Research & Literature
Explore the leading researchers and institutions driving advances in this area, and dive into the full body of literature that informs this resource.
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Broad Institute
Cambridge, United States
Harvard University
Cambridge, United States
Brigham and Women's Hospital
Boston, United States
Cornell University
Ithaca, United States
Tzu Chi University
Hualien City, Taiwan
Emory University
Atlanta, United States
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Pittsburgh, United States
Boston Children's Hospital
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Los Angeles, United States
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References
References (59)
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MRI suggests increased tonicity of the levator ani in women with interstitial cystitis/bladder pain syndrome.
Ackerman AL, Lee UJ, Jellison FC, et al.
International urogynecology journal 2016; (27(1)):77-83 doi:10.1007/s00192-015-2794-6.
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Tanezumab Reduces Pain in Women with Interstitial Cystitis/Bladder Pain Syndrome and Patients with Nonurological Associated Somatic Syndromes.
Nickel JC, Mills IW, Crook TJ, et al.
The Journal of urology 2016; (195(4 Pt 1)):942-8.
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Use of Botulinum Toxin in Urologic Diseases.
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The enigma of men with interstitial cystitis/bladder pain syndrome.
Arora HC, Shoskes DA
Translational andrology and urology 2015; (4(6)):668-76 doi:10.3978/j.issn.2223-4683.2015.10.01.
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Similarities between interstitial cystitis/bladder pain syndrome and vulvodynia: implications for patient management.
Fariello JY, Moldwin RM
Translational andrology and urology 2015; (4(6)):643-52 doi:10.3978/j.issn.2223-4683.2015.10.09.
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Somatic symptoms are sensitive in predicting interstitial cystitis/bladder pain syndrome.
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Efficacy, Side Effects, and Monitoring of Oral Cyclosporine in Interstitial Cystitis-Bladder Pain Syndrome.
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Urology 2017; (107()):49-54 doi:10.1016/j.urology.2017.05.016.
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Development of an interstitial cystitis risk score for bladder permeability.
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Impact of Cystectomy With Urinary Diversion Upon Tracked Receipt of Opioid Prescriptions Among Patients With Interstitial Cystitis/Bladder Pain Syndrome.
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Morbidity rate and medical utilization in interstitial cystitis/painful bladder syndrome.
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International urogynecology journal 2018; (29(7)):1045-1050 doi:10.1007/s00192-018-3574-x.
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Epstein-Barr Virus as a Potential Etiology of Persistent Bladder Inflammation in Human Interstitial Cystitis/Bladder Pain Syndrome.
Jhang JF, Hsu YH, Peng CW, et al.
The Journal of urology 2018; (200(3)):590-596 doi:10.1016/j.juro.2018.03.133.
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Current Therapeutic Strategies in Clinical Urology.
Crane A, Isharwal S, Zhu H
Molecular pharmaceutics 2018; (15(8)):3010-3019 doi:10.1021/acs.molpharmaceut.8b00383.
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Cystoscopic evaluation and clinical phenotyping in interstitial cystitis/bladder pain syndrome
Acar Ö, Tarcan T
Journal of the Turkish German Gynecological Association 2019; (20(2)):117-122 doi:10.4274/jtgga.galenos.2018.2018.0102.
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Results of Sacral Neuromodulation Therapy for Urinary Voiding Dysfunction: Five-Year Experience of a Retrospective, Multicenter Study in China.
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Neuromodulation : journal of the International Neuromodulation Society 2019; (22(6)):730-737 doi:10.1111/ner.12902.
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Risk factors for increased serum creatinine level in patients with psoriasis treated with cyclosporine in a real-world practice.
Hong JR, Lee YW, Choe YB, Ahn KJ
Dermatologic therapy 2019; (32(3)):e12875 doi:10.1111/dth.12875.
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Interstitial cystitis, bladder pain syndrome, hypersensitive bladder, and interstitial cystitis/bladder pain syndrome - clarification of definitions and relationships.
