Research & Literature

Lipodermatosclerosis: a clinicopathologic correlation.

Choonhakarn C, Chaowattanapanit S, Julanon N

International journal of dermatology 2016; (55(3)):303-8 doi:10.1111/ijd.12856.

Prevalence of Venous Thrombosis Following Venovenous Extracorporeal Membrane Oxygenation in Patients With Severe Respiratory Failure.

Cooper E, Burns J, Retter A, et al.

Critical care medicine 2015; (43(12)):e581-4 doi:10.1097/CCM.0000000000001277.

Stewart Treves Syndrome.

Pereira ES, Moraes ET, Siqueira DM, Santos MA

Anais brasileiros de dermatologia 2015; (90(3 Suppl 1)):229-31.

Indocyanine Green Lymphography Findings in Limb Lymphedema.

Narushima M, Yamamoto T, Ogata F, et al.

Journal of reconstructive microsurgery 2016; (32(1)):72-9 doi:10.1055/s-0035-1564608.

Erysipelas, a large retrospective study of aetiology and clinical presentation.

Bläckberg A, Trell K, Rasmussen M

BMC infectious diseases 2015; (15()):402 doi:10.1186/s12879-015-1134-2.

A Detailed Examination of the Characteristics and Treatment in a Series of 33 Idiopathic Lymphedema Patients.

Onoda S, Yamada K, Matsumoto K, Kimata Y

Journal of reconstructive microsurgery 2017; (33(1)):19-25 doi:10.1055/s-0036-1586257.

Beckwith-Wiedemann Syndrome and Primary Lymphedema of the Lower Extremity.

Beijnen UE, Maclellan RA, Goss JA, et al.

Pediatric dermatology 2017; (34(1)):e51-e53 doi:10.1111/pde.13017.

Pitfall of modern genetics: recurrent erysipelas masquerading as autoinflammatory disease.

Spierings EJW, van der Meer JWM, Simon A

The Netherlands journal of medicine 2017; (75(6)):247-249.

[Primary congenital lymphedema: Milroy disease: the first case observed in the Department of Pediatrics at the University Hospital Yalgado Ouedraogo, Ouagadougou].

Ouattara CZ, Kalmogho A, Yonaba C, et al.

The Pan African medical journal 2017; (27()):21 doi:10.11604/pamj.2017.27.21.11443.

Stewart-Treves syndrome: Magnetic resonance imaging data compared with pathological results from a single center.

Li B, Wang Z

Oncology letters 2018; (15(1)):1113-1118 doi:10.3892/ol.2017.7363.

Nonoperative Treatment of Lymphedema.

Schaverien MV, Moeller JA, Cleveland SD

Seminars in plastic surgery 2018; (32(1)):17-21 doi:10.1055/s-0038-1635119.

Mobilization of Fluids in the Intensive Treatment of Primary and Secondary Lymphedemas.

de Godoy JMP, Pereira de Godoy HJ, Gracino de Marqui T, et al.

TheScientificWorldJournal 2018; (2018()):6537253 doi:10.1155/2018/6537253.

Validity of the Novel Taiwan Lymphoscintigraphy Staging and Correlation of Cheng Lymphedema Grading for Unilateral Extremity Lymphedema.

Cheng MH, Pappalardo M, Lin C, et al.

Annals of surgery 2018; (268(3)):513-525 doi:10.1097/SLA.0000000000002917.

Cryogenic Numbing to Reduce Injection Discomfort during Indocyanine Green Lymphography.

Suami H, Heydon-White A, Mackie H, et al.

Journal of reconstructive microsurgery 2019; (35(2)):e1-e2 doi:10.1055/s-0038-1667362.

A LYVE-1/CRSBP-1 Mutation in Inherited Primary Lymphedema.

Liu NF, Yu Z, Luo Y, Sun D

Lymphology 2017; (50(1)):9-15.

Unilateral Primary Congenital Lymphedema of the Upper Limb in an 11-Month-Old Infant: A Clinical and Pharmacological Perspective.

Meshram GG, Kaur N, Hura KS

Open access Macedonian journal of medical sciences 2018; (6(9)):1682-1684 doi:10.3889/oamjms.2018.261.

Outcomes of Vascularized Lymph Node Transfer and Lymphovenous Anastomosis for Treatment of Primary Lymphedema.

Cheng MH, Loh CYY, Lin CY

Plastic and reconstructive surgery. Global open 2018; (6(12)):e2056 doi:10.1097/GOX.0000000000002056.

Cutaneous Angiosarcoma Secondary to Lymphoedema or Radiation Therapy - A Systematic Review.

Co M, Lee A, Kwong A

Clinical oncology (Royal College of Radiologists (Great Britain)) 2019; (31(4)):225-231 doi:10.1016/j.clon.2019.01.009.

