Research & Literature

Car Crashes and Central Disorders of Hypersomnolence: A French Study.

Pizza F, Jaussent I, Lopez R, et al.

PloS one 2015; (10(6)):e0129386 doi:10.1371/journal.pone.0129386.

Central Disorders of Hypersomnolence: Focus on the Narcolepsies and Idiopathic Hypersomnia.

Khan Z, Trotti LM

Chest 2015; (148(1)):262-273 doi:10.1378/chest.14-1304.

What Does One Sleep-Onset REM Period—During Either Nocturnal Polysomnography or Multiple Sleep Latency Test—Mean in Differential Diagnosis of Central Hypersomnias?

Bozluolcay M, Nalbantoglu M, Benbir Senel G, Karadeniz D

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society 2015; (32(4)):364-8 doi:10.1097/WNP.0000000000000192.

Idiopathic hypersomnia.

Billiard M, Sonka K

Sleep medicine reviews 2016; (29()):23-33.

Behavioral Sleep Medicine Services for Hypersomnia Disorders: A Survey Study.

Neikrug AB, Crawford MR, Ong JC

Behavioral sleep medicine 2017; (15(2)):158-171 doi:10.1080/15402002.2015.1120201.

Absence of γ-aminobutyric acid-a receptor potentiation in central hypersomnolence disorders.

Dauvilliers Y, Evangelista E, Lopez R, et al.

Annals of neurology 2016; (80(2)):259-68 doi:10.1002/ana.24710.

Waking up is the hardest thing I do all day: Sleep inertia and sleep drunkenness.

Trotti LM

Sleep medicine reviews 2017; (35()):76-84 doi:10.1016/j.smrv.2016.08.005.

French consensus. Idiopathic hypersomnia: Investigations and follow-up.

Leu-Semenescu S, Quera-Salva MA, Dauvilliers Y

Revue neurologique 2017; (173(1-2)):32-37 doi:10.1016/j.neurol.2016.09.015.

Test-Retest Reliability of the Multiple Sleep Latency Test in Central Disorders of Hypersomnolence.

Lopez R, Doukkali A, Barateau L, et al.

Sleep 2017; (40(12)) doi:10.1093/sleep/zsx164.

The MSLT is Repeatable in Narcolepsy Type 1 But Not Narcolepsy Type 2: A Retrospective Patient Study.

Ruoff C, Pizza F, Trotti LM, et al.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2018; (14(1)):65-74 doi:10.5664/jcsm.6882.

Alternative diagnostic criteria for idiopathic hypersomnia: A 32-hour protocol.

Evangelista E, Lopez R, Barateau L, et al.

Annals of neurology 2018; (83(2)):235-247 doi:10.1002/ana.25141.

Ability of the Multisensory Jawbone UP3 to Quantify and Classify Sleep in Patients With Suspected Central Disorders of Hypersomnolence: A Comparison Against Polysomnography and Actigraphy.

Cook JD, Prairie ML, Plante DT

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2018; (14(5)):841-848 doi:10.5664/jcsm.7120.

Measurement of symptoms in idiopathic hypersomnia: The Idiopathic Hypersomnia Severity Scale.

Dauvilliers Y, Evangelista E, Barateau L, et al.

Neurology 2019; (92(15)):e1754-e1762 doi:10.1212/WNL.0000000000007264.

Optimizing Actigraphic Estimation of Sleep Duration in Suspected Idiopathic Hypersomnia.

Cook JD, Eftekari SC, Leavitt LA, et al.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2019; (15(4)):597-602 doi:10.5664/jcsm.7722.

The multiple sleep latency test.

Arand DL, Bonnet MH

Handbook of clinical neurology 2019; (160()):393-403 doi:10.1016/B978-0-444-64032-1.00026-6.

Clinical neurophysiology of CNS hypersomnias.

Barateau L, Lopez R, Dauvilliers Y

Handbook of clinical neurology 2019; (161()):353-367 doi:10.1016/B978-0-444-64142-7.00060-6.

Precision Medicine for Idiopathic Hypersomnia.

Arnulf I, Leu-Semenescu S, Dodet P

Sleep medicine clinics 2019; (14(3)):333-350 doi:10.1016/j.jsmc.2019.05.007.

To split or to lump? Classifying the central disorders of hypersomnolence.

Fronczek R, Arnulf I, Baumann CR, et al.

Sleep 2020; (43(8)) doi:10.1093/sleep/zsaa044.

Multimodal assessment increases objective identification of hypersomnolence in patients referred for multiple sleep latency testing.

Plante DT, Cook JD, Prairie ML

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2020; (16(8)):1241-1248 doi:10.5664/jcsm.8470.

Developing a cognitive behavioral therapy for hypersomnia using telehealth: a feasibility study.

Ong JC, Dawson SC, Mundt JM, Moore C

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2020; (16(12)):2047-2062 doi:10.5664/jcsm.8750.

Disease symptomatology and response to treatment in people with idiopathic hypersomnia: initial data from the Hypersomnia Foundation registry.

Trotti LM, Ong JC, Plante DT, et al.

Sleep medicine 2020; (75()):343-349 doi:10.1016/j.sleep.2020.08.034.