Homma Y
International journal of urology : official journal of the Japanese Urological Association 2019; (26 Suppl 1()):20-24 doi:10.1111/iju.13970.
PMID: 31144731 - 19
Pathophysiology of interstitial cystitis.
Birder LA
International journal of urology : official journal of the Japanese Urological Association 2019; (26 Suppl 1()):12-15 doi:10.1111/iju.13985.
PMID: 31144735 - 20
Phenotyping of interstitial cystitis/bladder pain syndrome.
Akiyama Y, Hanno P
International journal of urology : official journal of the Japanese Urological Association 2019; (26 Suppl 1()):17-19 doi:10.1111/iju.13969.
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Phenotypic Spectrum of Pentosan Polysulfate Sodium-Associated Maculopathy: A Multicenter Study.
Hanif AM, Armenti ST, Taylor SC, et al.
JAMA ophthalmology 2019; (137(11)):1275-1282 doi:10.1001/jamaophthalmol.2019.3392.
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Calcitonin Gene-Related Peptide Negatively Regulates Alarmin-Driven Type 2 Innate Lymphoid Cell Responses.
Wallrapp A, Burkett PR, Riesenfeld SJ, et al.
Immunity 2019; (51(4)):709-723.e6 doi:10.1016/j.immuni.2019.09.005.
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The Neuropeptide CGRP Induces Bipolar Syndrome in Group 2 Innate Lymphoid Cells.
Motomura Y, Kobayashi T, Moro K
Immunity 2019; (51(4)):598-600 doi:10.1016/j.immuni.2019.09.015.
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Predictive Factors for a Satisfactory Treatment Outcome with Intravesical Botulinum Toxin A Injection in Patients with Interstitial Cystitis/Bladder Pain Syndrome.
Wang HJ, Yu WR, Ong HL, Kuo HC
Toxins 2019; (11(11)) doi:10.3390/toxins11110676.
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Pulsed Electromagnetic Field Therapy as a Complementary Alternative for Chronic Pelvic Pain Management in an Interstitial Cystitis/Bladder Pain Syndrome Patient.
Overholt TL, Ross C, Evans RJ, Walker SJ
Case reports in urology 2019; (2019()):5767568 doi:10.1155/2019/5767568.
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Clinical efficacy of submucosal injection of triamcinolone acetonide in the treatment of type II/III interstitial cystitis/bladder pain syndrome.
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Interstitial cystitis/bladder pain syndrome: The evolving landscape, animal models and future perspectives.
Akiyama Y, Luo Y, Hanno PM, et al.
International journal of urology : official journal of the Japanese Urological Association 2020; (27(6)):491-503 doi:10.1111/iju.14229.
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Homma Y, Akiyama Y, Tomoe H, et al.
International journal of urology : official journal of the Japanese Urological Association 2020; (27(7)):578-589 doi:10.1111/iju.14234.
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Correlates of 1-Year Change in Quality of Life in Patients with Urologic Chronic Pelvic Pain Syndrome: Findings from the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network.
Clemens JQ, Stephens-Shields AJ, Newcomb C, et al.
The Journal of urology 2020; (204(4)):754-759 doi:10.1097/JU.0000000000001080.
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Clinical characterization of interstitial cystitis/bladder pain syndrome in women based on the presence or absence of Hunner lesions and glomerulations.
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Lower urinary tract symptoms 2021; (13(1)):139-143 doi:10.1111/luts.12344.
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Managing Interstitial Cystitis/Bladder Pain Syndrome in Older Adults.
Gracely A, Cameron AP
Drugs & aging 2021; (38(1)):1-16 doi:10.1007/s40266-020-00810-w.
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Examination of pelvic floor muscle elasticity in patients with interstitial cystitis/bladder pain syndrome using real-time tissue elastography.
Abe-Takahashi Y, Kitta T, Ouchi M, et al.
International urogynecology journal 2022; (33(3)):619-626 doi:10.1007/s00192-021-04761-7.
