia M, Efficace F, Scalzulli E, et al.

    Expert review of hematology 2021; (14(6)):577-585 doi:10.1080/17474086.2021.1938534.

    PMID: 34075852
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    BCR-ABL1 p210 screening for chronic myeloid leukemia in patients with peripheral blood cytoses.

    Fenu E, O'Neill SS, Insuasti-Beltran G

    International journal of laboratory hematology 2021; (43(6)):1458-1464 doi:10.1111/ijlh.13635.

    PMID: 34185393
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    Early prediction of stable MR4.5 by depth of molecular response at 6 months in patients with chronic myeloid leukemia treated with frontline imatinib.

    Nee A, Lipton JH, Kim DDH

    Leukemia & lymphoma 2022; (63(1)):162-169 doi:10.1080/10428194.2021.1961234.

    PMID: 34379028
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    Genomic Copy Number Variants in CML Patients With the Philadelphia Chromosome (Ph+): An Update.

    Zhang H, Liu M, Wang X, et al.

    Frontiers in genetics 2021; (12()):697009 doi:10.3389/fgene.2021.697009.

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    Prognostic Factors for Overall Survival In Chronic Myeloid Leukemia Patients: A Multicentric Cohort Study by the Italian CML GIMEMA Network.

    Specchia G, Pregno P, Breccia M, et al.

    Frontiers in oncology 2021; (11()):739171 doi:10.3389/fonc.2021.739171.

    PMID: 34513714
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    Making Treatment-Free Remission (TFR) Easier in Chronic Myeloid Leukemia: Fact-Checking and Practical Management Tools.

    Castagnetti F, Binotto G, Capodanno I, et al.

    Targeted oncology 2021; (16(6)):823-838 doi:10.1007/s11523-021-00831-4.

    PMID: 34661826
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    Blast and accelerated phase CML: room for improvement.

    How J, Venkataraman V, Hobbs GS

    Hematology. American Society of Hematology. Education Program 2021; (2021(1)):122-128 doi:10.1182/hematology.2021000240.

    PMID: 34889372
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    TKI discontinuation in CML: how do we make more patients eligible? How do we increase the chances of a successful treatment-free remission?

    Hochhaus A, Ernst T

    Hematology. American Society of Hematology. Education Program 2021; (2021(1)):106-112 doi:10.1182/hematology.2021000238.

    PMID: 34889388
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    Dasatinib-Induced Colitis with Rectal Sparing in a Patient with Chronic Myeloid Leukemia (Chronic Phase) on Dasatinib as an Upfront Therapy: Case Report.

    Maat Z, Mushtaq K, Yassin MA

    Case reports in oncology 2021; (14(3)):1441-1446 doi:10.1159/000516794.

    PMID: 34899234
  69. 69

    Targeting BCR-Abl in the treatment of Philadelphia-chromosome positive chronic myelogenous leukemia.

    Roskoski R

    Pharmacological research 2022; (178()):106156 doi:10.1016/j.phrs.2022.106156.

    PMID: 35257901
  70. 70

    How I Manage Patients with Chronic Myeloid Leukemia (CML): Perspectives from Clinical Practice.

    Guru Murthy GS

    Blood and lymphatic cancer : targets and therapy 2022; (12()):1-6 doi:10.2147/BLCTT.S219160.

    PMID: 35340664
  71. 71

    Ponatinib for the treatment of adult patients with resistant or intolerant Chronic-Phase Chronic Myeloid Leukemia.

    Haddad FG, Issa GC, Jabbour E, Yilmaz M

    Expert opinion on pharmacotherapy 2022; (23(7)):751-758 doi:10.1080/14656566.2022.2064742.

    PMID: 35412404
  72. 72

    Patient- and physician-reported pain after tyrosine kinase inhibitor discontinuation among patients with chronic myeloid leukemia.

    Flynn KE, Atallah E, Lin L, et al.

    Haematologica 2022; (107(11)):2641-2649 doi:10.3324/haematol.2021.280377.

    PMID: 35511672
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    Kinetics of early and late molecular recurrences after first-line imatinib cessation in chronic myeloid leukemia: updated results from the STIM2 trial.

    Dulucq S, Nicolini FE, Rea D, et al.

    Haematologica 2022; (107(12)):2859-2869 doi:10.3324/haematol.2022.280811.

    PMID: 35615931
  74. 74

    Predictive Factors for Molecular Response in Chronic Myeloid Leukemia: Reduction Ratio and Halving Time of BCR::ABL1 IS Transcript Levels

    Ceran F, Akıncı S, Uçar MA, et al.

    Turkish journal of haematology : official journal of Turkish Society of Haematology 2022; (39(3)):196-203 doi:10.4274/tjh.galenos.2022.2022-0024.

    PMID: 35620443
  75. 75

    Highly sensitive droplet digital polymerase chain reaction for BCR::ABL1 messenger RNA identifies patients with chronic myeloid leukaemia with a low probability of achieving treatment-free remission.

    Lu L, Kok CH, Dang P, et al.

    British journal of haematology 2022; (198(3)):600-603 doi:10.1111/bjh.18277.

    PMID: 35620965
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    The effect of comorbidities on the choice of tyrosine kinase inhibitors in patients with chronic myeloid leukemia.

    Saydam G, Ali R, Demir AM, et al.

    International journal of hematologic oncology 2022; (11(1)):IJH38 doi:10.2217/ijh-2021-0010.

    PMID: 35664044
  77. 77

    Turkey real-life data: demographic features, treatment results and effects of comorbidities in chronic myeloid leukemia.

    Saydam G, Unal A, Haznedaroglu IC, et al.

    International journal of hematologic oncology 2022; (11(3)):IJH40 doi:10.2217/ijh-2021-0008.

    PMID: 36101779
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    Deep molecular response in patients with chronic phase chronic myeloid leukemia treated with the plasminogen activator inhibitor-1 inhibitor TM5614 combined with a tyrosine kinase inhibitor.

    Takahashi N, Kameoka Y, Onizuka M, et al.

    Cancer medicine 2023; (12(4)):4250-4258 doi:10.1002/cam4.5292.

    PMID: 36151699
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    [Withdrawal syndrome after tyrosine kinase inhibitors discontinuation in patients with chronic myeloid leukemia].

    Chelysheva EY, Petrova AN, Shukhov OA, et al.

    Terapevticheskii arkhiv 2022; (94(7)):836-843 doi:10.26442/00403660.2022.07.201747.

    PMID: 36286940
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    Pathogenesis and management of accelerated and blast phases of chronic myeloid leukemia.

    Senapati J, Jabbour E, Kantarjian H, Short NJ

    Leukemia 2023; (37(1)):5-17 doi:10.1038/s41375-022-01736-5.

    PMID: 36309558
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    [Acute lymphoblastic leukemia with "masked" Philadelphia chromosome].

    Naganuma K, Tabayashi T, Kawada T, et al.

    [Rinsho ketsueki] The Japanese journal of clinical hematology 2022; (63(11)):1525-1529 doi:10.11406/rinketsu.63.1525.

    PMID: 36476792
  82. 82

    Long-term outcomes of third-line therapy with tyrosine kinase inhibitors in chronic phase chronic myeloid leukemia: A real-life experience.

    Chitanava T, Matvienko I, Shuvaev V, et al.

    Frontiers in oncology 2023; (13()):1138683 doi:10.3389/fonc.2023.1138683.

    PMID: 37007128
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