Adult-Onset Primary Lymphedema: A Clinical-Lymphoscintigraphic Study of 26 Patients.

Goss JA, Maclellan RA, Greene AK

Lymphatic research and biology 2019; (17(6)):620-623 doi:10.1089/lrb.2018.0032.

Frequent colonization of betahaemolytic streptococci at various body sites including the perineum and anal canal during erysipelas and cellulitis.

Eriksson BKG, Karkkonen K, Jorup-Rönström C, Wretlind B

Infectious diseases (London, England) 2019; (51(7)):534-540 doi:10.1080/23744235.2019.1606934.

Guillain-Barré syndrome in a cancer patient treated with bevacizumab.

Taguchi D, Kamada S, Yoshida T, et al.

International cancer conference journal 2018; (7(3)):87-92 doi:10.1007/s13691-018-0326-1.

Surgical treatment of Milroy disease.

Bolletta A, Di Taranto G, Chen SH, et al.

Journal of surgical oncology 2020; (121(1)):175-181 doi:10.1002/jso.25583.

The diagnostic unreliability of classic physical signs of lymphedema.

Jayaraj A, Raju S, May C, Pace N

Journal of vascular surgery. Venous and lymphatic disorders 2019; (7(6)):890-897 doi:10.1016/j.jvsv.2019.04.013.

Real-time Indocyanine Green Videolymphography Navigation for Lymphaticovenular Anastomosis.

Seki Y, Kajikawa A, Yamamoto T, et al.

Plastic and reconstructive surgery. Global open 2019; (7(5)):e2253 doi:10.1097/GOX.0000000000002253.

Sensitivity and Specificity of the Stemmer Sign for Lymphedema: A Clinical Lymphoscintigraphic Study.

Goss JA, Greene AK

Plastic and reconstructive surgery. Global open 2019; (7(6)):e2295 doi:10.1097/GOX.0000000000002295.

Resource overutilization in the diagnosis of lymphedema praecox.

Shah AA, Petrosyan M, Nizam W, et al.

Journal of pediatric surgery 2020; (55(7)):1363-1365 doi:10.1016/j.jpedsurg.2019.09.014.

Lymphoscintigraphic Abnormalities Associated with Milroy Disease and Lymphedema-Distichiasis Syndrome.

Sarica M, Gordon K, van Zanten M, et al.

Lymphatic research and biology 2019; (17(6)):610-619 doi:10.1089/lrb.2019.0016.

Update and audit of the St George's classification algorithm of primary lymphatic anomalies: a clinical and molecular approach to diagnosis.

Gordon K, Varney R, Keeley V, et al.

Journal of medical genetics 2020; (57(10)):653-659 doi:10.1136/jmedgenet-2019-106084.

Congenital lymphedema as a rare and first symptom of tuberous sclerosis complex.

Klinner J, Krüger M, Brunet T, et al.

Gene 2020; (753()):144815 doi:10.1016/j.gene.2020.144815.

Increased levels of VEGF-C and macrophage infiltration in lipedema patients without changes in lymphatic vascular morphology.

Felmerer G, Stylianaki A, Hollmén M, et al.

Scientific reports 2020; (10(1)):10947 doi:10.1038/s41598-020-67987-3.

The results of the intensive phase of complete decongestive therapy and the determination of predictive factors for response to treatment in patients with breast cancer related-lymphedema.

Keskin D, Dalyan M, Ünsal-Delialioğlu S, Düzlü-Öztürk Ü

Cancer reports (Hoboken, N.J.) 2020; (3(2)):e1225 doi:10.1002/cnr2.1225.

Characterization of ANGPT2 mutations associated with primary lymphedema.

Leppänen VM, Brouillard P, Korhonen EA, et al.

Science translational medicine 2020; (12(560)) doi:10.1126/scitranslmed.aax8013.

Clinical aspects of congenital primary lymphedema.

de Godoy ACP, de Godoy LMP, de Godoy JMP, de Fatima Guerreiro Godoy M

Journal of pediatric rehabilitation medicine 2021; (14(1)):51-53 doi:10.3233/PRM-190642.

The St George's Classification Algorithm of Primary Lymphatic Anomalies.

Gordon K, Mortimer PS, van Zanten M, et al.

Lymphatic research and biology 2021; (19(1)):25-30 doi:10.1089/lrb.2020.0104.

Primary lymphedema French National Diagnosis and Care Protocol (PNDS; Protocole National de Diagnostic et de Soins).

Vignes S, Albuisson J, Champion L, et al.

Orphanet journal of rare diseases 2021; (16(1)):18 doi:10.1186/s13023-020-01652-w.

Rest/stress intradermal lymphoscintigraphy in diagnosis of lipedema.

Tartaglione G, Visconti G, Bartoletti R, et al.

World journal of nuclear medicine 2020; (19(4)):376-381 doi:10.4103/wjnm.WJNM_5_20.

