Research & Literature

Diverse genetic aetiologies and clinical outcomes of paediatric hypoparathyroidism.

Kim JH, Shin YL, Yang S, et al.

Clinical endocrinology 2015; (83(6)):790-6 doi:10.1111/cen.12944.

Synchronous Diaphragmatic Flutter Secondary to Primary Hypoparathyroidism in a Dog.

Vrabelova D, Gilor C, Habing A, et al.

Journal of the American Animal Hospital Association 2015; (51(6)):392-5 doi:10.5326/JAAHA-MS-6235.

An approach to the diagnosis and management of a case presenting with recurrent hypomagnesemia secondary to the chronic use of a proton pump inhibitor.

dos Santos LM, Guerra RA, Lazaretti-Castro M, et al.

Magnesium research 2015; (28(4)):136-45 doi:10.1684/mrh.2015.0395.

Endocrine dysfunction in hereditary hemochromatosis.

Pelusi C, Gasparini DI, Bianchi N, Pasquali R

Journal of endocrinological investigation 2016; (39(8)):837-47 doi:10.1007/s40618-016-0451-7.

Suppression of Parathyroid Hormone in a Patient with Severe Magnesium Depletion.

Mutnuri S, Fernandez I, Kochar T

Case reports in nephrology 2016; (2016()):2608538 doi:10.1155/2016/2608538.

Hypoparathyroidism and pseudohypoparathyroidism: etiology, laboratory features and complications.

Lopes MP, Kliemann BS, Bini IB, et al.

Archives of endocrinology and metabolism 2016; (60(6)):532-536 doi:10.1590/2359-3997000000221.

Proton pump inhibitor-induced hypomagnesaemia and hypocalcaemia: case review.

Sivakumar J

International journal of physiology, pathophysiology and pharmacology 2016; (8(4)):169-174.

A Case of Renal Tubular Acidosis with Sjogren's Syndrome Showing Paradoxical Block of PTH Due to Severe Hypomagnesemia.

Kumar BV, Sivalingam M, Kumaran GS, Balakrishnan B

Indian journal of clinical biochemistry : IJCB 2017; (32(4)):496-499 doi:10.1007/s12291-016-0629-y.

Hypocalcemia Presenting as Life Threatening Torsades de Pointes with Prolongation of QTc Interval.

Chhabra ST, Mehta S, Chhabra S, et al.

Indian journal of clinical biochemistry : IJCB 2018; (33(2)):235-238 doi:10.1007/s12291-017-0684-z.

Diagnosis and treatment of hypoparathyroidism: a position statement from the Brazilian Society of Endocrinology and Metabolism.

Maeda SS, Moreira CA, Borba VZC, et al.

Archives of endocrinology and metabolism 2018; (62(1)):106-124 doi:10.20945/2359-3997000000015.

Immunosuppressive therapy of autoimmune hypoparathyroidism in a patient with activating autoantibodies against the calcium-sensing receptor.

Chamberlin M, Kemp EH, Weetman AP, et al.

Clinical endocrinology 2019; (90(1)):214-221 doi:10.1111/cen.13886.

Physiology of Parathyroid Hormone.

Goltzman D

Endocrinology and metabolism clinics of North America 2018; (47(4)):743-758 doi:10.1016/j.ecl.2018.07.003.

Medical Hypoparathyroidism.

Siraj N, Hakami Y, Khan A

Endocrinology and metabolism clinics of North America 2018; (47(4)):797-808 doi:10.1016/j.ecl.2018.07.006.

Genetic Disorders of Parathyroid Development and Function.

Gordon RJ, Levine MA

Endocrinology and metabolism clinics of North America 2018; (47(4)):809-823 doi:10.1016/j.ecl.2018.07.007.

Hypoparathyroidism and the Kidney.

Peacock M

Endocrinology and metabolism clinics of North America 2018; (47(4)):839-853 doi:10.1016/j.ecl.2018.07.009.

Standards of care for hypoparathyroidism in adults: a Canadian and International Consensus.

Khan AA, Koch CA, Van Uum S, et al.

European journal of endocrinology 2019; (180(3)):P1-P22.

A New Era for Chronic Management of Hypoparathyroidism: Parathyroid Hormone Peptides.

