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PubMed This is a summary of 101 peer-reviewed journal articles Updated

Research & Literature

Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.

Explore the Literature Visualize citation networks across 101 referenced papers

Top Authors

Peter Valent
University of Vienna
Jason Gotlib
Stanford Medicine
Cem Akin
University of Michigan
Jonathan J. Lyons
VA San Diego Healthcare System
Dean D. Metcalfe
National Institute of Allergy and Infectious Diseases
Andreas Reiter
Heidelberg University
Mariana Castells
Brigham and Women's Hospital
Mohamad Jawhar
Heidelberg University

Top Institutions

Ranked by publications Top 10 institutions
03

The University of Texas MD Anderson Cancer Center

Houston, United States

77 papers
06

National Institute of Allergy and Infectious Diseases

Bethesda, United States

96 papers

References

References (101)
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    Pathogenesis and Pathology of Mastocytosis.

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    A distinct biomolecular profile identifies monoclonal mast cell disorders in patients with idiopathic anaphylaxis.

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    Midostaurin treatment in FLT3-mutated acute myeloid leukemia and systemic mastocytosis.

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    Multiple large osteolytic lesions in a patient with systemic mastocytosis: a challenging diagnosis.

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    Mast Cell Mediators of Significance in Clinical Practice in Mastocytosis.

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    Gastrointestinal Involvement in Mast Cell Activation Disorders.

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    c-KIT-Positive Fatal Diffuse Cutaneous Mastocytosis With Systemic Manifestations in a Neonate.

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    Midostaurin: A Multiple Tyrosine Kinases Inhibitor in Acute Myeloid Leukemia and Systemic Mastocytosis.

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    FDA Approval Summary: Midostaurin for the Treatment of Advanced Systemic Mastocytosis.

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    Aggressive systemic mastocytosis of the liver with cholangitis.

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    Smoldering mastocytosis: Survival comparisons with indolent and aggressive mastocytosis.

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    Systemic Mastocytosis, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology.

    Gotlib J, Gerds AT, Bose P, et al.

    Journal of the National Comprehensive Cancer Network : JNCCN 2018; (16(12)):1500-1537 doi:10.6004/jnccn.2018.0088.

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    [Surgical interventions in patients with systemic mast cell activation disease : Recommendations for perioperative management].

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    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 2019; (90(7)):548-556 doi:10.1007/s00104-019-0935-z.

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    Mast Cell Activation Syndrome and Mastocytosis: Initial Treatment Options and Long-Term Management.

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    The journal of allergy and clinical immunology. In practice 2019; (7(4)):1097-1106 doi:10.1016/j.jaip.2019.02.002.

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    Multidisciplinary Challenges in Mastocytosis and How to Address with Personalized Medicine Approaches.

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    International journal of molecular sciences 2019; (20(12)) doi:10.3390/ijms20122976.

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    Novel approaches to treating advanced systemic mastocytosis.

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    Clinical pharmacology : advances and applications 2019; (11()):77-92 doi:10.2147/CPAA.S206615.

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    Urticaria pigmentosa in monochorionic twins.

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    Efficacy of Omalizumab in Indolent Systemic Mastocytosis.

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    Evolution of myelodisplasic syndrome with ring sideroblasts (MDS-RS) to systemic mastocytosis and aleukemic mast cell leukemia.

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    KIT D816V and the cytokine storm in mastocytosis: production and role of interleukin-6.

    Valent P

    Haematologica 2020; (105(1)):5-6 doi:10.3324/haematol.2019.234864.

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    Systemic mastocytosis associated with Hodgkin's lymphoma in a 4-year-old child.

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    Mast Cell Activation Syndrome: A Primer for the Gastroenterologist.

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    Midostaurin improves quality of life and mediator-related symptoms in advanced systemic mastocytosis.

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    Systemic Mastocytosis: A Rare Cause of Diarrhea.

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    Cureus 2020; (12(7)):e9112 doi:10.7759/cureus.9112.