Characteristics associated with hypersomnia and excessive daytime sleepiness identified by extended polysomnography recording.

Evangelista E, Rassu AL, Barateau L, et al.

Sleep 2021; (44(5)) doi:10.1093/sleep/zsaa264.

Efficacy and safety of modafinil in patients with idiopathic hypersomnia without long sleep time: a multicenter, randomized, double-blind, placebo-controlled, parallel-group comparison study.

Inoue Y, Tabata T, Tsukimori N

Sleep medicine 2021; (80()):315-321 doi:10.1016/j.sleep.2021.01.018.

Actigraphy prior to Multiple Sleep Latency Test: nighttime total sleep time predicts sleep-onset latency.

Kelly MR, Zeidler MR, DeCruz S, et al.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2022; (18(1)):161-170 doi:10.5664/jcsm.9528.

Safety and efficacy of lower-sodium oxybate in adults with idiopathic hypersomnia: a phase 3, placebo-controlled, double-blind, randomised withdrawal study.

Dauvilliers Y, Arnulf I, Foldvary-Schaefer N, et al.

The Lancet. Neurology 2022; (21(1)):53-65 doi:10.1016/S1474-4422(21)00368-9.

Precision Medicine for Idiopathic Hypersomnia.

Arnulf I, Leu-Semenescu S, Dodet P

Sleep medicine clinics 2022; (17(3)):379-398 doi:10.1016/j.jsmc.2022.06.016.

Clinical considerations for the diagnosis of idiopathic hypersomnia.

Dauvilliers Y, Bogan RK, Arnulf I, et al.

Sleep medicine reviews 2022; (66()):101709 doi:10.1016/j.smrv.2022.101709.

Differentiation of central disorders of hypersomnolence with manual and artificial-intelligence-derived polysomnographic measures.

Cesari M, Egger K, Stefani A, et al.

Sleep 2023; (46(2)) doi:10.1093/sleep/zsac288.

What respiratory physicians should know about narcolepsy and other hypersomnias.

Klaus S, Carolan A, O'Rourke D, Kennedy B

Breathe (Sheffield, England) 2022; (18(3)):220157 doi:10.1183/20734735.0157-2022.

Update on the treatment of idiopathic hypersomnia: Progress, challenges, and expert opinion.

Arnulf I, Thomas R, Roy A, Dauvilliers Y

Sleep medicine reviews 2023; (69()):101766 doi:10.1016/j.smrv.2023.101766.

Symptom Severity and Treatment Satisfaction in Patients with Idiopathic Hypersomnia: The Real World Idiopathic Hypersomnia Outcomes Study (ARISE).

Schneider LD, Stevens J, Husain AM, et al.

Nature and science of sleep 2023; (15()):89-101 doi:10.2147/NSS.S386021.

Narcolepsy and Idiopathic Hypersomnia.

Blattner M, Maski K

Sleep medicine clinics 2023; (18(2)):183-199 doi:10.1016/j.jsmc.2023.01.003.

Long-term efficacy and safety of low-sodium oxybate in an open-label extension period of a placebo-controlled, double-blind, randomized withdrawal study in adults with idiopathic hypersomnia.

Morse AM, Dauvilliers Y, Arnulf I, et al.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2023; (19(10)):1811-1822 doi:10.5664/jcsm.10698.

Repeated polysomnography and multiple sleep latency test in narcolepsy type 1 and other hypersomnolence disorders.

Torstensen EW, Haubjerg Østerby NC, Kornum BR, et al.

Sleep medicine 2023; (110()):91-98 doi:10.1016/j.sleep.2023.07.029.

Impairment in Functioning and Quality of Life in Patients with Idiopathic Hypersomnia: The Real World Idiopathic Hypersomnia Outcomes Study (ARISE).

Stevens J, Schneider LD, Husain AM, et al.

Nature and science of sleep 2023; (15()):593-606 doi:10.2147/NSS.S396641.

Idiopathic hypersomnia years after the diagnosis.

Šonka K, Feketeová E, Nevšímalová S, et al.

Journal of sleep research 2024; (33(2)):e14011 doi:10.1111/jsr.14011.

Idiopathic hypersomnia and Kleine-Levin syndrome.

Arnulf I, Dodet P, Leu-Semenescu S, Maranci JB

Revue neurologique 2023; (179(7)):741-754 doi:10.1016/j.neurol.2023.08.010.

Unrefreshing naps and sleep architecture during the multiple sleep latency test in idiopathic hypersomnia.

Mombelli S, Deshaies-Rugama AS, Blais H, et al.

Journal of sleep research 2025; (34(1)):e14261 doi:10.1111/jsr.14261.

A scoping review of the evidence on pharmacological and nonpharmacological interventions for idiopathic hypersomnia.

Saini V, Saini S

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2024; (20(10)):1685-1704 doi:10.5664/jcsm.11250.

Insights from a 10-year Australasian idiopathic hypersomnia patient data registry study.

Anderson J, Yee BJ, Grunstein R, et al.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2024; (20(12)):1955-1964 doi:10.5664/jcsm.11298.