Marcucci G, Brandi ML

Frontiers of hormone research 2019; (51()):165-171 doi:10.1159/000491047.

Conventional Treatment of Hypoparathyroidism.

Marcucci G, Brandi ML

Frontiers of hormone research 2019; (51()):160-164 doi:10.1159/000491046.

Calcium.

Weaver CM, Peacock M

Advances in nutrition (Bethesda, Md.) 2019; (10(3)):546-548 doi:10.1093/advances/nmy086.

Clinical burden and healthcare resource utilization among patients with chronic hypoparathyroidism, overall and by adequately vs not adequately controlled disease: a multi-country chart review.

Chen K, Krasner A, Li N, et al.

Journal of medical economics 2019; (22(11)):1141-1152 doi:10.1080/13696998.2019.1624081.

Gitelman's syndrome with hyperphosphatemia, effectively responding to single oral magnesium oxide administration: A case report.

Miya A, Nakamura A, Kameda H, et al.

Medicine 2019; (98(28)):e16408 doi:10.1097/MD.0000000000016408.

Defining the Characteristics of Chronic Hypoparathyroidism Not Adequately Controlled on Conventional Therapy: Consensus Findings of Three European Delphi Panels.

Iqbal K, Dass N, Gip C, et al.

Advances in therapy 2019; (36(11)):3007-3016 doi:10.1007/s12325-019-01102-5.

[Hypoparathyroidism - un underestimated problem?]

Petersenn S, Bojunga J, Brabant G, et al.

MMW Fortschritte der Medizin 2019; (161(Suppl 7)):12-20 doi:10.1007/s15006-019-1174-4.

Nephrocalcinosis, Renal Dysfunction, and Calculi in Patients With Primary Hypoparathyroidism on Long-Term Conventional Therapy.

Saha S, Kandasamy D, Sharma R, et al.

The Journal of clinical endocrinology and metabolism 2020; (105(4)) doi:10.1210/clinem/dgz319.

Falciparum Malaria Presenting With Tetany: Endocrinopathies Associated With Falciparum Malaria.

Aijazi I, Chaudary M, Adam Mukhtar SH, Abdulla Al Shama FM

Journal of Ayub Medical College, Abbottabad : JAMC 2020; (32(1)):136-138.

Parathyroid Hormone Replacement versus Oral Calcium and Active Vitamin D Supplementation in Hypoparathyroidism: A Meta-analysis.

Palui R, Das RR, Roy A, et al.

Indian journal of endocrinology and metabolism 2020; (24(2)):206-214 doi:10.4103/ijem.IJEM_579_19.

Pseudohypoparathyroidism presenting with seizures: a case report and literature review.

Najim MS, Ali R, Awad M, Omer A

Intractable & rare diseases research 2020; (9(3)):166-170 doi:10.5582/irdr.2020.03014.

Recombinant human parathyroid hormone (1-84) is effective in CASR-associated hypoparathyroidism.

Hawkes CP, Shulman DI, Levine MA

European journal of endocrinology 2020; (183(6)):K13-K21.

Hypoparathyroidism in a Case of Transfusion Dependent Thalassemia.

Majumder A, Basu S

Journal of the ASEAN Federation of Endocrine Societies 2020; (35(1)):129-132 doi:10.15605/jafes.035.01.23.

[Differential diagnosis of normocalcemic hyperparathyroidism and idiopathic hypercalciuria on the example of clinical case].

Runova GE, Golounina OO, Glinkina IV, et al.

Problemy endokrinologii 2020; (66(6)):13-17 doi:10.14341/probl12677.

Challenges in the management of chronic hypoparathyroidism.

Zavatta G, Clarke BL

Endocrine connections 2020; (9(10)):R229-R240.

Renal complications in patients with chronic hypoparathyroidism on conventional therapy: a systematic literature review : Renal disease in chronic hypoparathyroidism.

Gosmanova EO, Houillier P, Rejnmark L, et al.

Reviews in endocrine & metabolic disorders 2021; (22(2)):297-316 doi:10.1007/s11154-020-09613-1.

Risk of Nephrolithiasis and Nephrocalcinosis in Patients with Chronic Hypoparathyroidism: A Retrospective Cohort Study.