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The effect of mindfulness-based stress reduction on the urinary microbiome in interstitial cystitis.
Shatkin-Margolis A, White J, Jedlicka AE, et al.
International urogynecology journal 2022; (33(3)):665-671 doi:10.1007/s00192-021-04812-z.
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Painful Bladder Syndrome/Interstitial Cystitis and High Tone Pelvic Floor Dysfunction.
Moody CC, Fashokun TB
Obstetrics and gynecology clinics of North America 2021; (48(3)):585-597 doi:10.1016/j.ogc.2021.05.010.
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Difference in electron microscopic findings among interstitial cystitis/bladder pain syndrome with distinct clinical and cystoscopic characteristics.
Lee YK, Jhang JF, Jiang YH, et al.
Scientific reports 2021; (11(1)):17258 doi:10.1038/s41598-021-96810-w.
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The diagnostic and therapeutic efficacy of cystoscopy with hydrodistension and random biopsies in clinically suspected interstitial cystitis/bladder pain syndrome.
Chen Y, Ying Z, Xiao Y, et al.
European journal of obstetrics, gynecology, and reproductive biology 2021; (265()):156-161 doi:10.1016/j.ejogrb.2021.08.025.
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Organ cross-sensitization mechanisms in chronic diseases related to the genitourinary tract.
Majima T, Sassa N
Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 2021; (57(0)):49-52 doi:10.1540/jsmr.57.49.
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Low-pressure hydrodistension induces bladder glomerulations in female patients with interstitial cystitis/bladder pain syndrome.
Hsu LN, Tsai YS, Tong YC
Neurourology and urodynamics 2022; (41(1)):296-305 doi:10.1002/nau.24818.
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Prevalence of Overactive Bladder Symptoms Among Women With Interstitial Cystitis/Bladder Pain Syndrome.
Dubinskaya A, Tholemeier LN, Erickson T, et al.
Female pelvic medicine & reconstructive surgery 2022; (28(3)):e115-e119 doi:10.1097/SPV.0000000000001166.
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Age-Related Macular Degeneration Masquerade: A Review of Pentosan Polysulfate Maculopathy and Implications for Clinical Practice.
Mukhopadhyay C, Boyce TM, Gehrs KM, et al.
Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) 2022; (11(2)):100-110 doi:10.1097/APO.0000000000000504.
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Diagnosis and Treatment of Interstitial Cystitis/Bladder Pain Syndrome.
Clemens JQ, Erickson DR, Varela NP, Lai HH
The Journal of urology 2022; (208(1)):34-42 doi:10.1097/JU.0000000000002756.
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A pilot study on oral cyclosporine A in association with fulguration for the treatment of interstitial cystitis with Hunner's lesions.
Brière R, Bouchard F, Ismail S, et al.
Neurourology and urodynamics 2022; (41(6)):1498-1504 doi:10.1002/nau.24997.
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Editorial: Special Issue "Biomarkers in Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)".
Neuhaus J, Gonsior A, Berndt-Paetz M
Diagnostics (Basel, Switzerland) 2022; (12(7)) doi:10.3390/diagnostics12071689.
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Clinical Approach to Recurrent Voiding Dysfunction, Dysuria, and Pelvic Pain Persisting for at Least 3 Months.
Kim SJ, Kim KH
International neurourology journal 2022; (26(3)):179-189 doi:10.5213/inj.2244200.100.
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Multimodal Treatment with Cognitive Behavioral Therapeutic Intervention Plus Bladder Treatment Is More Effective than Monotherapy for Patients with Interstitial Cystitis/Bladder Pain Syndrome-A Randomized Clinical Trial.
Yu WR, Jhang JF, Chen BY, et al.
Journal of clinical medicine 2022; (11(20)) doi:10.3390/jcm11206221.
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Compensatory coping and depression in women with interstitial cystitis/bladder pain syndrome.
Sutherland S, Grace Kelly A, Ryden A, et al.
