Research & Literature

Treatment of hemorrhoids: A coloproctologist's view.

Lohsiriwat V

World journal of gastroenterology 2015; (21(31)):9245-52 doi:10.3748/wjg.v21.i31.9245.

Risk Factors for Hemorrhoids on Screening Colonoscopy.

Peery AF, Sandler RS, Galanko JA, et al.

PloS one 2015; (10(9)):e0139100 doi:10.1371/journal.pone.0139100.

Systematic review and network meta-analysis comparing clinical outcomes and effectiveness of surgical treatments for haemorrhoids.

Simillis C, Thoukididou SN, Slesser AA, et al.

The British journal of surgery 2015; (102(13)):1603-18 doi:10.1002/bjs.9913.

Hemorrhoids and anal fissures in inflammatory bowel disease.

D'Ugo S, Stasi E, Gaspari AL, Sileri P

Minerva gastroenterologica e dietologica 2015; (61(4)):223-33.

[Meta-analysis of randomized controlled trials comparing procedure for prolapse and hemorrhoids with Milligan-Morgan hemorrhoidectomy in the treatment of prolapsed hemorrhoids].

He P, Chen H

Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 2015; (18(12)):1224-30.

Are We Overdoing Pediatric Lower Gastrointestinal Endoscopy?

Kawada PS, O'Loughlin EV, Stormon MO, et al.

Journal of pediatric gastroenterology and nutrition 2017; (64(6)):898-902 doi:10.1097/MPG.0000000000001192.

Clinical acceptability study of micronized purified flavonoid fraction 1000 mg tablets versus 500 mg tablets in patients suffering acute hemorrhoidal disease.

Shelygin Y, Krivokapic Z, Frolov SA, et al.

Current medical research and opinion 2016; (32(11)):1821-1826 doi:10.1080/03007995.2016.1211520.

Anal Health Care Basics.

Chang J, Mclemore E, Tejirian T

The Permanente journal 2016; (20(4)):15-222 doi:10.7812/TPP/15-222.

Adequate dietary fiber supplement and TONE can help avoid surgery in most patients with advanced hemorrhoids.

Garg P, Singh P

Minerva gastroenterologica e dietologica 2017; (63(2)):92-96 doi:10.23736/S1121-421X.17.02364-9.

The non-surgical management for hemorrhoidal disease. A systematic review.

Cocorullo G, Tutino R, Falco N, et al.

Il Giornale di chirurgia 2017; (38(1)):5-14 doi:10.11138/gchir/2017.38.1.005.

Colorectal Cancer Screening: Recommendations for Physicians and Patients from the U.S. Multi-Society Task Force on Colorectal Cancer.

Rex DK, Boland CR, Dominitz JA, et al.

The American journal of gastroenterology 2017; (112(7)):1016-1030 doi:10.1038/ajg.2017.174.

Transanal hemorrhoidal dearterialization (THD) for hemorrhoidal disease: a single-center study on 1000 consecutive cases and a review of the literature.

Ratto C, Campennì P, Papeo F, et al.

Techniques in coloproctology 2017; (21(12)):953-962 doi:10.1007/s10151-017-1726-5.

A Case Series of Anal Carcinoma Misdiagnosed as Idiopathic Chronic Anal Fissure.

Barbeiro S, Atalaia-Martins C, Marcos P, et al.

GE Portuguese journal of gastroenterology 2017; (24(5)):227-231 doi:10.1159/000452869.

Hemorrhoids: Diagnosis and Treatment Options.

Mott T, Latimer K, Edwards C

American family physician 2018; (97(3)):172-179.

Endometriosis in the rectum accompanied by hemorrhoids leading to diagnostic pitfalls: a rare case report.

Shi X, Fan C

BMC women's health 2018; (18(1)):120 doi:10.1186/s12905-018-0615-z.

Transanal hemorrhoidal dearterialization (THD) versus stapled hemorrhoidopexy (SH) in treatment of internal hemorrhoids: a systematic review and meta-analysis of randomized clinical trials.

Emile SH, Elfeki H, Sakr A, Shalaby M

International journal of colorectal disease 2019; (34(1)):1-11 doi:10.1007/s00384-018-3187-3.