Stewart-Treves Syndrome as a Rare and Fatal Complication of Post-Traumatic Lymphedema on the Lower Extremity.

Leite LL, Rossato V

Dermatology practical & conceptual 2021; (11(2)):e2021004 doi:10.5826/dpc.1102a04.

Lymphedema complicated by protein-losing enteropathy with a 22q13.3 deletion and the potential role of CELSR1: A case report.

Xia S, Liu Z, Yan H, et al.

Medicine 2021; (100(24)):e26307 doi:10.1097/MD.0000000000026307.

Efficacy of Microsurgical Treatment of Primary Lymphedema: A Systematic Review.

Fallahian F, Tadisina KK, Xu KY

Annals of plastic surgery 2022; (88(2)):195-199 doi:10.1097/SAP.0000000000002862.

Combined Complete Decongestive Therapy Reduces Volume and Improves Quality of Life and Functional Status in Patients With Breast Cancer-Related Lymphedema.

Borman P, Yaman A, Yasrebi S, et al.

Clinical breast cancer 2022; (22(3)):e270-e277 doi:10.1016/j.clbc.2021.08.005.

Association of Dermal Hypoechogenicity and Cellulitis History in Patients with Lower Extremity Lymphedema: A Cross-Sectional Observational Study.

Dai M, Minematsu T, Ogawa Y, et al.

Lymphatic research and biology 2022; (20(4)):376-381 doi:10.1089/lrb.2021.0004.

Lymphedema and Obesity.

Sudduth CL, Greene AK

Cold Spring Harbor perspectives in medicine 2022; (12(5)) doi:10.1101/cshperspect.a041176.

Microdeletion of 16q24.1-q24.2-A unique etiology of Lymphedema-Distichiasis syndrome and neurodevelopmental disorder.

Michelson M, Lidzbarsky G, Nishri D, et al.

American journal of medical genetics. Part A 2022; (188(7)):1990-1996 doi:10.1002/ajmg.a.62730.

Chronic venous insufficiency: a comprehensive review of management.

Azar J, Rao A, Oropallo A

Journal of wound care 2022; (31(6)):510-519 doi:10.12968/jowc.2022.31.6.510.

Synthesis and Physiological Remodeling of CD34 Cells in the Skin following the Reversal of Fibrosis through Intensive Treatment for Lower Limb Lymphedema: A Case Report.

Pereira de Godoy JM, Pereira de Godoy AC, Guerreiro Godoy MF, de Santi Neto D

Dermatopathology (Basel, Switzerland) 2023; (10(1)):104-111 doi:10.3390/dermatopathology10010016.

Current Concepts in the Management of Primary Lymphedema.

Senger JB, Kadle RL, Skoracki RJ

Medicina (Kaunas, Lithuania) 2023; (59(5)) doi:10.3390/medicina59050894.

[Lymphangioma of the scrotum].

Safin DA, Tarusin DI, Matar AA

Urologiia (Moscow, Russia : 1999) 2023; 107-110.

Lymphatic Vascular Insufficiency and Focal Edema in Early Stages of Noncancer-Related Lymphedema.

Zaleska MT, Krzesniak NE

Lymphatic research and biology 2023; (21(6)):585-593 doi:10.1089/lrb.2023.0008.

Pigmentation of lower limbs: Contribution of haemosiderin and melanin in chronic venous insufficiency and related disorders.

Zhang L, Ng K, Pham JP, et al.

Phlebology 2023; (38(10)):657-667 doi:10.1177/02683555231196702.

Intramuscular epidermal cyst in the masticator space: a case report.

Han SW, Kim J, Kim SW, et al.

Archives of craniofacial surgery 2023; (24(4)):193-197 doi:10.7181/acfs.2023.00136.

Lymphoscintigraphy Findings are Associated with Outcome in Children with Chylothorax After Cardiac Surgery.

Suzuki S, Kodama Y, Kuraoka A, et al.

Pediatric cardiology 2024; (45(1)):150-155 doi:10.1007/s00246-023-03303-w.

The clinical and economic impact of chronic venous insufficiency-associated lymphedema and the prevalence of persistent edema after venous intervention.

Genet M, Labropoulos N, Gasparis A, et al.

Phlebology 2024; (39(5)):353-358 doi:10.1177/02683555241233355.

Managing lymphoedema following treatment for head and neck cancer: is complete decongestive therapy an effective intervention to improve dysphagia outcomes?

Smith A

Current opinion in otolaryngology & head and neck surgery 2024; (32(3)):178-185 doi:10.1097/MOO.0000000000000969.

Effectiveness of lymphaticovenular anastomosis for adult-onset primary lower limb lymphedema: A retrospective study.

Kumegawa S, Sakata Y, Fujimoto K, et al.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS 2024; (91()):191-199 doi:10.1016/j.bjps.2024.01.008.

