Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
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Baylor College of Medicine
Houston, United States
Texas Children's Hospital
Houston, United States
Children's Hospital of Philadelphia
Philadelphia, United States
University of Alabama at Birmingham
Birmingham, United States
University of Zurich
Zurich, Switzerland
Boston Children's Hospital
Boston, United States
Riley Hospital for Children
Indianapolis, United States
University of California, San Francisco
San Francisco, United States
Cincinnati Children's Hospital Medical Center
Cincinnati, United States
Centers for Disease Control and Prevention
Atlanta, United States
References
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Prenatal surgery for myelomeningocele: review of the literature and future directions.
Heuer GG, Moldenhauer JS, Scott Adzick N
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2017; (33(7)):1149-1155 doi:10.1007/s00381-017-3440-z.
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Team Approach: Guideline-Based Management of Skin Injury in Individuals with Myelomeningocele.
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Subsequent pregnancy outcomes after open maternal-fetal surgery for myelomeningocele.
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American journal of obstetrics and gynecology 2019; (220(5)):494.e1-494.e7 doi:10.1016/j.ajog.2019.03.008.
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Association of maternal risk factors with the recent rise of neural tube defects in Canada.
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Correlation Between Neurologic Impairment Grade and Ambulation Status in the Adult Spina Bifida Population.
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The Use of Indomethacin with Complete Amniotic Fluid Replacement and Classic Hysterotomy for the Reduction of Perinatal Complications of Intrauterine Myelomeningocele Repair.
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Benchmarking against the MOMS Trial: Zurich Results of Open Fetal Surgery for Spina Bifida.
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Detailed Analysis of Hydrocephalus and Hindbrain Herniation After Prenatal and Postnatal Myelomeningocele Closure: Report From a Single Institution.
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A case report of triple neural tube defect: revisiting the multisite closure theory.
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The reliability and validity of a newly developed spina bifida-specific Transition Readiness Assessment Questionnaire: Transition Readiness Assessment Questionnaire-supplement (TRAQ-SB).
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Journal of pediatric rehabilitation medicine 2019; (12(4)):415-422 doi:10.3233/PRM-180599.
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Surgical outcomes of six bulldogs with spinal lumbosacral meningomyelocele or meningocele.
Martín Muñiz L, Del Magno S, Gandini G, et al.
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Continent Cutaneous Catheterizable Channels in Pediatric Patients: A Decade of Experience with Open and Robotic Approaches in a Single Center.
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Determination of Anatomical Levels in Spina Bifida Fetuses with Ultrasound and MRI.
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Prenatal diagnosis of frontal encephalocele.
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Systematic classification of maternal and fetal intervention-related complications following open fetal myelomeningocele repair - results from a large prospective cohort.
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Guideline No. 410: Prevention, Screening, Diagnosis, and Pregnancy Management for Fetal Neural Tube Defects.
Douglas Wilson R, Van Mieghem T, Langlois S, Church P
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Latex allergy guidelines for people with spina bifida.
Meneses V, Parenti S, Burns H, Adams R
Journal of pediatric rehabilitation medicine 2020; (13(4)):601-609 doi:10.3233/PRM-200741.
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Hallmarks of primary neurulation are conserved in the zebrafish forebrain.
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Communications biology 2021; (4(1)):147 doi:10.1038/s42003-021-01655-8.
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Seeking tirelessly for better health and life conditions for the child with myelomeningocele.
Bonelli MA, Borges AA, Souza ROD, et al.
Revista latino-americana de enfermagem 2021; (29()):e3428 doi:10.1590/1518-8345.3957.3428.
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Arnold-Chiari Malformation: Core Concepts.
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Neonatal network : NN 2021; (40(5)):313-320 doi:10.1891/11-T-704.
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Influence in the outcome of neuropathic pediatric patients after early treatment.
Burgos Lucena L, López Pereira P, Martínez Urrutia MJ, et al.
Actas urologicas espanolas 2021; doi:10.1016/j.acuro.2021.01.005.
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Cerebral Abnormalities in Spina Bifida: A Neuropathological Study.