[Rectal bleeding: easy to overcome or still a challenge in proctology?]

Schwandner O, Pech O

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 2019; (90(8)):640-647 doi:10.1007/s00104-019-0944-y.

Transanal hemorrhoidal dearterialization versus Milligan-Morgan hemorrhoidectomy in grade III/IV hemorrhoids.

Genova P, Damiano G, Lo Monte AI, Genova G

Annali italiani di chirurgia 2019; (90()):145-151.

Evaluating the Accuracy of Hemorrhoids: Comparison Among Specialties and Symptoms.

Idrees JJ, Clapp M, Brady JT, et al.

Diseases of the colon and rectum 2019; (62(7)):867-871 doi:10.1097/DCR.0000000000001315.

Hemorrhoid management in women: the role of tribenoside + lidocaine.

Kestřánek J

Drugs in context 2019; (8()):212602 doi:10.7573/dic.212602.

Japanese Practice Guidelines for Anal Disorders I. Hemorrhoids.

Yamana T

Journal of the anus, rectum and colon 2017; (1(3)):89-99 doi:10.23922/jarc.2017-018.

British Society of Gastroenterology: diagnosis and management of acute lower gastrointestinal bleeding.

Bond A, Smith PJ

Frontline gastroenterology 2019; (10(4)):417-420 doi:10.1136/flgastro-2019-101220.

Video anoscopy: results of routine anal examination during colonoscopies.

Gomes A, Minata MK, Jukemura J, de Moura EGH

Endoscopy international open 2019; (7(11)):E1549-E1562 doi:10.1055/a-0998-3958.

Treatment of hemorrhoids: A survey of surgical practice in Australia and New Zealand.

Fowler GE, Siddiqui J, Zahid A, Young CJ

World journal of clinical cases 2019; (7(22)):3742-3750 doi:10.12998/wjcc.v7.i22.3742.

[Differential diagnosis of hemorrhoidal disease].

Herold A

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 2020; (71(4)):269-274 doi:10.1007/s00105-020-04553-y.

[Choice of optimal treatment strategy for acute perianal thrombosis. Results of online survey].

Garmanova TN, Bredikhin MI, Tulina IA, et al.

Khirurgiia 2020; 39-47 doi:10.17116/hirurgia202002139.

Treatment of haemorrhoidal disease with micronized purified flavonoid fraction and sucralfate ointment.

Amaturo A, Meucci M, Mari FS

Acta bio-medica : Atenei Parmensis 2020; (91(1)):139-141 doi:10.23750/abm.v91i1.9361.

[Anal fissure].

Fathallah N, Spindler L, Zeitoun JD, De Parades V

La Revue du praticien 2019; (69(9)):1005-1010.

Micronized Purified Flavonoid Fraction in Hemorrhoid Disease: A Systematic Review and Meta-Analysis.

Sheikh P, Lohsiriwat V, Shelygin Y

Advances in therapy 2020; (37(6)):2792-2812 doi:10.1007/s12325-020-01353-7.

TRANSANAL HAEMORRHOIDAL DEARTERIALIZATION WITH MUCOPEXY (THD-M) FOR TREATMENT OF HEMORRHOIDS: IS IT APPLICABLE IN ALL GRADES? BRAZILIAN MULTICENTER STUDY.

Sobrado CW, Klajner S, Hora JAB, et al.

Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery 2020; (33(2)):e1504 doi:10.1590/0102-672020190001e1504.

Conservative Treatment of Hemorrhoidal Disease.

Stratta E, Gallo G, Trompetto M

Reviews on recent clinical trials 2021; (16(1)):87-90 doi:10.2174/1574887115666201021150144.

Belgian consensus guideline on the management of hemorrhoidal disease.

De Schepper H, Coremans G, Denis MA, et al.

Acta gastro-enterologica Belgica 2021; (84(1)):101-120 doi:10.51821/84.1.497.

A Prospective Study on the Efficacy of Two Different Phlebotonic Therapies as a Bridge to Surgery in Patients with Advanced Hemorrhoidal Disease.

Orefice R, Litta F, Parello A, et al.