Ketteler M, Chen K, Gosmanova EO, et al.

Advances in therapy 2021; (38(4)):1946-1957 doi:10.1007/s12325-021-01649-2.

Hypocalcemia not related to chronic kidney disease: Answers.

Zeybek C, Akin O, Bolat A

Pediatric nephrology (Berlin, Germany) 2021; (36(10)):3105-3107 doi:10.1007/s00467-021-05036-5.

The axial spondyloarthritis clinical phenotype in idiopathic hypoparathyroidism: critical review of concept that muscular hypercontractility can induce enthesopathy lesions.

Masi AT, Jorgenson LC, Ilahi S

Clinical and experimental rheumatology 2021; (39(6)):1422-1431 doi:10.55563/clinexprheumatol/5l89p0.

Maternal GNAS Contributes to the Extra-Large G Protein α-Subunit (XLαs) Expression in a Cell Type-Specific Manner.

Cui Q, Aksu C, Ay B, et al.

Frontiers in genetics 2021; (12()):680537 doi:10.3389/fgene.2021.680537.

PaTH Forward: A Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial of TransCon PTH in Adult Hypoparathyroidism.

Khan AA, Rejnmark L, Rubin M, et al.

The Journal of clinical endocrinology and metabolism 2022; (107(1)):e372-e385 doi:10.1210/clinem/dgab577.

Is All Hypocalcemia Due to Low Parathyroid Hormone?: An Unusual Case of Pseudohypoparathyroidism in a Young and Healthy Patient.

Shah FA, Fujikawa P, Braford M, et al.

Cureus 2021; (13(7)):e16243 doi:10.7759/cureus.16243.

A child with tetany, convulsions, and nephrocalcinosis: Answers.

Karunakar P, Krishnamurthy S, Rajavelu TN, et al.

Pediatric nephrology (Berlin, Germany) 2021; (36(12)):4119-4122 doi:10.1007/s00467-021-05238-x.

Identifying Clinical Characteristics of Hypoparathyroidism in Turkey: HIPOPARATURK-NET Study.

Konca Degertekin C, Gogas Yavuz D, Pekkolay Z, et al.

Calcified tissue international 2022; (110(2)):204-214 doi:10.1007/s00223-021-00908-2.

[CME: Hypocalcemia and Hypoparathyroidism].

Burget L

Praxis 2021; (110(13)):703-708 doi:10.1024/1661-8157/a003751.

Novel PTH Gene Mutations Causing Isolated Hypoparathyroidism.

Hawkes CP, Al Jubeh JM, Li D, et al.

The Journal of clinical endocrinology and metabolism 2022; (107(6)):e2449-e2458 doi:10.1210/clinem/dgac086.

Vitamin D and Phosphate Interactions in Health and Disease.

Akimbekov NS, Digel I, Sherelkhan DK, Razzaque MS

Advances in experimental medicine and biology 2022; (1362()):37-46 doi:10.1007/978-3-030-91623-7_5.

Early Diagnosis of Pseudohypoparathyroidism before the Development of Hypocalcemia in a Young Infant.

Hwang SK, Shim YJ, Oh SH, Jang KM

Children (Basel, Switzerland) 2022; (9(5)) doi:10.3390/children9050723.

Quantifying Brain Iron in Hereditary Hemochromatosis Using R2* and Susceptibility Mapping.

Sethi SK, Sharma S, Gharabaghi S, et al.

AJNR. American journal of neuroradiology 2022; (43(7)):991-997 doi:10.3174/ajnr.A7560.

The Reality of Hypoparathyroidism After Thyroidectomy: Which Risk Factors are Effective? Single-Center Study.

Akgun IE, Unlu MT, Aygun N, et al.

Sisli Etfal Hastanesi tip bulteni 2022; (56(2)):262-269 doi:10.14744/SEMB.2022.24356.

Evaluation and Management of Hypoparathyroidism Summary Statement and Guidelines from the Second International Workshop.

Khan AA, Bilezikian JP, Brandi ML, et al.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2022; (37(12)):2568-2585 doi:10.1002/jbmr.4691.

Hypoparathyroidism: update of guidelines from the 2022 International Task Force.

Clarke BL

Archives of endocrinology and metabolism 2022; (66(5)):604-610.

