Skip to content
PubMed This is a summary of 22 peer-reviewed journal articles Updated
Gastroenterology · Hemorrhoids

Symptoms, Warning Signs, and Look-Alikes

At a Glance

Hemorrhoids commonly cause bright red bleeding, itching, pain, or a lump, but anal fissures, inflammatory bowel disease, and colorectal cancer can look similar. Heavy bleeding, black stool, blood mixed into stool, weight loss, bowel changes, or persistent pain need prompt medical evaluation.

When you notice rectal bleeding or discomfort, it is common to assume hemorrhoids are the cause. While they are a very frequent source of these symptoms, several other conditions can look similar but require different treatments. Understanding the nuances of your symptoms can help you have a more productive conversation with your doctor and ensure nothing more serious is overlooked [1][2].

URGENT CARE WARNING: Seek emergency medical care if you experience heavy or persistent rectal bleeding, pass blood clots or black/tarry stool, feel lightheaded, dizzy or faint, have severe abdominal pain, or develop a fever.

Hallmark Symptoms of Hemorrhoids

Hemorrhoids are swollen veins in the lower rectum and anus. Their symptoms depend largely on whether they are internal or external.

Internal Hemorrhoids

These develop inside the rectum, above the dentate line (the boundary between the sensitive skin of the anal canal and the less sensitive lining of the rectum) [3][4].

  • Painless Bleeding: This is the most common sign. You may see bright red blood on the toilet paper or in the toilet bowl after a bowel movement [3][5]. Note that if internal hemorrhoids become severely trapped (strangulated) outside the anus, they can become painful.
  • Prolapse: An internal hemorrhoid may push through the anal opening during a bowel movement. These are graded by their severity:
    • Grade I: No protrusion out of the anus [3].
    • Grade II: Protrudes during a bowel movement but returns inside on its own [5].
    • Grade III: Protrudes and must be manually pushed back in [6].
    • Grade IV: Persistently prolapsed and cannot be pushed back in [3].
  • Mucus and Itching: Prolapsed hemorrhoids can collect small amounts of mucus or stool, which can irritate the skin and cause itching (pruritus ani) [6][7].

External Hemorrhoids

These are located under the skin around the anus, below the dentate line. Because this area has many pain-sensing nerves, external hemorrhoids behave differently [4].

  • Pain and Swelling: They often feel like a tender lump. Unlike internal hemorrhoids, they can be quite painful, especially when sitting or during physical activity [6][8].
  • Thrombosis: If blood pools in an external hemorrhoid and forms a clot (thrombosis), it can cause sudden, severe pain and a firm, bluish lump [3][8].

When It’s Not Hemorrhoids: Red Flags

While hemorrhoids are common, they can mask or coexist with more serious conditions like Colorectal Cancer (CRC) or Inflammatory Bowel Disease (IBD), such as Crohn’s disease or ulcerative colitis [9][10]. Keep in mind that cancer is not the most likely explanation for every anal symptom, but any new or unexplained bleeding still requires evaluation.

The following “red flag” symptoms should be discussed with a doctor promptly:

  • Blood Characteristics: While hemorrhoids typically cause bright red blood, darker blood or blood mixed into the stool may suggest a source higher up in the colon [9][11]. However, bright red blood can also be caused by cancer or IBD, so color alone is not a guarantee of safety.
  • Changed Bowel Habits: Any persistent change in your routine (diarrhea, constipation, or narrowing of the stool) that lasts more than a few weeks warrants investigation [9][12].
  • Unexplained Weight Loss: Losing weight without trying can be a systemic sign of IBD or cancer [9][13].
  • Persistent Abdominal Pain: Frequent cramping or pain in the belly is not typical of hemorrhoids and warrants investigation [12][10].
  • Anemia or Fatigue: If you feel unusually tired or short of breath, chronic blood loss (even if you don’t see much) may have led to anemia (low red blood cell count) [1][14].

Differentiating the “Look-Alikes”

Several other conditions occur in the same area and are frequently mistaken for hemorrhoids.

Anal Fissure

An anal fissure is a small tear in the lining of the anal canal.

  • The Pain Difference: Unlike the dull ache of hemorrhoids, a fissure causes sharp, “tearing,” or “knife-like” pain specifically during and after a bowel movement [15][16].
  • Bleeding: Like hemorrhoids, fissures can cause bright red blood on the toilet paper, but the intense pain is the distinguishing feature [16][17].

Proctitis

Proctitis is inflammation of the lining of the rectum.

  • Symptoms: It can cause a frequent urge to have a bowel movement (tenesmus), mucus or pus discharge, and rectal bleeding [18][19]. It is often associated with IBD or infections.

Anal Cancer

Though rare, anal cancer can mimic benign conditions.