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    Heritable risk for severe anaphylaxis associated with increased α-tryptase-encoding germline copy number at TPSAB1.

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    Hereditary α tryptasemia is a valid genetic biomarker for severe mediator-related symptoms in mastocytosis.

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    Cutaneous mastocytosis: A dermatological perspective.

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    Pediatric maculopapular cutaneous mastocytosis: Retrospective review of signs, symptoms, and associated conditions.

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    Clinical Impact of Inherited and Acquired Genetic Variants in Mastocytosis.

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    Clinical Impact of Skin Lesions in Mastocytosis: A Multicenter Study of the European Competence Network on Mastocytosis.

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    Natural evolution in pediatric cutaneous mastocytosis: 10-year follow-up.

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    Medical algorithm: Peri-operative management of mastocytosis patients.

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    Health-Related Quality of Life and Influencing Factors in Adults with Nonadvanced Mastocytosis-A Cross-Sectional Study and Qualitative Approach.

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    Osteoporosis Caused by Systemic Mastocytosis: Prevalence in a Cohort of 8392 Patients with Osteoporosis.

    Gehlen M, Schmidt N, Pfeifer M, et al.

    Calcified tissue international 2021; (109(6)):685-695 doi:10.1007/s00223-021-00887-4.

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    Gastrointestinal Manifestations in Systemic Mastocytosis: The Need of a Multidisciplinary Approach.

    Zanelli M, Pizzi M, Sanguedolce F, et al.

    Cancers 2021; (13(13)) doi:10.3390/cancers13133316.

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    Refined diagnostic criteria for bone marrow mastocytosis: a proposal of the European competence network on mastocytosis.

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    Association of systemic mastocytosis with primary cutaneous marginal zone lymphoma; first case.

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    Pediatric Mastocytosis: An Update.

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    Safety and efficacy of avapritinib in advanced systemic mastocytosis: the phase 1 EXPLORER trial.

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    Updated Diagnostic Criteria and Classification of Mast Cell Disorders: A Consensus Proposal.

    Valent P, Akin C, Hartmann K, et al.

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    Cutaneous mastocytosis in childhood.

    Nemat K, Abraham S

    Allergologie select 2022; (6()):1-10 doi:10.5414/ALX02304E.

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    Indirect treatment comparisons of avapritinib versus midostaurin for patients with advanced systemic mastocytosis.

    Pilkington H, Smith S, Roskell N, Iannazzo S

    Future oncology (London, England) 2022; (18(13)):1583-1594 doi:10.2217/fon-2021-1509.

    PMID: 35114819
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    Role and significance of c-KIT receptor tyrosine kinase in cancer: A review.

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    Bosnian journal of basic medical sciences 2022; (22(5)):683-698 doi:10.17305/bjbms.2021.7399.

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    Treatment of Indolent and Advanced Systemic Mastocytosis.

    Buonomo A, Nucera E, Criscuolo M

    Mediterranean journal of hematology and infectious diseases 2022; (14(1)):e2022040 doi:10.4084/MJHID.2022.040.

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    Mast cell activation syndrome-anesthetic challenges in two different clinical scenarios.

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    Journal of biomedical research 2022; (36(6)):435-439 doi:10.7555/JBR.36.20220071.

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    Drugs and Vaccines Hypersensitivity in Children with Mastocytosis.

    Mori F, Crisafulli G, Bianchi A, et al.

    Journal of clinical medicine 2022; (11(11)) doi:10.3390/jcm11113153.

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    Target Therapies for Systemic Mastocytosis: An Update.

    Sciumè M, De Magistris C, Galli N, et al.

    Pharmaceuticals (Basel, Switzerland) 2022; (15(6)) doi:10.3390/ph15060738.

    PMID: 35745657
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    Immunohistochemical Staining to Identify Concomitant Systemic Mastocytosis in Acute Myeloid Leukemia with RUNX1::RUNX1T1.

    Hwang SM, Kim BJ, Lee JS, et al.

    Annals of laboratory medicine 2022; (42(6)):678-682 doi:10.3343/alm.2022.42.6.678.