Association of Calcium and Phosphate Levels with Incident Chronic Kidney Disease in Patients with Hypoparathyroidism: A Retrospective Case-Control Study.

Gosmanova EO, Ayodele O, Chen K, et al.

International journal of endocrinology 2022; (2022()):6078881 doi:10.1155/2022/6078881.

Coronary artery disease and its vascular associates in patients with chronic nonsurgical hypoparathyroidism.

Saha S, Narang R, Goswami R, et al.

Clinical endocrinology 2023; (98(4)):505-515 doi:10.1111/cen.14872.

Regulation of FGF23 production and phosphate metabolism by bone-kidney interactions.

Agoro R, White KE

Nature reviews. Nephrology 2023; (19(3)):185-193 doi:10.1038/s41581-022-00665-x.

Denosumab-induced hypocalcemia post bariatric surgery-a severe and protracted course: a case report.

Awang MH, Hatta SFWM, Mohamad AF, Ghani RA

Journal of medical case reports 2023; (17(1)):73 doi:10.1186/s13256-023-03764-w.

Transient Loss of Consciousness Associated With Severe Hypocalcemia and QT Prolongation Due to Primary Hypoparathyroidism in an Adolescent Girl.

Miyao M, Aoki Y, Mizushiro N, et al.

Cureus 2023; (15(1)):e34352 doi:10.7759/cureus.34352.

Association of Serum Calcium and Phosphate With Incident Cardiovascular Disease in Patients With Hypoparathyroidism.

Kaul S, Ayodele O, Chen K, et al.

The American journal of cardiology 2023; (194()):60-70 doi:10.1016/j.amjcard.2023.01.029.

Cracking the natriuresis puzzle: Insight from structural biology.

Tian XY, Wong WT, Zhu Z

Med (New York, N.Y.) 2023; (4(4)):223-225 doi:10.1016/j.medj.2023.03.004.

Multiple brown tumors: a bone complication due to long-term untreated pseudohypoparathyroidism.

Gonnelli S, Briot K, Cormier C, et al.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2024; (35(1)):195-199 doi:10.1007/s00198-023-06878-5.

Case Report: Calcium sensing receptor gene gain of function mutations: a case series and report of 2 novel mutations.

Ali DS, Marini F, Alsarraf F, et al.

Frontiers in endocrinology 2023; (14()):1215036 doi:10.3389/fendo.2023.1215036.

Multiple electrolyte disorders triggered by proton pump inhibitor-induced hypomagnesemia: Case reports with a mini-review of the literature.

Souza CC, Rigueto LG, Santiago HC, et al.

Clinical nephrology. Case studies 2024; (12()):6-11 doi:10.5414/CNCS111284.

A Review of New Concepts in Iron Overload.

Sohal A, Kowdley KV

Gastroenterology & hepatology 2024; (20(2)):98-107.

Incident comorbidities in patients with chronic hypoparathyroidism after thyroidectomy: a multicenter nationwide study.

Díez JJ, Anda E, Pérez-Corral B, et al.

Frontiers in endocrinology 2024; (15()):1348971 doi:10.3389/fendo.2024.1348971.

A delicate balance: the challenges of hypoparathyroidism.

Papaioannou G, Mannstadt M

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2024; (39(4)):377-381 doi:10.1093/jbmr/zjae049.

Incidence of Post-Thyroidectomy Hypoparathyroidism and Associated Preoperative and Intraoperative Risk Factors.

Al-Hakami HA, Alsolamy RM, I Awad B, et al.

Cureus 2024; (16(3)):e56585 doi:10.7759/cureus.56585.

A Very Rare Side Effect of a Very Commonly Used Drug: Pantoprazole-induced Seizure.

Anandan S, Rajendran SS, Somarajan SA, Udayan A

The Journal of the Association of Physicians of India 2024; (72(8)):89 doi:10.59556/japi.72.0579.

A novel frameshift variant of GATA3 (p.Ala17ProfsTer178) responsible for HDR syndrome in a Japanese family.

Hasegawa Y, Segawa T, Chida A, et al.

Endocrine journal 2024; (71(11)):1077-1086 doi:10.1507/endocrj.EJ24-0147.