Paschereit F, Schindelmann KH, Hummel M, et al.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 2022; (25(2)):107-123 doi:10.1177/10935266211040500.
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A silent epidemic of major congenital malformations in Tigray, northern Ethiopia: hospital-based study.
Mekonen HK, Berhe Y, Berihu BA, et al.
Scientific reports 2021; (11(1)):21035 doi:10.1038/s41598-021-00240-7.
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Influence in the outcome of neuropathic pediatric patients after early treatment.
Burgos Lucena L, López Pereira P, Martínez Urrutia MJ, et al.
Actas urologicas espanolas 2022; (46(1)):28-34 doi:10.1016/j.acuroe.2021.01.012.
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Early prenatal diagnosis of an atypical phenotype of sacral spina bifida.
Bohîlțea RE, Margareta Mihai B, Munteanu O, et al.
Journal of medicine and life 2021; (14(5)):716-721 doi:10.25122/jml-2021-0292.
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Hydrocephalus in Spina Bifida.
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Neurology India 2021; (69(Supplement)):S367-S371 doi:10.4103/0028-3886.332247.
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Prevalence of neural tube defects at Debre Berhan Referral Hospital, North Shewa, Ethiopia. A hospital based retrospective cross-section study.
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PloS one 2022; (17(2)):e0261177 doi:10.1371/journal.pone.0261177.
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Determination of anatomic level of myelomeningocele by prenatal ultrasound.
Barnes KS, Singh S, Barkley A, et al.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2022; (38(5)):985-990 doi:10.1007/s00381-022-05469-9.
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Factors Associated With Neural Tube Defects Among Newborns Delivered at Debre Berhan Specialized Hospital, North Eastern Ethiopia, 2021. Case-Control Study.
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Usefulness of videourodynamic study in the decision-making of surgical intervention and bladder management for neurogenic lower urinary tract dysfunction among patients with myelomeningocele.
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International urology and nephrology 2022; (54(8)):1815-1824 doi:10.1007/s11255-022-03236-y.
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Ultrasound evaluation of uterine scar thickness after open fetal surgery for myelomeningocele.
Sasaoka AKS, Moron AF, Araujo Júnior E, et al.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2023; (39(3)):655-661 doi:10.1007/s00381-022-05642-0.
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Fetal magnetic resonance imaging in the diagnosis of spinal cord neural tube defects: A prospective study.
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AbobotulinumtoxinA is effective in patients with urinary incontinence due to neurogenic detrusor overactivity regardless of spinal cord injury or multiple sclerosis etiology: Pooled analysis of two phase III randomized studies (CONTENT1 and CONTENT2).
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Neurourology and urodynamics 2023; (42(1)):153-167 doi:10.1002/nau.25062.
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Fetal Repair of Neural Tube Defects.
Lee SY, Papanna R, Farmer D, Tsao K
Clinics in perinatology 2022; (49(4)):835-848 doi:10.1016/j.clp.2022.06.004.
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Open and endoscopic fetal myelomeningocele surgeries display similar in-hospital safety profiles in a large, multi-institutional database.
Mikulski MF, Well A, Beckerman Z, et al.
American journal of obstetrics & gynecology MFM 2023; (5(3)):100854 doi:10.1016/j.ajogmf.2022.100854.
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Neurologic Outcome Comparison between Fetal Open-, Endoscopic- and Neonatal-Intervention Techniques in Spina Bifida Aperta.
Sival DA, Patuszka A, Koszutski T, et al.
Diagnostics (Basel, Switzerland) 2023; (13(2)) doi:10.3390/diagnostics13020251.
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Global strategies for the prevention of neural tube defects through the improvement of folate status in women of reproductive age.
Martinez H, Benavides-Lara A, Arynchyna-Smith A, et al.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2023; (39(7)):1719-1736 doi:10.1007/s00381-023-05913-4.
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Outcomes of autologous bone marrow mononuclear cell administration in the treatment of neurologic sequelae in children with spina bifida.
Nguyen LT, Le HT, Nguyen KT, et al.