  • Signs to Watch: A mass that you can feel, a non-healing ulcer, or persistent itching and discharge that does not improve with standard hemorrhoid treatments should be evaluated by a specialist [19].
Symptom Hemorrhoids Anal Fissure IBD / Proctitis Colorectal Cancer
Pain Dull ache (External) or Painless (Internal, unless trapped) Sharp, tearing during BM Cramping, urgency Often painless early on
Blood Color Bright red Bright red Bright or dark; may have mucus Can be dark/maroon, but bright red is also possible
Stool Changes Usually none Constipation (due to pain) Diarrhea, urgency May have narrowing or habit change

The Importance of a Professional Exam

Because symptoms overlap significantly, a physical exam is essential. Your doctor may perform a Digital Rectal Exam (DRE) or use an Anoscope (a small tube to look inside the anal canal) to see exactly what is causing the symptoms [3][14]. If you have red flags, your doctor may recommend a colonoscopy or other evaluation to view the entire colon [20][21]. Never assume bleeding is “just hemorrhoids” without a professional evaluation, especially if symptoms persist [22][2].

Common questions in this guide

What does bleeding from hemorrhoids usually look like?
Internal hemorrhoids commonly cause painless, bright red blood on toilet paper or in the toilet bowl after a bowel movement. Dark or maroon blood or blood mixed into stool warrants prompt medical evaluation rather than assuming hemorrhoids. Heavy or persistent bleeding, clots, black or tarry stool, or bleeding with dizziness or fainting needs emergency care.
How are hemorrhoids different from an anal fissure?
An anal fissure is a small tear and usually causes sharp, tearing pain during and after a bowel movement. Hemorrhoids more often cause painless bright red bleeding when internal, or a tender lump, swelling, or pressure when external. A clinician can distinguish them with an examination.
Which symptoms suggest rectal bleeding may be caused by something other than hemorrhoids?
Persistent changes in bowel habits, blood mixed with stool, unexplained weight loss, ongoing abdominal pain, or unusual fatigue or shortness of breath are not typical of uncomplicated hemorrhoids. They can occur with inflammatory bowel disease or colorectal cancer, although these symptoms have other possible causes. They should be discussed with a clinician.
When should rectal bleeding be treated as an emergency?
An urgent evaluation is needed for heavy or persistent rectal bleeding, blood clots, black or tarry stool, lightheadedness, dizziness, fainting, severe abdominal pain, or fever. These signs can indicate significant bleeding or another condition that needs prompt treatment.
What tests can a doctor use to find the cause of rectal bleeding?
A clinician may start with a physical examination, including a digital rectal exam, and may use an anoscope to inspect the anal canal. If symptoms or red flags suggest a problem higher in the bowel, a colonoscopy or another evaluation may be recommended. The choice depends on your symptoms, medical history, and examination.
Which specialist should I see for persistent hemorrhoid-like symptoms?
Ask your primary clinician whether the bleeding pattern fits hemorrhoids and whether you need further testing. A gastroenterologist or colorectal surgeon may provide more specialized evaluation when symptoms persist, the diagnosis is unclear, or red flags are present.

Get notified when new evidence is published on hemorrhoid.

We monitor PubMed for new peer-reviewed studies on this topic and email a short summary when something meaningful changes.

References

References (22)
  1. 1

    Colonoscopic Evaluation of Lower Gastrointestinal Bleeding (LGIB): Practical Approach.

    Matkovic Z, Zildzic M

    Medical archives (Sarajevo, Bosnia and Herzegovina) 2021; (75(4)):274-279 doi:10.5455/medarh.2021.75.274-279.

    PMID: 34759447
  2. 2

    Evaluating the Accuracy of Hemorrhoids: Comparison Among Specialties and Symptoms.

    Idrees JJ, Clapp M, Brady JT, et al.

    Diseases of the colon and rectum 2019; (62(7)):867-871 doi:10.1097/DCR.0000000000001315.

    PMID: 31188188
  3. 3

    Hemorrhoidal Disease: A Review.

    Ashburn JH

    JAMA 2025; doi:10.1001/jama.2025.13083.

    PMID: 40824576
  4. 4

    Upper border of anal transitional zone: a new landmark for endoscopic internal hemorrhoid therapy.

    Li J, Li H, Xu H, et al.

    Frontiers in medicine 2026; (13()):1903391 doi:10.3389/fmed.2026.1903391.

    PMID: 42757278
  5. 5

    Treatment of hemorrhoids: A coloproctologist's view.

    Lohsiriwat V

    World journal of gastroenterology 2015; (21(31)):9245-52 doi:10.3748/wjg.v21.i31.9245.

    PMID: 26309351
  6. 6

    AGA Clinical Practice Update on Diagnosis and Treatment of Hemorrhoids: Expert Review.

    Qureshi W, Hoang S, Frye J, Rao SS

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2026; (24(7)):1773-1781 doi:10.1016/j.cgh.2026.04.008.

    PMID: 42067175
  7. 7

    Prevalence of Hemorrhoids and Their Risk Factors Among the Adult Population in Jazan, Saudi Arabia.