Genetic causes of lymphatic disorders: recent updates on the clinical and molecular aspects of lymphatic disease.

Bowman C, Rockson SG

Current opinion in cardiology 2024; (39(3)):170-177 doi:10.1097/HCO.0000000000001116.

Comparison of fluid and body composition measures in women with lipoedema, lymphoedema, and control participants.

Stellmaker R, Thompson B, Mackie H, Koelmeyer L

Clinical obesity 2024; (14(4)):e12658 doi:10.1111/cob.12658.

Surgical Treatment for Primary Lymphedema: A Systematic Review of the Literature.

Gaxiola-García MA, Escandón JM, Manrique OJ, et al.

Archives of plastic surgery 2024; (51(2)):212-233 doi:10.1055/a-2253-9859.

Primary LYmphedema Multidisciplinary Approach in Patients Affected by Primary Lower Extremity Lymphedema.

Ciudad P, Bolletta A, Kaciulyte J, et al.

Journal of clinical medicine 2024; (13(17)) doi:10.3390/jcm13175161.

Multi-Stage Surgical Debulking for Advanced Lower Limb Lymphedema: Achieving Cosmetic and Functional Success.

Bani Monia OG, AlSaket GI, AlKadhimi AM, et al.

Cureus 2024; (16(11)):e73053 doi:10.7759/cureus.73053.

Identification of a Novel FLT4 c.3028A>C Variant Associated With Milroy Disease.

Feiskhanov A, Ibragimova A, Gaysina E, et al.

Clinical genetics 2025; (107(5)):541-546 doi:10.1111/cge.14671.

Primary Lymphedema: Anatomically Isolated or a Pervasive Systemic Disorder?

Chen WF, Jou C, Pandey SK, Lo SL

Plastic and reconstructive surgery. Global open 2024; (12(12)):e6328 doi:10.1097/GOX.0000000000006328.

18F-FDG PET/CT in lymphangiosarcoma: A case report and review of literature.

Gupta N

Asia Oceania journal of nuclear medicine & biology 2025; (13(1)):107-113 doi:10.22038/aojnmb.2024.77689.1548.

Effective Management Strategies for Primary Lymphedema of the Lower Extremities: Integrating Conservative and Surgical Therapies in Early and Late Stages.

Farid Y, Pozzi M, Bolletta A, et al.

Microsurgery 2025; (45(1)):e70014 doi:10.1002/micr.70014.

Advanced Doppler Ultrasound Insights: A Multicenter Prospective Study on Healthy Skin.

Giavedoni P, Romaní J, de Cabo F, et al.

Diagnostics (Basel, Switzerland) 2025; (15(5)) doi:10.3390/diagnostics15050569.

Single modality indocyanine green is feasible for sentinel node detection in head and neck cutaneous melanoma: A prospective cohort study.

Vyas R, Jones C, Machin AH

Journal of plastic, reconstructive & aesthetic surgery : JPRAS 2025; (106()):19-26 doi:10.1016/j.bjps.2025.05.002.

Prevalence of Pre-Existing Subclinical Leg Lymphedema in Patients with Erysipelas.

Merzel Šabović EK, Planinšek Ručigaj T

Journal of cutaneous medicine and surgery 2025; (29(3)):263-267 doi:10.1177/12034754241308239.

Nuclear Medicine Lymphoscintigraphy: Applications and Technical Overview.

Basavalingu D, Elojeimy S, Mercer MK, et al.

Radiographics : a review publication of the Radiological Society of North America, Inc 2025; (45(7)):e240207 doi:10.1148/rg.240207.

Factors associated with lymphedema volume in patients with unilateral lower extremity lymphedema.

Ergin G, Şahinoğlu E, Karadibak D

Phlebology 2026; (41(3)):254-260 doi:10.1177/02683555251357141.

Epidemiology of erysipelas and necrotising soft tissue infections.

Tang AHR, Lassen AT, Skjøt-Arkil H, et al.

Danish medical journal 2025; (72(9)) doi:10.61409/A02250077.

Cancer related lymphedema.

Cheville AL, McLaughlin SA, Glaser GE, Boughey JC

BMJ (Clinical research ed.) 2025; (390()) doi:10.1136/bmj-2024-081351.

Lymphedema Imaging and AI: A Review of Diagnostic Modalities, Biomarkers, and Clinical Integration.

Urooj B, Ali S, Naqvi SKH, et al.

Biomedical journal 2025; 100932 doi:10.1016/j.bj.2025.100932.

Elephantiasis Nostra Verrucosa Complicated by Cellulitis and Hemorrhagic Bullae: A Rare and Severe Clinical Presentation.

Nadeem A, Choudhry I

Cureus 2026; (18(1)):e102148 doi:10.7759/cureus.102148.