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    Systemic Mastocytosis and Other Entities Involving Mast Cells: A Practical Review and Update.

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    Cancers 2022; (14(14)) doi:10.3390/cancers14143474.

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    Not quite "mast"ered: Patients and providers report limitations in the management of systemic mastocytosis.

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    Cancer 2022; (128(20)):3599-3601 doi:10.1002/cncr.34416.

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    Patient-reported outcomes among patients with systemic mastocytosis in routine clinical practice: Results of the TouchStone SM Patient Survey.

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    Cancer 2022; (128(20)):3691-3699 doi:10.1002/cncr.34420.

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    The international consensus classification of mastocytosis and related entities.

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    Virchows Archiv : an international journal of pathology 2023; (482(1)):99-112 doi:10.1007/s00428-022-03423-3.

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    Mastocytosis and related entities: a practical roadmap.

    Beyens M, Elst J, van der Poorten ML, et al.

    Acta clinica Belgica 2023; (78(4)):325-335 doi:10.1080/17843286.2022.2137631.

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    Disease correlates and clinical relevance of hereditary α-tryptasemia in patients with systemic mastocytosis.

    Sordi B, Vanderwert F, Crupi F, et al.

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    Successful treatment with Omalizumab of a child affected by Systemic Mastocytosis: clinical and biological implications.

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    Italian journal of pediatrics 2023; (49(1)):6 doi:10.1186/s13052-022-01402-7.

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    Comprehensive mastocytosis data analysis from a single center.

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    BMC cancer 2023; (23(1)):82 doi:10.1186/s12885-022-10498-3.

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    Delayed Diagnosis of Indolent Systemic Mastocytosis as the Cause of Unexplained Skin Rash: A Case Report.

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    Mast Cell Leukemia: An Update with a Practical Review.

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    Cancers 2023; (15(6)) doi:10.3390/cancers15061664.

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    Response and resistance to cladribine in patients with advanced systemic mastocytosis: a registry-based analysis.

    Lübke J, Naumann N, Metzgeroth G, et al.

    Annals of hematology 2023; (102(8)):2077-2085 doi:10.1007/s00277-023-05180-y.

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    Hereditary alpha-tryptasemia and complete deletion of exon 8 of the c-kit gene in patients with mast cell activation syndrome.

    Jiang M, Vadas P

    Leukemia & lymphoma 2023; (64(7)):1348-1351 doi:10.1080/10428194.2023.2203286.

    PMID: 37086476
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    Childhood Cutaneous Mastocytosis: Revisited.

    Swarnkar B, Sarkar R

    Indian journal of dermatology 2023; (68(1)):121 doi:10.4103/ijd.ijd_264_22.

    PMID: 37151240
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    Skin and bones: systemic mastocytosis and bone.

    Wang M, Seibel MJ

    Endocrinology, diabetes & metabolism case reports 2023; (2023(2)).

    PMID: 37166908
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    Indolent systemic mastocytosis and aleukemic mast cell leukemia: Subtle diagnostic differences with distinct management approaches.

    Paiva ML, Yumeen S, Saliba E, DiMarco C

    JAAD case reports 2023; (36()):63-66 doi:10.1016/j.jdcr.2023.04.009.

    PMID: 37250010
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    The international consensus classification of eosinophilic disorders and systemic mastocytosis.

    Wang SA, Orazi A, Gotlib J, et al.

    American journal of hematology 2023; (98(8)):1286-1306 doi:10.1002/ajh.26966.

    PMID: 37283522
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    c-Kit signaling potentiates CAR T cell efficacy in solid tumors by CD28- and IL-2-independent co-stimulation.

    Xiong Y, Taleb M, Misawa K, et al.

    Nature cancer 2023; (4(7)):1001-1015 doi:10.1038/s43018-023-00573-4.

    PMID: 37336986
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    Increased TIM-3 and galectin-9 serum levels in patients with advanced systemic mastocytosis.

    Konantz M, Williams M, Merkel T, et al.