Risk Factors for Transient and Permanent Hypoparathyroidism Following Thyroidectomy: A Comprehensive Review.

Maheshwari M, Khan IA

Cureus 2024; (16(8)):e66551 doi:10.7759/cureus.66551.

Efficacy and Safety of TransCon PTH in Adults With Hypoparathyroidism: 52-Week Results From the Phase 3 PaTHway Trial.

Clarke BL, Khan AA, Rubin MR, et al.

The Journal of clinical endocrinology and metabolism 2025; (110(4)):951-960 doi:10.1210/clinem/dgae693.

Case report: Familial hypoparathyroidism with elevated parathyroid hormone due to an inactivating PTH mutation.

Mukhtar N, Alghamdi B, Alswailem M, et al.

Frontiers in endocrinology 2024; (15()):1415639 doi:10.3389/fendo.2024.1415639.

Proton pump inhibitor-induced hypomagnesemia, a rare cause of reversible delirium: A case report with literature review.

Zhao W, Zhang J, Jia H, et al.

Medicine 2024; (103(40)):e39729 doi:10.1097/MD.0000000000039729.

An electrolyte disturbance masquerading as a panic attack.

Wildermuth A, Lantz M, Sagers E

JAAPA : official journal of the American Academy of Physician Assistants 2025; (38(1)):e1-e4 doi:10.1097/01.JAA.0000000000000152.

Hypoparathyroidism: diagnosis, management and emerging therapies.

Khan S, Khan AA

Nature reviews. Endocrinology 2025; (21(6)):360-374 doi:10.1038/s41574-024-01075-8.

Adaptation and validation of the French version of the Hypoparathyroid Patient Questionnaire 28 (HPQ28) in the ComPaRe-Epi-Hypo e-cohort.

Bertocchio JP, Soyer J, Grosset N, et al.

JBMR plus 2025; (9(3)):ziaf011 doi:10.1093/jbmrpl/ziaf011.

Neurological Manifestations Associated With Hypomagnesemia Due to Proton-Pump Inhibitors: A Case Series.

James L, Rajan G, Devarajan D, Mohan A

Cureus 2025; (17(1)):e78229 doi:10.7759/cureus.78229.

Impaired renal function in patients with permanent hypoparathyroidism after thyroidectomy: analysis of a nationwide cohort in Spain.

Díez JJ, Anda E, Pérez-Corral B, et al.

Endocrine 2025; (88(3)):826-835 doi:10.1007/s12020-025-04187-x.

Paradoxical Inadequate Parathyroid Hormone Secretion Secondary to Severe Hypomagnesemia: A Review of the Literature.

Albert A, Hinkel UP, Bohlender T, et al.

Kidney medicine 2025; (7(8)):101046 doi:10.1016/j.xkme.2025.101046.

Seizures and hypoparathyroidism post-thyroidectomy: Fahr's syndrome.

Mundada SM, Sanivarapu TR, Kataveni S

BMJ case reports 2025; (18(9)) doi:10.1136/bcr-2025-266319.

Health-related quality of life in a cohort of 1070 patients with hypoparathyroidism.

Siggelkow H, Vokes T, Gittoes N, et al.

European journal of endocrinology 2025; (193(4)):428-439 doi:10.1093/ejendo/lvaf169.

Value Contribution of Palopegteriparatide in Adult Patients with Chronic Hypoparathyroidism using Multicriteria Decision Analysis (MCDA).

Díez JJ, Badia X, Abad R, et al.

Advances in therapy 2025; (42(12)):6234-6247 doi:10.1007/s12325-025-03396-0.

Hydrochlorothiazide with salt restriction in nonsurgical hypoparathyroidism: a placebo-controlled single-blinded randomized crossover trial assessing efficacy and safety.

Jha V, Mukherjee S, Bhadada SK, et al.

JBMR plus 2025; (9(12)):ziaf174 doi:10.1093/jbmrpl/ziaf174.

Palopegteriparatide for Adults with Chronic Hypoparathyroidism: Skeletal Dynamics Through 3 yr of the Phase 2 paTH Forward Trial.

Rubin MR, Clarke BL, Hofbauer LC, et al.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2026; doi:10.1093/jbmr/zjag013.