Stem cell research & therapy 2023; (14(1)):115 doi:10.1186/s13287-023-03349-w.
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Administration of prosaposin-derived neurotrophic factor to neural tube defects facilitates regeneration and restores neurological functions.
Khan S, Takeuchi A, Nabeka H, et al.
iScience 2023; (26(4)):106277 doi:10.1016/j.isci.2023.106277.
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What has changed in pediatric neurosurgical care in spina bifida? A 30-year UAB/Children's of Alabama observational overview.
Blount JP, Hopson BD, Johnston JM, et al.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2023; (39(7)):1791-1804 doi:10.1007/s00381-023-05938-9.
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Multidisciplinary management of people with spina bifida across the lifespan.
Koch VH, Lopes M, Furusawa E, et al.
Pediatric nephrology (Berlin, Germany) 2024; (39(3)):681-697 doi:10.1007/s00467-023-06067-w.
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Motor function outcomes in children with open prenatal repair of Spina Bifida Aperta at 36-month follow-up: The Zurich cohort.
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Journal of pediatric rehabilitation medicine 2023; (16(4)):595-604 doi:10.3233/PRM-220096.
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2023 updates to the spina bifida transition to adult care guidelines.
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Journal of pediatric rehabilitation medicine 2023; (16(4)):583-593 doi:10.3233/PRM-230052.
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Spina Bifida Prevention: A Narrative Review of Folic Acid Supplements for Childbearing Age Women.
Ledet Iii LF, Plaisance CJ, Daniel CP, et al.
Cureus 2024; (16(1)):e53008 doi:10.7759/cureus.53008.
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Patterns and short term neurosurgical treatment outcomes of neonates with neural tube defects admitted to Felege Hiwot Specialized Hospital, Bahir Dar, Ethiopia.
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BMC pediatrics 2024; (24(1)):350 doi:10.1186/s12887-024-04837-5.
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Imaging Fetal Spine Malformations in the Context of In Utero Surgery.
Nagaraj UD, Bierbrauer KS, Stevenson CB
Magnetic resonance imaging clinics of North America 2024; (32(3)):431-442 doi:10.1016/j.mric.2024.01.004.
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Out-of-pocket and indirect expenditure of spina bifida and hydrocephalus patients admitted for inpatient treatment and follow-up at two university-affiliated hospitals in Ethiopia.
Yesehak B, Zewdie K, Bizuneh Y, et al.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2024; (40(12)):4137-4144 doi:10.1007/s00381-024-06647-7.
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Togaram1 is expressed in the neural tube and its absence causes neural tube closure defects.
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HGG advances 2025; (6(1)):100363 doi:10.1016/j.xhgg.2024.100363.
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The contribution of de novo coding mutations to meningomyelocele.
Ha YJ, Nisal A, Tang I, et al.
Nature 2025; (641(8062)):419-426 doi:10.1038/s41586-025-08676-x.
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Changes and Needs Experienced by People Aging With Spina Bifida and Hydrocephalus.
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The Gerontologist 2025; (65(6)) doi:10.1093/geront/gnaf101.
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Safety and Effectiveness of Fetal Myelomeningocele Repair: Case Series Analysis Using an Exteriorized Uterus and a Fetoscopic Approach.
Miranda ML, Ximenes R, Andrade KC, et al.
Fetal diagnosis and therapy 2025; (52(5)):521-531 doi:10.1159/000546549.
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Risk factors for neural tube defects in the war and siege-affected tigray regional state of ethiopia: a case-control study.
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BMC pregnancy and childbirth 2025; (25(1)):638 doi:10.1186/s12884-025-07724-8.
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Evaluating Decisional Regret in Adults With Spina Bifida Regarding Childhood Surgeries for Neurogenic Bladder and Bowel.
Batra NV, Johnston AW, Cain MP, et al.
The Journal of urology 2025; (214(4)):426-434 doi:10.1097/JU.0000000000004643.
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Perinatal palliative care in an infant with exencephaly: Supporting life beyond 3 years of age.
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