    Oberi IA, Omar Y, Alfaifi AJ, et al.

    Cureus 2023; (15(9)):e45919 doi:10.7759/cureus.45919.

    PMID: 37885500
  8. 8

    A rare cause of acute anal pain: strangulated hemorrhoids in a perianal fistula.

    Yigit D, Turan MI, Akgul N

    Annali italiani di chirurgia 2022; (11()).

    PMID: 37070227
  9. 9

    Hemorrhoids and Rectal Cancer: A Systematic Review of Clinical Overlap, Diagnostic Misclassification, and Early Detection Strategies for Primary Care.

    Tu M, Jiang W, Huang Y

    Journal of multidisciplinary healthcare 2026; (19()):638033 doi:10.2147/JMDH.S638033.

    PMID: 42699804
  10. 10

    Hemorrhoids and anal fissures in inflammatory bowel disease.

    D'Ugo S, Stasi E, Gaspari AL, Sileri P

    Minerva gastroenterologica e dietologica 2015; (61(4)):223-33.

    PMID: 26446683
  11. 11

    British Society of Gastroenterology: diagnosis and management of acute lower gastrointestinal bleeding.

    Bond A, Smith PJ

    Frontline gastroenterology 2019; (10(4)):417-420 doi:10.1136/flgastro-2019-101220.

    PMID: 31656568
  12. 12

    Predictive values for different cancers and inflammatory bowel disease of 6 common abdominal symptoms among more than 1.9 million primary care patients in the UK: A cohort study.

    Herbert A, Rafiq M, Pham TM, et al.

    PLoS medicine 2021; (18(8)):e1003708 doi:10.1371/journal.pmed.1003708.

    PMID: 34339405
  13. 13

    Disease patterns among Saudi children undergoing colonoscopy for lower gastrointestinal bleeding: Single tertiary care center experience.

    Alrashidi S, AlAmery T, Alshanbary A, et al.

    Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 2023; (29(6)):388-395 doi:10.4103/sjg.sjg_130_23.

    PMID: 37706419
  14. 14

    Colorectal Cancer Fast Tracks: Cancer Yield and the Predictive Value of Entry Criteria.

    Uebel L, Kromodikoro I, Nyhlin N, van Nieuwenhoven M

    Cancers 2023; (15(19)) doi:10.3390/cancers15194778.

    PMID: 37835472
  15. 15

    Conservative Treatment of Hemorrhoidal Disease.

    Stratta E, Gallo G, Trompetto M

    Reviews on recent clinical trials 2021; (16(1)):87-90 doi:10.2174/1574887115666201021150144.

    PMID: 33087033
  16. 16

    [Anal fissure].

    Fathallah N, Spindler L, Zeitoun JD, De Parades V

    La Revue du praticien 2019; (69(9)):1005-1010.

    PMID: 32237626
  17. 17

    Are We Overdoing Pediatric Lower Gastrointestinal Endoscopy?

    Kawada PS, O'Loughlin EV, Stormon MO, et al.

    Journal of pediatric gastroenterology and nutrition 2017; (64(6)):898-902 doi:10.1097/MPG.0000000000001192.

    PMID: 26960173
  18. 18

    [Rectal bleeding: easy to overcome or still a challenge in proctology?]

    Schwandner O, Pech O

    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 2019; (90(8)):640-647 doi:10.1007/s00104-019-0944-y.

    PMID: 30911796
  19. 19

    A Case Series of Anal Carcinoma Misdiagnosed as Idiopathic Chronic Anal Fissure.

    Barbeiro S, Atalaia-Martins C, Marcos P, et al.

    GE Portuguese journal of gastroenterology 2017; (24(5)):227-231 doi:10.1159/000452869.

    PMID: 29255757
  20. 20

    The role of colonoscopy in young patients with rectal bleeding: a systematic review and meta-analysis.

    Colles T, Ziegelmann PK, Damin DC

    International journal of colorectal disease 2023; (38(1)):230 doi:10.1007/s00384-023-04524-4.

    PMID: 37712988
  21. 21

    Outcomes and performance of risk scores in acute lower gastrointestinal bleeding.

    Saleepol A, Kaosombatwattana U

    JGH open : an open access journal of gastroenterology and hepatology 2023; (7(5)):372-376 doi:10.1002/jgh3.12907.

    PMID: 37265927
  22. 22

    The Emborrhoid Technique for Treatment of Bleeding Hemorrhoids in Patients with High Surgical Risk.

    Campennì P, Iezzi R, Marra AA, et al.

    Journal of clinical medicine 2022; (11(19)) doi:10.3390/jcm11195533.

    PMID: 36233395

This page is for informational purposes only and does not constitute medical advice. Because hemorrhoid symptoms can resemble fissures, inflammatory bowel disease, or cancer, consult a healthcare professional about persistent or unexplained bleeding.