Journal of clinical medicine 2021; (10(8)) doi:10.3390/jcm10081549.

Predictive values for different cancers and inflammatory bowel disease of 6 common abdominal symptoms among more than 1.9 million primary care patients in the UK: A cohort study.

Herbert A, Rafiq M, Pham TM, et al.

PLoS medicine 2021; (18(8)):e1003708 doi:10.1371/journal.pmed.1003708.

Colorectal Cancer Risk in Patients with Hemorrhoids: A 10-Year Population-Based Retrospective Cohort Study.

Wu EB, Sung FC, Lin CL, et al.

International journal of environmental research and public health 2021; (18(16)) doi:10.3390/ijerph18168655.

Colonoscopic Evaluation of Lower Gastrointestinal Bleeding (LGIB): Practical Approach.

Matkovic Z, Zildzic M

Medical archives (Sarajevo, Bosnia and Herzegovina) 2021; (75(4)):274-279 doi:10.5455/medarh.2021.75.274-279.

Polidocanol Foam Sclerotherapy Versus Rubber Band Ligation in Hemorrhoidal Disease Grades I/II/III: Randomized Trial.

Salgueiro P, Garrido M, Santos RG, et al.

Diseases of the colon and rectum 2022; (65(7)):e718-e727 doi:10.1097/DCR.0000000000002117.

Perianal thrombosis: no need for surgery.

Alldinger I, Poschinski Z, Ganzera S, Helmes C

Langenbeck's archives of surgery 2022; (407(3)):1251-1256 doi:10.1007/s00423-021-02415-2.

Is the Goligher classification a valid tool in clinical practice and research for hemorrhoidal disease?

Dekker L, Han-Geurts IJM, Grossi U, et al.

Techniques in coloproctology 2022; (26(5)):387-392 doi:10.1007/s10151-022-02591-3.

Optimal Strategies for Colorectal Cancer Screening.

Jain S, Maque J, Galoosian A, et al.

Current treatment options in oncology 2022; (23(4)):474-493 doi:10.1007/s11864-022-00962-4.

Efficacy and safety of micronized purified flavonoid fractions for the treatment of postoperative hemorrhoid complications: A systematic review and meta-analysis.

Fu H, Guo W, Zhou B, et al.

Phytomedicine : international journal of phytotherapy and phytopharmacology 2022; (104()):154244 doi:10.1016/j.phymed.2022.154244.

The Emborrhoid Technique for Treatment of Bleeding Hemorrhoids in Patients with High Surgical Risk.

Campennì P, Iezzi R, Marra AA, et al.

Journal of clinical medicine 2022; (11(19)) doi:10.3390/jcm11195533.

Clinical value of alarm features for colorectal cancer: a meta-analysis.

Frazzoni L, Laterza L, La Marca M, et al.

Endoscopy 2023; (55(5)):458-468 doi:10.1055/a-1961-4266.

Office-Based Procedures in the Management of Hemorrhoidal Disease: Rubber Band Ligation versus Sclerotherapy - Systematic Review and Meta-Analysis.

Salgueiro P, Ramos MI, Castro-Poças F, Libânio D

GE Portuguese journal of gastroenterology 2022; (29(6)):409-419 doi:10.1159/000522171.

A rare cause of acute anal pain: strangulated hemorrhoids in a perianal fistula.

Yigit D, Turan MI, Akgul N

Annali italiani di chirurgia 2022; (11()).

Outcomes and performance of risk scores in acute lower gastrointestinal bleeding.

Saleepol A, Kaosombatwattana U

JGH open : an open access journal of gastroenterology and hepatology 2023; (7(5)):372-376 doi:10.1002/jgh3.12907.

Treatment of haemorrhoids in pregnancy: A retrospective review.

Fiordaliso M, De Marco FA, D'Alessandro V, et al.

Annali italiani di chirurgia 2023; (94()):274-280.

Colonoscopy in the young: An indication-based analysis of outcome.

Abu Baker F, Samhat A, Taher Natour R, et al.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2023; (71(8)):797-803 doi:10.1177/10815589231193953.

Disease patterns among Saudi children undergoing colonoscopy for lower gastrointestinal bleeding: Single tertiary care center experience.