    The Journal of allergy and clinical immunology 2023; (152(4)):1019-1024 doi:10.1016/j.jaci.2023.07.001.

    PMID: 37423405
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    KIT Mutations and Other Genetic Defects in Mastocytosis: Implications for Disease Pathology and Targeted Therapies.

    Chantran Y, Valent P, Arock M

    Immunology and allergy clinics of North America 2023; (43(4)):651-664 doi:10.1016/j.iac.2023.04.008.

    PMID: 37758404
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    Gastrointestinal Disease in Mastocytosis.

    Hamilton MJ

    Immunology and allergy clinics of North America 2023; (43(4)):711-722 doi:10.1016/j.iac.2023.04.005.

    PMID: 37758408
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    Management of Advanced Systemic Mastocytosis and Associated Myeloid Neoplasms.

    Tashi T, Deininger MW

    Immunology and allergy clinics of North America 2023; (43(4)):723-741 doi:10.1016/j.iac.2023.04.009.

    PMID: 37758409
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    Granularity in disease classification impacts survival prediction in advanced systemic mastocytosis: A single institution study of 329 informative cases.

    Tefferi A, Abdelmagid M, Al-Kali A, et al.

    American journal of hematology 2024; (99(1)):21-27 doi:10.1002/ajh.27113.

    PMID: 37772442
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    Clinical impact of the TPSAB1 genotype in mast cell diseases: A REMA study in a cohort of 959 individuals.

    González-de-Olano D, Navarro-Navarro P, Muñoz-González JI, et al.

    Allergy 2024; (79(3)):711-723 doi:10.1111/all.15911.

    PMID: 37818990
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    Current Challenges in the Diagnosis of Pediatric Cutaneous Mastocytosis.

    Ługowska-Umer H, Czarny J, Rydz A, et al.

    Diagnostics (Basel, Switzerland) 2023; (13(23)) doi:10.3390/diagnostics13233583.

    PMID: 38066824
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    Review and Updates on Systemic Mastocytosis and Related Entities.

    Li JY, Ryder CB, Zhang H, et al.

    Cancers 2023; (15(23)) doi:10.3390/cancers15235626.

    PMID: 38067330
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    Epidemiology of mastocytosis: a population-based study (Sweden).

    Bergström A, Hägglund H, Berglund A, et al.

    Acta oncologica (Stockholm, Sweden) 2024; (63()):44-50 doi:10.2340/1651-226X.2024.31406.

    PMID: 38380845
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    Prevalence of hypersensitivity reactions in various forms of mastocytosis: A pilot study of 2485 adult patients with mastocytosis collected in the ECNM registry.

    Niedoszytko M, Gorska A, Brockow K, et al.

    Allergy 2024; (79(9)):2470-2481 doi:10.1111/all.16132.

    PMID: 38651829
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    NCCN Guidelines® Insights: Systemic Mastocytosis, Version 3.2024.

    Gotlib J, Gerds AT, Abdelmessieh P, et al.

    Journal of the National Comprehensive Cancer Network : JNCCN 2024; (22(2 D)).

    PMID: 38862005
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    Beyond Midostaurin: Role of Avapritinib in Managing Systemic Mastocytosis.

    Pokima N, Khattar G, Keesari PR, et al.

    Cureus 2024; (16(5)):e60161 doi:10.7759/cureus.60161.

    PMID: 38868249
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    Indolent systemic mastocytosis (ISM) without skin lesions as a recurrent anaphylaxis: a case report study.

    Ghelichi-Ghojogh M, Ebrahimi M, Ghezeljeh E, et al.

    Annals of medicine and surgery (2012) 2024; (86(10)):6179-6181 doi:10.1097/MS9.0000000000002472.

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    Prevalence and incidence of mastocytosis in adults: a Danish nationwide register study.

    Jørgensen MP, Øvlisen AK, Jensen JF, et al.

    European journal of epidemiology 2025; (40(1)):43-53 doi:10.1007/s10654-024-01195-5.

    PMID: 39751701
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