Neurourology and urodynamics 2023; (42(1)):322-329 doi:10.1002/nau.25089.
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Quality-of-life impact of interstitial cystitis and other pelvic pain syndromes.
Cunningham AR, Gu L, Dubinskaya A, et al.
Frontiers in pain research (Lausanne, Switzerland) 2023; (4()):1149783 doi:10.3389/fpain.2023.1149783.
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Laser Treatment for Patients With Vulvodynia and Interstitial Cystitis/Bladder Pain Syndrome: A Case Series (The UNICORN-3 Study).
Okui N, Okui MA, Kouno Y, Nakano K
Cureus 2023; (15(7)):e41786 doi:10.7759/cureus.41786.
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Serum anandamide and lipids associated with linoleic acid can distinguish interstitial cystitis/bladder pain syndrome from overactive bladder: An exploratory study.
Torimoto K, Ueda T, Gotoh D, et al.
Lower urinary tract symptoms 2023; (15(6)):238-246 doi:10.1111/luts.12501.
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Approach of Chronic Pelvic Pain with Top Flat Magnetic Stimulation.
Salsi B, Ganassi G, Lopopolo G, et al.
Advances in urology 2023; (2023()):9983301 doi:10.1155/2023/9983301.
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The association between vulvodynia and interstitial cystitis/bladder pain syndrome: A systematic review.
Bosio S, Perossini S, Torella M, et al.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2024; (167(1)):1-15 doi:10.1002/ijgo.15538.
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Promising Experimental Treatment in Animal Models and Human Studies of Interstitial Cystitis/Bladder Pain Syndrome.
Hu JC, Tzeng HT, Lee WC, et al.
International journal of molecular sciences 2024; (25(15)) doi:10.3390/ijms25158015.
PMID: 39125584 - 53
Definition Change and Update of Clinical Guidelines for Interstitial Cystitis and Bladder Pain Syndrome.
Homma Y, Akiyama Y, Kim JH, et al.
Lower urinary tract symptoms 2024; (16(5)):e12532 doi:10.1111/luts.12532.
PMID: 39267358 - 54
Novel Application of T1ρ Magnetic Resonance Imaging for Noninvasive Assessment of Bladder Hyperpermeability Biomarkers: A Focus on Glycosaminoglycan Content.
Suyama JA, Statum SM, Mohana-Borges AVR, et al.
Neurourology and urodynamics 2025; (44(5)):1081-1089 doi:10.1002/nau.70058.
PMID: 40320728 - 55
Unraveling the complexity of bladder-centric chronic pain by intravesical contrast enhanced MRI.
Tyagi P, Maranchie J, Dhir R, et al.
Continence (Amsterdam, Netherlands) 2023; (7()) doi:10.1016/j.cont.2023.101041.
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Interstitial Cystitis/Bladder Pain Syndrome in Men.
Snipes M, Whitman W, Pontari M, et al.
Neurourology and urodynamics 2026; (45(1)):26-31 doi:10.1002/nau.70103.
PMID: 40605567 - 57
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) Diagnosis: Current Limitations and a Pragmatic Clinical Diagnostic Definition.
Werneburg GT, Moldwin R, Lowell Parsons C, et al.
Neurourology and urodynamics 2026; (45(1)):32-38 doi:10.1002/nau.70112.
PMID: 40626422 - 58
Integrative Diagnostic Model Combining Urinary Biomarkers and Clinical Parameters to Improve Diagnostic Performance in Interstitial Cystitis/Bladder Pain Syndrome.
Chen YC, Tian JH, Kuo HC
European urology open science 2025; (82()):192-200 doi:10.1016/j.euros.2025.10.021.
PMID: 41322958 - 59
Advances in Cytokines and Inflammatory Mechanisms in the Pathogenesis of Interstitial Cystitis/Bladder Pain Syndrome.
Xiao Y, Zhu D, Zhou X
Biomolecules 2026; (16(1)) doi:10.3390/biom16010138.
PMID: 41594678