Alrashidi S, AlAmery T, Alshanbary A, et al.

Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 2023; (29(6)):388-395 doi:10.4103/sjg.sjg_130_23.

The role of colonoscopy in young patients with rectal bleeding: a systematic review and meta-analysis.

Colles T, Ziegelmann PK, Damin DC

International journal of colorectal disease 2023; (38(1)):230 doi:10.1007/s00384-023-04524-4.

Colorectal Cancer Fast Tracks: Cancer Yield and the Predictive Value of Entry Criteria.

Uebel L, Kromodikoro I, Nyhlin N, van Nieuwenhoven M

Cancers 2023; (15(19)) doi:10.3390/cancers15194778.

Prevalence of Hemorrhoids and Their Risk Factors Among the Adult Population in Jazan, Saudi Arabia.

Oberi IA, Omar Y, Alfaifi AJ, et al.

Cureus 2023; (15(9)):e45919 doi:10.7759/cureus.45919.

Effects of early warm water sitz bath on urinary retention and pain after haemorrhoidectomy: A randomized controlled trial.

Liao WC, Cheng YY, Hsu CK, et al.

International journal of nursing studies 2024; (154()):104765 doi:10.1016/j.ijnurstu.2024.104765.

The Italian Unitary Society of Colon-Proctology (Società Italiana Unitaria di Colonproctologia) guidelines for the management of acute and chronic hemorrhoidal disease.

Brillantino A, Renzi A, Talento P, et al.

Annals of coloproctology 2024; (40(4)):287-320 doi:10.3393/ac.2023.00871.0124.

The Value of Colonoscopy in Assessing Rectal Bleeding in Patients Referred From Outpatient Care Units in Erbil, Iraq.

Haweizy R, Qader FN

Cureus 2024; (16(10)):e71911 doi:10.7759/cureus.71911.

Clinical evidence and rationale of topical nifedipine and lidocaine ointment in the treatment of anal fissure and hemorrhoidal disease.

Gallo G, Trompetto M

Minerva surgery 2025; (80(2)):177-192 doi:10.23736/S2724-5691.25.10771-5.

Operative versus nonoperative treatment of thrombosed external hemorrhoids: a systematic review and meta-analysis.

Martins MAB, Almeida LFC, Cappellaro AP, et al.

Updates in surgery 2026; (78(1)):169-175 doi:10.1007/s13304-025-02302-1.

Hemorrhoidal Disease: A Review.

Ashburn JH

JAMA 2025; doi:10.1001/jama.2025.13083.

Rubber Band Ligation: A New Treatment Option for External Hemorrhoids.

Sadik D, St-Onge JF, St-Onge F, et al.

Cureus 2025; (17(8)):e89701 doi:10.7759/cureus.89701.

Open excisional haemorrhoidectomy versus transanal haemorrhoidal dearterialization for grade III haemorrhoids: open-label randomized clinical trial.

Fernandez-Hurtado I, Pages-Valle N, Sarubbo MF, et al.

The British journal of surgery 2025; (113(1)) doi:10.1093/bjs/znaf282.

AGA Clinical Practice Update on Diagnosis and Treatment of Hemorrhoids: Expert Review.

Qureshi W, Hoang S, Frye J, Rao SS

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2026; (24(7)):1773-1781 doi:10.1016/j.cgh.2026.04.008.

Defining proficiency in THD-Anolift: a CUSUM analysis of the learning curve in 51 consecutive cases.

Galli AC, Dionigi G, Lauricella S, et al.

International journal of colorectal disease 2026; (41(1)).

Hemorrhoids and Rectal Cancer: A Systematic Review of Clinical Overlap, Diagnostic Misclassification, and Early Detection Strategies for Primary Care.

Tu M, Jiang W, Huang Y

Journal of multidisciplinary healthcare 2026; (19()):638033 doi:10.2147/JMDH.S638033.

Upper border of anal transitional zone: a new landmark for endoscopic internal hemorrhoid therapy.

Li J, Li H, Xu H, et al.

Frontiers in medicine 2026; (13()):1903391 doi:10.3389/fmed.2026.1903391.