Diagnostic challenges and burden of idiopathic hypersomnia: a systematic literature review.

Boulanger T, Pigeon P, Crawford S

Sleep advances : a journal of the Sleep Research Society 2024; (5(1)):zpae059 doi:10.1093/sleepadvances/zpae059.

Patient experiences of narcolepsy and idiopathic hypersomnia in the Nordics: a patient journey map.

Vesinurm M, Dünweber C, Rimestad J, et al.

Journal of sleep research 2025; (34(3)):e14376 doi:10.1111/jsr.14376.

Social support and isolation in narcolepsy and idiopathic hypersomnia: An international survey.

Flygare J, Oglesby L, Parthasarathy S, et al.

Sleep medicine 2025; (125()):65-73 doi:10.1016/j.sleep.2024.11.013.

Validation of the Idiopathic Hypersomnia Severity Scale in the Czech Republic.

Bušková J, Miletínová E, Dvořáková T, et al.

Prague medical report 2024; (125(4)):289-301 doi:10.14712/23362936.2024.26.

The impact of idiopathic hypersomnia on the social lives of young adults.

Davidson RD, Blattner M, Scammell TE, Zhou ES

Sleep health 2025; (11(1)):113-119 doi:10.1016/j.sleh.2024.10.006.

Quality of life and its associates in narcolepsy 1 and 2 types and idiopathic hypersomnia.

Galušková K, Nevšímalová S, Příhodová I, et al.

Sleep medicine 2025; (129()):31-39 doi:10.1016/j.sleep.2025.02.019.

A case study of acceptance and commitment therapy for central disorders of hypersomnolence: opportunities to improve patient-centered and comprehensive treatment approaches.

Roth AJ, Foldvary-Schaefer N

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2025; (21(7)):1301-1304 doi:10.5664/jcsm.11634.

A minimal clinically important difference for the sleep inertia visual analog scale in idiopathic hypersomnia.

Bogan RK, Fuller DS, Whalen M, et al.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2025; (21(7)):1209-1216 doi:10.5664/jcsm.11662.

Efficacy and Safety of Sodium Oxybate in Adults With Idiopathic Hypersomnia: A Randomized Controlled Trial.

Dauvilliers Y, Chenini S, Thobois O, et al.

Neurology 2025; (104(11)):e213690 doi:10.1212/WNL.0000000000213690.

Idiopathic hypersomnia symptoms over Time: Longitudinal follow up from the Hypersomnia Foundation registry.

Chattaraj A, Freeman AA, Nichols KJ, et al.

Sleep medicine 2025; (133()):106627 doi:10.1016/j.sleep.2025.106627.

The Clinical and Economic Burden of Idiopathic Hypersomnia: Results from the Real-World Idiopathic Hypersomnia Total Health Model (RHYTHM) Study.

Saad R, Markt SC, Lillaney P, et al.

Nature and science of sleep 2025; (17()):1743-1755 doi:10.2147/NSS.S498432.

Narcolepsy type 2 is an unstable diagnosis and idiopathic hypersomnia has the potential for remission-long-term and cross-sectional observations from the Bern Sleep-Wake Registry.

Cavalli RG, Tamagni AEM, van der Meer J, et al.

Sleep 2026; (49(3)) doi:10.1093/sleep/zsaf242.

Successful Treatment of Secondary Hypersomnia Due to Complex Post-Traumatic Stress Disorder with Eye Movement Desensitization and Reprocessing: A Case Report.

Bucurescu V, Peter-Derex L, Fantini ML, Putois B

Clocks & sleep 2025; (7(3)) doi:10.3390/clockssleep7030043.

Central disorders of hypersomnolence - A narrative review on current and potential biomarkers.

Tai JE, Sivam S, D'Rozario A, et al.

Sleep medicine reviews 2025; (84()):102167 doi:10.1016/j.smrv.2025.102167.

Circadian Modulation of Sleep-Wake Behavior in Patients with Narcolepsy Type 1 and Idiopathic Hypersomnia.

Ryser F, Windirsch AS, Baumann CR, et al.

Nature and science of sleep 2025; (17()):2833-2851 doi:10.2147/NSS.S520647.

Sleep time and SOREMPs features support idiopathic hypersomnia and narcolepsy type 2 as a single disease entity.

Rassu AL, Barateau L, Evangelista E, et al.

Sleep 2025; doi:10.1093/sleep/zsaf378.

Effects of low-sodium oxybate on diary-based sleep time in a clinical study in adults with idiopathic hypersomnia.

Morse AM, Dauvilliers Y, Schneider LD, et al.

Sleep medicine 2026; (138()):108710 doi:10.1016/j.sleep.2025.108710.

Intelligence quotient in adults with idiopathic hypersomnia and narcolepsy type 1.

Zhuang E, Dodet P, Leu-Semenescu S, et al.

Sleep medicine 2026; (140()):108778 doi:10.1016/j.sleep.2026.108778.

Idiopathic hypersomnia is a 24-hour disorder.

Foldvary-Schaefer N, Maski K, Schneider LD, Dauvilliers Y

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 2025; (22(1)):6 doi:10.1007/s44470-025-00007-1.